Yini i-Doxepin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Doxepin iyimithi eyilungu leqembu lezidakamizwa ezibizwa ngokuthi ama-tricyclic antidepressants, nakuba isetshenziselwa ezinye izimo ezingaphezu kokucindezeleka. Udokotela wakho angase akubhalele ukukusiza ngezinkinga zokulala, ukukhathazeka, noma izinhlobo ezithile zobuhlungu obungapheli. Le mithi eguquguqukayo isineminyaka eminingi ikhona futhi ingasebenza kahle uma isetshenziswa ngendlela efanele ngaphansi kokuqondisa kwezokwelapha.

Yini i-Doxepin?

I-Doxepin iyimithi kadokotela esebenza ngokuthinta amakhemikhali athile ebuchosheni bakho abizwa ngokuthi ama-neurotransmitters. Iza ngesimo samaphilisi futhi ithathwa ngomlomo, ngokuvamile kanye noma kabili ngosuku kuye ngokuthi yisiphi isimo osilaphayo. Imithi iyatholakala ngamandla ahlukene, kusukela kuma-capsules angu-10mg kuya kuma-150mg.

Le mithi yaqala ukuthuthukiswa njenge-antidepressant kodwa iye yazibonakalisa ilusizo ezimweni eziningana ezinye eminyakeni edlule. Udokotela wakho uzonquma umthamo ofanele ngokuya ngezidingo zakho ezithile nomlando wezokwelapha. Kubalulekile ukwazi ukuthi i-doxepin idinga incwadi kadokotela futhi kufanele isetshenziswe kuphela ngaphansi kokuqondisa kwezokwelapha.

Yini i-Doxepin Esetshenziselwa Yona?

I-Doxepin iphatha izimo eziningana ezihlukene, ukucindezeleka nokukhathazeka kuyizizathu ezivame kakhulu odokotela abayibhala ngazo. Abantu abaningi futhi bayithola ilusizo ezinkingeni zokulala, ikakhulukazi uma benobunzima bokulala ebusuku. Imithi ingase ibe usizo ikakhulukazi uma ubhekene nezinkinga zemizwa nezinkinga zokulala ngesikhathi esisodwa.

Ngaphandle kwezimo zempilo yengqondo, i-doxepin ngezinye izikhathi isiza ngezimo zobuhlungu obungapheli nezinkingana ezithile zesikhumba ezibangela ukuluma. Nazi izimo eziyinhloko ezingazelapha:

• Ukucindezeleka, ikakhulukazi uma kuhambisana nokukhathazeka
• Izifo zokukhathazeka nokuhlaselwa yisithukuthezi
• Ukuqwasha nezinye iziphazamiso zokulala
• Izimo zobuhlungu obungapheli njenge-fibromyalgia
• Izinhlobo ezithile zezimo zesikhumba ezilumayo

Udktela wakho uzohlola izimpawu zakho ezithile kanye nomlando wakho wezokwelapha ukuze anqume ukuthi i-doxepin iyindlela efanele kuwe yini. Ngezinye izikhathi isetshenziswa kanye neminye imithi njengengxenye yohlelo lokwelapha olubanzi.

Isebenza Kanjani I-Doxepin?

I-Doxepin isebenza ngokwandisa amazinga amakhemikhali athile obuchopho abizwa ngokuthi i-serotonin kanye ne-norepinephrine. Lawa makhemikhali asiza ukulawula imizwa yakho, amaphethini okulala, kanye nokuqonda ubuhlungu. Cabanga ngayo njengokusiza ukubuyisela ibhalansi engcono ohlelweni lokuxhumana lobuchopho bakho.

Lo muthi uthathwa njengomuthi onamandla ngokulinganisela phakathi kwemithi yokucindezeleka futhi ngokuvamile kuthatha amasonto amaningana ukukhombisa imiphumela yawo ephelele. Ngokungafani neminye imithi yokucindezeleka emisha, i-doxepin nayo inezindawo ze-antihistamine, okuchaza ukuthi kungani ingasiza ikakhulu ezinkingeni zokulala nokuluma. Lesi senzo esiphindwe kabili senza ukuthi sihluke phakathi kwemithi yezifo zengqondo.

Uma isetshenziselwa ukulala, i-doxepin isebenza ngendlela ehlukile kunamaphilisi okulala avamile. Esikhundleni sokukuthulisa nje, isiza ukulawula umjikelezo wakho wokulala wemvelo futhi ingathuthukisa izinga lokulala kwakho ngokuhamba kwesikhathi.

Kufanele Ngiyithathe Kanjani I-Doxepin?

Thatha i-doxepin ngendlela udokotela wakho ayikuyala ngayo, ngokuvamile kanye ngosuku ngesikhathi sokulala noma ihlukaniswe ibe izilinganiso ezimbili noma ezintathu usuku lonke. Ungayithatha ngaphandle kokudla noma ngaphandle kokudla, kodwa ukuyithatha nokudla kungasiza ukunciphisa ukuphazamiseka kwesisu uma uhlangabezana nanoma yikuphi. Gwinya amaphilisi wonke ngenkomishi yamanzi egcwele.

Uma uthatha i-doxepin ukuze ulale, udokotela wakho cishe uzokuncoma ukuthi uyithathe imizuzu engama-30 kuya ehore ngaphambi kokulala. Ngokucindezeleka noma ukukhathazeka, ungase uyithathe ngezilinganiso ezihlukanisiwe usuku lonke noma njengomthamo owodwa ngesikhathi sokulala. Ungalokothi uchoboze noma uvule amaphilisi, ngoba lokhu kungathinta indlela umuthi ogxiliswa ngayo.

Kuyasiza ukuthatha i-doxepin ngesikhathi esifanayo nsuku zonke ukuze kugcinwe amazinga aqhubekayo emzimbeni wakho. Uma uyithatha ukuze ulale, zama ukusungula umkhuba wokulala ovamile. Gwema utshwala ngenkathi uthatha lo muthi, ngoba ungenza ukozela kanye neminye imiphumela engemihle.

Ngingayithatha isikhathi esingakanani i-Doxepin?

Ubude bokwelashwa nge-doxepin buhlukahluka kakhulu kuye ngesimo sakho nokuthi usabela kanjani emuthini. Ngokucindezeleka noma ukukhathazeka, ungase udinge ukuyithatha izinyanga eziningana kuya ngonyaka noma ngaphezulu. Izinkinga zokulala zingase zidinge ukwelashwa kwesikhathi esifushane, nakuba abanye abantu bezuza ekusebenziseni isikhathi eside.

Udkt wakho ngokuvamile uzoqala ngomthamo ophansi futhi awunyuse kancane kancane emasontweni ambalwa aze afinyelele inani elisebenzayo kakhulu. Kubalulekile ukunika umuthi isikhathi sokusebenza, njengoba ungase ungazizwa izinzuzo ezigcwele amasonto angu-4-6. Ungayeki ukuthatha i-doxepin ngokuzumayo, ngoba lokhu kungabangela izimpawu zokuhoxisa.

Ukuqokwa okuvamile kokulandela udokotela wakho kubalulekile ukuqapha inqubekela phambili yakho nokulungisa uhlelo lwakho lokwelapha njengoba kudingeka. Abanye abantu bangase badinge ukuthatha i-doxepin isikhathi eside, kanti abanye bangase bakwazi ukunciphisa kancane kancane umthamo wabo futhi ekugcineni bayeke umuthi.

Yiziphi Imiphumela Engemihle ye-Doxepin?

Njengayo yonke imithi, i-doxepin ingabangela imiphumela engemihle, nakuba kungewona wonke umuntu oyitholayo. Imiphumela engemihle evame kakhulu ivame ukuba mnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Abantu abaningi bathola ukuthi ukuqala ngomthamo ophansi nokwandisa kancane kancane kusiza ukunciphisa le miphumela.

Nawa imiphumela engemihle evame kakhulu ongase uyithole:

• Ukozela noma ukuzwa ubuthongo emini
• Umlomo owomile nokwanda komzwelo wokoma
• Isiyezi, ikakhulukazi lapho usukuma ngokushesha
• Ukuqunjelwa noma izinguquko ekuhambeni kwamathumbu
• Ukubona okungacacile noma ubunzima bokugxila
• Ukukhuluphala noma izinguquko ekudleni
• Ubunzima bokuchama

Iningi lalemiphumela emibi liyalawuleka futhi livame ukuncipha ngokuhamba kwesikhathi. Ukuphuza amanzi amaningi kungasiza ngomlomo owomile, futhi ukuvuka kancane kunganciphisa isiyezi.

Ezinye izimo ezingavamile kodwa ezingathi sína zidinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ukudideka okukhulu noma izinkinga zenkumbulo
• Ukuphefumula kanzima noma ukugwinya
• Ukuphendula kwesikhumba okukhulu noma ukuqubuka
• Imicabango yokuzilimaza, ikakhulukazi kubantu abadala abasebancane
• Ukuhlaselwa yisifo noma ukuquleka

Uma uhlangabezana nanoma yiziphi zale miphumela emibi engathi sína, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezempilo eziphuthumayo. Ukuphepha kwakho yikho okubaluleke kakhulu.

Ubani Ongafanele Athathe I-Doxepin?

I-Doxepin ayifanele wonke umuntu, futhi izimo ezithile zezokwelapha noma imithi kungayenza ingaphephile ukuyisebenzisa. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha nemithi yamanje ngaphambi kokukuchazela i-doxepin ukuze aqinisekise ukuthi iphephile kuwe.

Akufanele uthathe i-doxepin uma unezimo ezithile zenhliziyo, ikakhulukazi ukuhlaselwa yinhliziyo kwakamuva noma izinkinga ezinkulu zesigqi senhliziyo. Umuthi ungalimaza futhi uma une-glaucoma engalashwanga ye-narrow-angle noma isifo sesibindi esibi. Uma uthatha imithi ethile ebizwa ngokuthi ama-MAO inhibitors, uzodinga ukulinda okungenani izinsuku eziyi-14 ngemva kokuyeka ngaphambi kokuqala i-doxepin.

Nazi ezinye izimo lapho i-doxepin ingase ingafaneleki khona:

• Isifo sezinso noma sesibindi esibi
• Umlando wokuhlaselwa yisifo noma isithuthwane
• Ukwanda kwendlala yesinye noma izinkinga zokugcinwa komchamo
• Izinkinga ezinkulu zokuphefumula noma i-sleep apnea
• Umlando wokuzama ukuzibulala noma ukucindezeleka okukhulu
• Ukukhulelwa noma ukuncelisa (xoxa nodokotela wakho)

Ubudala nabo buyinto ebalulekile, njengoba abadala bengase bazwe imiphumela ye-doxepin kakhulu futhi bangase badinge imithamo ephansi noma ukuqashwa okuseduze. Udokotela wakho uzoqaphela izinzuzo uma ziqhathaniswa nezingozi ezingaba khona esimweni sakho esithile.

Amagama Omkhiqizo we-Doxepin

I-Doxepin iyatholakala ngaphansi kwamagama amaningi omkhiqizo, nakuba ivame ukunqunywa njengomuthi ojwayelekile. Amagama omkhiqizo aziwa kakhulu afaka i-Sinequan, Adapin, kanye ne-Silenor. I-Silenor ivunyelwe ngokuqondile ukuze ilashwe ukuqwasha futhi iza ngemithamo ephansi kunezinguqulo ezisetshenziselwa ukucindezeleka.

Inguqulo ejwayelekile ye-doxepin isebenza kahle njengezinguqulo zegama lomkhiqizo futhi ivame ukungabizi kakhulu. Ikhemisi lakho lingase lithathe indawo yenguqulo ejwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo. Zonke izinguqulo ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngendlela efanayo.

Ezinye Izindlela Zokwelapha ze-Doxepin

Uma i-doxepin ingakulungele noma ingakunikezi impumuzo oyidingayo, kunezindlela eziningi zokwelapha ezingase zicatshangelwe udokotela wakho. Ukucindezeleka nokukhathazeka, ama-antidepressants amasha afana ne-SSRIs (njenge-sertraline noma i-escitalopram) noma ama-SNRIs (njenge-venlafaxine) angase abe yizinketho ezinemiphumela emincane.

Ezinkingeni zokulala, ezinye izindlela zingabandakanya ezinye izidambisi zokucindezeleka ezifana ne-trazodone, noma imithi ethile yokulala efana ne-zolpidem noma i-eszopiclone. Izindlela ezingezona zemithi ezifana ne-cognitive behavioral therapy for insomnia (CBT-I) nazo zingase zisebenze kahle kakhulu ezinkingeni zokulala.

Udokotela wakho uzokusiza ukuthi uhlole lezi zindlela ezinye ngokusekelwe ezimpawini zakho ezithile, umlando wezokwelapha, kanye nemigomo yokwelapha. Ngezinye izikhathi inhlanganisela yezindlela isebenza kahle kakhulu.

Ingabe i-Doxepin Ingcono Kune-Amitriptyline?

Kokubili i-doxepin ne-amitriptyline ziyizidambisi zokucindezeleka ze-tricyclic ezisebenza ngendlela efanayo ekwelapheni ukucindezeleka, ukukhathazeka, nezinhlobo ezithile zobuhlungu obungapheli. Ukukhetha phakathi kwazo kuvame ukuncika emiphumeleni emibi kanye nokuphendula komuntu ngamunye kunokuthi enye ibe ngcono ngokuqinisekile kunenye.

I-Doxepin ivame ukuba ne-sedating kune-amitriptyline, okungasiza uma ubhekene nezinkinga zokulala kanye nezinye izimpawu zakho. Kodwa-ke, i-amitriptyline ingase ithandwe ngezinhlobo ezithile zobuhlungu obungapheli, ikakhulukazi ama-migraines nobuhlungu bemizwa. Zombili lezi zithako zemithi zinezimpawu ezifanayo, nakuba abanye abantu bezibekezelela ngcono kunabanye.

Udokotela wakho uzocabangela izimpawu zakho ezithile, umlando wakho wezokwelapha, neminye imithi lapho ekhetha phakathi kwalezi zinketho. Ngezinye izikhathi kuyindaba yokuzama eyodwa bese ubona ukuthi uphendula kanjani ngaphambi kokwenza isinqumo sokugcina.

Imibuzo Evame Ukubuzwa Mayelana ne-Doxepin

Ingabe i-Doxepin iphephile ezigulini zenhliziyo?

I-Doxepin idinga ukucatshangelwa ngokucophelela kubantu abanezifo zenhliziyo, njengoba ingathinta isigqi senhliziyo nomfutho wegazi. Uma unomlando wezinkinga zenhliziyo, udokotela wakho uzodinga ukuhlola izingozi nezinzuzo ngokucophelela. Kwezinye izimo, imithi ingase isetshenziswe ngokuqapha eduze, kanti kwezinye, ukwelashwa okuhlukile kungase kuphephe.

Udokotela wakho angase ancome i-electrocardiogram (EKG) ngaphambi kokuqala i-doxepin ukuze ahlolisise isigqi senhliziyo yakho. Ukuqapha njalo ngesikhathi sokwelashwa kuvame ukudingeka uma unokukhathazeka okuthile ngenhliziyo. Ungalokothi uqale noma uyeke i-doxepin ngaphandle kokuqashwa kwezokwelapha uma unezinkinga zenhliziyo.

Ngingenzani uma ngiphuzile i-Doxepin eningi ngengozi?

Uma ngengozi uphuza i-doxepin eningi kunaleyo ebekiwe, xhumana nodokotela wakho ngokushesha noma shayela ukulawulwa kwe-poison. Ukuphuza i-doxepin eningi kungaba yingozi futhi kungase kubangele ukozela okukhulu, ukudideka, ukushaya kwenhliziyo okungajwayelekile, noma ubunzima bokuphefumula. Ungazami ukusingatha ukweqisa ngawodwa.

Izimpawu zokweqisa umthamo we-doxepin zihlanganisa ukozela okukhulu, ukudideka, ukuquleka, ubunzima bokuphefumula, noma ukulahlekelwa ukwazi. Uma umuntu engazi noma enobunzima bokuphefumula, shayela izinsiza eziphuthumayo ngokushesha. Gcina ibhodlela lomuthi unawe uma ufuna usizo lwezokwelapha ukuze abahlinzeki bezempilo bazi kahle ukuthi yini ethathwe.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Doxepin?

Uma uphuthelwa umthamo we-doxepin, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi.

Uma uthatha i-doxepin ukuze ulale futhi uphuthelwa umthamo wakho wokulala, ungase ukhethe ukuweqa kunokuthi uwuthathe ebusuku, ngoba lokhu kungase kuthinte isimiso sakho sokulala ngosuku olulandelayo. Xoxa nodokotela wakho ngendlela engcono kakhulu yesimo sakho esithile.

Ngingayeka nini ukuthatha i-Doxepin?

Ungalokothi uyeke ukuthatha i-doxepin ngokuzumayo, ngoba lokhu kungabangela izimpawu zokuhoxiswa njengokucasuka, ikhanda, isiyezi, kanye nezinguquko zemizwa. Udokotela wakho uzokwenza uhlelo lokunciphisa kancane umthamo wakho emasontweni amaningana noma izinyanga uma sekuyisikhathi sokuyeka umuthi. Le nqubo ibizwa ngokuthi ukunciphisa.

Isinqumo sokuyeka i-doxepin kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho, ngisho noma uzizwa ungcono. Ngokucindezeleka nokukhathazeka, ukuyeka ngokushesha kungaholela ekubuyeni kwezimpawu. Udokotela wakho uzokusiza ukuthi unqume isikhathi esifanele sokunciphisa noma ukuyeka umuthi wakho ngokusekelwe entuthukweni yakho nempilo yonke.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Doxepin?

Kungcono ukugwema utshwala ngenkathi uthatha i-doxepin, njengoba le nhlanganisela ingakhuphula ukozela futhi ilimaze ukuxhumana kwakho nokwahlulela kwakho. Utshwala bungaphazamisa nokusebenza komuthi futhi bungase lenze zibe zimbi izimpawu zokucindezeleka noma ukukhathazeka. Uma ukhetha ukuphuza ngezikhathi ezithile, xoxa ngalokhu nodokotela wakho kuqala.

Ngisho namanani amancane otshwala angaba nemiphumela eqinile uma ihlanganiswe ne-doxepin. Lokhu kubaluleke kakhulu uma uthatha umuthi wokulala, njengoba utshwala bungaphazamisa ikhwalithi yokulala futhi busebenzisane ngendlela eyingozi nemiphumela yokuthulisa ye-doxepin.