Yini i-Drospirenone ne-Estradiol: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Drospirenone ne-estradiol kuyinhlanganisela yokwelashwa ngamahomoni equkethe amahomoni amabili abesifazane asebenza ndawonye. Lo muthi oqokiwe uhlanganisa i-estradiol (uhlobo lwe-estrogen) ne-drospirenone (i-progestin yokwenziwa) ukusiza ukuphatha izimpawu ngesikhathi sokuya esikhathini esiphezulu kanye ne-perimenopause.

Abesifazane abaningi bathola ukuthi le nhlanganisela iyasiza ngoba ibhekana nezinkinga eziningi zokuya esikhathini esiphezulu ngesikhathi esisodwa. Ingxenye ye-estradiol isiza ukufaka esikhundleni se-estrogen umzimba wakho owenza ngaphansi ngesikhathi sokuya esikhathini esiphezulu, kuyilapho i-drospirenone inikeza ukusekelwa kwe-progestin ukuvikela umugqa wakho wesisu.

Isetshenziselwani i-Drospirenone ne-Estradiol?

Lo muthi uqala ukunqunywa ukwelapha ukushisa okulinganiselwe kuya kokukhulu kanye nokujuluka ebusuku kwabesifazane abase sebeqedile ukuya esikhathini. Uma uhlangabezana nalezi zimpawu ezingakhululeki eziphazamisa impilo yakho yansuku zonke noma ukulala, udokotela wakho angase acabange le ndlela yokwelapha kuwe.

Le nhlanganisela yenzelwe ngqo abesifazane abasenawo ummbila wabo. I-estradiol isiza ngezimpawu zokuya esikhathini esiphezulu njengokushisa, ukoma kwesitho sangasese sowesifazane, kanye nezinguquko zemizwa, kuyilapho i-drospirenone ivikela umugqa wakho wesisu ekukhuleni ngokweqile okungenzeka nge-estrogen yodwa.

Abanye odokotela baphinda banqume lo muthi ukusiza ukuvimbela i-osteoporosis kwabesifazane abase sebeqedile ukuya esikhathini esiphezulu abasengozini enkulu yokuphuka kwamathambo. Kodwa-ke, lokhu kuvame ukucatshangelwa kuphela uma ezinye izindlela zokwelapha i-osteoporosis zingakulungele.

Isebenza kanjani i-Drospirenone ne-Estradiol?

Lo muthi ohlanganisiwe usebenza ngokufaka esikhundleni sama-hormone umzimba wakho ngokwemvelo owenza ngaphansi ngesikhathi sokuya esikhathini esiphezulu. I-estradiol isebenza njenge-estrogen ama-ovari akho ayevame ukuyenza, isiza ukunciphisa ukushisa nezinye izimpawu zokuya esikhathini esiphezulu.

Ingxenye ye-drospirenone isebenza njenge-progestin yokwenziwa, elingisa i-hormone progesterone. Lokhu kubalulekile ngoba ukuthatha i-estrogen yodwa kungabangela ukuthi umugqa wesisu sakho ukhule ube mkhulu kakhulu, okungenzeka kuholele ezinkingeni zempilo.

Ngokubambisana, lawa mahomoni akha indlela elinganiselwe yokwelashwa kwe-hormone. I-estradiol ibhekana nezimpawu zakho zokuya esikhathini, kuyilapho i-drospirenone isiza ukulawula umjikelezo wakho wokuya esikhathini futhi ivikela impilo yakho yesibeletho.

Lokhu kuthathwa njengenketho yokwelashwa nge-hormone yamandla aphakathi nendawo. Inamandla kunezinye izindlela ezinamathiselwe ezitshalweni kodwa ngokuvamile ithambile kunezinhlanganisela ze-hormone eziphezulu.

Kufanele Ngiyithathe Kanjani I-Drospirenone ne-Estradiol?

Thatha lo muthi ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha ngaphandle noma ngaphandle kokudla, kodwa ukuyithatha nokudla kungasiza ukunciphisa noma yikuphi ukuphazamiseka kwesisu ongase ukuzwe.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayichobozi, uhlafune, noma uyiphule ithebhulethi, ngoba lokhu kungathinta indlela umuthi ogaywa ngayo emzimbeni wakho.

Zama ukuthatha umthamo wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga e-hormone aqhubekayo ohlelweni lwakho. Abesifazane abaningi bakuthola kuwusizo ukuxhumanisa ukuthatha imithi yabo emsebenzini wansuku zonke, njengokuxubha amazinyo abo noma ukudla kwasekuseni.

Uma ushintsha kwenye i-hormone therapy, udokotela wakho uzokunikeza imiyalelo ethile mayelana nesikhathi. Kungase kube negebe elifushane phakathi kokuyeka umuthi wakho omdala nokuqala lo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Drospirenone ne-Estradiol?

Ubude bokwelashwa buyahlukahluka kowesifazane ngamunye futhi kuncike ezimpawini zakho ngazinye nezidingo zempilo. Odokotela abaningi batusa ukusebenzisa i-hormone therapy isikhathi esifushane esidingekayo ukuze kulawulwe izimpawu zakho ngempumelelo.

Udktela wakho cishe uzofuna ukuhlola kabusha ukwelashwa kwakho njalo emavikini angu-3 kuya kwangu-6, ikakhulukazi ngonyaka wakho wokuqala. Lokhu kuhlolwa kusiza ukuqinisekisa ukuthi imithi isebenza kahle kuwe nokuthi awutholi imiphumela emibi ekhathazayo.

Abanye besifazane basebenzisa lo muthi iminyaka embalwa nje ukuze babhekane nezimpawu ezinzima kakhulu zokuya esikhathini. Abanye bangase badinge ukwelashwa isikhathi eside, ikakhulukazi uma besengozini enkulu yokuba ne-osteoporosis noma benezimpawu ezinzima ezinomthelela omkhulu ezingeni labo lempilo.

Ungayeki ukuthatha lo muthi kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ukwelashwa ngamahomoni kungazelelwe kungabangela ukuthi izimpawu zakho zokuya esikhathini zibuye ngokushesha futhi ngamandla.

Yini Imiphumela Emibi ye-Drospirenone ne-Estradiol?

Njengayo yonke imithi, i-drospirenone ne-estradiol ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi ezinyangeni ezimbalwa zokuqala.

Nawa amanye imiphumela emibi evame kakhulu ongase uyithole njengoba umzimba wakho ujwayela umuthi:

• Ukuqaqamba noma ukuvuvukala kwamabele
• Ikhanda elibuhlungu noma isiyezi esincane
• Isicanucanu noma ukuqaqamba kwesisu
• Ukuqunjelwa noma izinguquko ezincane zesisindo
• Ushintsho lwemizwa noma ukucasuka
• Ukuphuma kwegazi okungajwayelekile emithanjeni noma ukubona amachashaza

Lezi zimpawu zivame ukuncipha ngemva kwezinyanga ezi-2-3 zokusetshenziswa njalo. Uma ziqhubeka noma ziba zimbi, udokotela wakho angase alungise umthamo wakho noma ahlole ezinye izindlela zokwelapha.

Kukhona nemiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezokwelapha ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Ukuqaqamba okukhulu esifubeni noma ukuphefumula ngokushesha kungazelelwe
• Ikhanda elibuhlungu eliqinile kungazelelwe noma izinguquko embonweni
• Ukuqaqamba okukhulu emlenzeni noma ukuvuvukala emlenzeni owodwa
• Ukuqaqamba okukhulu esiswini
• Ukuphuzi kwesikhumba noma amehlo
• Ukuphuma kwegazi okungajwayelekile emithanjeni noma ukukhipha

Uma uba nezimpawu lezi, xhumana nodokotela wakho ngokushesha noma funa ukwelashwa okuphuthumayo.

Ubani Ongafanele Athathe i-Drospirenone ne-Estradiol?

Lo muthi awulungelwe wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwunika. Ezinye izimo zezempilo zenza ukwelashwa ngamahomoni kube yingozi kakhulu ukuthi kusetshenziswe ngokuphepha.

Akufanele uthathe lo muthi uma unezimo lezi zamanje noma ezedlule:

• Amaqhubu egazi emilenzeni yakho, emaphashini, noma kwezinye izindawo zomzimba wakho
• Isifo sesibindi esisebenzayo noma izimila zesibindi
• Ezinye izinhlobo zomdlavuza, ikakhulukazi umdlavuza webele noma we-endometrial
• Ukuphuma kwegazi okungachazeki emithanjeni
• Isifo sezinso esibi kakhulu
• Izinkinga ezinzima ze-adrenal gland

Udokotela wakho uzophinda aqaphele ngokunika lo muthi uma unesifo sikashukela, umfutho wegazi ophezulu, noma umlando wesifo senhliziyo. Lezi zimo azikuvimbeli ngokuzenzakalelayo ukusebenzisa ukwelashwa ngamahomoni, kodwa zidinga ukuqapha okuseduze.

Ubudala obunye okufanele bucatshangelwe. Lo muthi ngokuvamile awunconyelwe abesifazane abangaphezu kweminyaka engama-65 beqala ukwelashwa ngamahomoni okokuqala ngqa, njengoba izingozi zingase zidlule izinzuzo.

Amagama Omkhiqizo we-Drospirenone ne-Estradiol

Igama elivamile lomkhiqizo walo muthi ohlanganisiwe yi-Angeliq. Lona umkhiqizo ozohlangana nawo kakhulu ekhemisi lakho lapho udokotela wakho ekunika i-drospirenone ne-estradiol.

Izinhlobo ezivamile zokuhlanganiswa kwalo muthi nazo ziyatholakala futhi ziqukethe izithako ezifanayo ezisebenzayo njengenguqulo yegama lomkhiqizo. Umuthi wakho wezemithi angakusiza ukuthi uqonde ukuthi ngabe uthola inguqulo yegama lomkhiqizo noma ejwayelekile.

Zombili izinhlobo zegama lomkhiqizo nezivamile zisebenza ngendlela efanayo. Ukukhetha kuvame ukwehla ekuhlinzekweni komshuwalense wakho kanye nokukhetha komuntu siqu, ongaxoxa ngakho nodokotela wakho nomuthi wakho.

Ezinye izindlela ze-Drospirenone ne-Estradiol

Uma le mithi ingakulungele, ezinye izindlela ezingasiza ekuphatheni izimpawu zokuya esikhathini. Udokotela wakho angase ancome ezinye izinhlanganisela zokwelapha ngamahomoni ezisebenzisa izinhlobo ezahlukene zama-progestin noma ama-estrogen.

Abanye besifazane benza kahle ngama-patch, ama-gel, noma ama-cream e-estrogen kuphela, ikakhulukazi uma behlinzwe i-hysterectomy. Lezi zinketho zingaba lula esiswini sakho futhi zinikeze umthamo oguquguqukayo.

Ezinye izindlela ezingahlobene nama-hormone zihlanganisa ama-antidepressants athile, imithi yokwehlisa umfutho wegazi, kanye nemithi yokulwa nokuthuthumela engasiza ekunciphiseni ukushisa. Lezi zinketho ziwusizo ikakhulukazi kwabesifazane abangakwazi ukusebenzisa ukwelashwa ngamahomoni ngenxa yezinkinga zempilo.

Izindlela zemvelo nezokuphila nazo zingahlinzeka ngokuphumula. Ukuzivivinya njalo, izindlela zokuphatha ingcindezi, izinguquko ekudleni, kanye nezinye izithasiselo zingasiza ekunciphiseni izimpawu zokuya esikhathini, nakuba ngokuvamile zingasebenzi kangako kunokwelashwa ngamahomoni ezimpawu ezinzima.

Ingabe i-Drospirenone ne-Estradiol Ingcono Kunezinye Izindlela Zokwelapha Ngamahomoni?

Ukuthi le nhlanganisela ingcono kunezinye izindlela zokwelapha ngamahomoni kuncike ngokuphelele ezidingweni zakho zomuntu ngamunye kanye nephrofayili yezempilo. Inketho ngayinye yokwelashwa ngamahomoni inezinzuzo ezihlukile kanye nezinto okufanele zicatshangelwe.

Uma kuqhathaniswa nezinye izindlela zokwelapha ngamahomoni, i-drospirenone ne-estradiol ingase ibangele ukuqunjelwa okuncane nokukhuluphala. Ingxenye ye-drospirenone inezakhiwo ezithambile ze-diuretic, ezingasiza ekunciphiseni ukugcinwa kwamanzi abanye besifazane abahlangabezana nakho ngamanye ama-progestin.

Nokho, i-drospirenone ingase ikhuphule kancane ingozi yama-clot egazi uma iqhathaniswa namanye ama-progestin. Lokhu akusho ukuthi kuyingozi kwabesifazane abaningi, kodwa kuyinto udokotela wakho azoyicabangela lapho ekhetha inketho engcono kakhulu kuwe.

Ukwelashwa ngamahomoni

Imibuzo Evame Ukubuzwa Mayelana ne-Drospirenone kanye ne-Estradiol

Ingabe i-Drospirenone kanye ne-Estradiol iphephile kwabesifazane abanomfutho wegazi ophezulu?

Abesifazane abanomfutho wegazi ophezulu olawulwa kahle bangavame ukusebenzisa lo muthi ngokuphepha ngokuqapha ngokucophelela. Udokotela wakho uzofuna ukuhlola umfutho wegazi lakho njalo, ikakhulu ezinyangeni ezimbalwa zokuqala zokwelashwa.

Ingxenye ye-drospirenone ngezinye izikhathi ingabangela ukwanda okuncane kwamazinga e-potassium, okungavamile ukuba yinkinga kwabesifazane abaningi. Kodwa-ke, uma uthatha imithi ethile yomfutho wegazi noma unezinkinga zezinso, udokotela wakho angase aqaphele amazinga akho e-potassium ngokusondela.

Uma umfutho wegazi lakho ungalawulwa kahle, udokotela wakho cishe uzofuna ukuwuzinzisa ngaphambi kokuqala ukwelashwa ngamahomoni. Lokhu kuqinisekisa ukuthi uthola ukwelashwa okuphephe kunakho konke.

Ngingenzani uma ngiphuthelwa ngengozi ukuthatha i-Drospirenone kanye ne-Estradiol eningi kakhulu?

Uma ngengozi uthatha umthamo owengeziwe, ungesabi. Ukuthatha ithebhulethi eyodwa eyengeziwe akunakwenzeka ukuthi kubangele izinkinga ezinkulu, kodwa ungase uhlangabezane nokwanda kwesicanucanu, ukuba bucayi kwamabele, noma ukuphuma kwegazi okungajwayelekile.

Xhumana nodokotela wakho noma usokhemisi ukuze uthole isiqondiso sokuthi wenzeni ngokulandelayo. Bangase batusa ukweqa umthamo wakho olandelayo noma uqhubeke neshejuli yakho ejwayelekile, kuye ngokuthi ukweqisa kwenzeke nini.

Uma uthathe amathebhulethi amaningi engeziwe noma uhlangabezana nezimpawu ezinzima njengesicanucanu esinamandla, ukuhlanza, noma ukuphuma kwegazi okungajwayelekile, funa ukunakekelwa kwezokwelapha ngokushesha. Gcina ibhodlela lomuthi nawe ukuze ubonise abahlinzeki bezempilo ukuthi uthathe ini nokuthi kungakanani.

Ngingenzani uma ngiphuthelwa umthamo we-Drospirenone kanye ne-Estradiol?

Uma uphuthelwa umthamo futhi ukhumbula kungakapheli amahora angu-12, thatha ngokushesha lapho ukhumbula. Bese uqhubeka neshejuli yakho ejwayelekile ngosuku olulandelayo.

Uma amahora angaphezu kwayi-12 edlule ngemuva komthamo wakho ongekho, weqa bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ongekho, ngoba lokhu kungakhuphula ingozi yakho yemiphumela engemihle.

Ukuphuthelwa imithamo ngezikhathi ezithile ngeke kukulimaze, kodwa zama ukugcina ukuqina ukuze uthole ukulawulwa okungcono kakhulu kwezimpawu. Cabangela ukusetha isikhumbuzi sansuku zonke ocingweni lwakho noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule.

Ngingayeka nini ukuthatha i-Drospirenone ne-Estradiol?

Isinqumo sokuyeka ukwelashwa ngamahomoni kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho. Abesifazane abaningi banganciphisa kancane kancane umthamo wabo ezinyangeni eziningana kunokuyeka kungazelelwe.

Udokotela wakho angase asikisele ukuyeka uma izimpawu zakho zokuya esikhathini zithuthuke kakhulu, uma uthola izimo zezempilo ezenza ukwelashwa ngamahomoni kube yingozi, noma uma uhlangabezana nemiphumela engemihle ekhathazayo engathuthuki.

Abanye besifazane bakhetha ukuyeka ngemuva kweminyaka embalwa yokwelashwa, kanti abanye baqhubeka isikhathi eside uma izinzuzo zidlula izingozi. Ukuhlolwa njalo nodokotela wakho kusiza ukuqinisekisa ukuthi wenza isinqumo esingcono kakhulu sesimo sakho sempilo yamanje.

Ngingayithatha i-Drospirenone ne-Estradiol uma ngihlela ukuhlinzwa?

Ngokuvamile uzodinga ukuyeka lo muthi amasonto angu-4-6 ngaphambi kwanoma yikuphi ukuhlinzwa okukhulu, ikakhulukazi izinqubo ezidinga i-anesthesia ejwayelekile noma ezihilela izikhathi ezinde zokunganyakazi. Ukwelashwa ngamahomoni kungakhuphula kancane ingozi yamaqhubu egazi ngesikhathi nangemva kokuhlinzwa.

Njalo yazisa udokotela ohlinzayo kanye nodokotela we-anesthesiologist ngayo yonke imithi oyithathayo, okuhlanganisa nokwelashwa ngamahomoni. Bazokunikeza imiyalelo ethile mayelana nokuthi uyeka nini nokuthi kuphephile nini ukuqala kabusha ngemuva kwenqubo yakho.

Ngezinqubo ezincane zokuhlinzwa kwabantu abangaguli, ungase ungadingeki ukuyeka umuthi nhlobo. Ithimba lakho lezempilo lizokwenza lesi sinqumo ngokusekelwe ohlotsheni lokuhlinzwa kanye nezici zakho eziyingozi.