Eculizumab-aagh (indlela ye-intravenous)

Akukho luhlu olutholakalayo lweziqondiso ze-Epysqli ngesiZulu.

I-Eculizumab-aagh injection isetyenziselwa ukwelapha uhlobo lwesifo segazi oluthiwa yi-paroxysmal nocturnal hemoglobinuria (PNH). Le mishini iyanciphisa ukuwohloka kwamaseli egazi ebomvu noma ukuwohloka (hemolysis) kubantu abane-PNH. Le mishini isetshenziswa futhi ekwelapheni isifo esibi sesiqiniso sokuthiwa yi-atypical hemolytic uremic syndrome (aHUS). I-Eculizumab-aagh injection iyilona i-antibody elihlukanisiwe eliqondene nesistimu yokulwa nezifo. Le mishini itholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthiwa yi-EPYSQLI® REMS (Uhlelo Lokuhlola Ubungozi Nokunciphisa).

Umakuqondisa ekusebenziseni imithi, kufanele kuqhathaniswe ingozi yokuthatha imithi nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqhelile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela yokubeka i-eculizumab-aagh ukuze kuphathwe i-PNH kubantwana. Ukuphepha nokuphumelela akukamiswanga. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantwana ezingalinda ukusetshenziswa kwe-eculizumab-aagh injection ukuze kuphathwe i-aHUS kubantwana. Ukuphepha nokuphumelela kuye kwaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-eculizumab-aagh injection kubantu abadala. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthola le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshako nanoma iyiphi imithi kungase futhi kubangele ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshako. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi: