Yini i-Ethionamide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Ethionamide iyisidakamizwa esikhethekile se-antibiotic esilwa namagciwane e-tuberculosis (TB) lapho ukwelashwa okujwayelekile kungasebenzi ngempumelelo. Lo muthi ungoweqembu elibizwa ngokuthi izidakamizwa ze-anti-TB zomugqa wesibili, okusho ukuthi odokotela bavame ukuwuncoma lapho imithi yokuqala ingakwazi ukususa lesi sifo ngokuphelele. Nakuba kungewona umuthi omnene ongawuthatha, i-ethionamide idlala indima ebalulekile ekwelapheni i-tuberculosis engamelani nemithi futhi isize abantu ukuthi balulame kulolu hlobo olukhulu lokutheleleka emaphashini.

Yini i-Ethionamide?

I-Ethionamide iyi-antibiotic yomlomo eyenzelwe ngqo ukubulala amagciwane e-tuberculosis asemelana nemithi ejwayelekile ye-TB. Cabanga ngayo njengesikhali esiyisipele empini yokulwa ne-TB lapho ama-antibiotics ajwayelekile engakwazi ukufeza umsebenzi. Lo muthi usebenza ngokuphazamisa ikhono lamagciwane e-TB lokwakha izindonga zawo zamaseli, ngokuwenza buthaka aze afe.

Lo muthi uza ngesimo samaphilisi futhi ngokuvamile uyingxenye yohlelo lokwelapha oluhlanganisiwe. Udokotela wakho cishe uzohlala encoma i-ethionamide kanye neminye imithi ye-anti-TB ngoba ukusebenzisa imithi eminingi ndawonye kusebenza kahle kakhulu kunokuncika emthini owodwa nje. Le ndlela futhi isiza ekuvikeleni amagciwane ekuthuthukiseni ukumelana okwengeziwe.

Isetshenziselwani i-Ethionamide?

I-Ethionamide isetshenziswa ikakhulukazi ukwelapha i-tuberculosis engamelani nemithi, ikakhulukazi lapho amagciwane e-TB engasabeli emithini yomugqa wokuqala efana ne-isoniazid noma i-rifampin. Udokotela wakho angase ancome lo muthi uma izivivinyo zaselabhorethri zikhombisa ukuthi uhlobo lwakho lwe-TB lumelana nokwelashwa okujwayelekile, noma uma usuvele uzamile eminye imithi ye-TB ngaphandle kwempumelelo.

Lo muthi ngezinye izikhathi usetshenziselwa ukwelapha izifo ze-mycobacterial ezingajwayelekile, ezibangelwa amagciwane afana ne-TB kodwa angafani ngokuphelele. Lezi zifo zingathinta amaphaphu akho, ama-lymph nodes, noma ezinye izindawo zomzimba wakho. Nokho, i-ethionamide ayisetshenziselwa izifo zamagciwane ezivamile njenge-pneumonia noma izifo zomgudu womchamo.

Ezimweni ezingavamile, odokotela bangase banikeze i-ethionamide njengengxenye yokwelashwa kokuvimbela uma uke wavezwa ku-TB engamelani nemithi futhi usengozini enkulu yokuthuthukisa lesi sifo. Lokhu kuvame ukwenzeka emndenini osondelene noma abasebenzi bezempilo abaye bahlangana kakhulu nomuntu one-TB esebenzayo, engamelani nemithi.

Isebenza Kanjani I-Ethionamide?

I-Ethionamide isebenza ngokugxila kunqubo ethile edingwa amagciwane e-TB ukuze asinde futhi azale. Lo muthi uphazamisa ikhono lamagciwane lokukhiqiza ama-mycolic acids, okuyizakhi ezibalulekile zezindonga zawo zamaseli. Ngaphandle kwalezi zindonga zamaseli ezivikelayo, amagciwane aba sengozini futhi ekugcineni afe.

Lokhu kuthathwa njengomuthi onamandla ngokulinganisela mayelana nokusebenza kwawo ngokuqeda amagciwane e-TB. Nakuba inganamandla njengeminye imithi ye-TB yomugqa wokuqala, i-ethionamide ingasebenza kahle uma isetshenziswa njengengxenye yohlelo lokwelashwa olubanzi. Okubalulekile ukuthi ihlasela amagciwane ngendlela ehlukile kuneminye imithi ye-TB, okwenza ibe yigugu ezinhlotsheni ezingamelanayo.

Lo muthi udinga isikhathi sokwakheka emzimbeni wakho bese uqala ukusebenza ngempumelelo. Ngokuvamile ngeke uzizwe ngcono ngokushesha, futhi kungase kuthathe amasonto amaningana noma izinyanga ngisho nokubona izinguquko ezinkulu ezimpawini zakho. Lokhu kuvamile ngokuphelele ekwelashweni kwe-TB, njengoba la magciwane enenkani futhi kuthatha isikhathi ukuwaqeda.

Kufanele Ngiyithathe Kanjani I-Ethionamide?

Thatha i-ethionamide ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye noma kabili ngosuku ngokudla noma ubisi. Ukuyithatha ngokudla kubalulekile ngoba lo muthi ungaba nzima esiswini sakho, futhi ukudla ngaphambi kokuthatha usizo lokunciphisa isicanucanu nokungakhululeki kwesisu. Abantu abaningi bathola ukuthi ukuyithatha ngokudla kwabo okukhulu kosuku kusebenza kahle kakhulu.

Ungayithatha i-ethionamide ngobisi, iyogathi, noma ukudla okulula uma ukhetha. Abanye abantu bathola ukuthi ukuba nesnakhi esincane njengama-crackers noma isinkwa esosiwe ngaphambi kokuthatha umuthi kusiza ekuvikeleni ukungakhululeki kwesisu. Gwema ukuyithatha esiswini esingenalutho, ngoba lokhu kwandisa kakhulu ithuba lokuba nesicanucanu nokuhlanza.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo omuthi egazini lakho. Uma unikezwe umthamo kabili ngosuku, hlukanisa imithamo ngamahora angaba ngu-12. Ukusetha i-alamu yansuku zonke kungakusiza ukuthi ukhumbule, ikakhulukazi njengoba ukwelashwa kwe-TB kudinga ukunamathela okuqinile ukuze kusebenze.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ungawachobozi, uwahlafune, noma uwaphule amaphilisi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze njalo. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinye izindlela noma amasu angasiza.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Ethionamide?

Abantu abaningi bathatha i-ethionamide izinyanga eziyi-12 kuya kwezingama-24 njengengxenye yokwelashwa kwabo umkhuhlane wamaphaphu, nakuba abanye bengase bayidinge izikhathi ezimfushane noma ezinde kuye ngesimo sabo esithile. Udokotela wakho uzoqoka isikhathi esiqondile esisekelwe ezintweni ezinjengokuthi uphendula kahle kangakanani ekwelashweni, ukuthi i-TB yakho imelana nemithi yini, nemiphumela evela ezivivinyweni zakho zokubheka njalo.

Ubude bokwelashwa bungase bubonakale bunzima, kodwa kubalulekile ukuthatha imithi isikhathi esiphelele esinqunyiwe ngisho noma uqala ukuzizwa ungcono. Amagciwane e-TB aqinile kakhulu, futhi ukuyeka ukwelashwa ngaphambi kwesikhathi kungaholela ekutheni lesi sifo sibuye sibe namandla futhi simelane kakhulu kunakuqala. Lokhu kungenza ukwelashwa okuzayo kube nzima kakhulu.

Udokotela wakho uzoqapha inqubekela phambili yakho ngokuhlolwa njalo, izivivinyo ze-sputum, kanye nemisebe ye-X yesifuba. Lezi zivivinyo zisiza ukunquma ukuthi imithi isebenza kahle kangakanani nokuthi ngabe udinga ukuqhubeka nokwelashwa. Kwezinye izimo, udokotela wakho angase alungise ubude ngokuya ngokuthi umzimba wakho ususa ngokushesha kangakanani lesi sifo.

Kubantu abane-TB engathí sina kakhulu noma esanda kutholakala engamelani nemithi, ukwelashwa kungase kube ngesikhathi esifushane salolu hlu. Kodwa-ke, labo abanesifo esikhulu noma ukumelana nemithi eminingi bangase badinge izifundo zokwelashwa ezinde. Ithimba lakho lezempilo lizosebenza nawe ukudala uhlelo lokwelashwa olwenzelwe wena olukunika ithuba elingcono kakhulu lokululama ngokuphelele.

Yiziphi Izimo Ezingezinhle Zokusebenzisa i-Ethionamide?

Njengemithi eminingi ye-TB, i-ethionamide ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela emibi evame kakhulu ithinta uhlelo lwakho lokugaya ukudla futhi ihlanganisa isicanucanu, ukuhlanza, ubuhlungu besisu, nokulahlekelwa isifiso sokudla. Lezi zimpawu zivame ukubonakala kakhulu lapho uqala ukuthatha imithi futhi ngokuvamile zithuthuka njengoba umzimba wakho uzivumela.

Nawa amanye imiphumela emibi ongase uyithole:

• Isicanucanu nokuhlanza, ikakhulukazi emasontweni ambalwa okuqala
• Ukulahlekelwa isifiso sokudla nokuncipha kwesisindo
• Ubuhlungu besisu noma ukungakhululeki esiswini
• Ukunambitheka kwensimbi emlonyeni wakho
• Ukuqunjelwa noma izitulo ezixekile
• Ukukhathala nobuthakathaka obujwayelekile
• Ikhanda
• Isiyezi noma ukuzwa sengathi uyakhathala

Lezi zimpawu zokugaya ukudla zivame ukulawuleka ngamasu alula afana nokuthatha imithi nokudla, ukudla ukudla okuncane okuvame kakhulu, nokuhlala unamanzi kahle. Abantu abaningi bathola ukuthi le miphumela emibi iba ngaphansi kokuphazamisa ngemva kwenyanga yokuqala yokwelashwa.

Abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Izinkinga ezinzima zesibindi, ezingase zibangele ukuphuzi kwesikhumba noma amehlo, umchamo omnyama, noma isicanucanu esiqhubekayo
• Izinkinga zemizwa (i-peripheral neuropathy) ebangela ukuba ndikindiki, ukuluma, noma ubuhlungu ezandleni nasezinyaweni
• Ushintsho lwempilo yengqondo oluhlanganisa ukucindezeleka, ukudideka, noma ukushintsha kwemizwa
• Ukungezwani komzimba okukhulu okunezinduna, ukuluma, noma ubunzima bokuphefumula
• Izinkinga ze-thyroid, ezingase zibangele izinguquko emazingeni amandla noma isisindo
• Ushintsho embonweni noma izinkinga zamehlo
• Ukuphalaza okuqhubekayo okukuvimbela ukuthi ungagcini ukudla noma uketshezi

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína, xhumana nodokotela wakho ngokushesha. Ithimba lakho lezempilo lizokuhlola njalo ngezivivinyo zegazi ukuze libambe izinkinga ezingaba khona ekuqaleni, ngokuvamile ngaphambi kokuba uqaphele noma yiziphi izimpawu.

Ezimweni ezingavamile, i-ethionamide ingabangela imiphumela emibi engavamile efana nokulahlekelwa izinwele, ubuhlungu emalungeni, noma izinguquko emazingeni kashukela wegazi. Abanye abantu futhi babika ukwanda kokuzwela elangeni, ngakho ukusebenzisa i-sunscreen kuba okubaluleke kakhulu ngesikhathi sokwelashwa.

Ubani Ongafanele Athatha I-Ethionamide?

I-Ethionamide ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzocabangela ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abanezifo zesibindi ezinzima ngokuvamile kufanele bagweme lo muthi ngoba ungafaka ingcindezi eyengeziwe esibindini futhi kungenzeka ubangele izinkingo eziyingozi.

Akufanele usebenzise i-ethionamide uma uke waba nokusabela okukhulu komzimba okuyingozi kuyo noma imithi efanayo esikhathini esidlule. Lokhu kuhlanganisa ukusabela okufana nobunzima bokuphefumula, ukuqubuka okukhulu, noma ukuvuvukala kobuso, izindebe, ulimi, noma umphimbo. Noma ngabe uke waba nokusabela okuncane komzimba ngaphambilini, qiniseka ukuthi uxoxa ngalokhu nodokotela wakho.

Nawa amanye amazinga lapho i-ethionamide ingase ingafaneleki khona:

• Isifo esibi sezinso noma ukwehluleka kwezinso
• Isifo sesibindi esisebenzayo noma ama-enzyme esibindi aphakeme kakhulu
• Izinkinga zenhliziyo ezinzima noma iziyaluyalu zesigqi senhliziyo ezingalawuleki
• Umlando wezinkinga ezinkulu zempilo yengqondo eziye zaba zimbi ngemithi efanayo
• Izifo ze-thyroid ezinzima ezingalawulwa kahle
• Ukukhulelwa, ikakhulukazi ngesikhathi sokukhulelwa kokuqala
• Isifo sikashukela esibi okunzima ukusilawula

Uma unanoma yiziphi zalezi zimo, ungakhathazeki - udokotela wakho uzosebenza nawe ukuthola ezinye izindlela zokwelapha eziphephe kakhulu esimweni sakho esithile. Ngezinye izikhathi izinzuzo zokwelapha i-TB engamelani nemithi zidlula izingozi ezingaba khona, kodwa lesi sinqumo kufanele senziwe ngokucophelela nethimba lakho lezempilo.

Imithi ethile ingase isebenzisane ne-ethionamide, ngakho qiniseka ukuthi udokotela wakho uyazi ngayo yonke imithi oyithathayo. Lokhu kuhlanganisa imithi kadokotela, imithi etholakala ngaphandle kwemvume kadokotela, amavithamini, kanye nezithasiselo zemithi yezitshalo. Eminye imithi yesifo sikashukela, ama-blood thinners, kanye nemithi yezifo zengqondo kungase kudingeke ukuthi kulungiswe umthamo uma ithathwa ne-ethionamide.

Amagama Omkhiqizo we-Ethionamide

I-Ethionamide iyatholakala ngaphansi kwegama lomkhiqizo elithi Trecator e-United States. Lolu uhlobo oluvame kakhulu olubhalwe ngemithi emakhemisi aseMelika. Inguqulo ejwayelekile nayo iyatholakala futhi isebenza ngendlela efanayo nenguqulo yegama lomkhiqizo.

Emazweni angaphandle, i-ethionamide ingase ithengiswe ngaphansi kwamagama ahlukene emakethe, kodwa isithako esisebenzayo sihlala singashintshi. Umuthi wakho wemithi angakusiza ukuthi ubone ukuthi uthola yini igama lomkhiqizo noma inguqulo ejwayelekile yomuthi. Zombili lezi zinhlobo zisebenza ngokulinganayo ekwelapheni isifo sofuba.

Ezinye izinkampani zemithi zingase zihlanganise i-ethionamide neminye imithi yesifo sofuba, nakuba lokhu kungavamile. Udokotela wakho uzochaza ngqo ukuthi yiluphi uhlobo namandla e-ethionamide owadingayo ngokusekelwe ohlelweni lwakho lokwelashwa.

Ezinye izindlela ze-Ethionamide

Uma i-ethionamide ingakulungele noma ibangela imiphumela engathandeki, ezinye izindlela zemithi yesifo sofuba yesibili zingase zisebenze esikhundleni sayo. Udokotela wakho angase acabangele i-cycloserine, esebenza ngendlela ehlukile kodwa futhi isebenza kahle emabhaktheriya e-TB amelana nemithi. Kodwa-ke, i-cycloserine ingabangela imiphumela ehlukene, ikakhulukazi ethinta isimiso sezinzwa.

Ezinye izindlela zihlanganisa i-para-aminosalicylic acid (PAS), evame ukuba mnene esiswini kodwa idinga ukuthatha amaphilisi amaningi amakhulu nsuku zonke. Ama-antibiotics e-Fluoroquinolone afana ne-levofloxacin noma i-moxifloxacin nawo asebenza kahle ku-TB futhi avame ukubekezelelwa kangcono kune-ethionamide.

Imithi emisha efana ne-bedaquiline ne-delamanid iyatholakala ezinhlotsheni ezithile ze-TB ezimelana nemithi, nakuba lezi zivame ukugcinelwa amacala anzima kakhulu. Udokotela wakho uzocabangela izinto ezinjengohlobo lwakho oluthile lwe-TB, ezinye izimo zempilo, kanye nezimpendulo zokwelashwa zangaphambilini lapho ekhetha ezinye izindlela.

Ukukhethwa komuthi ozongena esikhundleni kuncike kakhulu ekuhlolweni kwelebhu okukhombisa ukuthi yimiphi imithi amabhaktheriya akho e-TB athambekele kuyo. Yingakho kubaluleke kakhulu ukuqeda konke ukuhlolwa okuhlelwe udokotela wakho, ngisho noma kuthatha isikhathi ukuthola imiphumela.

Ingabe i-Ethionamide ingcono kunezinye izindlela zokwelapha i-TB?

I-Ethionamide akudingeki ukuthi "ingcono" kunezinye izidakamizwa ze-TB - imane nje yehluke futhi inenjongo ethile ekwelapheni i-tuberculosis engamelani nemithi. Imithi ye-TB yomugqa wokuqala efana ne-isoniazid ne-rifampin ngokuvamile isebenza kahle futhi ibekezeleleka kangcono uma isebenza ngokuphikisana nohlobo lwakho oluthile lwe-TB.

Inzuzo ye-ethionamide ukuthi ingalwa namagciwane e-TB asemelana nemithi ejwayelekile. Kulezi zimo, i-ethionamide ingase ibe inketho yakho engcono nakuba ingase ibangele imiphumela eminingi kunemithi yomugqa wokuqala. Cabanga ngayo njengethuluzi elikhethekile lomsebenzi othile kunokuba kube umuthi ongcono emhlabeni wonke.

Uma iqhathaniswa neminye imithi ye-TB yomugqa wesibili, i-ethionamide inezinzuzo nobubi. Ivame ukusebenza ngempumelelo kunezinye izindlela kodwa ingase ibangele izinkinga ezingaphezulu zesisu. Umuthi "ongcono" kuwe uncike esimweni sakho esithile, okuhlanganisa ukuthi unaluphi uhlobo lwe-TB, ezinye izimo zakho zempilo, nokuthi uyibekezelela kangakanani imithi ehlukene.

Udokotela wakho uzokhetha i-ethionamide ngokusekelwe ekuhlolweni kwelabhorethri okukhombisa ukuthi kungenzeka isebenze ngokuphikisana namagciwane akho athile e-TB. Le ndlela yomuntu siqu ikunikeza ithuba elingcono lokususa ukutheleleka ngenkathi kunciphisa imiphumela engadingekile.

Imibuzo Evame Ukubuzwa Mayelana ne-Ethionamide

Q1. Ingabe i-Ethionamide iphephile Kwabesifazane Abakhulelwe?

I-Ethionamide ngokuvamile ayinconyelwe ngesikhathi sokukhulelwa, ikakhulukazi ku-trimester yokuqala, ngoba ingase ibangele ukukhubazeka kokuzalwa. Uma ukhulelwe noma uhlela ukukhulelwa ngenkathi uthatha lo muthi, khuluma nodokotela wakho ngokushesha mayelana nezinye izindlela eziphephile zokwelapha i-TB yakho.

Kodwa-ke, ezimweni ezingavamile lapho owesifazane okhulelwe enesifo somdlavuza esingelapheki esibucayi futhi ezinye izindlela eziphephile zingasebenzi, odokotela bangase bacabange ukusebenzisa i-ethionamide ngesikhathi sesibili noma sesithathu sokukhulelwa. Lesi sinqumo singenziwa kuphela uma izinzuzo zicacile ukuthi zidlula izingozi ezingaba khona kumama nomntwana.

Uma ukhulelwa ngenkathi uthatha i-ethionamide, ungayeki imithi ngokuphazima kweso ngaphandle kokubonisana nodokotela wakho. I-TB engelashwa nayo ingaba yingozi ngesikhathi sokukhulelwa, ngakho-ke ithimba lakho lezempilo lizodinga ukuhlela ngokucophelela noma yiziphi izinguquko zemithi ukuze likugcine wena nomntwana wakho niphephile.

Umbuzo 2. Kufanele ngenzeni uma ngisebenzisa i-Ethionamide eningi ngengozi?

Uma ngengozi uthatha i-ethionamide eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ikakhulukazi uma uhlangabezana nesicanucanu esibi, ukuhlanza, ukudideka, noma ubunzima bokuphefumula. Ukuthatha okuningi kakhulu kunokunqunyiwe kungakhuphula ingozi yakho yemiphumela emibi, ikakhulukazi izinkinga zesibindi nemiphumela yezinzwa.

Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ukwenza kanjalo ngumhlinzeki wezempilo. Kunalokho, zama ukuhlala uzolile futhi ufune isiqondiso sezokwelapha ngokushesha. Yiba nebhodlela lakho lemithi nawe lapho ushayela ucingo ukuze unikeze imininingwane eqondile mayelana nokuthi uthathe malini nokuthi nini.

Uma uzizwa ungaphilile kakhulu ngemuva kokuthatha imithi eningi, unganqikazi ukuya egumbini eliphuthumayo. Letha ibhodlela lakho lemithi kanye nanoma yimiphi eminye imithi oyithathayo ukuze ithimba lezokwelapha linikeze ukunakekelwa okufanele.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Ethionamide?

Uma uphuthelwa umthamo we-ethionamide, uyithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi.

Zama ukuthatha umthamo owuphuthelwe kungakapheli amahora ambalwa ngesikhathi obuvamise ukuthatha ngaso. Uma uthatha i-ethionamide kabili ngosuku futhi uphuthelwa umthamo wakho wasekuseni, ungawuthatha ngesidlo sasemini esikhundleni sokulinda kuze kube umthamo wakho wakusihlwa. Vele uqinisekise ukuthi uhlukanisa imithamo yakho ngendlela efanele.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha ama-alamu ansuku zonke noma usebenzise umhleli wamaphilisi ukukusiza ukhumbule. Ukunamathela ngokuqhubekayo emithini kubalulekile empumelelweni yokwelashwa kwe-TB, ngakho-ke ukuthuthukisa inqubo ekusebenzelayo kubalulekile ekululameni kwakho.

Q4. Ngingayeka nini ukuthatha i-Ethionamide?

Kufanele uyeke kuphela ukuthatha i-ethionamide lapho udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo, okwenzeka ngokujwayelekile ngemuva kokuqeda inkambo yakho ephelele yokwelashwa. Lesi sinqumo sisekelwe ezintweni eziningi ezihlanganisa izimpawu zakho, imiphumela yokuhlolwa kwelabhorethri, kanye nezifundo zokuthwebula izithombe ezikhombisa ukuthi i-TB yakho isusiwe ngokuphelele.

Noma ngabe uzizwa ungcono ngokuphelele, ungayeki ukuthatha i-ethionamide ngaphambi kwesikhathi. Amagciwane e-TB angasinda emzimbeni wakho ngisho nalapho uzizwa kahle, futhi ukuyeka ukwelashwa ngaphambi kwesikhathi kungaholela ekutheni lesi sifo sibuye ngesimo esinokumelana kakhulu. Lokhu kungenza ukwelashwa okuzayo kube nzima kakhulu futhi kube kude.

Udokotela wakho uzoqapha inqubekela phambili yakho ngokuhlolwa okuvamile kanye nokuhlolwa ngesikhathi sokwelashwa kwakho. Lokhu kuqokwa kubalulekile ekunqumeni ukuthi kuphephile nini ukuyeka imithi yakho. Uma ukhathazekile ngemiphumela emibi noma ufuna ukuxoxa ngomugqa wakho wesikhathi sokwelashwa, lezi zinkathazo ziveze ngesikhathi sokuvakasha kwakho okuvamile.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Ethionamide?

Kungcono ukugwema utshwala ngokuphelele ngenkathi uthatha i-ethionamide, njengoba womabili umuthi notshwala kungacindezela isibindi sakho. Njengoba i-ethionamide isivele inengozi yezinkinga zesibindi, ukwengeza utshwala emxube kwandisa kakhulu amathuba akho okuthuthukisa izinkinga zesibindi ezinzima.

Utywala bungenza buqine imiphumela eminingi eseceleni ye-ethionamide, ikakhulukazi isicanucanu, ukuhlanza, nokuphazamiseka kwesisu. Ngisho namanani amancane otshwala angase akuqede amandla kunokujwayelekile ngenkathi uthatha lo muthi. Ngaphezu kwalokho, utshwala bungaphazamisa ikhono lomzimba wakho lokulwa nesifo se-TB.

Uma ukhathazekile ngokusebenzisa utshwala noma ukuthola kunzima ukugwema ukuphuza ngesikhathi sokwelashwa kwe-TB, khuluma nodokotela wakho mayelana nezinsiza ezingasiza. Ithimba lakho lokunakekelwa kwezempilo lifuna ukukusekela ngazo zonke izindlela ezingenzeka ukuqinisekisa ukuthi ukwelashwa kwakho kuyaphumelela futhi ululama ngokugcwele esifweni somdlavuza.