Yini i-Etidronate: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Etidronate iyikhambi eliqinisa amathambo elisiza ukuvimbela amathambo akho ukuthi angabhidliki ngokushesha kakhulu. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-bisphosphonates, asebenza njengezihlangu ezivikelayo zamathambo akho ngokunciphisa inqubo yemvelo ewaqeda ngokuqhubeka kwesikhathi.

Le mithi isisize abantu ukuthi bagcine amathambo aqinile amashumi eminyaka. Udokotela wakho angase ayincomise uma unezimo ezithile zamathambo noma uma usengozini yokuthuthukisa amathambo abuthakathaka angaphuka kalula.

Yini i-Etidronate Esetshenziselwa Yona?

I-Etidronate iphatha futhi ivimbele izimo eziningana ezihlobene namathambo lapho amathambo akho eba buthakathaka noma ebhidlika ngokushesha kunokuba kufanele. Isizathu esivame kakhulu sokuthi odokotela banikeze le mithi ukusiza abantu abanesifo sikaPaget, isimo lapho amathambo ekhula ngokungavamile futhi abe mabi.

Udokotela wakho angase futhi ancome i-etidronate uma une-osteoporosis, ikakhulukazi uma ibangelwa ukusetshenziswa kwama-steroid isikhathi eside. Abanye abantu bayayithatha ukuvimbela ukulahleka kwamathambo ngemva kokwelashwa okuthile kwezokwelapha noma ukuhlinzwa okungase kuqede amathambo.

Ngokuvamile, odokotela banikeza i-etidronate kubantu abathuthukisa amadiphozi e-calcium engeziwe ezicutshini zabo ezithambile, isimo esibizwa ngokuthi i-heterotopic ossification. Lokhu kungenzeka ngemva kokuhlinzwa kokufakelwa okhalweni noma ukulimala komgogodla.

Isebenza Kanjani i-Etidronate?

I-Etidronate isebenza ngokunciphisa amaseli abizwa ngokuthi ama-osteoclasts, anesibopho sokubhidliza izicubu zamathambo ezindala. Cabanga ngamathambo akho njengoba eziqhubeka zizilungisa, ngamaseli athile abhidliza ithambo elidala kanti amanye akha ithambo elisha.

Uma uthatha i-etidronate, inamathela emathanjeni akho futhi kwenza kube nzima ngamaseli okubhidliza ukuthi enze umsebenzi wawo. Lokhu kunika amaseli akho akha amathambo isikhathi esiningi sokudala izicubu zamathambo ezintsha, eziqinile.

Ngokuqondene nemithi yamathambo, i-etidronate ithathwa njengenketho enamandla aphakathi. Ayinamandla njengama-bisphosphonates amasha, kodwa isetshenziswe ngokuphepha iminyaka eminingi futhi isebenza kahle kubantu abaningi.

Kufanele Ngiyithathe Kanjani I-Etidronate?

Ukwenza i-etidronate ngendlela efanele kubalulekile ekusebenzeni nasekuphepheni. Kuzodingeka uyithathe esiswini esingenalutho, okungenani amahora angu-2 ngaphambi noma ngemuva kokudla noma yikuphi ukudla.

Nakhu okusebenza kahle kubantu abaningi lapho bethatha i-etidronate:

• Yithathe ekuseni ngovivi ngengilazi enkulu yamanzi acwebile
• Hlala uqonde (uhleli noma umi) okungenani imizuzu engama-30 ngemuva kokuyithatha
• Ungadli, ungaphuhi lutho ngaphandle kwamanzi, noma uthathe eminye imithi okungenani amahora angu-2
• Gwema ubisi, ikhofi, itiye, noma ijusi ngoba lokhu kungaphazamisa ukumuncwa

Lezi zinyathelo zisiza umzimba wakho ukuba umunce imithi ngendlela efanele futhi zinciphise ithuba lokucasuka kwesisu. Isikhathi singase sibonakale siqinile, kodwa senza umehluko wangempela ekusebenzeni kahle komuthi.

Kufanele Ngiyithathe Isikhathi Eside Kangakanani I-Etidronate?

Ubude bokwelashwa kwakho nge-etidronate buxhomeke esimweni sakho esithile nokuthi usabela kanjani emuthini. Ngesifo sikaPaget, abantu abaningi bayayithatha izinyanga eziyi-6 ngesikhathi, bese bephumula ukuze babone ukuthi amathambo abo enjani.

Udokotela wakho uzoqapha inqubekela phambili yakho ngokuhlolwa kwegazi okuvamile futhi mhlawumbe nokuskena kwamathambo. Abanye abantu badinga kuphela inkambo eyodwa yokwelashwa, kanti abanye bangase badinge izifundo eziphindaphindiwe eminyakeni eminingi.

Ukuvimbela i-osteoporosis, izikhathi zokwelashwa zingahluka kakhulu. Udokotela wakho uzocabangela izici ezinjengobudala bakho, ezinye izimo zempilo, nokuthi amathambo akho asabela kanjani ukuze anqume ubude obungcono kakhulu kuwe.

Yiziphi Imiphumela Eceleni Ye-Etidronate?

Abantu abaningi bayakwazi ukumelana ne-etidronate kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi abantu abaningi ababi nayo imiphumela emibi nhlobo.

Imiphumela emibi ejwayelekile ongase uyibone ihlanganisa:

• Ukucasuka kwesisu noma isicanucanu
• Ukuphuma kwendle noma izitulo ezixekile
• Ukunambitheka kwensimbi emlonyeni wakho
• Ukucindezeleka kwekhanda
• Ubuhlungu emathanjeni, emalungeni, noma emisipheni

Lezi zimpawu zivame ukuba mnene futhi zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Ukuthatha i-etidronate ngendlela eqondile kungasiza ekunciphiseni imiphumela emibi ehlobene nesisu.

Imiphumela emibi engathí sina ayivamile kodwa kubalulekile ukuyazi. Lokhu kungabandakanya ubuhlungu obukhulu besisu, ubunzima bokugwinya, noma ubuhlungu obusha emathanjeni obungapheli. Uma uhlangabezana nanoma yikuphi kwalokhu, xhumana nodokotela wakho ngokushesha.

Ngokuvamile, abanye abantu abathatha ama-bisphosphonates njenge-etidronate isikhathi eside bangase bathuthukise ukuqhekeka kwamathambo amathanga okungajwayelekile noma izinkinga zamathambo ohlakeni. Udokotela wakho uzokuqapha ngalezi zinkinga ezingavamile kakhulu ngesikhathi sokuhlolwa okuvamile.

Ubani Ongafanele Athathwe I-Etidronate?

I-Etidronate ayilungile kuwo wonke umuntu, futhi udokotela wakho uzocabangela izinto eziningana ngaphambi kokuyinika. Abantu abanezinkinga ezithile zezinso akufanele bathathe lo muthi ngoba imizimba yabo ayikwazi ukuwucubungula ngokuphepha.

Kufanele ugweme i-etidronate uma unenkinga yokugwinya noma izinkinga nge-esophagus yakho (ithubhu elixhuma umlomo wakho esiswini sakho). Umuthi ungacasula lezi zindawo uma unamathela.

Ezinye izimo lapho i-etidronate ingase ingafaneleki zihlanganisa:

• Isifo esibi sezinso
• Amazinga e-calcium aphansi kakhulu egazini lakho
• Ukungakwazi ukuhlala noma ukuma uqonde okungenani imizuzu engama-30
• Izilonda eziqhubekayo zesisu noma ukushisa kwenhliziyo okukhulu
• Ukukhulelwa noma ukuncelisa

Uma unezinye zalezi zimo, udokotela wakho angaxoxa ngezindlela zokwelapha ezingase zisebenze kangcono esimweni sakho.

Amagama Omkhiqizo we-Etidronate

I-Etidronate itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Didronel iyilena evame kakhulu ozoyibona. Amanye amagama omkhiqizo afaka i-Didrocal, ehlanganisa i-etidronate ne-calcium carbonate emjikelezweni wokwelapha olula.

Izinhlobo ze-generic ze-etidronate nazo ziyatholakala futhi zisebenza kahle njengezinhlobo ezinamagama omkhiqizo. Umkhemisi wakho angakusiza ukuthi uqonde ukuthi iyiphi inguqulo oyitholayo futhi aphendule noma yimiphi imibuzo mayelana nomuthi wakho othile.

Ezinye izindlela zokwelapha i-Etidronate

Uma i-etidronate ingasebenzi kahle kuwe noma ibangela imiphumela emibi, eminye imithi eqinisa amathambo iyatholakala. Ama-bisphosphonates amasha afana ne-alendronate (Fosamax) noma i-risedronate (Actonel) asebenza ngendlela efanayo kodwa angase athathwe kaningi.

Kubantu abangakwazi ukuthatha imithi yomlomo, izinketho ezinjenge-zoledronic acid (Reclast) zinikezwa kanye ngonyaka nge-IV. Abanye abantu bakhetha imithi efana ne-denosumab (Prolia), enikezwa njengesibhamu njalo ezinyangeni eziyisithu.

Udokotela wakho angase futhi acabangele ukwelashwa ngamahomoni, ama-selective estrogen receptor modulators, noma imithi emisha efana ne-teriparatide ezimweni ezithile. Ukukhetha okungcono kuncike esimweni sakho esithile, ezinye izinto zempilo, kanye nezintandokazi zomuntu siqu.

Ingabe i-Etidronate ingcono kune-Alendronate?

Kokubili i-etidronate ne-alendronate ziyimithi yamathambo esebenzayo, kodwa zinezinto ezibalulekile ezingafani. I-Alendronate ngokuvamile ithathwa njengeqinile futhi ithathwa kaningi, kuyilapho i-etidronate ivame ukusetshenziswa emijikelezweni enezikhawu phakathi kokwelashwa.

I-Alendronate ifundwe kabanzi ukuvimbela nokwelapha i-osteoporosis, ikakhulukazi kwabesifazane abase-postmenopausal. Ngokuvamile yiyona ekhethwa kuqala kubantu abaningi abane-osteoporosis ngenxa yalolu cwaningo oluqinile.

I-Etidronate ingase ithandwe ezimweni ezithile njengesifo sikaPaget noma uma othile edinga indlela enobumnene yokwelapha amathambo. Udokotela wakho uzocabangela isimo sakho esithile, okuhlanganisa umlando wakho wezokwelapha nokuthi uzithwala kanjani imithi, ukuze anqume ukuthi iyiphi inketho engcono kuwe.

Imibuzo Evame Ukubuzwa Nge-Etidronate

Ingabe i-Etidronate iphephile kubantu abanezifo zenhliziyo?

I-Etidronate ngokuvamile iphephile kubantu abanezifo zenhliziyo, njengoba ingayithinti ngokuqondile ukusebenza kwenhliziyo. Kodwa-ke, kufanele ngaso sonke isikhathi utshele udokotela wakho ngazo zonke izimo zakho zezokwelapha, okuhlanganisa nezinkinga zenhliziyo, ngaphambi kokuqala noma yimuphi umuthi omusha.

Abanye abantu abanezifo zenhliziyo bathatha imithi engase ihlangane ne-etidronate noma ithinte ukuthi iyasebenza kangakanani. Udokotela wakho angabuyekeza yonke imithi yakho ukuze aqiniseke ukuthi isebenza kahle ndawonye futhi alungise isikhathi uma kudingeka.

Ngingenzani uma ngiphuthelwa ukuthatha i-Etidronate eningi ngengozi?

Uma ngengozi uthatha i-etidronate eningi kunaleyo ebekiwe, ungapheli amandla, kodwa thatha isinyathelo ngokushesha. Phuza ingilazi yobisi egcwele noma thatha amaphilisi e-calcium uma unawo, njengoba i-calcium ingasiza ekunciphiseni imithi eyeqile.

Xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ikakhulukazi uma uthathe okuningi kakhulu kunomthamo wakho ovamile. Bangakunikeza iseluleko sokuthi yini okufanele uyibheke nokuthi ngabe udinga ukunakekelwa kwezokwelapha ngokushesha.

Izimpawu zokuthatha okuningi zingase zihlanganise isicanucanu esibi kakhulu, ukuhlanza, ubuhlungu besisu, noma amajaqamba emisipha. Ungazami ukuzenza uhlanze ngaphandle uma utshelwe ngokuqondile ukuthi wenze kanjalo nguchwepheshe wezokwelapha.

Ngingenzani uma ngiphuthelwa umthamo we-Etidronate?

Uma uphuthelwa umthamo we-etidronate, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma usengakwazi ukulandela imithetho efanele yesikhathi. Lokhu kusho ukuyithatha esiswini esingenalutho futhi ukwazi ukuhlala uqonde okungenani imizuzu engama-30 ngemva kwalokho.

Uma sekuseduze isikhathi somthamo wakho olandelayo, weqa umthamo owuphuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi.

Ukuphuthelwa umthamo ngezikhathi ezithile ngeke kulimaze ukwelashwa kwakho kakhulu, kodwa zama ukugcina ishejuli yakho ejwayelekile ngangokunokwenzeka ukuze uthole imiphumela engcono kakhulu.

Ngingayeka nini ukuthatha i-Etidronate?

Ungalokothi uyeke ukuthatha i-etidronate ngaphandle kokukhuluma nodokotela wakho kuqala, ngisho noma uzizwa ungcono. Izifo zamathambo zivame ukudinga ukuphathwa kwesikhathi eside, futhi ukuyeka imithi ngokushesha kungavumela isimo sakho ukuthi sibe sibi.

Udokotela wakho uzoqapha njalo intuthuko yakho ngezivivinyo zegazi futhi mhlawumbe nokuskena ukuminyana kwamathambo. Bazokwazisa uma kuphephile ukuyeka noma ukuphumula ekwelashweni ngokusekelwe ekutheni amathambo akho asabela kahle kangakanani.

Abanye abantu bangayeka ngemva kokuqeda inkambo ethile yokwelashwa, kanti abanye bangase badinge ukwelashwa okuqhubekayo ngamaphumulo phakathi. Isimo sakho ngasinye sizonquma indlela engcono kakhulu kuwe.

Ngingathatha yini izithasiselo ze-calcium ngenkathi ngise-Etidronate?

Yebo, izithasiselo ze-calcium zivame ukunconywa ngenkathi kuthathwa i-etidronate, kodwa isikhathi sibalulekile. Kufanele uhlukanise umthamo wakho we-etidronate ezithasiselweni ze-calcium okungenani ngamahora angu-2 ukuze ugweme ukuphazamisa ukumuncwa.

Odokotela abaningi batusa ukuthatha izithasiselo ze-calcium kusihlwa uma uthatha i-etidronate ekuseni. Lokhu kuqinisekisa ukuthi imithi yomibili isebenza ngempumelelo ngaphandle kokuphazamisana.

Udokotela wakho angase futhi ancome izithasiselo zikavithamini D ukusiza umzimba wakho ukuthi usebenzise i-calcium ngempumelelo. Njalo landela izincomo zabo ezithile mayelana nokuthi yiziphi izithasiselo okufanele uzithathe nokuthi uzithathe nini.