Fedratinib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Inrebic
Mayelana naleli khambi
IFedratinib isetshenziswa ekwelapheni i-myelofibrosis ephakathi-2 noma engozi enkulu, kufaka phakathi i-myelofibrosis eyiyona yokuqala noma yesibili (emva kwe-polycythemia vera ne-essential thrombocythemia). I-Myelofibrosis yinkinga yomgogodla wamathambo eyingozi ebomini ebonakala ngezimpawu ezilandelayo: ispleen enkulu (splenomegaly), ukukhahlela okukhulu, ukuvuvukala, ukubila ebusuku, ukulahlekelwa isisindo, ubuhlungu lwamathambo, noma ukukhathala okungavamile noma ubuthakathaka. Lolukhuni lutholakala kuphela ngomyalelo wochwepheshe wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucineni kokusebenzisa imithi, okuyingozi kokuthatha imithi kumele kuqhathaniswe nezinzuzo ezizokwenzeka. Lo ngumqulu ozothatha wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nokuthile okungavamile noma ukutholakala kwale mithi noma eminye imithi. Tshela odokotela wakho uma unezinye izinhlobo zokutholakala, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenamithi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-fedratinib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalimi ukusetshenziswa kwe-fedratinib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubaluleke kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma yimiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ayinconywa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ngokuvamile akunconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nanoma yimiphi imithi kungabangela ukuhlangana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza kuphela njengoba kunqunyiwe udokotela wakho. Umthamo wakho uyahlukahluka kuye ezivivinyweni zegazi futhi kudingeka ushintshwe izikhathi eziningi ukuze uthole ukuthi yini elisebenza kangcono kuwe. Ungasebenzisi leyeza eliningi, ungalisebenzisi kaningi, futhi ungalisebenzisi isikhathi eside kunalokho udokotela wakho akuqondisa. Leli leyeza liza ne-Medication Guide. Funda futhi ulandele imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Ungathatha leli leyeza ngokudla noma ngaphandle kokudla. Noma kunjalo, ukuthatha leli leyeza ngokudla okunemafutha amaningi kungavimbela isicanucanu nokugabha. Qhubeka usebenzisa leli leyeza isikhathi eside njengoba udokotela wakho ekutshelile. Ungashintshi umthamo wakho noma uyeke ukuthatha leli leyeza ngaphandle kokukhuluma nodokotela wakho kuqala. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa leli leyeza. I-grapefruit nejusi le-grapefruit zingashintsha inani leli leyeza elithathelwa emzimbeni. Umthamo waleli leyeza uzobahlukile kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela imithamo yaleli leyeza. Uma umthamo wakho uhlukile, ungawushintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani leyeza olithathayo liyahlukahluka kuye emandleni eleyeza. Futhi, inani lemithamo oyithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwemithamo, nobude besikhathi othatha leli leyeza kuyahlukahluka kuye esikhathini sokuphathwa kwempilo olisebenzisela lona. Uma uphuthelwa umthamo waleli leyeza, susa lowo mthamo ophuthelwe bese ubuyela esikhathini sakho sokuthatha imithi. Ungawandisi imithamo. Gcina leli leyeza esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungawumisisi. Gcina ungafinyeleleki kubantwana. Ungagcini leyeza eliphelile noma leyeza elingasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle njani noma yiliphi leyeza olungalisebenzisi.