Fenfluramine (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Mayelana naleli khambi
IFenfluramine isetshenziswa yodwa noma ngemithi eminye (isib. stiripentol, clobazam) ukwelapha ukubamba kwemisipha kubantu abane-Dravet syndrome (DS) ne-Lennox-Gastaut syndrome (LGS). Lolu dokotela lutholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi Fintepla® REMS (Uhlelo Lokuhlola Ubungozi Nokunciphisa Ubungozi.
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engavamile noma ebangelwa uketshezi kule mithi noma kunoma iyiphi eminye imithi. Tshela futhi ochwepheshe bezempilo uma unezinye izinhlobo zoketshezi, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-fenfluramine kubantwana abaneminyaka engaphansi kweminyaka emi-2. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingakhawulela ukusetshenziswa kwe-fenfluramine kubantu abadala. Noma kunjalo, abantu abadala banesikhathi esiningi sokuhlupheka ngezinkinga ze-liver, ikidney, noma inhliziyo ezihlobene nobudala, okuyingozi futhi kudinga ukulungiswa komthamo kwabaguli abamukela le mithi. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile ukuthi ochwepheshe bezempilo bakwazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akunconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili izidakamizwa. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukuhlangana. Xoxa nochwepheshe bezempilo bakho ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza kuphela njengoba kunqunyiwe udokotela wakho. Ungalithathi ngaphezulu, ungalithathi kaningi, futhi ungalithathi isikhathi eside kunalokho udokotela wakho akuqondile. Kubaluleke kakhulu ukuthi uqonde izidingo zeFintepla® REMS program, futhi uqonde incwajana yemithi yeFintepla®. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho uma unemibuzo. Buza umakhemikhali wakho ngencwajana yemithi uma ungenayo. Ungalithatha leli leyeza ngokudla noma ngaphandle kokudla. Linganisa leli leyeza ngesipuni somlomo esiphawuliwe. Isipuni noma ispoon esivamile sasekhaya singase singabi nesilinganiso esifanele sokuthola inani elifanele le-liquid. Inani leli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esembile. Ulwazi olulandelayo luhlanganisa kuphela amanani ajwayelekile aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondile ukwenza njalo. Inani leyeza olithathayo lixhomeke emandleni eleyeza. Futhi, inani lemithi olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwemithi, nobude besikhathi olithatha leli leyeza kuya ngenkinga yezokwelapha oyisebenzisayo. Uma uphuthelwa yidosi yaleli leyeza, yithathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sedosi yakho elandelayo, suka ngedosi ophuthelwe yona bese ubuyela esimweni sakho sokuthatha imithi. Ungawandisi ama-doses. Gcina leli leyeza esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungawumisisi. Gcina kubantwana. Ungagcini imithi eliphelile noma imithi engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle imithi oyisebenzisayo kanjani. Lahla noma iyiphi imithi engasetshenzisiwe ezinyangeni ezi-3 ngemuva kokuvula ibhodlela okokuqala.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.