Yini i-Fenoldopam: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Fenoldopam iyisidakamizwa esinamandla sokwehlisa umfutho wegazi esinikezwa nge-IV ezindaweni zase-hospital lapho umfutho wakho wegazi udinga ukwehla ngokushesha nangokuphepha. Yenzelwe ngqo izimo eziphuthumayo ze-hypertensive - lezo zimo ezingathi sína lapho umfutho wegazi ophezulu ngokuyingozi usongela izitho zakho futhi zidinga ukunakekelwa kwezokwelapha ngokushesha.

Cabanga nge-fenoldopam njengebhethri eliphuthumayo lesistimu yakho yenhliziyo nemithambo yegazi. Lapho umfutho wakho wegazi ukhuphukela emazingeni ayingozi, lo muthi usebenza ngokushesha ukuwubuyisela ebangeni eliphephile ngenkathi uvikela izinso zakho nezinye izitho ezibalulekile ngaleyo nqubo.

Yini i-Fenoldopam?

I-Fenoldopam iyisidakamizwa esenziwe ngendlela yokufakelwa esilingisa i-dopamine, ikhemikhali yemvelo emzimbeni wakho esiza ukulawula umfutho wegazi. Ingaphansi kohlu lwemithi ebizwa ngokuthi ama-dopamine receptor agonists, okusho ukuthi isebenzisa ama-receptors athile emithanjeni yakho yegazi nezinso.

Lo muthi utholakala kuphela njenge-intravenous infusion, okusho ukuthi unikezwa ngqo emgudwini wakho wegazi ngomugqa we-IV. Uzothola i-fenoldopam kuphela esibhedlela noma endaweni yezokwelapha lapho abahlinzeki bezempilo bengakuqapha ngokucophelela ngaso sonke isikhathi sokwelashwa.

Isetshenziselwani i-Fenoldopam?

I-Fenoldopam isetshenziselwa ikakhulukazi ukwelapha izimo eziphuthumayo ze-hypertensive - izimo ezisongela impilo lapho umfutho wakho wegazi ukhuphuka kakhulu kangangokuthi ungalimaza ubuchopho bakho, inhliziyo, izinso, noma ezinye izitho. Lezi zimo eziphuthumayo zidinga ukungenelela kwezokwelapha ngokushesha ukuvimbela ukulimala unomphela noma ukufa.

Abahlinzeki bezempilo bavame ukusebenzisa i-fenoldopam lapho umfutho wakho wegazi we-systolic (inombolo ephezulu) ifinyelela ku-180 mmHg noma ngaphezulu, noma umfutho wakho we-diastolic (inombolo engezansi) weqa i-120 mmHg, ikakhulukazi uma ehambisana nezimpawu ezinjengezinhlungu zekhanda ezinzima, ubuhlungu besifuba, noma ubunzima bokuphefumula.

Umuthi usetshenziswa futhi ezinqubweni ezithile zokuhlinzwa lapho ukulawulwa okunembile komfutho wegazi kubalulekile. Odokotela abathile bangase bawusebenzise ukuvikela ukusebenza kwezinso ezigulini eziyingozi yokulimala kwezinso ngesikhathi noma ngemva kokuhlinzwa.

Isebenza Kanjani I-Fenoldopam?

I-Fenoldopam isebenza ngokuvula izamukeli ze-dopamine emithanjeni yakho yegazi, okubangela ukuthi ziphumule futhi zikhule. Le nqubo, ebizwa ngokuthi i-vasodilation, inciphisa ukumelana inhliziyo yakho ebhekana nakho lapho ipompa igazi, okunciphisa ngokwemvelo umfutho wakho wegazi.

Okukwenza ukuthi i-fenoldopam ibe yinto ekhethekile yikhono layo lokuvikela izinso zakho ngenkathi yehlisa umfutho wegazi. Yandisa ukugeleza kwegazi ezinso zakho futhi izisiza ukuthi ziqede i-sodium namanzi amaningi, okusekela ngokuqhubekayo amazinga omfutho wegazi anempilo.

Umuthi uthathwa njengomuthi onamandla ngokulinganisela futhi usebenza ngokushesha - ngokuvamile uzobona izinguquko zomfutho wegazi kungakapheli imizuzu engu-15 ngemva kokuqala ukufakwa. Nokho, yakhelwe ukwehlisa umfutho wegazi kancane kancane kunokubangela ukwehla okungalindelekile okuyingozi.

Kufanele Ngiyithathe Kanjani I-Fenoldopam?

Awuzithatheli wena i-fenoldopam - inikezwa kuphela ochwepheshe bezempilo endaweni yasesibhedlela. Umuthi uza njengesixazululo esigxilile esincishisiwe futhi sinikezwe ngepompo yokufaka i-IV ukuze kulinganiswe kahle.

Ithimba lakho lezempilo lizoqala ngomthamo ophansi futhi liwukhulise kancane kancane ngokusekelwe endleleni umfutho wakho wegazi osabela ngayo. Bazokuqapha ngokuqhubekayo, behlola umfutho wakho wegazi njalo ngemizuzu embalwa ekuqaleni, bese-ke kaningi njengoba isimo sakho sizinzile.

Njengoba i-fenoldopam inikezwa ngomthambo, akukho imikhawulo yokudla noma izidingo ezikhethekile zokudla. Nokho, ithimba lakho lezokwelapha lingase likhawulele ukuthatha kwakho uketshezi noma lincomise ukuma okuthile ukuze kuthuthukiswe ukusebenza komuthi.

Kufanele Ngiyithathe Isikhathi Eside Kangakanani I-Fenoldopam?

Ukwelashwa nge-Fenoldopam kuvame ukuthatha amahora ambalwa kuya ezinsukwini eziningana, kuye ngokuthi umfutho wegazi lakho usabela kanjani kanye nesimo sakho esiphelele. Iningi leziguli lithola umuthi amahora angu-24 kuya kwangu-48 ngesikhathi esiphuthumayo somfutho wegazi ophezulu.

Iqembu lakho lezempilo lizokwehlisa kancane kancane umthamo kunokuthi liwuyeke kungazelelwe. Le nqubo yokunciphisa umthamo isiza ekuvikeleni umfutho wegazi lakho ukuthi ungabuyeli emazingeni ayingozi uma umuthi usuyekiwe.

Umgomo uwukukuguqula ukuthi uthathe imithi yomfutho wegazi ngomlomo ongayithatha ekhaya uma isimo sakho sesizinzile. Odokotela bakho bazosebenza nawe ukusungula uhlelo lokuphatha umfutho wegazi wesikhathi eside ngaphambi kokuthi uphume esibhedlela.

Yiziphi Imiphumela Eceleni ye-Fenoldopam?

Njengayo yonke imithi, i-fenoldopam ingabangela imiphumela emibi, nakuba eminingi iphathwa futhi iqashwe eduze yithimba lakho lezempilo. Ukuqonda le miphumela engaba khona kungakusiza ukuthi uxhumane kangcono nabahlinzeki bakho bezokwelapha mayelana nendlela ozizwa ngayo.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa ikhanda, ukubomvu noma ukufudumala ebusweni nasentanyeni yakho, kanye nesicanucanu. Le miphumela ivame ukwenzeka ngoba imithambo yakho yegazi iyanda, okuyindlela umuthi osebenza ngayo ukwehlisa umfutho wegazi lakho.

Ungase futhi uqaphele ukuthi inhliziyo yakho ishaya ngokushesha kunokujwayelekile. Lokhu kwenzeka ngoba umzimba wakho ekuqaleni uzama ukulinganisa umfutho wegazi ophansi ngokwandisa izinga lokushaya kwenhliziyo yakho. Ithimba lakho lezempilo liqapha lokhu eduze futhi lingashintsha umthamo wakho uma kudingeka.

Ezinye iziguli ziba nesiyezi noma ukukhathala, ikakhulukazi lapho zishintsha izikhundla. Yingakho cishe uzodinga ukuhlala embhedeni noma uhambe kancane ngosizo ngenkathi uthola i-fenoldopam.

Imiphumela emibi engathi sína kodwa engavamile ingabandakanya ukwehla okukhulu kwengcindezi yegazi, ukushaya kwenhliziyo okungajwayelekile, noma izinguquko ekusebenzeni kwezinso. Kodwa-ke, ngenxa yokuthi usesimweni esiqashwe, ithimba lakho lokunakekelwa kwezempilo lingakwazi ukubhekana ngokushesha nanoma yiziphi izimpawu ezikhathazayo.

Imiphumela emibi engavamile kodwa engathi sína ihlanganisa ukusabela komzimba ngaphandle, ukuphazamiseka okukhulu kwesigqi senhliziyo, noma ukungalingani okukhulu kwama-electrolyte. Ithimba lakho lezokwelapha liqapha ngokuqhubekayo lezi zinto ezingenzeka futhi linemithetho eqokiwe yokuziphatha ngokushesha uma zenzeka.

Ubani Ongafanele Athole I-Fenoldopam?

I-Fenoldopam ayifanele wonke umuntu, futhi ithimba lakho lokunakekelwa kwezempilo lizohlola ngokucophelela ukuthi iyona yini ekufanele isimo sakho esithile. Izimo ezithile zezokwelapha noma izimo zingenza lo muthi ungafaneleki noma uyingozi kuwe.

Akufanele uthole i-fenoldopam uma unokungezwani nayo noma nganoma iyiphi ingxenye yayo. Abantu abanezimo ezithile zenhliziyo, njengokuhluleka kwenhliziyo okukhulu noma izinhlobo ezithile zokushaya kwenhliziyo okungajwayelekile, kungenzeka bangabi ngabantu abafanelekayo kulo muthi.

Iziguli ezinokugula okukhulu kwezinso noma labo abasebenzisa i-dialysis badinga ukucatshangelwa okukhethekile, njengoba i-fenoldopam ithinta ukusebenza kwezinso. Odokotela bakho bazohlola izinzuzo ngokumelene nezingozi ezingaba khona ngokusekelwe empilweni yakho yezinso.

Abesifazane abakhulelwe ngokuvamile bagwema i-fenoldopam ngaphandle kokuthi izinzuzo zicace ngokusobala ukwedlula izingozi. Umuthi ungangena esithweni somzimba, futhi imiphumela yawo ezinganeni ezisakhula ayiqondakali ngokugcwele.

Abantu abathatha imithi ethile, ikakhulukazi leyo ethinta ingcindezi yegazi noma isigqi senhliziyo, bangase badinge ukulungiswa komthamo noma ukwelashwa okuhlukile. Ithimba lakho lokunakekelwa kwezempilo lizobuyekeza yonke imithi yakho yamanje ngaphambi kokuqala i-fenoldopam.

Amagama Omkhiqizo we-Fenoldopam

I-Fenoldopam itholakala ngaphansi kwegama lomkhiqizo elithi Corlopam e-United States. Leli yigama lomkhiqizo elisetshenziswa kakhulu ozohlangana nalo ezindaweni zasemtholampilo.

Izinhlobo ezivamile ze-fenoldopam zingase zitholakale, kuye ngokuthi i-formulary yesibhedlela sakho. Noma ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile, umuthi usebenza ngendlela efanayo futhi unikeza izinzuzo zokwelapha ezilinganayo.

Ezinye izindlela ze-Fenoldopam

Eminye imithi eminingi ingelapha izimo eziphuthumayo ze-hypertensive, yize ngayinye inezindlela zokusebenza ezihlukene kanye nezinzuzo ezithile. Ithimba lakho lokunakekelwa kwezempilo lizokhetha inketho engcono kakhulu ngokususelwa ezimweni zakho kanye nomlando wakho wezokwelapha.

I-Nicardipine ngomunye umuthi we-IV ovame ukusetshenziswa ezimweni eziphuthumayo ze-hypertensive. Ingaphansi ekilasini elihlukile lemithi elibizwa ngokuthi ama-calcium channel blockers futhi lingase lithandwe ezimweni ezithile, njengalapho unezimo ezithile zenhliziyo.

I-Esmolol, i-beta-blocker esebenza ngokushesha, inikeza enye indlela, ewusizo ikakhulukazi lapho ukulawulwa kwengcindezi yegazi okusheshayo kudingeka futhi imiphumela yomuthi idinga ukuguqulwa kalula.

I-Clevidipine imelela inketho entsha enikeza ukulawulwa okunembile kakhulu kwengcindezi yegazi futhi ingavalwa ngokushesha uma kudingeka. Ezinye izibhedlela zikhetha lo muthi ngezindlela ezithile zokuhlinzwa.

Ezinye izindlela ezingasetshenziswa kancane zihlanganisa i-hydralazine, i-labetalol, noma i-nitroglycerin engaphansi kolimi, yize lezi zingase zibe nemiphumela engabikezelwa kakhulu noma izikhathi ezide zokusebenza.

Ingabe i-Fenoldopam ingcono kune-Nicardipine?

Akukho kokubili i-fenoldopam noma i-nicardipine okuyinto

I-Nicardipine ingase ikhethwe uma unezimo ezithile zenhliziyo noma uma kudingeka impendulo yomfutho wegazi ongabikezeleka kakhulu. Inohlu oluhlukile lwemiphumela emibi futhi ingase ithandwe kangcono ezigulini ezithile.

Zombili lezi zithako zisebenza ngokushesha futhi zingalawulwa ngokuqondile ngokufakwa kwe-IV. Ukukhetha kuvame ukuncika kulwazi lukadokotela wakho ngemithi ngayinye kanye nezimo zakho zezokwelapha ezithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Fenoldopam

Q1. Ingabe i-Fenoldopam iphephile kubantu abanezifo zenhliziyo?

I-Fenoldopam ingasetshenziswa ngokuphepha kubantu abaningi abanezifo zenhliziyo, kodwa idinga ukuqapha okucophelelayo nokulungiswa komthamo. Ithimba lakho lezempilo lizohlola isimo sakho senhliziyo esithile ukuze linqume ukuthi i-fenoldopam ilungele yini wena.

Abantu abanezinhlobo ezithile zokuhluleka kwenhliziyo noma ukushaya kwenhliziyo okungajwayelekile bangase badinge izinyathelo zokuphepha ezikhethekile noma imithi ehlukile. Umuthi ungakhuphula izinga lokushaya kwenhliziyo, okungase kungabi kuhle kuwo wonke umuntu onezifo zenhliziyo.

Q2. Kufanele ngenzeni uma ngithola imiphumela emibi evela ku-Fenoldopam?

Njengoba i-fenoldopam inikezwa endaweni yasesibhedlela, kufanele wazise ngokushesha umhlengikazi wakho noma ithimba lezempilo mayelana nanoma yimiphi imiphumela emibi oyitholayo. Baqeqeshwe ukubona nokuphatha le miphumela ngokushesha.

Ungazami ukuphatha imiphumela emibi uwedwa noma ulinde ukubona ukuthi iyathuthuka yini. Ngisho nezimpawu ezithambile njengokugajuka noma isicanucanu kufanele zibikwe, njengoba zingase zibonise isidingo sokulungiswa komthamo.

Q3. Ingabe i-Fenoldopam ingabangela izinkinga zezinso?

I-Fenoldopam empeleni yakhelwe ukuvikela izinso zakho kunokuzilimaza. Yandisa ukugeleza kwegazi ezinso futhi ingasiza ukulondoloza ukusebenza kwezinso ngesikhathi sezimo eziphuthumayo ze-hypertensive.

Nokho, njenganoma yimuphi umuthi othinta umfutho wegazi, i-fenoldopam kufanele isetshenziswe ngokucophelela kubantu abanezifo zezinso ezikhona. Ithimba lakho lezempilo lizogada ukusebenza kwezinso zakho ngokucophelela ngaso sonke isikhathi sokwelashwa.

Umbuzo 4. Ngokushesha kangakanani i-Fenoldopam iqala ukusebenza?

I-Fenoldopam ngokuvamile iqala ukwehlisa umfutho wegazi kungakapheli imizuzu engu-15 ngemuva kokuqala ukufakwa. Uzobona umphumela omkhulu kungakapheli imizuzu engama-30 kuya kwengama-60, kuye ngomthamo wakho nokuphendula komuntu ngamunye.

Ithimba lakho lezempilo lizogada umfutho wakho wegazi ngokuqhubekayo ngalesi sikhathi, lenze izinguquko zomthamo njengoba kudingeka ukuze kuzuzwe umfutho wegazi oqondiwe ngokuphepha nangokuhamba kancane.

Umbuzo 5. Ngizodinga yini ukuthatha imithi yomfutho wegazi ngemuva kwe-Fenoldopam?

Abantu abaningi abathola i-fenoldopam bazodinga imithi yomfutho wegazi yesikhathi eside ukuvimbela izimo eziphuthumayo ze-hypertensive esikhathini esizayo. Ithimba lakho lezempilo lizosebenza nawe ukusungula uhlelo olufanele lwemithi yomlomo ngaphambi kokuthi uphume esibhedlela.

Ushintsho olusuka ku-fenoldopam luye emithini yomlomo luhlelwe ngokucophelela ukuqinisekisa ukuthi umfutho wakho wegazi uhlala uzinzile. Odokotela bakho bazokusiza futhi uqonde izinguquko zendlela yokuphila ezingasekela ukulawulwa komfutho wegazi wesikhathi eside.