Fentanyl (indlela yomlomo, indlela yomlomo, indlela yolwemi)
Imikhiqizo etholakalayo
Abstral, Actiq, Fentora, Onsolis, Subsys
Mayelana naleli khambi
IFentanyl isetshenziswa ekwelapheni ubuhlungu obukhulu kubantu abane-kansa. Isetshenziswa ekwelapheni ubuhlungu bekansa obukhulu, okuyizikhathi zokwanda kobhlungu “okuqhekeka” ngemuva kokusetshenziswa kwemithi yobhlungu ejwayelekile. IFentanyl iyingxenye yeqembu lemithi ebizwa ngokuthi yi-opioid analgesics.Isetshenziswa kuphela kulabo abasebenzisa i-opioid analgesics kakade. IFentanyl isebenza ohlelweni oluphakathi lolwemi (CNS) ukuze iphephe ubuhlungu. Ezinye zeziphumo zayo ezibuhlungu nazo zibangelwa imisebenzi e-CNS. Uma i-opioid isetshenziswa isikhathi eside, ingaba yinto yokujwayela noma ibangela ukuncika ngokwengqondo noma ngokomzimba. Noma kunjalo, ngaphansi kokunakekelwa okuqinile kwesiphepheli sezokunakekelwa kwezempilo, abantu abanobuhlungu obuqhubekayo akufanele bavumele ukwesaba ukuncika kubavimbe ekusebenziseni i-opioids ukuze baphephe ubuhlungu. Ukuncika ngokwengqondo (ukuzithanda) kuncane kakhulu uma i-opioids isetshenziswa ngenhloso. Ukuncika ngokomzimba kungabangela izimpawu zokuhoxa uma ukwelashwa kuphelile ngokuzumayo. Izimpawu zokuhoxa zivame ukuvimbeka ngokunciphisa kancane umthamo isikhathi esithile ngaphambi kokuba umuthi uphele ngokuphelele. Xoxa nodokotela wakho ngezinzuzo zale mithi nokuthi ungazivimbela kanjani izimpawu zokuhoxa. Lolu lwemi lutholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi TIRF (Transmucosal Immediate Release Fentanyl) REMS (Risk Evaluation and Mitigation Strategy) program. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahlweni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumgwebo wena nodokotela wakho ozowenza. Ngale mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluhlukile noma ukusabela okungokwe-alergi kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokungezwani, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-fentanyl kubantwana abaneminyaka engaphansi kwengu-18 ubudala nge-Abstral®, i-Fentora®, i-Onsolis®, kanye ne-Subsys®amagama, nakubantwana abaneminyaka engaphansi kwengu-16 ubudala nge-Actiq®brand. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube yimanje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-fentanyl kubantu abadala. Noma kunjalo, iziguli ezikhulile zingaba nokuzwela okukhulu kwimiphumela ye-opioid analgesics kunabantu abadala abasebancane futhi kungenzeka kakhulu ukuthi babe nezinkinga ze-lung noma zezinso ezihlobene nobudala, okungase kudinge ukunakekelwa nokulungiswa komthamo kwabaguli abamukela i-fentanyl ukuze kugwenywe imiphumela emibi enzima. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba imithi ethile ingafanele isetshenziswe ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingase isetshenziswe ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingase zidingeke. Uma uthatha le mithi, kubaluleke kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye zezinto ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Imithi ethile akufanele isetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba ngemithi ethile kungase futhi kubangele ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungakugwenyeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungase kuchaphazele ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Sebenzisa le mishanguzo kuphela njengoba kunqunyiwe udokotela wakho. Ungayisebenzisi ngokweqile, ungayisebenzisi kaningi, futhi ungayisebenzisi isikhathi eside kunalokho udokotela wakho akuqondile. Kubalulekile kakhulu ukuthi uqonde imithetho yohlelo lwe-TIRF REMS ukuvimbela ukulutha, ukusebenzisa kabi, nokusebenzisa kabi i-oxycodone. Lona umuthi kufanele ubuye ube ne-Medication Guide. Funda futhi ulandele lezi zinkomba ngokucophelela. Funda futhi njalo lapho ugcwalisa iresiphi yakho uma kungenzeka kukhona ulwazi olusha. Buza udokotela wakho uma unemibuzo. Sebenzisa kuphela uhlobo lolu mishanguzo udokotela wakho alubhalile. Amabhizinisi ahlukene angase angasebenzi ngendlela efanayo. Gcina umuthi ephaketheni lokuqala le-blister. Vula iphakheji ngaphambi kokusebenzisa. Amathebulethi e-Abstral®: Ama-lozenges e-Actiq®: Amathebulethi e-buccal e-Fentora®: Ifilimu ye-buccal ye-Onsolis®: Isikhuni se-Subsys® sublingual: Inani lolu mishanguzo lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo elebhelini. Ulwazi olulandelayo luhlanganisa kuphela amanani ajwayelekile alo muthi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondile ukwenza njalo. Inani lomuthi owuthatha lixhomeke emandleni omthombo. Futhi, inani lezinani ozithatha nsuku zonke, isikhathi esivunyelwe phakathi kwezinani, nobude besikhathi othatha umuthi kuya ngenkinga yezokwelapha oyisebenzisela umuthi. Gcina umuthi esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungawagqabi. Gcina ungafinyeleleki kubantwana. Ungagcini imishanguzo eliphelile noma imishanguzo engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle kanjani noma yimiphi imishanguzo ongayisebenzisi. Amathebulethi e-Abstral®: Uma unemibuzo mayelana nendlela engcono kakhulu yokulahla amathebulethi ongayisebenzisi, buza u-pharmacist wakho noma shayela u-1-888-227-8725. Ama-lozenges e-Actiq®: Uma unemibuzo mayelana nendlela engcono kakhulu yokulahla ama-lozenges ongayisebenzisi, buza u-pharmacist wakho noma shayela u-1-800-896-5855. Amathebulethi e-Fentora®: Uma unemibuzo mayelana nendlela engcono kakhulu yokulahla amathebulethi ongayisebenzisi, buza u-pharmacist wakho noma shayela u-1-800-896-5855. Ifilimu ye-Onsolis®: Uma unemibuzo mayelana nendlela engcono kakhulu yokulahla amafilimu ongayisebenzisi, buza u-pharmacist wakho noma shayela u-1-800-526-3840. Isikhuni se-Subsys®: Beka iyunithi yokusabalalisa esetshenzisiwe esikhwameni sokulahla. Valela isikhwama sokulahla bese usiphosa esitsheni samasibi esingafinyeleleki kubantwana. Ngayo yonke iyunithi yokusabalalisa engavulwanga, sebenzisa ibhodlela lokulahla ukuze ukhulule ulwelo kuyo yonke iyunithi. Beka ibhodlela lokulahla esikhwameni bese ulivala. Phonsa isikhwama esitsheni samasibi esingafinyeleleki kubantwana. Uma unemibuzo, shayela u-1-877-978-2797.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.