Yini i-Fentanyl (Buccal, Oromucosal, Sublingual): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Fentanyl elethwa ngezicubu zomlomo wakho iyimithi enamandla ebekelwe abantu abaphila nobuhlungu obukhulu, obuqhubekayo. Lolu hlobo lwe-fentanyl lusebenza ngokuncibilika ngasehlathini lakho, ngaphansi kolimi lwakho, noma ngasemathunjini akho, okuvumela umuthi ukuthi ungene ngokushesha emsingeni wakho wegazi ngezicubu ezibucayi emlonyeni wakho.

Lezi zinhlobo ezikhethekile ze-fentanyl zigcinelwe iziguli ezivele zithatha imithi ye-opioid ebusuku nemini futhi zidinga ukukhululeka kobuhlungu okwengeziwe ngezikhathi zokugqashuka okungazelelwe. Udokotela wakho uzokunika lo muthi kuphela uma ezinye izindlela zokwelapha ubuhlungu zingazange zinikeze ukukhululeka okwanele esimweni sakho esithile.

Yini i-Fentanyl (Buccal, Oromucosal, Sublingual)?

I-Fentanyl elawulwa ngezicubu zomlomo iyimithi ebuhlungu ye-opioid esebenza ngokushesha eza ngezinhlobo eziningana ezenzelwe ukuncibilika emlonyeni wakho. Ngokungafani namaphilisi ogwinyayo, le mithi isebenza ngokumuncwa ngokuqondile ngezicubu ezithambile zomlomo wakho, okuhlanganisa izihlathi zakho, amathambo, nendawo engaphansi kolimi lwakho.

Lo muthi unamandla kakhulu kunezinye izidambisi zokucasuka ongase uzijwayele. Eqinisweni, i-fentanyl cishe iphindwe ama-50 kuya kwangu-100 kunamandla kune-morphine, okusho ukuthi ngisho namanani amancane anganikeza ukukhululeka okukhulu kobuhlungu kulabo abakudingayo.

Izindlela ezihlukene zokuphatha zihlanganisa amaphilisi e-buccal ancibilika ngasehlathini lakho, amaphilisi e-sublingual aya ngaphansi kolimi lwakho, namafilimu omlomo noma ama-lozenges asebenza kuwo wonke umlomo wakho. Ifomu ngalinye lenzelwe ukuletha imithi ngokushesha uma uhlangabezana neziqephu zobuhlungu obuqhumayo.

Isetshenziselwani i-Fentanyl (Buccal, Oromucosal, Sublingual)?

Lo muthi unikezelwe ngokuqondile ukuphatha ubuhlungu bomdlavuza obuqhamukayo kubantu abadala asebevele bekhuthazelela ukwelashwa nge-opioid. Ubuhlungu obuqhamukayo bubhekisela ezigamekweni ezingazelelwe zobuhlungu obukhulu obenzeka ngisho noma uthatha imithi ejwayelekile yokudambisa ubuhlungu.

Udkt wakho angase akunikeze lo muthi uma unobuhlungu obuhlobene nomdlavuza obungalawulwa ngokwanele yindlela yakho yamanje yokuphatha ubuhlungu. Umuthi wenzelwe ukuhlinzeka ngokusheshisa ngesikhathi salezo zikhathi ezingalindelekile lapho ubuhlungu bakho bukhuphuka ngaphezu kwezinga lakho eliyisisekelo.

Kubalulekile ukuqonda ukuthi lo muthi awuhloselwe ubuhlungu obungajwayelekile, ukungakhululeki ngemva kokuhlinzwa, noma ubuhlungu obubangelwa ukulimala. Umphakathi wezokwelapha ugcina lezi zindlela ezinamandla kubantu abanezimo ezinzima, eziqhubekayo asebevele bebonise ukuthi bangawasebenzisa ngokuphepha imithi ye-opioid.

Isebenza Kanjani I-Fentanyl (Buccal, Oromucosal, Sublingual)?

Lo muthi usebenza ngokubopha kuma-receptors athile ebuchosheni bakho nasemgogodleni obizwa ngokuthi ama-opioid receptors. Lapho i-fentanyl inamathisela kula ma-receptors, ivimba izimpawu zobuhlungu ekuhambeni ngohlelo lwakho lwezinzwa ebuchosheni bakho, inikeze ukukhululeka okukhulu kobuhlungu.

Isizathu sokuthi lezi zinhlobo eziphethwe ngomlomo zisebenze ngokushesha kangako ukuthi umlomo wakho uqukethe imithambo eminingi yegazi eseduze nendawo. Lapho umuthi uncibilika emhlathini wakho, ngaphansi kolimi lwakho, noma emagunjini akho, ungena ngokushesha emgudwini wakho wegazi, ngokuvamile unikeza ukukhululeka kungakapheli imizuzu eyi-15 kuya kwengama-30.

Lokhu kuthathwa njengomuthi onamandla kakhulu emkhakheni wezokwelapha. Amandla asho ukuthi angaphatha ngempumelelo ubuhlungu obukhulu, kodwa futhi kudinga ukuqapha ngokucophelela nokulinganisa okunembile ukuze kuqinisekiswe ukuphepha kwakho nokulawulwa okuhle kobuhlungu.

Kufanele Ngiyithathe Kanjani I-Fentanyl (Buccal, Oromucosal, Sublingual)?

Indlela othatha ngayo lo muthi ixhomeke ohlotsheni oluthile udokotela wakho akubhalisele lona, kodwa zonke izinhlobo zidinga ukunakekelwa ngokucophelela ngendlela efanele. Umhlinzeki wakho wezempilo uzokunika imiyalelo enemininingwane eqondene nokwakheka okubhalwe ngudokotela wakho.

Kumaphilisi e-buccal, uzobeka iphilisi phakathi kwesihlathi sakho nezinsini, uvumele ukuthi incibilike ngokuphelele ngemizuzu engama-15 kuya kwengama-30. Gwema ukuhlafuna, ukuncela, noma ukugwinya iphilisi lonke, ngoba lokhu kungaba yingozi futhi ngeke kunikeze ukukhululeka kobuhlungu obuhloswe ngabo.

Uma usebenzisa amaphilisi e-sublingual, uwabeke ngaphansi kolimi lwakho bese uwavumela ukuthi ancibilike ngokwemvelo. Ungadli, ungaphuhi, noma ukhulume ngenkathi umuthi uncibilika, ngoba lokhu kungaphazamisa ukumuncwa okufanele.

Nawa amanye amathrekhi abalulekile asebenza kuzo zonke izinhlobo zalo muthi:

• Njalo sebenzisa izandla ezihlanzekile, ezomile lapho uphatha umuthi
• Ungadli noma uphuze lutho ngenkathi umuthi uncibilika
• Gwema ukubhema noma ukusebenzisa imikhiqizo kagwayi ngesikhathi sokuphatha
• Ungalokothi unqume, uphule, noma uhlafune noma yiluphi uhlobo lwalo muthi
• Sebenzisa ngqo umthamo obhalwe ngudokotela wakho

Umlomo wakho kufanele ube manzi kodwa ungabi manzi ngokweqile uma usebenzisa lo muthi. Uma umlomo wakho uzizwa womile kakhulu, thatha isiphuzo esincane samanzi ngaphambi kokubeka umuthi, kodwa ungaphuhi lutho uma usuqalile inqubo yokuncibilika.

Kufanele Ngithathe Isikhathi Esingakanani I-Fentanyl (Buccal, Oromucosal, Sublingual) ?

Ubude bokwelashwa ngalo muthi buxhomeke ngokuphelele esimweni sakho sezokwelapha kanye nendlela umzimba wakho osabela ngayo ekwelashweni. Udokotela wakho uzohlola njalo ukuthi usadinga yini leli zinga lokuphathwa kobuhlungu futhi alungise uhlelo lwakho lokwelashwa ngokufanele.

Abantu abaningi abanezinhlungu ezihlobene nomdlavuza bangase badinge lo muthi isikhathi eside, kanti abanye bangase bawusebenzise isikhathi esifushane kuye ngokuqhubeka kokwelashwa kwabo. Ithimba lakho labanakekeli bezempilo lizosebenza nawe ukuthola ubude bokwelashwa obufanele isimo sakho esithile.

Ungayeki ukuthatha lo muthi kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Ngenxa yokuthi i-fentanyl iyi-opioid enamandla, ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa ezingakhululeki, futhi udokotela wakho angase adinge ukunciphisa umthamo wakho kancane kancane ngokuhamba kwesikhathi ukuze aqinisekise ukunethezeka kwakho nokuphepha kwakho.

Yiziphi Imiphumela Eceleni ye-Fentanyl (Buccal, Oromucosal, Sublingual)?

Njengayo yonke imithi, i-fentanyl ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi okulindelekile kungakusiza ukuthi uzizwe ulungile futhi wazi ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isicanucanu, isiyezi, ukozela, nokuqunjelwa. Le miphumela ivame ukungabonakali njengoba umzimba wakho ujwayela umuthi, kodwa yazisa udokotela wakho uma iqhubeka noma iphazamisa imisebenzi yakho yansuku zonke.

Abanye abantu nabo bathola umlomo owomile, ikhanda, noma izinguquko ekudleni. Ungase uqaphele ukucasuka okuthile noma ubuhlungu emlonyeni wakho lapho umuthi uncibilika khona, okuvame ukuzixazulula ngokwako.

Imiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha ihlanganisa:

• Ukuphefumula kanzima kakhulu noma ukuphefumula kancane, okungajulile
• Ukozela okukhulu noma ubunzima bokuhlala uqaphele
• Ukudideka noma izinguquko ezingavamile esimweni sengqondo
• Isiyezi esikhulu noma ukuquleka
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile

Uma uthola noma yiziphi zalezi zimpawu ezingathi sína, funa ukunakekelwa kwezimo eziphuthumayo ngokushesha. Le miphumela ayivamile kodwa ingaba yingozi ekuphileni uma ingelashwa ngokushesha.

Ezinye izinto ezingavamile kodwa ezibalulekile ezingaba khona zihlanganisa izinguquko zemizwa, ubunzima bokulala, noma amaphupho angajwayelekile. Ukusabela komzimba wakho kulo muthi kungahluka, futhi ithimba lakho lezempilo lilapho ukukusiza ukuba ubhekane nanoma yiziphi izinkathazo ezingase zivele.

Ubani Ongafanele Athathe I-Fentanyl (Buccal, Oromucosal, Sublingual)?

Lo muthi awufanele wonke umuntu, futhi izimo ezithile zezokwelapha noma izimo zenza kungaphephile ukuwusebenzisa. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuchazela lo muthi.

Akufanele usebenzise lo muthi uma ungazange usebenzise imithi ye-opioid njalo okungenani isonto elilodwa. Umzimba wakho udinga ukujwayela ama-opioid ngaphambi kokuthi ukwazi ukusebenzisa le fomula enamandla ngokuphepha.

Abantu abanezinkinga ezithile zokuphefumula, okuhlanganisa isifuba esikhulu noma isifo sokuphefumula esingamahlalakhona (COPD), kungenzeka bangakwazi ukusebenzisa lo muthi ngokuphepha. Umuthi unganciphisa ukuphefumula kwakho, okungaba yingozi uma usuvele unezinkinga zokuphefumula.

Ezinye izimo ezingakuvimbela ukuthi usebenzise lo muthi zihlanganisa:

• Izinkinga ezinzima zesibindi noma izinso
• Ukulimala ekhanda noma izimo zobuchopho ezenyusa ingcindezi ekhakhazini lakho
• Ukuvaleka kwesisu noma amathumbu
• Umlando wokulutheka kwezidakamizwa noma utshwala (ngaphandle uma usohlelweni lokwelashwa oluqondisiwe)
• Ezinye izinkinga zesigqi senhliziyo

Ukukhulelwa nokuncelisa nazo zidinga ukucatshangelwa okukhethekile, njengoba lo muthi ungakuthinta wena nomntwana wakho. Udokotela wakho uzoxoxa ngezingozi nezinzuzo uma ukhulelwe noma uhlela ukukhulelwa.

Amagama Omkhiqizo we-Fentanyl

Lo muthi uyatholakala ngaphansi kwamagama amaningi omkhiqizo, ngalinye lenzelwe izindlela ezithile zokuphatha ngamathishu omlomo wakho. Amabhrendi avame ukuchazwa kakhulu ahlanganisa i-Actiq, eza njenge-lozenge endukwini, ne-Fentora, etholakala njengamaphilisi e-buccal.

Eminye izinhlobo zamagama ongahlangana nazo zihlanganisa i-Abstral yamaphilisi angaphansi kolimi, i-Onsolis yamafilimu e-buccal, ne-Subsys yesifutho esingaphansi kolimi. Uhlobo ngalunye lwenziwe ngqo ukuletha imithi ngezingxenye ezahlukene zomlomo wakho.

Udokotela wakho uzokhetha uhlobo oluthile kanye nokwakheka okuhambisana nezidingo zakho kanye nesimo sakho sezokwelapha. Ungashintshi phakathi kwezinhlobo ezahlukene noma ukwakheka ngaphandle kokubonisana nomhlinzeki wakho wezempilo, njengoba kungase kube namazinga ahlukene okumuncwa kanye nezidingo zokulinganisa.

Ezinye izindlela ze-Fentanyl

Uma lo muthi ungakulungele noma unganikezi ukukhululeka okwanele kobuhlungu, udokotela wakho unezinketho eziningi ezingezinye okufanele azicabangele. Eminye imithi ye-opioid esheshayo ihlanganisa i-morphine ekhishwe ngokushesha, i-oxycodone, noma i-hydromorphone, nakuba lezi zisebenza ngendlela ehlukile kunamafomu anikezwa ngomlomo.

Abanye abantu bayazuza ezindleleni ezahlukene zokulethwa komuthi ofanayo, njengama-fentanyl patches anikeza imithi eqhubekayo ngesikhumba sakho ezinsukwini ezimbalwa. Imithi yobuhlungu ejovwayo enikezwa abahlinzeki bezempilo imele enye indlela yokukhululeka kobuhlungu obukhulu.

Izindlela ezingezona ze-opioid nazo zingaba yingxenye yohlelo lwakho lokuphatha ubuhlungu, okuhlanganisa ama-nerve blocks, i-physical therapy ekhethekile, noma ukwelashwa okwengezelelwe njenge-acupuncture. Ithimba lakho lezempilo lizosebenza nawe ukuthola inhlanganisela yokwelashwa enikeza ukukhululeka okungcono kobuhlungu ngemiphumela emincane.

Ingabe i-Fentanyl (Buccal, Oromucosal, Sublingual) ingcono kune-Morphine ekhishwe ngokushesha?

Yomibili imithi iyasebenza ekuphatheni ubuhlungu obukhulu, kodwa isebenza ngendlela ehlukile futhi inezinzuzo ezihlukile kuye ngezidingo zakho ezithile. I-Fentanyl enikezwa ngezicubu zomlomo ngokuvamile isebenza ngokushesha kune-morphine ekhishwe ngokushesha, ngokuvamile inikeza ukukhululeka phakathi kwemizuzu eyi-15 kuya kwengama-30 uma kuqhathaniswa nemizuzu engama-30 kuya kwengama-60 ye-morphine yomlomo.

I-fentanyl ethulwa ngomlomo inamandla kakhulu kune-morphine, okusho ukuthi imithamo emincane inganikeza ukukhululeka kobuhlungu okufanayo. Lokhu kungaba usizo kubantu abanobunzima bokugwinya amaphilisi noma abadinga ukukhululeka okusheshayo ezikhathini zobuhlungu eziphuthumayo.

Nokho, i-morphine ekhishwa ngokushesha isetshenziswe ngokuphepha amashumi eminyaka futhi ingase ifaneleke kakhulu kubantu abaqala nje ukwelashwa nge-opioid. Udokotela wakho uzocabangela izinto ezifana nemithi yakho yamanje yokwelapha ubuhlungu, ubukhulu bobuhlungu bakho, kanye nekhono lakho lokusebenzisa imithi ngokuphepha lapho enquma ukuthi iyiphi inketho engcono kakhulu kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Fentanyl (Buccal, Oromucosal, Sublingual)

Ingabe i-Fentanyl (Buccal, Oromucosal, Sublingual) iphephile kubantu abanezifo zezinso?

Abantu abanezifo zezinso bangasebenzisa le mithi ngokuphepha, kodwa idinga ukuqashwa ngokucophelela yithimba lakho lezempilo. Izinso zakho zisiza ukucubungula nokukhipha imithi emzimbeni wakho, ngakho izinkinga zezinso zingathinta ukuthi imithi ihlala isikhathi esingakanani emzimbeni wakho.

Uma unezinkinga zezinso eziphakathi nendawo, udokotela wakho angase akunikeze le mithi ngokuhlolwa okuvame kakhulu ukuze aqinisekise ukuthi isebenza ngokuphepha. Kubantu abanezifo zezinso ezinzima, udokotela wakho angase akhethe omunye umuthi wokwelapha ubuhlungu noma alungise umthamo wakho ukuze avimbele imithi ukuthi ingaqongeleli emzimbeni wakho.

Kufanele ngenzeni uma ngisebenzisa i-Fentanyl eningi ngengozi?

Uma ngengozi usebenzisa okungaphezu komthamo wakho obekiwe, funa usizo lwezempilo oluphuthumayo ngokushesha ngokushayela u-911 noma ukuya egumbini eliphuthumayo eliseduze. Ukuthatha i-fentanyl eningi kungabangela izinkinga zokuphefumula ezisongela impilo, futhi ukwelashwa okusheshayo kwezokwelapha kubalulekile.

Izimpawu zokuthi kungenzeka ukuthi usebenzise kakhulu zihlanganisa ukozela okukhulu, ubunzima bokuphefumula, ukuphefumula kancane noma okungashoni, izindebe eziluhlaza noma izinzipho, noma ukulahlekelwa ukwazi. Ungalindi ukubona ukuthi izimpawu ziyathuthuka yini zodwa, ngoba lokhu kungaba isimo esiphuthumayo sezokwelapha esidinga ukwelashwa ngokushesha ochwepheshe.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Fentanyl?

Lo muthi uvame ukusetshenziswa kuphela uma uhlangabezana nobuhlungu obuqinile, ngakho ukuphuthelwa umthamo ngokuvamile akuyona into ekhathazayo ngomqondo ovamile. Kufanele usebenzise lo muthi kuphela uma empeleni uhlangabezana nobuhlungu obukhulu obenzelwe ukulapha.

Uma uthatha lo muthi ngeshejuli ejwayelekile njengoba kunqunywe udokotela wakho, thatha umthamo ophuthelwe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungaba yingozi.

Ngingayeka nini ukuthatha i-Fentanyl?

Kufanele uyeke kuphela ukuthatha lo muthi ngaphansi kokuqondisa komhlinzeki wakho wezempilo. Udokotela wakho uzokusiza ukuthi unqume ukuthi kufanelekile nini ukuyeka umuthi ngokuya ngamazinga akho obuhlungu, impilo yonke, kanye nokuqhubeka kokwelashwa.

Uma ubusetshenzisa lo muthi njalo, udokotela wakho cishe uzoncoma ukunciphisa kancane umthamo wakho ngokuhamba kwesikhathi kunokuyeka kungazelelwe. Le ndlela isiza ekuvikeleni izimpawu zokuhoxiswa futhi iqinisekisa ukuthi ubuhlungu bakho buqhubeka bulawulwa kahle ngesikhathi sokushintsha.

Ngingashayela ngesikhathi ngithatha lo muthi?

Akufanele ushayele noma usebenzise imishini lapho uqala ukuthatha lo muthi noma lapho umthamo wakho ulungiswa. I-Fentanyl ingabangela ukozela, isiyezi, nezikhathi zokuphendula ezihamba kancane, ezingenza ukushayela kube yingozi kuwe nakwabanye emgwaqeni.

Uma umzimba wakho usujwayele imithi futhi uqonda ukuthi ikuthinta kanjani, udokotela wakho angakusiza ukuthi unqume ukuthi kuphephile yini ukuqhubeka nokushayela. Abanye abantu bathola ukuthi bangashayela ngokuphepha ngenkathi bethatha imithamo ezinzile yalo muthi, kanti abanye badinga ukuhlela ezinye izindlela zokuthutha ngesikhathi sokwelashwa.