Fentanyl (indlela yempumulo)
Imikhiqizo etholakalayo
Lazanda
Mayelana naleli khambi
I-spray ye-fentanyl yempumulo isebenza ekwelapheni ubuhlungu obukhulu kubantu abane-kansa. Isebenza ebuhlungwini be-kansa obuqhumayo, okuyizikhathi zokwanda kobhlungu “oziqhumayo” ngemuva kokusetshenziswa kwemithi yobhlungu ejwayelekile. I-Fentanyl iyingxenye yeqembu lemithi ebizwa ngokuthi yi-opioid analgesics. Isebenza kuphela kubantu abase sebethatha i-opioid analgesics. I-Fentanyl isebenza ohlelweni oluphakathi lwemiyalo (CNS) ukuze ikhiphe ubuhlungu. Ezinye zezinto eziyisici zayo nazo zibangelwa imisebenzi e-CNS. Uma i-opioid isebenziwe isikhathi eside, ingaba yinto ebangela ukulutha (okubangela ukuncika ngokwengqondo noma ngokomzimba). Noma kunjalo, ngaphansi kokunakekelwa okuqinile kwesipheki sezokunakekelwa kwezempilo, abantu abanobuhlungu obuqhubekayo akufanele bavumele ukwesaba ukulutha kubavimbe ekusebenziseni i-opioids ukuze bakhiphe ubuhlungu babo. Ukuncika ngokwengqondo (ukulutha) kungenzeka kancane uma i-opioids isebenziselwa lesi sizathu. Ukuncika ngokomzimba kungabangela izimpawu zokuhoxa uma ukwelashwa kuphelile ngokuzumayo. Noma kunjalo, izimpawu zokuhoxa ezinzima ngokuvamile zingavimbeka ngokunciphisa umthamo kancane kancane phakathi nesikhathi ngaphambi kokuba ukwelashwa kuphele ngokuphelele. Udokotela wakho uzokuthatha lokhu ekubhekeni lapho enqoba ngesamba se-fentanyl yempumulo okufanele uyithole. Lolu lwemi ekutholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi TIRF (Transmucosal Immediate Release Fentanyl) REMS Program. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucineni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoyiletha. Lo ngumqulu ozothatha wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engaqondakali noma ebangelwa uketshezi kulo muthi noma kunoma iyiphi eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zoketshezi, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenamibhalo, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-fentanyl yasekhundleni kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-fentanyl yasekhundleni kubantu abadala. Noma kunjalo, abantu abadala bangase babe nomuzwa kakhulu wemiphumela ye-opioid analgesics kunabantu abadala abasebancane futhi banesikhathi esiningi sokuhlupheka yisifo sezinso esihambisana nobudala, okungase kudinge ukuqapha nokulungiswa komthamo kwabantu abamukela i-fentanyl yasekhundleni. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le miyekezo ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le miyekezo ngesikhathi sokuncelisa. Nakuba imithi ethile ingafanele isetshenziswe ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingase isetshenziswe ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingase zidingeke. Uma uthatha le miyekezo, kubalulekile ngokukhethekile ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le miyekezo nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale miyekezo noma ashintshe eminye imithi oyithathayo. Ukusebenzisa le miyekezo nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Imithi ethile akufanele isetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla ngoba ukuhlangana kungase kwenzeke. Ukusebenzisa utshwala noma utshako nanoma iyiphi imithi kungase futhi kubangele ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le miyekezo nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungakhuphuki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le miyekezo, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshako. Ukuba khona kwezinye izinkinga zezokwelapha kungase kuchaphazele ukusetshenziswa kwale miyekezo. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Sebenzisa le mishanguzo kuphela njengoba kunqunyiwe ngudokotela wakho. Ungayisebenzisi ngokweqile, ungayisebenzisi kaningi, futhi ungayisebenzisi isikhathi eside kunalokho okunqunyiwe ngudokotela wakho. I-Fentanyl nasal sprays iyasetshenziswa kubantu abakhuthazelela i-opioid kuphela. Uma ungaqiniseki ukuthi uyakhuthazelela i-opioid noma cha, xhumana nodokotela wakho ngaphambi kokusebenzisa le mishanguzo. Kubalulekile kakhulu ukuthi uqonde imithetho yenhlangano ye-TIRF REMS ukuvimbela ukulutha, ukusebenzisa kabi, nokusebenzisa kabi i-fentanyl. Lemishanguzo kufanele ifike ne-Medication Guide nemiyalo yomguli. Funda futhi ulandele le miyalo ngokucophelela. Funda futhi njalo lapho ugcwalisa iresiphi yakho uma kungenzeka kukhona ulwazi olusha. Buza udokotela wakho uma unemibuzo. Lemishanguzo iyasetshenziswa kuphela ekhaleni. Ungayifaki emehlweni akho noma ebusweni bakho. Uma ingena kulezi zindawo, geza ngamanzi ngokushesha. I-Fentanyl nasal spray isebenza ngokuhlukile kunamanye imikhiqizo ye-fentanyl, ngisho nasezingeni elifanayo. Ungayishintshi noma uyiguqulele kwamanye imikhiqizo equkethe i-fentanyl. Ukusebenzisa i-nasal spray: Uma kudingeka enye i-dose, linda okungenani amahora angu-2 ngaphambi kokwelapha enye ingxenye yobuhlungu obukhulu. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mishanguzo. I-dose yalemishanguzo izohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esembile. Ulwazi olulandelayo luhlanganisa kuphela i-doses ezingavamile yalemishanguzo. Uma i-dose yakho ihlukile, ungayishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemishanguzo oyithatha lixhomeke emandleni emishanguzo. Futhi, inani le-doses oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwe-doses, nobude besikhathi othatha imishanguzo kuya ngenkinga yezokwelapha oyisebenzisela imishanguzo. Gcina imishanguzo esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungayivumeli ukuba iqhwabe. Gcina ingafinyeleleki kubantwana. Ungagcini imishanguzo esidlulile noma imishanguzo engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahule kanjani imishanguzo oyisebenzisanga. Buza u-pharmacist wakho ngendlela engcono kakhulu yokulahla imishanguzo oyisebenzisanga. Lahla ibhodlela le-spray bese uqala ukusebenzisa elisha uma usebenzise i-sprays ezingama-8 noma uma sekudlule izinsuku ezingama-60 noma ngaphezulu kusukela esetshenziswe. Lahla noma yibaphi amabhodlela e-spray asebenzisiwe, asebenzisiwe ngokwengxenye, noma angadingeki ngokuthi ukhulule futhi uphucule isisombululo esisele esikhwameni. Ikhava evaliwe nebhodlela elingenalutho kufanele kubekwe esitsheni esivikelayo kubantwana ngaphambi kokulilahla ebhasikeni. Geza izandla zakho ngesepu namanzi ngokushesha ngemuva kokuphatha ikhava.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.