Fentanyl (indlela yokudlulisela ngolusu)
Imikhiqizo etholakalayo
Duragesic, Ionsys, APO-fentaYNL Matrix, CO fentaYNL, Mylan-fentaNYL Matrix Patch, Ran-fentaNYL Matrix, Ran-fentaNYL Transdermal System 100, Ran-fentaNYL Transdermal System 25, Ran-fentaNYL Transdermal System 50, Ran-fentaNYL Transdermal System 75, Sandoz fentaNYL Patch, Teva fentaNYL 100, Teva fentaNYL 12
Mayelana naleli khambi
Iphethini ye-Fentanyl yaseskin isebenza ekwelapheni ubuhlungu obukhulu, okuhlanganisa nobuhlungu obukhulu emva kokuthi kwenziwe i-opereyshini.I-Ionsys® ifakwa yisikhungo sakho sezempilo esibhedlela emva kokuthi kwenziwe i-opereyshini ukulawula ubuhlungu obukhulu isikhathi esifushane.I-Duragesic® isebenza ebuhlungwini obukhulu kangangokuthi kudinga ukunciphisa ubuhlungu ubusuku nemini isikhathi eside.Iphethini ye-Fentanyl yaseskin isebenza futhi ekwelapheni ubuhlungu obukhulu nobuhlala njalo obudinga isikhathi eside sokwelashwa futhi lapho eminye imithi yokuhlupheka ingasebenzi kahle ngokwanele noma ingakhuthaleki.Iphethini ye-Duragesic® yesikhumba akufanele isebenziswe uma udinga imithi yokuhlupheka isikhathi esifushane, njengoba kunjalo emva kokuthi kwenziwe i-opereyshini yezinyo noma i-tonsil.Ungayisebenzisi le phethini uma ubuhlungu bukhulu noma ubuhlungu obuvela ngezikhathi ezithile.IFentanyl iyilutho olukhulu lokuhlupheka (imithi yokuhlupheka).Isebenza ohlelweni oluphakathi lwezinzwa (CNS) ukuze inciphisa ubuhlungu.Uma imithi yokuhlupheka isebenziselwa isikhathi eside, ingaba yinto ebangela ukulutha, ibangele ukuncika ngokwengqondo noma ngokomzimba.Kodwa-ke, ngaphansi kokunakekelwa okuqinile kwesikhungo sezempilo, abantu abanobuhlungu obuqhubekayo akufanele bavumele ukwesaba ukulutha kubavimbe ekusebenziseni ama-opioids ukuze banciphise ubuhlungu babo.Ukuncika ngokwengqondo (ukulutha) kuncane kakhulu uma ama-opioids esetshenziswa ngenjongo.Ukuncika ngokomzimba kungabangela izimpawu zokuhoxa uma ukwelashwa kuphelile ngokuzumayo.Kodwa-ke, izimpawu ezinzima zokuhoxa zivame ukuvimbeka ngokunciphisa kancane inani lemithi isikhathi esithile ngaphambi kokuba ukwelashwa kuphele ngokuphelele.Lolu lwemi lapho lutholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi yi-Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.Lo mkhiqizo utholakala ngezindlela zokwelapha ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizokwenzeka. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqhelile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube yimanje azibonisi izinkinga ezikhethekile zezingane ezingalinda ukusetshenziswa kwe-Duragesic® patchne-Fentanyl extended-release patchezinganeni ezineminyaka emibili ubudala nangaphezulu. Kodwa-ke, iziguli ezingabantwana kufanele zibekezelele i-opioid ngaphambi kokusebenzisa i-fentanyl patch. Ukuphepha nokusebenza kahle akukaqiniswa ezinganeni ezineminyaka engaphansi kwemibili. Azikho izifundo ezifanele ezenziwe ngokuphathelene nobudala nokuthinta kwe-Ionsys® patchkubantu abasebancane. Ukuphepha nokusebenza kahle akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube yimanje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-fentanyl skin patch kubantu abadala. Kodwa-ke, iziguli ezikhulile zinezinkinga zokulala kakhulu nezinkinga zephunga, izinso, isibindi, noma inhliziyo ezihlobene nobudala, okungase kudinge ukunakekelwa nokulungiswa komthamo kwabantu abamukela i-fentanyl skin patch. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukuhlangana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izimithi ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla ngoba ukuhlangana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungase futhi kubangele ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungakugwemeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Udokotela wakho uyokutshela ukuthi usebenzise kangakanani le mishini futhi kaningi kangakanani. Umthamo wakho ungase udingeke ushintshwe izikhathi eziningi ukuze uthole ukuthi yini ephumelela kakhulu kuwe. Ungasebenzisi imishini eminingi noma uyisebenzise kaningi kunalokho udokotela wakho akutshela ukuba ukwenze. Uma kuthathwa imishini eminingi yalemi yisikhathi eside, ingase ibe yinto yokujwayela (ibangela ukuxhomeka kwengqondo noma emzimbeni). I-fentanyl skin patch isebenzelwa kuphela iziguli ezikhuthazelela i-opioid. Umgulisi uyakhuthazelela i-opioid uma i-opioids yomlomo isevele isetshenziswe ezinhlungwini ezinzima. Xhumana nodokotela wakho uma unemibuzo ngalokhu. Kubalulekile kakhulu ukuthi uqonde imithetho yohlelo lwe-Opioid Analgesic REMS ukuvimbela ukulutha, ukusebenzisa kabi, nokusebenzisa kabi i-fentanyl. Le mishini kufanele ifike ne-Medication Guide nemiyalo yomguli. Funda futhi ulandele le miyalo ngokucophelela. Funda futhi njalo lapho ugcwalisa iresiphi yakho uma kunemininingwane emisha. Buza udokotela wakho uma unemibuzo. Uzobamba i-Ionsys® patch ngenkathi ukhona esibhedlela. Usizi noma omunye ochwepheshe wezempilo oqeqeshwe uyokunika le mishini ngemuva kokuthi uqede ukuhlinzwa. Uzofundiswa ukuthi usebenzise kanjani le mishini esibhedlela, kodwa i-patch izosuswa yisikhungo sakho sezempilo ngaphambi kokuba ushiye esibhedlela. Ungashiyi esibhedlela ne-patch esikhunjeni sakho. Ukusebenzisa i-Duragesic® patch: Ukusebenzisa i-Fentanyl extended-release patch: Ezinganeni ezincane noma kubantu abane-mental alertness ephansi, i-Duragesic® patch kufanele ifakwe emuva phezulu ukuze kunciphise amathuba okuba i-patch isuswe futhi ifakwe emlonyeni. Ngemva kokuba i-Duragesic® patch ifakwe, i-fentanyl idlula esikhunjeni kancane kancane. Inani elithile lemishini kufanele lakheke esikhunjeni ngaphambi kokuba lithatheke emzimbeni. Kungenzeka kudlule usuku oluphelele (amahora angu-24) ngaphambi kokuba umthamo wokuqala uqale ukusebenza. Udokotela wakho angase adingeke alungise umthamo phakathi namasonto ambalwa okuqala ngaphambi kokuthola inani eliphumelela kakhulu kuwe. Ngisho noma uzizwa sengathi imishini ayisebenzi, ungawandisi inani le-fentanyl skin patch oyifakayo. Esikhundleni salokho, qala uqale uhlole nodokotela wakho. Cishe uzodinga ukuthatha i-opioid esebenza ngokushesha ngomlomo ukuze uphephe inhlungu phakathi nezinsuku ezimbalwa zokuqala zokusebenzisa i-fentanyl skin patch. Ungase futhi udinga enye i-opioid ngenkathi umthamo wakho we-fentanyl ulungiswa, futhi ukhulule noma iyiphi inhlungu "yokugqashula" eyenzeka kamuva. Qiniseka ukuthi awuthathi okuningi kwe-opioid enye, futhi ungayithathi kaningi kunalokho okuqondiswe. Ukuthatha i-opioids ezimbili ndawonye kungandisa amathuba ezingozi ezinkulu. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mishini. Umthamo walemi mishini uzobahlukile kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo elabelini. Ulwazi olulandelayo luhlanganisa kuphela imithamo yale mishini. Uma umthamo wakho uhlukile, ungawushintshi ngaphandle kokuthi udokotela wakho akutshele ukuba ukwenze. Inani lemishini oyithatha lixhomeke emandleni emishini. Futhi, inani lemithamo oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithamo, nobude besikhathi othatha imishini kuya ngenkinga yezokwelapha oyisebenzisela imishini. Uma ukhohlwa ukugqoka noma ushintshe i-patch, yifake ngokushesha okukhulu. Uma sekusondele isikhathi sokufaka i-patch yakho elandelayo, linda kuze kube yilapho ufake i-patch entsha bese ushiya leyo oyikhohliwe. Ungafaki ama-patches engeziwe ukuze uthole umthamo owukhohliwe. Susa i-Duragesic® patch izinsuku ezintathu (amahora angu-72) ngemuva kokuyifaka. Umhlinzeki wakho wezempilo uzosuswa i-Ionsys® patch ngaphambi kokuba ushiye esibhedlela. I-Ionsys® patch ayikho yokusetshenziswa ekhaya. Gcina imishini esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayeki. Gcina ingafinyeleleki ezinganeni. Ungagcini imishini esele iphelile noma imishini engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uphule kanjani noma iyiphi imishini ongayisebenzisi. I-Fentanyl ingabangela imiphumela engathandeki noma ukudlula ngokweqile uma ithathwe yizingane, izilwane ezifuywayo, noma abantu abadala abangajwayelene nemishini ebuhlungu ye-opioid eqinile. Qiniseka ukuthi ugcina imishini endaweni ephephile nevikelekile ukuvimbela abanye ukuyithola. Sebenzisa i-patch-disposal unit eyanikezwa nge-prescription yakho ukulahla ama-patches. Funda futhi ulandele imiyalo eprintiwe ku-disposal unit bese usebenzisa iyunithi elilodwa nge-patch ngayinye. Sula i-liner ye-disposal unit ukuze ubonise ubuso obunamathelayo. Faka uhlangothi olunamathelayo lwe-patch esetshenzisiwe ku-disposal unit bese uvala iphakheji yonke. Uma i-patch ingakaze isetshenziswe, iyikhulule esikhwameni bese ususa i-liner ehlanganisa uhlangothi olunamathelayo ngaphambi kokuyifaka ku-disposal unit. Phonsa i-disposal unit evaliwe ebhasikeni. Xoxa nomthengisi wemishini uma unemibuzo mayelana nendlela yokusebenzisa i-disposal unit. Ungaphuli i-pouch noma i-protective liner esithangathangeni. Zibeke ebhasikeni. Umhlinzeki wakho wezempilo uzoyilahla i-Ionsys® patch ngemuva kokuyisusa. Shiya noma iyiphi imishini ye-opioid engasetshenzisiwe endaweni yokuthatha imishini ngokushesha. Uma ungenayo indawo yokuthatha imishini eduze kwakho, phonsa noma iyiphi imishini ye-opioid engasetshenzisiwe esithangathangeni. Hlola esitolo sakho semishini sasekhaya nakwezinye izikhungo ukuze uthole izindawo zokuthatha imishini. Ungahlola futhi iwebhusayithi ye-DEA ukuze uthole izindawo. Nanka ikhonkco lewebhusayithi ye-FDA yokulahla imishini ngokuphepha: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.