Yini i-Fluticasone ne-Vilanterol: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Fluticasone ne-vilanterol kuyinhlanganisela yomuthi wokuphefumula osiza ukulawula isifuba somoya kanye nesifo sokuvinjelwa kwamaphaphu esingamahlalakhona (COPD). Lo muthi oqeda izinto ezimbili uhlanganisa i-corticosteroid (fluticasone) ne-bronchodilator esebenza isikhathi eside (vilanterol) ukunciphisa ukuvuvukala nokugcina imigudu yakho yomoya ivulekile ukuze kube lula ukuphefumula.

Ungase wazi lo muthi ngegama lawo lomkhiqizo i-Breo Ellipta. Yenzelwe njengomuthi wokwelapha owenziwa kanye ngosuku olusebenza ubusuku nemini ukusiza ukuvimbela izinkinga zokuphefumula ngaphambi kokuthi ziqale.

Yini i-Fluticasone ne-Vilanterol Esetshenziselwa Yona?

Le nhlanganisela yomuthi iphatha izimo ezimbili eziyinhloko zokuphefumula: isifuba somoya kubantu abadala nakubantu abasha abaneminyaka engu-18 nangaphezulu, kanye ne-COPD kubantu abadala. Ngesifuba somoya, sisiza ukuvimbela ukuhlaselwa futhi sinciphisa imvamisa yezimpawu ezinjengokukhwehlela, ukuphefumula kanzima, nokuqina kwesifuba.

Ezigulini ze-COPD, i-fluticasone ne-vilanterol zisiza ukuphatha izimpawu ze-bronchitis engamahlalakhona kanye ne-emphysema. Umuthi unciphisa ukuqubuka futhi wenza imisebenzi yansuku zonke ibe lula ngokugcina imigudu yakho yomoya ivuleke kakhulu futhi ingavuvukali.

Kubalulekile ukuqonda ukuthi lo ngumuthi wokulondoloza, hhayi i-inhaler yokuhlenga. Uzoyisebenzisa nsuku zonke ukuvimbela izimpawu, kodwa uzodinga i-inhaler yokusiza ngokushesha efana ne-albuterol ezimweni eziphuthumayo zokuphefumula.

Isebenza Kanjani i-Fluticasone ne-Vilanterol?

Lo muthi usebenza ngezindlela ezimbili ezihlukene kodwa ezigcwalisanayo. I-Fluticasone iyi-corticosteroid enciphisa ukuvuvukala emoyeni wakho, njengoba nje umuthi olwa nokuvuvukala unciphisa ukuvuvukala kwezinye izingxenye zomzimba wakho.

I-Vilanterol iyi-beta2-agonist esebenza isikhathi eside (LABA) ekhulula imisipha ezungeze imigudu yakho yomoya. Cabanga ngayo njengokusiza imigudu yakho yokuphefumula ihlale ivuleke kakhulu, okwenza kube lula ukuthi umoya ungene futhi uphume emaphashini akho.

Ngokuhlangene, lezi zithako ezimbili zenza inhlanganisela enamandla ebhekana nokuvuvukala kanye nokuncipha kwemisipha okwenza ukuphefumula kube nzima. Imiphumela ihlala amahora angama-24, yingakho udinga ukuyisebenzisa kanye ngosuku.

Lokhu kuthathwa njengomuthi onamandla ngokulinganisela. Unamandla kakhulu kunokusebenzisa i-corticosteroid yodwa kodwa awuqini kakhulu kunezinye izindlela zokwelapha ezihlanganisiwe ezidinga imithamo eminingi yansuku zonke.

Kufanele Ngiyithathe Kanjani I-Fluticasone ne-Vilanterol?

Thatha lo muthi kanye ngosuku ngesikhathi esifanayo, okungcono ekuseni. Akudingeki ukuthi uyithathe nokudla, futhi unga yisebenzisa esiswini esingenalutho ngaphandle kwezinkinga.

Umuthi uza nge-inhaler yempushana eyomile ebizwa nge-Ellipta. Ngemva kokuphefumula umthamo wakho, geza umlomo wakho kahle ngamanzi bese uwakhipha. Lesi sinyathelo esilula sisiza ekuvikeleni i-thrush, isifo sefungi esingathuthuka emlonyeni wakho ngenxa yokusetshenziswa kwe-corticosteroid.

Ngaphambi kokusebenzisa i-inhaler yakho, qiniseka ukuthi uyaqonda inqubo efanele. Bamba i-inhaler iqonde phezulu, shelelisa ikhava phansi uze uzwe ukuchofoza, phefumula ngokugcwele, bese ubeka izindebe zakho ngomlomo bese uphefumula okukodwa okunamandla, okujulile.

Ungalokothi usebenzise lo muthi ngaphezu kwesisodwa emahoreni angama-24, ngisho noma uzizwa sengathi udinga usizo olwengeziwe. Uma unezinkinga zokuphefumula ezingalawulwa ngumthamo wakho wansuku zonke, sebenzisa i-inhaler yakho yokuhlenga bese uthintana nomhlinzeki wakho wokunakekelwa kwezempilo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Fluticasone ne-Vilanterol?

Lokhu ngokuvamile kuwumuthi wesikhathi eside ozowusebenzisa izinyanga noma iminyaka, kuye ngesimo sakho. Abantu abaningi abane-asthma noma i-COPD badinga ukwelashwa okuqhubekayo ukuze bagcine izimpawu zabo zilawulwa kahle futhi bavimbele isimo sabo ukuthi singabi sibi.

Udktela wakho uzohlola njalo ukuthi umuthi usebenza kahle kangakanani kuwe. Bangase balungise umthamo wakho noma bakushintshele ekwelashweni okuhlukile uma izimpawu zakho zingalawulwa ngokwanele noma uma uhlangabezana nemiphumela engathandeki.

Ungayeki ukuthatha lo muthi kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Izimpawu zakho zokuphefumula cishe zizobuya, futhi ukuyeka kungazelelwe kungase kubangele ukuqubuka okukhulu kwesimo sakho.

Abanye abantu bangase bakwazi ukwehla baye emthomeni ophansi noma bashintshele emuthini ohlukile ngokuhamba kwesikhathi, kodwa lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngesiqondiso sezokwelapha esisekelwe ekutheni isimo sakho sesizinzile kangakanani.

Yini Imiphumela Eceleni ye-Fluticasone ne-Vilanterol?

Njengayo yonke imithi, i-fluticasone ne-vilanterol kungabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe uqiniseka kakhulu ngomuthi wakho.

Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi:

• Ikhanda
• Ukucasuka komphimbo noma umphimbo obuhlungu
• Izifo eziphezulu zokuphefumula ezifana nomkhuhlane
• I-thrush yomlomo (amaqhubu amhlophe emlonyeni wakho)
• Ukuminyana noma izinguquko zezwi
• Ukukhwehlela
• Ubuhlungu emhlane
• Ukuqunjelwa

Le miphumela emibi ejwayelekile ngokuvamile ayidingi ukunakekelwa kwezokwelapha ngaphandle kokuthi iba nzima noma iqhubeke. Ukugeza umlomo wakho ngemva kokusebenzisa ngakunye kunciphisa kakhulu ingozi yakho yokuthuthukisa i-thrush.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha. Lokhu kuhlanganisa izimpawu zokungezwani komzimba nezinto ezithile ezifana nokuqubuka, ukuluma, ukuvuvukala, isiyezi esikhulu, noma ubunzima bokuphefumula.

Abanye abantu bangase babe nemiphumela yenhliziyo nemithambo yegazi evela engxenyeni ye-vilanterol, okuhlanganisa ukwanda kwesilinganiso senhliziyo, ubuhlungu besifuba, noma ukuthuthumela. Nakuba lokhu kungavamile, kubalulekile ukukubika kudokotela wakho.

Ukusetshenziswa kwama-corticosteroids isikhathi eside ngezinye izikhathi kungaholela emiphumeleni engathi sína njengokwanda kwengozi yokutheleleka, ukuncipha kwamathambo, noma izinkinga ze-adrenal gland. Udokotela wakho uzokuqapha ukuze abone lezi zinkinga ezingavamile kodwa ezibalulekile ngesikhathi sokuhlolwa okuvamile.

Ubani Ongafanele Athathe I-Fluticasone ne-Vilanterol?

Lo muthi awulungelwe wonke umuntu, futhi izimo ezithile zempilo noma izimo zikwenza kungafaneleki noma kube yingozi. Ukuphepha kwakho kuyinto eza kuqala ekunqumeni ukuthi lo muthi ukufanele yini.

Akufanele usebenzise lo muthi uma unokungezwani komzimba ne-fluticasone, vilanterol, noma ezinye izithako ezikulo mithi. Abantu abanezinkinga ezinkulu zokungezwani komzimba namaprotheni obisi kufanele futhi bagweme lo muthi ngoba uqukethe i-lactose.

Le nhlanganisela ayivunyelwe ezinganeni ezingaphansi kweminyaka engu-18 zokwelashwa kwe-asthma. Nge-COPD, ihloselwe kuphela ukusetshenziswa ngabantu abadala. Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile, futhi udokotela wakho uzoqondanisa izinzuzo nezingozi ezingaba khona.

Abantu abanezimo ezithile zenhliziyo badinga ukuqapha okwengeziwe ngoba i-vilanterol ingathinta isigqi senhliziyo nomfutho wegazi. Lokhu kuhlanganisa labo abanokushaya kwenhliziyo okungajwayelekile, umfutho wegazi ophezulu, noma isifo semithambo yenhliziyo.

Uma unezifo ezisebenzayo, ikakhulukazi izifo zama-fungal, udokotela wakho angase afune ukuzelapha ngaphambi kokuqala lo muthi. Ingxenye ye-corticosteroid ingenza kube nzima ukuthi umzimba wakho ulwe nezifo.

Izinkinga zesibindi zingathinta indlela umzimba wakho oqhubula ngayo lo muthi, ngakho-ke abantu abanokukhubazeka kwesibindi bangase badinge ukulungiswa komthamo noma ukwelashwa okuhlukile.

Amagama Omkhiqizo we-Fluticasone ne-Vilanterol

Igama eliyinhloko lomkhiqizo walo muthi ohlanganisiwe yi-Breo Ellipta, ekhiqizwa yi-GlaxoSmithKline. Le yindlela etholakala kakhulu futhi yilena ozohlangana nayo kakhulu ekhemisi lakho.

I-Breo Ellipta iza ngedivayisi yokuphefumula eyomile enombala oluhlaza okwesibhakabhaka nokubomvu. Umuthi uyatholakala ngamandla ahlukene, udokotela wakho ekhetha umthamo ofanele ngokuya ngesimo sakho esithile nobukhulu bezimpawu.

Ngenkathi izinhlobo ezivamile zingase zitholakale esikhathini esizayo, okwamanje i-Breo Ellipta iyibhrendi enkulu etholakala ezimakethe eziningi. Umshwalense wakho kanye nekhemisi kungase kuthinte umkhiqizo othile owutholayo, kodwa izithako ezisebenzayo zihlala zinjalo.

Ezinye izindlela ze-Fluticasone ne-Vilanterol

Ezinye izinketho zemithi ziyatholakala uma i-fluticasone ne-vilanterol kungafaneleki kuwe. Udokotela wakho angakusiza ukuthi uhlole lezi ezinye izindlela ngokusekelwe ezimpawini zakho ezithile, umlando wezokwelapha, kanye nemigomo yokwelashwa.

Ezinye iziphefumulisi ezihlanganisiwe zihlanganisa i-fluticasone ne-salmeterol (Advair), i-budesonide ne-formoterol (Symbicort), kanye ne-mometasone ne-formoterol (Dulera). Ngayinye yalezi zinhlanganisela isebenza ngendlela efanayo kodwa ingase ibe nezinhlelo zokulinganisa ezihlukene noma amaphrofayili emiphumela emibi.

Kubantu abakhetha imithi ehlukene, ungasebenzisa isiphefumulisi se-corticosteroid njenge-fluticasone (Flovent) kanye ne-bronchodilator ehlukile esebenza isikhathi eside. Le ndlela ivumela ukulinganisa okwenzelwe umuntu ngamunye kodwa idinga ukusebenzisa iziphefumulisi ezimbili ezihlukene.

Abanye abantu benza kahle ngemithi ye-corticosteroid kuphela, ikakhulukazi uma isimo sabo singokuvuvukala kunokuthi sihilele ukuncipha kwemisipha okukhulu. Abanye bangazuza emakilasini emithi amasha njenge-leukotriene modifiers noma ukwelashwa kwe-biologic.

Enye indlela engcono kakhulu incike ohlotsheni lwakho oluthile lwe-asthma noma i-COPD, okuthandayo ukuphila kwakho, nokuthi ube ngcono kangakanani ekwelashweni kwangaphambilini. Umhlinzeki wakho wezempilo uzosebenza nawe ukuthola inketho esebenza kahle kakhulu.

Ingabe i-Fluticasone ne-Vilanterol ingcono kune-Advair?

Kokubili i-fluticasone/vilanterol (Breo Ellipta) kanye ne-fluticasone/salmeterol (Advair) kuyizindlela zokwelapha ezihlanganisiwe ezisebenzayo, kodwa zinezinye izinto eziyinhloko ezihlukile ezingenza enye ifaneleke kakhulu kuwe kunenye.

Inzuzo enkulu ye-Breo Ellipta ukuhlelelwa kwayo kokuthatha umuthi kanye ngosuku, uma kuqhathaniswa nesidingo se-Advair sokuthatha kabili ngosuku. Lokhu kungathuthukisa kakhulu ukunamathela emithini futhi kwenze inqubo yakho yokwelapha ibe lula futhi ilunge.

I-Breo Ellipta iphinde itholakale nge-inhaler yomuthi owomile ongadingi ukuxhumana phakathi kokucindezela nokuphefumula, ngokungafani ne-Advair HFA. Abantu abaningi bathola ukuthi idivayisi ye-Ellipta kulula ukuyisebenzisa ngendlela efanele, okungathuthukisa ukuthi kungakanani umuthi ngempela ofinyelela emaphashini akho.

Nokho, i-Advair isitholakala isikhathi eside futhi inemininingwane ebanzi yokuphepha yesikhathi eside. Abanye abantu futhi basabela kangcono ku-salmeterol (ku-Advair) kunaku-vilanterol (ku-Breo Ellipta), nakuba kokubili kuyi-bronchodilators esebenza isikhathi eside.

Ukukhetha phakathi kwale mithi kuvame ukuncika ezintweni ozithandayo zokuphila, ukumbozwa komshuwalense, nokuthi usabela kahle kangakanani enkokhethweni ngayinye. Udokotela wakho angakusiza ukuthi unqume ukuthi iyiphi inhlanganisela engasebenza kangcono esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Fluticasone kanye ne-Vilanterol

Ingabe i-Fluticasone kanye ne-Vilanterol iphephile ezigulini zenhliziyo?

Abantu abanezifo zenhliziyo bangasebenzisa lo muthi ngokuphepha, kodwa kudinga ukuqapha okucophelelayo nokucatshangelwa kwesimo sakho senhliziyo esithile. Ingxenye ye-vilanterol ingathinta izinga lenhliziyo kanye nesigqi, yingakho udokotela wakho edinga ukwazi nganoma yiziphi izinkinga zenhliziyo.

Uma unezifo zenhliziyo ezilawulwa kahle, udokotela wakho angase anqume ukuthi izinzuzo zokulawula kangcono ukuphefumula zidlula izingozi zenhliziyo nemithambo yegazi. Cishe bazoqala ngomthamo ophansi osebenzayo futhi bakuqaphele eduze nganoma yiziphi izifo ezingahle zibe khona ezihlobene nenhliziyo.

Kodwa-ke, uma unesifo senhliziyo esingazinzile, ukuhlaselwa yinhliziyo kwamuva, noma ama-arrhythmias abucayi, udokotela wakho angase ancome ukwelashwa okuhlukile okungenawo ama-bronchodilators asebenza isikhathi eside. Hlala uxoxa ngomlando wakho ophelele wenhliziyo nomhlinzeki wakho wezempilo.

Kufanele Ngenzeni Uma Ngisebenzisa Ngengozi I-Fluticasone Ne-Vilanterol Engaphezu Kakhulu?

Uma ngengozi uthatha ngaphezu komthamo wakho obekiwe, ungangeni ekuqhumeni, kodwa ziqaphele ngokucophelela imiphumela emibi. Xhumana nodokotela wakho noma ekhemisi ukuze uthole isiqondiso, ikakhulukazi uma usebenzise okuningi kakhulu kunokunconywe.

Qaphela izimpawu zokweqisa umthamo, ezingase zihlanganise ukushaya kwenhliziyo okusheshayo, ukuthuthumela, ikhanda elibuhlungu, noma ukuzizwa unovalo. Lezi zimpawu zenzeka ngoba i-vilanterol eningi kakhulu ingase iqhubeke nokukhuthaza uhlelo lwakho lwe-cardiovascular.

Ungazami ukuthi "weqe" umthamo wakho olandelayo ukuze ubuyisele imithi eyengeziwe. Kunalokho, buyela esimisweni sakho esivamile sokulinganisa futhi uxoxe ngalesi sigameko nomhlinzeki wakho wezempilo ekuqokweni kwakho okulandelayo.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Fluticasone Ne-Vilanterol?

Uma ukhohlwa umthamo wakho wansuku zonke, wuthatha ngokushesha lapho ukhumbula, kodwa kuphela uma kusewusuku olufanayo. Uma sekuyisikhathi somthamo wakho olandelayo noma ukhumbula ngosuku olulandelayo, weqa umthamo ophuthelwe bese ubuyela esimisweni sakho esivamile.

Ungalokothi uthathe imithamo emibili ngosuku olulodwa ukuze ubuyisele umthamo ophuthelwe. Lokhu kungaholela ezimpawini zokweqisa umthamo futhi ngeke kunikeze ukulawula okungcono kwezimpawu zakho zokuphefumula.

Ukuphuthelwa imithamo ngezikhathi ezithile ngeke kubangele izinkinga ngokushesha, kodwa zama ukugcina ukuqina ukuze uthole ukulawula okungcono kakhulu kwezimpawu. Cabangela ukusetha isikhumbuzi sansuku zonke ocingweni lwakho noma ukuxhumanisa imithi yakho nesimiso sansuku zonke njengokuxubha amazinyo akho.

Ngingayeka Nini Ukuthatha I-Fluticasone Ne-Vilanterol?

Kufanele uyeke kuphela ukuthatha lo muthi ngaphansi kokuqondiswa kwezokwelapha, ngisho noma uzizwa ungcono kakhulu. Isifuba somoya kanye ne-COPD yizimo ezingamahlala-khona ezivame ukudinga ukwelashwa okuqhubekayo ukuze kulawulwe kahle.

Udokotela wakho angase acabange ukunciphisa umthamo wakho noma ashintshe imithi uma izimpawu zakho zikwazi ukulawulwa kahle isikhathi eside. Le nqubo, ebizwa ngokuthi "ukwehla," yenziwa kancane kancane ukuze kuqinisekiswe ukuthi izimpawu zakho azibuyi.

Abanye abantu bangase bakwazi ukuyeka lo muthi uma isimo sabo sithuthuka kakhulu noma uma bedlulela kwenye indlela yokwelapha. Kodwa-ke, lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngokubambisana nomhlinzeki wakho wezempilo ngokusekelwe ekuhlolweni komsebenzi wamaphaphu akho kanye namaphethini ezimpawu.

Ngingawusebenzisa Lo Muthi Ngesikhathi Ngikhulelwe?

Ukukhulelwa kudinga ukucatshangelwa okukhethekile uma usebenzisa noma yimuphi umuthi, okuhlanganisa i-fluticasone ne-vilanterol. Ngenkathi isifuba somoya esingalawulwa sibeka izingozi kumama nomntwana, imiphumela yemithi nayo idinga ukuhlolwa ngokucophelela.

Udokotela wakho uzolinganisela izinzuzo zokugcina ukulawulwa okuhle kwesifuba somoya ngokumelene nanoma yiziphi izingozi ezingase zibe khona kumntwana wakho osakhula. Ezimweni eziningi, izinzuzo zokuvimbela ukuhlaselwa okukhulu kwesifuba somoya zidlula izingozi zemithi.

Uma uhlela ukukhulelwa noma uthola ukuthi ukhulelwe ngenkathi uthatha lo muthi, xoxa ngohlelo lwakho lokwelashwa nomhlinzeki wakho wezempilo ngokushesha. Bangase balungise umthamo wakho, bakushintshele kwenye imithi, noma baqhubeke nokwelashwa kwakho kwamanje ngokubheka eduze.