Yini i-Gadodiamide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Gadodiamide iyisithako esihlukile esifakwa odokotela emithanjeni yakho ukusiza ukudala izithombe ezicacile, ezinemininingwane eminingi ngesikhathi sokuskena kwe-MRI. Cabanga ngayo njengedayi ekhethekile egqamisa izingxenye ezithile zomzimba wakho, okwenza kube lula eqenjini lakho lezokwelapha ukubona ukuthi kwenzekani ngaphakathi futhi likunikeze ukunakekelwa okungcono kakhulu.

Lo muthi ungoweqembu elibizwa ngokuthi ama-ejenti ahlukile asekelwe ku-gadolinium. Ngenkathi igama lingase lizwakale liyinkimbinkimbi, i-gadodiamide imane nje isiza udokotela wakho ukuthi abuke kangcono izitho zakho, imithambo yegazi, nezicubu ngesikhathi sokuhlolwa kokucabanga.

Yini i-Gadodiamide Esetshenziselwa Yona?

I-Gadodiamide isiza odokotela ukuthi babone ngaphakathi emzimbeni wakho ngokusobala ngesikhathi sokuskena kwe-MRI. Lesi sithako esihlukile sisebenza njengomgqamisi, senza izicubu ezithile nemithambo yegazi ivele ngemuva.

Udokotela wakho angase ancome i-gadodiamide lapho kudingeka ukuthi bahlole ubuchopho bakho, umgogodla, noma ezinye izingxenye zomzimba wakho ngezinkinga ezingaba khona. Ilusizo ikakhulukazi ekutholeni izimila, izifo, ukuvuvukala, noma ukungajwayelekile kwemithambo yegazi okungenzeka kungaveli ngokusobala ku-MRI ejwayelekile.

Lo muthi usetshenziselwa futhi ukuhlola ukuthi izinso zakho zisebenza kahle kangakanani nokuhlola ukuvaleka kwemithambo yakho yegazi. Ngezinye izikhathi odokotela bayawusebenzisa ukuze babone kangcono inhliziyo yakho noma bahlole izicubu ezilimele ngemva kokuhlinzwa.

Isebenza Kanjani i-Gadodiamide?

I-Gadodiamide ithathwa njenge-ejenti ehlukile elinamandla aphakathi nendawo esebenza ngokushintsha indlela ama-molecule amanzi aziphatha ngayo eduze kwayo ngesikhathi sokuskena kwe-MRI. Uma ifakwe emgudwini wakho wegazi, ihamba emzimbeni wakho wonke futhi ishintsha okwesikhashana izakhiwo kazibuthe zezicubu eziseduze.

Lolu shintsho lwenza izindawo ezithile zivele zikhanye noma zibe mnyama ezithombeni ze-MRI, okudala umehluko ongcono phakathi kwezinhlobo ezahlukene zezicubu. Izinso zakho ngokwemvelo zihlunga umuthi ngaphandle kwesistimu yakho, ngokuvamile kungakapheli amahora angama-24 kuya kwangama-48 ngemva komjovo.

Lonke le nqubo yenzelwe ukuba ibe yesikhashana futhi iphephe kubantu abaningi. Umzimba wakho uphatha i-gadodiamide njengento engajwayelekile edinga ukususwa, okuyilokho kanye okufanele kwenzeke.

Ngingayithatha kanjani i-Gadodiamide?

I-Gadodiamide inikezwa kuphela ochwepheshe bezempilo ngomjovo we-intravenous (IV), ngokuvamile esibhedlela noma esikhungweni sokuthwebula izithombe. Akudingeki ukuthi wenze lutho olukhethekile ukulungiselela umjovo ngokwawo.

Ngaphambi kokuhlangana kwakho, ungaqhubeka udla futhi uphuze ngendlela ejwayelekile ngaphandle uma udokotela wakho ekunikeza imiyalelo ethile ngenye indlela. Ezinye izindawo zingase zikucele ukuthi ugweme ukudla amahora ambalwa ngaphambi kokuskena, kodwa lokhu kuyahluka ngokuya ngendawo yomzimba wakho ehlolwayo.

Umjovo ngokuvamile uthatha imizuzwana embalwa nje, futhi uzowuthola ngenkathi ulele etafuleni le-MRI. Uchwepheshe oqeqeshiwe noma umhlengikazi uzofaka umugqa omncane we-IV engalweni yakho bese ejova i-ejenti yokuqhathanisa ngesikhathi esifanele ngesikhathi sokuskena kwakho.

Ungase uzwe umuzwa opholile noma ukucindezela okuncane lapho umuthi ungena egazini lakho, kodwa lokhu kujwayelekile ngokuphelele futhi ngokuvamile kudlula ngokushesha.

Ngingayithatha isikhathi esingakanani i-Gadodiamide?

I-Gadodiamide ngumjovo owodwa onikezwa kuphela ngesikhathi sokuqokwa kwakho kwe-MRI. Awuyithathi ekhaya noma uqhubeke uyisebenzisa ngemuva kokuthi ukuskena kwakho kuqediwe.

Umuthi usebenza ngokushesha uma usujovwe futhi uqala ukushiya umzimba wakho kungakapheli amahora ambalwa. Abantu abaningi basusa i-ejenti yokuqhathanisa ngokuphelele phakathi nosuku olulodwa kuya kwamabili ngomsebenzi ojwayelekile wezinso.

Uma udinga ukuskena okwengeziwe kwe-MRI esikhathini esizayo, udokotela wakho uzoqoka ukuthi ngabe udinga omunye umthamo we-gadodiamide ngokuya ngalokho abakufunayo kanye nesimo sakho sempilo.

Yiziphi Imiphumela Eceleni ye-Gadodiamide?

Abantu abaningi bayayibekezelela kahle i-gadodiamide, nabaningi abangabi nayo imiphumela emibi nhlobo. Kodwa-ke, kuyasiza ukwazi ukuthi yini ongayilindela ukuze uzizwe ulungile futhi unolwazi.

Imiphumela emibi evame kakhulu ngokuvamile imnene futhi yesikhashana. Nakhu okuhlangenwe nakho kwabanye abantu:

• Ukucasuka okuncane noma ukuzwa sengathi uyagula kancane
• Ukunambitheka kwensimbi emlonyeni wakho okuvame ukunyama ngokushesha
• Isiyezi esincane noma ukukhathala
• Ukufudumala noma ukupholisa endaweni yokujova
• Ikhanda elincane

Lezi zimpendulo ngokuvamile zizixazulula zodwa phakathi namahora ambalwa futhi azidingi ukwelashwa okukhethekile.

Imiphumela emibi engavamile kodwa ebonakalayo ingabandakanya ukuhlanza, imihuzuko, noma ukuluma. Ngenkathi lokhu kungase kuzizwe kungakhululekile, ngokuvamile kulawuleka futhi ithimba lakho lezokwelapha liyazi ukuthi lingakusiza kanjani.

Izimpendulo ezinzima zokungezwani komzimba zingavamile kodwa zingenzeka. Ithimba lakho lokunakekelwa kwezempilo lizokuqapha ngesikhathi nangemva komjovo nganoma yiziphi izimpawu zenkinga, njengobunzima bokuphefumula, ukuvuvukala okukhulu, noma izinguquko ezinkulu emfutheleni wegazi.

Kukhona nesimo esingavamile esibizwa ngokuthi i-nephrogenic systemic fibrosis (NSF) engathinta abantu abanezinkinga ezinzima zezinso. Yingakho udokotela wakho ezohlola ukusebenza kwezinso zakho ngaphambi kokukunika i-gadodiamide uma benokukhathazeka.

Ubani Ongafanele Athole I-Gadodiamide?

I-Gadodiamide ayilungile kuwo wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyincoma. Okukhathazayo okuyinhloko ukusebenza kwezinso, ngoba izinso zakho zidinga ukuhlunga imithi ngaphandle kwesistimu yakho.

Abantu abanezifo ezinzima zezinso noma ukuhluleka kwezinso ngokuvamile akufanele bathole i-gadodiamide ngoba izinso zabo zingase zingakwazi ukuyiqeda ngempumelelo. Lokhu kungaholela ezinkingeni, ngakho-ke udokotela wakho cishe uzo-oda ukuhlolwa kwegazi ukuze ahlolisise ukusebenza kwezinso zakho kuqala.

Uma uke waba nokusabela okukhulu komzimba ku-gadodiamide noma ezinye izinto eziphikisana ne-gadolinium-based contrast agents esikhathini esidlule, udokotela wakho cishe uzokhetha indlela ehlukile yezidingo zakho zokuthwebula izithombe.

Abesifazane abakhulelwe ngokuvamile bayakugwema ukusebenzisa i-gadodiamide ngaphandle uma izinzuzo zicacile ukuthi zidlula izingozi, njengoba kungekho ucwaningo olwanele oluqinisekisa ukuthi iphephile ngokuphelele ngesikhathi sokukhulelwa. Udokotela wakho uzoxoxa ngezindlela ezingenye uma ukhulelwe noma ungase ukhulelwe.

Abantu abanezimo ezithile zenhliziyo noma isifuba esikhulu somoya bangase badinge izinyathelo zokuphepha ezikhethekile, kodwa lokhu akusho ukuthi ngeke bakwazi ukuthola i-ejenti yokuqhathanisa. Ithimba lakho lezokwelapha lizohlola izinzuzo nezingozi zesimo sakho esithile.

Amagama Omkhiqizo we-Gadodiamide

I-Gadodiamide itholakala ngaphansi kwegama lomkhiqizo elithi Omniscan emazweni amaningi. Leli yigama okungenzeka ukuthi uzolibona emarekhodini akho ezokwelapha noma emaphepheni okukhishwa.

Ezinye izikhungo zingase zibhekisele kuyo ngokuthi “i-MRI contrast” noma “i-gadolinium contrast” ekuxhumaneni kwazo nawe. Wonke la magama abhekisela ohlotsheni olufanayo lwemithi, nakuba ukwakheka okuthile kungase kuhluke kancane.

Lapho uhlela i-aphoyintimenti yakho noma uxoxa ngenqubo nodokotela wakho, ungasebenzisa igama elivamile (gadodiamide) noma igama lomkhiqizo (Omniscan) futhi bazokwazi kahle ukuthi ukhuluma ngani.

Ezinye Izindlela Zokusebenzisa i-Gadodiamide

Ezinye izinto zokuqhathanisa zingahlinzeka ngezinzuzo ezifanayo uma i-gadodiamide ingakulungele. Udokotela wakho angase ancome i-gadoterate meglumine, i-gadobutrol, noma i-gadoxetic acid kuye ngokuthi badinga ukuhlola ini.

Ngayinye enye indlela inezakhiwo ezihlukile kancane kanye namaphethini okususwa, okusho ukuthi udokotela wakho angakhetha inketho engcono kakhulu yesimo sakho sezokwelapha esithile kanye nomsebenzi wezinso.

Kwezinye izimo, udokotela wakho angase anqume ukwenza i-MRI ngaphandle kwanoma iyiphi i-ejenti yokuqhathanisa. Nakuba lokhu kungase kunikeze izithombe ezinganemininingwane eminingi ezimweni ezithile, kungase kusahlinzeka ngolwazi olubalulekile ngempilo yakho.

Kulabo bantu abangakwazi ukuthola noma yimaphi ama-ejenti ahlukile asekelwe ku-gadolinium, ezinye izindlela zokuthwebula izithombe ezinjenge-CT scans ezinamanye amamathiriyali ahlukile noma i-ultrasound zingase zibe ezinye izindlela ezifanele.

Ingabe i-Gadodiamide Ingcono Kunezinye Izinto Ezingafani?

I-Gadodiamide isebenza kahle ngezinhloso eziningi zokuthwebula izithombe, kodwa ukuthi ingabe “ingcono” kuncike ezidingweni zakho ngazinye kanye nesimo sakho sezokwelapha. Ama-ejenti ahlukile ahlukile anezinto ezihlukene eziqinile futhi afaneleka ezinhlotsheni ezihlukene zokuhlolwa.

Ezinye izinto ezintsha ezingafani zikhishwa emzimbeni ngokushesha noma zibe namaphrofayili ahlukene okuphepha, okungenzeka ukuthi kuzenzele izinqumo ezingcono kubantu abathile. Udokotela wakho ucabangela izinto ezinjengomsebenzi wakho wezinso, indawo ehlolwayo, kanye nanoma yiziphi izindlela ozitholile ngaphambilini.

I-ejenti “engcono” ehlukile imane nje yileyo ephephe kakhulu futhi esebenza kahle esimweni sakho esithile. Ithimba lakho lezokwelapha linolwazi ngezinketho ezihlukahlukene futhi lizokhetha leyo ebanika ulwazi abaludingayo ngenkathi ikugcina ukhululekile ngangokunokwenzeka.

Imibuzo Evame Ukubuzwa Mayelana ne-Gadodiamide

Ingabe i-Gadodiamide iphephile kubantu abanesifo sikashukela?

I-Gadodiamide ngokuvamile iphephile kubantu abanesifo sikashukela, kodwa udokotela wakho uzonaka kakhulu umsebenzi wakho wezinso ngaphambi kokukunika i-ejenti ehlukile. Isifo sikashukela singathinta impilo yezinso ngokuhamba kwesikhathi, ngakho-ke ithimba lakho lezokwelapha lizokwenza izivivinyo zegazi ukuze liqinisekise ukuthi izinso zakho zisebenza kahle ngokwanele ukucubungula umuthi.

Uma uthatha i-metformin yesifo sikashukela, udokotela wakho angase akucele ukuthi uyeke ukuyithatha usuku noma ezimbili ngesikhathi se-MRI yakho. Lokhu kumane nje kuyisinyathelo sokuzivikela ukuvimbela noma yikuphi ukusebenzisana okungase kube khona, futhi uzokwazi ukuqhubeka nohlelo lwakho olujwayelekile lwemithi ngemva kwalokho.

Ngingenzani uma ngithola i-Gadodiamide eningi ngengozi?

Ochwepheshe bezempilo babala ngokucophelela futhi balinganise imithamo ye-gadodiamide, ngakho ukweqisa ngengozi akuvamile kakhulu. Inani olitholayo lincike esisindweni somzimba wakho kanye nohlobo lokuskena olwenziwayo.

Uma ukhathazekile ngomthamo owutholile, unganqikazi ukukhuluma nethimba lakho lezokwelapha ngokushesha. Bangakwazi ukubukeza ishadi lakho futhi banikeze ukuqinisekiswa ngokufaneleka komthamo wakho. Esimeni esingavamile sokweqisa, ithimba lakho lezokwelapha liyazi ukuthi lingakuqapha kanjani futhi linikeze ukunakekelwa okusekelayo ngenkathi izinso zakho ziqeda umuthi owedlulele.

Kufanele Ngenzeni Uma Ngingaphuthelwa Umthamo We-Gadodiamide?

Njengoba i-gadodiamide inikezwa kanye kuphela ngesikhathi sokuqokwa kwakho kwe-MRI, awukwazi ngempela ukuphuthelwa umthamo ngomqondo wendabuko. Uma ukuqokwa kwakho kwe-MRI kukhanselwa noma kuhlelwa kabusha, uzothola nje i-ejenti yokuqhathanisa ngesikhathi sakho sokuqokwa esisha.

Uma kudingeke ukuthi uhambe ngaphambi kokuqeda i-MRI yakho nganoma yisiphi isizathu, xhumana nehhovisi likadokotela wakho noma isikhungo sokuthwebula izithombe ukuze uxoxe ngokuhlela kabusha. Bazonquma ukuthi ngabe udinga ukuphinda umjovo wokuqhathanisa noma ngabe bathole izithombe ezanele zokwenza ukuxilongwa.

Ngingayeka Nini Ukuthatha I-Gadodiamide?

Akudingeki ukuthi “uyeke” ukuthatha i-gadodiamide ngoba akuyona imithi eqhubekayo. Umzimba wakho ngokwemvelo uyayiqeda phakathi nosuku olulodwa noma ezimbili ngemuva kokuskena kwakho kwe-MRI, ngakho-ke akukho okudingeka ukwenze ukuze uyeke.

Ungabuyela kuyo yonke imisebenzi yakho ejwayelekile ngokushesha ngemuva kwe-MRI yakho ngaphandle kokuthi udokotela wakho akunikeze imiyalelo ethile ngenye indlela. I-ejenti yokuqhathanisa izosuka ohlelweni lwakho yodwa ngomsebenzi ojwayelekile wezinso nokuchama.

Ngingashayela Ngemuva Kokuthola I-Gadodiamide?

Abantu abaningi bangashayela ngokujwayelekile ngemuva kokuthola i-gadodiamide, ngoba ngokuvamile ayibangeli ukozela noma iphazamise ikhono lakho lokusebenzisa imoto. Kodwa-ke, uma uzizwa unesiyezi, unesiyezi, noma ngaphandle kwalokho ungazizwa kahle ngemuva komjovo wakho, kungcono ukuthi omunye umuntu akuqhubele ekhaya.

Abanye abantu bazizwa bekhathele kancane ngemva kwe-MRI ngenxa yokucindezeleka kwenqubo uqobo kunokuba ngenxa yomuthi ohlukile. Thembela emzimbeni wakho futhi ungashayeli uma ungezwa uqaphile ngokuphelele futhi ukhululekile ngemuva kwesondo.