Kuyini Ukujova i-Glucagon: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

Ukujova i-Glucagon ngumuthi osindisa impilo okhuphula ngokushesha amazinga kashukela egazini ngesikhathi se-hypoglycemia enzima (ushukela wegazi ophansi ngendlela eyingozi). Le hormone isebenza njengohlelo lwakho lomzimba lokuphendula eziphuthumayo, ikhipha ngokushesha ushukela ogcinwe esibindini sakho uma uwudinga kakhulu.

Cabanga nge-glucagon njengeqembu lakho lokuhlenga i-glucose elakhelwe ngaphakathi emzimbeni wakho. Lapho ushukela wegazi wehla emazingeni ayingozi futhi ungenakudla noma ukuphuza, lokhu kujova kungena ukuvimbela izinkinga ezinkulu njengokuthuthumela noma ukulahlekelwa ukwazi.

Kuyini Ukujova i-Glucagon?

Ukujova i-Glucagon kuyinguqulo yokwenziwa ye-hormone i-pancreas yakho ekhiqiza ngokwemvelo. Yenzelwe ngqo izimo eziphuthumayo lapho othile onesifo sikashukela ezwa ushukela wegazi ophansi kakhulu futhi engakwazi ukudla noma ukuphuza ngokuphepha.

Lo muthi uza ngamapeni agcwaliswe ngaphambilini, ama-auto-injectors, noma izinhlobo zempushana ezidinga ukuxutshwa ngaphambi kokusetshenziswa. Ukujova kusebenza ngemizuzu ukukhulisa amazinga e-glucose yegazi, okwenza kube yithuluzi elibalulekile eliphuthumayo kubantu abanesifo sikashukela nemindeni yabo.

Ngokungafani nemithi ejwayelekile yesifo sikashukela eyehlisa ushukela wegazi, i-glucagon yenza okuphambene. Itshela isibindi sakho ukuthi sikhiphe i-glucose egciniwe egazini lakho, inikeze ukukhushulwa kwamandla okusheshayo umzimba wakho owudinga ngokuphuthumayo ngesikhathi esiphuthumayo se-hypoglycemic.

Isetshenziselwani Ukujova i-Glucagon?

Ukujova i-Glucagon kulapha ukwelapha i-hypoglycemia enzima lapho othile engakwazi ukudla noma ukuphuza ukuze akhulise ushukela wegazi lakhe ngokuphepha. Lokhu kuvame ukwenzeka lapho amazinga e-glucose yegazi ehluleka ngaphansi kuka-70 mg/dL futhi umuntu engazi, enokuthuthumela, noma engakwazi ukugwinya.

Lo muthi unqunyelwe ikakhulukazi abantu abanesifo sikashukela sohlobo 1, nakuba labo abanesifo sikashukela sohlobo 2 abasebenzisa i-insulin nabo bangase bayidinge. Kubaluleke kakhulu kubantu ababa neziqephu ezivamile zoshukela wegazi ophansi noma abanomlando wokuphendula okunzima kwe-hypoglycemic.

Abahlinzeki bezempilo nabo basebenzisa imijovo ye-glucagon ezindaweni zezokwelapha ngenjongo yokwenza izinqubo zokuxilonga. Ngesikhathi sokuhlolwa okuthile okufana ne-CT scans yesisu, i-glucagon isiza ukuphumuza imisipha yamathumbu ukuze kutholakale izithombe ezicacile.

Isebenza Kanjani I-Glucagon Injection?

I-Glucagon injection isebenza ngokubopha kuma-receptors athile esibindini sakho, okwenza ukuthi kuphulwe ngokushesha i-glucose egciniwe ebizwa nge-glycogen. Le nqubo, eyaziwa ngokuthi i-glycogenolysis, ikhipha i-glucose ngqo emithanjeni yakho yegazi ngemizuzu engu-5-10 ngemuva komjovo.

Lo muthi uthathwa njengokwelashwa okuqinile nokusebenza ngokushesha eziphuthumayo. Ngokungafani nokwelashwa okusebenza kancane, i-glucagon ayinciki ohlelweni lwakho lokugaya ukudla ukuthi lusebenze. Idlula isisu ngokuphelele, okwenza isebenze ngisho nalapho umuntu engazi lutho noma ehlanza.

Umjovo futhi uvuselela isibindi sakho ukuthi sikhiqize i-glucose entsha evela kwezinye izinto emzimbeni wakho, yize lo mphumela wesibili uthatha isikhathi eside ukuthi uqale. Lesi senzo esiphindwe kabili siqinisekisa ukukhuphuka koshukela wegazi ngokushesha nokuzinzile ezimweni eziphuthumayo.

Kufanele Ngiyithathe Kanjani I-Glucagon Injection?

I-Glucagon injection kufanele inikezwe kuphela uma umuntu enezinkinga ezinzima ze-hypoglycemia futhi engakwazi ukudla noma ukuphuza ngokuphepha. Umuthi ufakwa emsipheni, ngokuvamile ethangeni, engalweni engenhla, noma ezinqeni.

Akudingeki ukhathazeke ngesikhathi sokudla ngemijovo ye-glucagon ngoba isetshenziswa ezimweni eziphuthumayo lapho ukudla kungenzeki. Kodwa-ke, lapho umuntu esebuyela emqondweni futhi ekwazi ukugwinya ngokuphepha, kufanele adle ama-carbohydrate asebenza ngokushesha njengejusi noma amaphilisi e-glucose.

Indawo yokujova kufanele ihlanzeke, kodwa ungalibazisi ukwelashwa ukuze uthole ama-alcohol wipes ngesikhathi esiphuthumayo. Zungezisa izindawo zokujova uma kudingeka imithamo eminingi, yize lokhu akuvamile ukuthi kudingeke. Ngaso sonke isikhathi shayela izinsizakalo eziphuthumayo ngemuva kokunikeza i-glucagon, ngisho noma umuntu ebonakala elulama ngokushesha.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Glucagon Injection?

Umjovo we-Glucagon awuthathwa ngeshejuli ejwayelekile njengemithi yansuku zonke. Kunalokho, umuthi osindisa eziphuthumayo osetshenziswa kuphela uma i-hypoglycemia enkulu yenzeka futhi ukwelashwa kwendabuko kungenzeki.

Umjovo ngamunye unikeza umthamo owodwa wesigameko esisodwa se-hypoglycemic. Abantu abaningi bazobona ushukela wabo wegazi ukhuphuka phakathi kwemizuzu engu-5-15 ngemuva komjovo, nakuba umphumela ogcwele ungase uthathe imizuzu engama-30 ukuthi uthuthuke ngokuphelele.

Kufanele ngaso sonke isikhathi ube ne-glucagon engaphelelwe yisikhathi uma usengozini ye-hypoglycemia enkulu. Shintsha amakhithi aphelelwe yisikhathi ngokuvumelana nosuku lokuphelelwa yisikhathi, ngokuvamile njalo ezinyangeni eziyi-12-24 kuye ngomkhiqizo othile. Umhlinzeki wakho wezempilo uzonquma ukuthi ngabe udinga ukugcina i-glucagon esandleni ngokuya ngokuphathwa kwakho ngakunye kwesifo sikashukela nomlando.

Yiziphi Imiphumela Eceleni Yomjovo we-Glucagon?

Umjovo we-Glucagon ungadala imiphumela eminingana engemihle, kodwa khumbula ukuthi ngesikhathi esiphuthumayo se-hypoglycemic esinzima, izinzuzo zidlula kakhulu lokhu kungakhululeki kwesikhashana. Imiphumela eminingi emibi imnene futhi iyazixazulula yodwa emahoreni ambalwa.

Imiphumela emibi ejwayelekile ongase uyithole ihlanganisa isicanucanu nokuhlanza, okuthinta abantu abaningi abathola imijovo ye-glucagon. Lezi zimpawu zivame ukuqala kungakapheli imizuzu engama-30 yomjovo futhi ngokuvamile ziyancipha kungakapheli amahora ama-2-3.

Nansi imiphumela emibi ongahlangabezana nayo, ehlelwe kusukela kokujwayelekile kuya kokungavamile:

• Isicanucanu nokuhlanza (kujwayelekile kakhulu)
• Ikhanda elibuhlungu nesiyezi
• Ukukhathala nobuthakathaka
• Ubuhlungu besisu noma ukuqaqamba
• Ukuphendula kwendawo yokujova njengobubomvu noma ukuvuvukala
• Ukushaya kwenhliziyo okusheshayo
• Ukujuluka

Lezi zimphendulo ngokuvamile ziyindlela yomzimba wakho yokuphendula ekwenyukeni okusheshayo kukashukela wegazi kanye nokucindezeleka kwesigameko se-hypoglycemic ngokwaso. Abantu abaningi bazizwa ngcono kakhulu lapho ushukela wabo wegazi uzinzile, noma ngabe eminye imiphumela emibi iyaqhubeka.

Imiphumela emibi kodwa ebucayi ingabandakanya ukusabela okukhulu komzimba, nakuba lokhu kungavamile kakhulu. Izimpawu zokusabela okukhulu komzimba zihlanganisa ubunzima bokuphefumula, ukuvuvukala okukhulu, noma ukuqubuka okukhulu. Uma lokhu kwenzeka, funa usizo lwezokwelapha ngokushesha.

Ubani Ongafanele Athole Umjovo We-Glucagon?

Bambalwa kakhulu abantu okufanele bagweme umjovo we-glucagon lapho bebhekene ne-hypoglycemia ebucayi, njengoba umuthi ngokuvamile uphephile kunokuvumela ushukela wegazi ophansi ngokuyingozi ukuthi uqhubeke. Kodwa-ke, zikhona izimo ezithile lapho kudingeka khona ukuqapha okwengeziwe.

Abantu abaziwa ukuthi banezinto ezibazwela ngaphandle kwe-glucagon noma yiziphi izithako emjovweni kufanele bazise abahlinzeki babo bezempilo ngezindlela zokwelapha eziphuthumayo. Ngaphezu kwalokho, labo abanezithombe ezithile ezingavamile ezibizwa ngokuthi ama-pheochromocytomas kufanele basebenzise i-glucagon ngokucophelela okukhulu, njengoba ingase ibangele ukwanda okuyingozi komfutho wegazi.

Abantu abane-insulinomas (izimila ezikhiqiza i-insulin) bangase babe noshukela wegazi ophansi isikhathi eside ngemva kokuba i-glucagon isiphelile, okudinga ukuqapha okwengeziwe kwezokwelapha. Abantu abanezitolo ze-glycogen eziphelile kakhulu, njengalabo abazila ukudla isikhathi eside noma abanobugebengu obungapheli, bangase bangasabeli ngempumelelo ku-glucagon.

Abesifazane abakhulelwe nabancelisayo bangathola ngokuphepha imijovo ye-glucagon ngesikhathi sezimo eziphuthumayo ze-hypoglycemic, njengoba izingozi zoshukela wegazi ophansi kakhulu zidlula noma yiziphi izingozi ezingaba khona zemithi. Njalo xoxa ngomlando wakho wezokwelapha oqondile nomhlinzeki wakho wezempilo lapho uthuthukisa uhlelo lwakho oluphuthumayo lwesifo sikashukela.

Amagama Omkhiqizo Womjovo We-Glucagon

Imikhiqizo eminingana yomjovo we-glucagon iyatholakala, ngamunye unezindlela ezihlukene zokulethwa kanye nezidingo zokulungiselela. Amagama omkhiqizo ajwayelekile afaka i-Baqsimi (i-powder yamakhala), i-Gvoke (ipeni eligcwaliswe ngaphambilini), ne-Zegalogue (i-auto-injector).

I-Baqsimi inikeza inketho ekhethekile yokufutha ngamakhala engadingi ukujova, okwenza kube lula kumalungu omndeni noma abanakekeli abangase bangakhululeki ngezinaliti. I-Gvoke ne-Zegalogue ziza njengamapeni alungele ukusetshenziswa angadingi ukuxutshwa, okwenza kube lula ukusetshenziswa eziphuthumayo.

Amakhithi eziphuthumayo e-glucagon esendabuko afana ne-Glucagon Emergency Kit adinga ukuxuba impushana noketshezi ngaphambi kokujova, nakuba amaningi ala agcinwa ngamanye amasha, anobungane obuningi. Umhlinzeki wakho wezempilo uzokusiza ukuthi ukhethe inketho engcono kakhulu ngokusekelwe endleleni yakho yokuphila, umshwalense, nezintandokazi zakho.

Ezinye izindlela zokujova i-Glucagon

Ngenkathi ukujova i-glucagon kuhlala kuyindinganiso yegolide yokwelapha i-hypoglycemia eqinile, ezinye izindlela zikhona kuye ngesimo nobukhulu be-sugar ephansi yegazi. Nge-hypoglycemia elula kuya kokulingene lapho umuntu eqaphela futhi ekwazi ukugwinya, ama-carbohydrate asebenza ngokushesha ayindlela yokuqala.

Amaphilisi e-glucose, ama-gel, noma uketshezi kusebenza ngokushesha kubantu abaqaphelayo abanokuhlangenwe nezinto eziphansi ze-hypoglycemia. Lezi zinketho zihlanganisa imikhiqizo efana nama-glucose tabs, i-cake frosting, noma i-soda ejwayelekile. Kodwa-ke, lezi zindlela zisebenza kuphela lapho umuntu ekwazi ukuzidla ngokuphepha ngomlomo.

Ezindaweni zasemtholampilo, abahlinzeki bezempilo bangase basebenzise i-dextrose ye-intravenous (isixazululo sikashukela) ukuze bakhulise ngokushesha amazinga e-glucose yegazi. Le ndlela ilusizo ikakhulukazi uma ukufinyelela kwe-IV sekuvele kutholakala noma uma i-glucagon ingase ingasebenzi ngenxa yokuphela kwezitolo ze-glycogen.

Abanye abantu bahlola ama-monitors e-glucose aqhubekayo anezinhlelo zokulethwa kwe-insulin ezizenzakalelayo ukusiza ekuvikeleni iziqephu ezinzima ze-hypoglycemia ngokuphelele. Nakuba lobu buchwepheshe bungathathi indawo ye-glucagon ezimweni eziphuthumayo, bunganciphisa kakhulu imvamisa yezigameko eziphansi ze-sugar yegazi.

Ingabe ukujova i-Glucagon kungcono kune-Oral Glucose?

Umjovo we-Glucagon kanye ne-glucose yomlomo zisebenzela izinhloso ezihlukene ekuphathweni kwesifo sikashukela, okwenza ukuqhathanisa okuqondile kube sengathi kuqhathaniswa isicima-mlilo nesitholi somusi. Ngamunye unendima yawo ekukugcineni uphephile ku-hypoglycemia.

Ukwelashwa nge-glucose yomlomo njengamaphilisi noma ama-gel kusebenza ngokumangalisayo uma uqaphela futhi ukwazi ukugwinya ngokuphepha. Zishesha ukuzisebenzisa, azidingi umjovo, futhi zikhuphula ngempumelelo ushukela wegazi ku-hypoglycemia emnene kuya kwemaphakathi. Abantu abaningi kufanele bazame ukwelashwa ngomlomo kuqala lapho bezwa ushukela wegazi ophansi uza.

Nokho, umjovo we-glucagon awunakushintshwa uma umuntu engazi lutho, enezithuthwane, noma engakwazi ukugwinya ngokuphepha. Kulezi zimo ezinzima, i-glucose yomlomo ingaba yingozi njengoba ingase ibangele ukuminyanisa noma ukungenisa emaphashini.

Cabanga nge-glucose yomlomo njengomugqa wakho wokuqala wokuzivikela ezigamekweni zikashukela wegazi ophansi ongawulawula, kuyilapho umjovo we-glucagon usebenza njengokusekelwa kwakho okuphuthumayo ezimweni ezisongela impilo. Ukuba nazo zombili izinketho ezitholakalayo kukunikeza ukuvikelwa okuphelele emazingeni ahlukene e-hypoglycemia.

Imibuzo Evame Ukubuzwa Mayelana Nomjovo we-Glucagon

Ingabe umjovo we-Glucagon uphephile ezigulini zenhliziyo?

Umjovo we-Glucagon ngokuvamile uphephile kubantu abanezifo zenhliziyo, ikakhulukazi uma kubhekwa izingozi ezingathi sína ze-hypoglycemia engelashwanga. Umuthi ungase ukwandise okwesikhashana izinga lokushaya kwenhliziyo nomfutho wegazi, kodwa lezi zinto zivame ukuba mnene futhi zihlala isikhashana.

Ukucindezeleka kwenhliziyo nemithambo yegazi okuvela ku-hypoglycemia eqinile ngokwayo kubeka ingozi enkulu enhliziyweni yakho kunomjovo we-glucagon osetshenziselwa ukuyelapha. Ushukela wegazi ophansi ungenza izinkinga eziyingozi zokushaya kwenhliziyo, ngakho ukwelashwa ngokushesha nge-glucagon ngokuvamile kuyindlela ephephe kakhulu.

Uma unesifo senhliziyo esikhulu, xoxa ngesimo sakho esithile nodokotela wakho wenhliziyo kanye nodokotela we-endocrinologist. Bangakwazi ukusiza ekwakheni uhlelo oluphuthumayo olucabangela kokubili izidingo zakho zokuphatha isifo sikashukela kanye nempilo yenhliziyo nemithambo yegazi.

Kufanele ngenzeni uma ngisebenzisa i-Glucagon eningi ngengozi?

Ukweqisa kwe-glucagon ngengozi akuvamile ngoba imikhiqizo eminingi iqukethe amanani omthamo owodwa, kodwa uma kwenzeka, qapha imiphumela engemihle eyengeziwe efana nesicanucanu esibi, ukuhlanza, noma amazinga kashukela egazi aphezulu kakhulu. Xhumana nomhlinzeki wakho wezempilo noma izinsiza eziphuthumayo ukuze uthole isiqondiso.

Okukhathaza kakhulu nge-glucagon eningi ukuthi ingase ikhuphule ushukela wegazi phezulu kakhulu, okungenzeka kubangele izimpawu ezinjengokoma ngokweqile, ukuvama ukuchama, noma ukukhiqizwa kwama-ketone. Hlola amazinga e-glucose yegazi njalo futhi ulandele imiyalelo yomhlinzeki wakho wezempilo yokuphatha ushukela wegazi ophezulu.

Izimo eziningi zokweqisa kwe-glucagon zizixazulula zodwa njengoba umuthi uqhutshwa ngumzimba wakho, ngokuvamile kungakapheli amahora ambalwa. Kodwa-ke, ukuhlolwa kwezokwelapha okuchwepheshile kuhlakaniphile ngaso sonke isikhathi ukuqinisekisa ukuqapha okufanele nokwelashwa uma kudingeka.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Glucagon?

Lo mbuzo awusebenzi kahle emjovweni we-glucagon ngoba akuwona umuthi ohleliwe njengemithi yesifo sikashukela yansuku zonke. I-Glucagon isetshenziswa kuphela ezimweni eziphuthumayo lapho i-hypoglycemia enzima yenzeka futhi ezinye izindlela zokwelapha zingenzeki.

Esikhundleni sokukhathazeka ngemithamo ephuthelwe, gxila ekuqinisekiseni ukuthi ngaso sonke isikhathi unayo i-glucagon engaphelelwe yisikhathi uma uyidinga. Hlola izinsuku zokuphelelwa yisikhathi njalo futhi ushintshe amakhithi aphelelwe yisikhathi ngokwezincomo zomnikezeli wakho wezempilo.

Uma uhlangabezana ne-hypoglycemia enzima futhi ungenayo i-glucagon etholakalayo, shayela izinsiza eziphuthumayo ngokushesha. Odokotela bezimo eziphuthumayo baphethe i-glucagon futhi bangahlinzeka ngelashwa olidingayo ngenkathi bekuthutha ukuze uthole ukunakekelwa kwezokwelapha.

Ngingayeka nini ukuthwala i-Glucagon?

Isinqumo sokuyeka ukuthwala i-glucagon kufanele senziwe ngaso sonke isikhathi ngokubonisana nomhlinzeki wakho wezempilo, ngokusekelwe ekuphathweni kwakho kukashukela ngamunye kanye nezici eziyingozi ze-hypoglycemia. Ngokuvamile, uzodinga i-glucagon uma nje usengozini ye-hypoglycemia enzima.

Abantu abanesifo sikashukela sohlobo 1 ngokuvamile badinga ukufinyelela i-glucagon impilo yabo yonke, njengoba behlala bengozini ethile yezigameko zikashukela ophansi. Labo abanesifo sikashukela sohlobo 2 abasebenzisa i-insulin bangase futhi badinge ukufinyelela i-glucagon yesikhathi eside, kuye ngohlelo lwabo lokwelashwa nomlando we-hypoglycemia.

Umhlinzeki wakho wezempilo uzocabangela izici ezinjengokulawulwa kukashukela egazini lakho, izinguquko zemithi, izici zokuphila, nomlando wezigameko ze-hypoglycemic lapho kuxoxwa ngokuthi usadinga yini i-glucagon ephuthumayo etholakalayo.

Ingabe Amalungu Omndeni Anganginika Umjovo We-Glucagon?

Yebo, amalungu omndeni, abangane, noma abanakekeli bangafundiswa futhi kufanele baqeqeshwe ukuthi banikeze imijovo ye-glucagon ezimeni eziphuthumayo. Eqinisweni, ukuba nabanye abazi ukuthi bangayisebenzisa kanjani i-glucagon yakho kubalulekile, ngoba ungase ungazi lutho noma ungenakuziphatha ngesikhathi se-hypoglycemia enzima.

Imikhiqizo eminingi ye-glucagon iza nemiyalelo elula futhi yakhelwe ukusetshenziswa ngabantu abangewona odokotela. Cabangela ukuthi umhlinzeki wakho wezempilo abonise indlela yokujova kumalungu omndeni wakho noma abangane abaseduze abangase babe khona esimweni esiphuthumayo.

Zijwayeze izimo ngenethiwekhi yakho yokusekela, ukuze wonke umuntu azizwe enethemba mayelana nokubona izimpawu ze-hypoglycemia enzima nokuphatha i-glucagon ngendlela efanele. Khumbula ukugcizelela ukuthi kufanele ngaso sonke isikhathi babize izinsiza eziphuthumayo ngemva kokunikeza i-glucagon, ngisho noma ubonakala ululama ngokushesha.