Iyini i-Gold Compound: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

Ama-gold compounds yimithi ekhethekile equkethe igolide langempela elisetshenziswa odokotela ukwelapha i-rheumatoid arthritis eqinile lapho ezinye izindlela zokwelapha zingasebenzi kahle ngokwanele. Le mithi isebenza ngokuthulisa amasosha akho omzimba ukunciphisa ukuvuvukala kwamalunga nobuhlungu. Ngenkathi bengabhaliwe njalo namuhla ngenxa yezinye izindlela ezintsha, ama-gold compounds angasebenza kahle kakhulu ezigulini ezithile ezidinga izinketho zokwelapha eziqinile.

Iyini i-Gold Compound?

Ama-gold compounds yimithi kadokotela equkethe usawoti wegolide, okuyizinhlobo zegolide ezilungiselelwe ngokukhethekile ukusetshenziswa kwezokwelapha. Izinhlobo ezivame kakhulu zihlanganisa i-gold sodium thiomalate (enikezwa ngomjovo) kanye ne-auranofin (ethathwa ngomlomo). Lokhu akufani negolide lobucwebe - zishintshwe ngamakhemikhali ukusebenza njengemithi emzimbeni wakho.

Udokotela wakho angase acabangele ama-gold compounds uma une-rheumatoid arthritis eqinile engaphendulanga kahle kwezinye izindlela zokwelapha. Ayingxenye yeqembu elibizwa ngokuthi imithi elungisa izifo ze-antirheumatic (DMARDs), okusho ukuthi ayiphathi nje izimpawu kodwa empeleni yehlisa ukulimala kwamalunga ngokuhamba kwesikhathi.

Isetshenziselwani i-Gold Compound?

Ama-gold compounds asetshenziselwa ikakhulukazi ukwelapha i-rheumatoid arthritis, isimo lapho amasosha akho omzimba ehlasela amalunga akho ngempela. Zisiza kakhulu lapho i-arthritis yakho isebenza futhi ibangela ubuhlungu obukhulu, ukuvuvukala, nokulimala kwamalunga ukuthi eminye imithi ayilawulanga ngempumelelo.

Le mithi isebenza kahle kubantu abaye baba ne-rheumatoid arthritis izinyanga eziningana noma iminyaka futhi badinga ukwelashwa okuqinile. Udokotela wakho angase futhi acabangele uma uke waba nemiphumela emibi evela kweminye imithi ye-arthritis noma uma ukwelashwa kwakho kwamanje kungavimbeli ukulimala kwamalunga.

Ezimweni ezingavamile, odokotela bangase banikeze imithi yegolide kwezinye izifo ezizihlaselayo njenge-psoriatic arthritis, kodwa lokhu akuvamile. Isinqumo sokusebenzisa ukwelashwa ngegolide sidinga ukucatshangelwa ngokucophelela kwesimo sakho esithile kanye nomlando wakho wezokwelapha.

Isebenza Kanjani I-Gold Compound?

I-Gold compounds isebenza ngokucindezela amasosha akho omzimba asebenza ngokweqile, okuyilokho okubangela ukuvuvukala ku-rheumatoid arthritis. Cabanga ngamasosha akho omzimba edidekile futhi ehlasela amalunga akho - igolide lisiza ukuthulisa lokhu kudideka.

Le mithi ithathwa njengeqinile ngokulinganisela uma iqhathaniswa nezinye izindlela zokwelapha i-arthritis. Ziqine kunezidakamizwa ezingavuvukali eziyisisekelo kodwa azinamandla njengamanye ama-biologics amasha. Igolide lakheka kancane emzimbeni wakho ngokuhamba kwesikhathi, yingakho kungathatha izinyanga eziningana ukuzwa izinzuzo eziphelele.

Indlela eqondile igolide elisebenza ngayo ayiqondakali ngokuphelele, kodwa kubonakala sengathi inciphisa ukusebenza kwamanye amaseli omzimba abangela ukuvuvukala kwamalunga. Lokhu kusiza ukunciphisa ubuhlungu, ukuvuvukala, futhi kuvimbela ukulimala kwamalunga okuqhubekayo ngokuhamba kwesikhathi.

Kufanele Ngiyithathe Kanjani I-Gold Compound?

Indlela othatha ngayo i-gold compound incike ohlotsheni oluthile udokotela wakho alubhala. Igolide elijovwayo (gold sodium thiomalate) linikezwa njengesibhamu emsipheni wakho, ngokuvamile ezinqeni zakho noma ethangeni, ngumhlinzeki wezempilo ehhovisi lezokwelapha.

Ngegolide elijovwayo, ngokuvamile uzoqala ngemijovo yamasonto onke ezinyangeni ezimbalwa zokuqala, bese ushintshela emijovweni yanyanga zonke uma ukwelashwa kusebenza kahle. Uzodinga ukuhlala emtholampilo cishe imizuzu engama-30 ngemuva komjovo ngamunye ukuze ubheke noma yiziphi izindlela zokuphendula ngokushesha.

Uma ubhalelwe igolide lomlomo (auranofin), uzolithatha ngomlomo nokudla ukuze unciphise isisu esibuhlungu. Ukulithatha nobisi noma ukudla okugcwele kungasiza ekuvikeleni isicanucanu. Udokotela wakho ngokuvamile uzoqala ngomthamo ophansi bese ewukhulisa kancane kancane ngokuya ngendlela ozosabela ngayo.

Ungaqomi ukuya emihlanganweni noma imithamo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuhlolwa kwegazi njalo kubalulekile ngenkathi uthatha izinhlanganisela zegolide ukuqapha imiphumela emibi futhi uqinisekise ukuthi imithi isebenza ngokuphepha.

Kufanele Ngiyithathe Isikhathi Esingakanani Inhlanganisela Yegolide?

Ukwelashwa ngezinhlanganisela zegolide ngokuvamile kuyisibopho sesikhathi eside esingathatha iminyaka eminingi uma sikusebenzela kahle. Abantu abaningi badinga ukuyithatha okungenani izinyanga ezi-3-6 ngaphambi kokuba bathole ukuthuthuka okukhulu ezimpawini zabo ze-arthritis.

Udokotela wakho uzohlola ukuthi imithi isebenza kahle kangakanani njalo emva kwezinyanga ezimbalwa. Uma uphendula kahle futhi ungenayo imiphumela emibi, ungaqhubeka nokwelashwa iminyaka eminingi. Abanye abantu bathatha izinhlanganisela zegolide iminyaka engu-5 noma ngaphezulu uma beqhubeka nokuzuza.

Isinqumo sokuyeka ukwelashwa ngegolide sincike ezintweni eziningana ezihlanganisa ukuthi ilawula kahle kangakanani i-arthritis yakho, ukuthi ngabe uhlangabezana nemiphumela emibi, nokuthi ngabe ezinye izindlela zokwelapha ezintsha zingase zikusebenzele kangcono. Udokotela wakho uzosebenza nawe ukuthola umugqa wesikhathi ongcono kakhulu wesimo sakho esithile.

Yini Imiphumela Emibi Yezinhlanganisela Zegolide?

Izinhlanganisela zegolide zingabangela imiphumela emibi ehlukahlukene, kusukela kokulula kuya kokukhulu, yingakho ukuqapha njalo kubaluleke kangaka. Abantu abaningi bathola eminye imiphumela emibi, kodwa eminingi iyalawuleka ngokunakekelwa kwezempilo okufanele.

Nawa amanye amiphumela emibi evame kakhulu ongase uyithole:

• Ukuqubuka kwesikhumba noma ukuluma
• Izilonda zomlomo noma ukunambitheka kwensimbi
• Ukuqunjelwa noma isisu esicasukile
• Ukukhathala noma ubuthakathaka
• Ukuqina kwezinwele

Le miphumela emibi ejwayelekile ivame ukuba mnene futhi ingathuthuka njengoba umzimba wakho ujwayela imithi.

Imiphumela emibi engathi sína idinga ukunakekelwa kwezempilo ngokushesha futhi ihlanganisa:

• Ukusabela okukhulu kwesikhumba noma ukuqubuka okubanzi
• Izinkinga zezinso (ukushintsha ekuchameni)
• Izifo zegazi (ukuphuka noma ukuphuma kwegazi okungavamile)
• Izilonda ezinzima zomlomo
• Izinkinga zamaphaphu (ukukhwehlela okuqhubekayo noma ukuphefumula kanzima)

Izinkinga ezingavamile kodwa ezinzima zingabandakanya ukusabela okukhulu komzimba, ukulimala kwesibindi, noma ukwehla okukhulu kwamaseli egazi. Yingakho udokotela wakho ezokuqapha eduze ngezivivinyo zegazi ezivamile nokuhlolwa njalo ngesikhathi sokwelashwa kwakho.

Ubani Ongafanele Athathe I-Gold Compound?

Abanye abantu kufanele bagweme ama-gold compounds ngenxa yengozi eyengeziwe yezinkinga ezinzima. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi.

Akufanele uthathe ama-gold compounds uma une:

• Isifo sezinso esinzima
• Izinkinga ezinkulu zesibindi
• Izifo zegazi noma ukwehla kwamaseli egazi
• Ukusabela okukhulu komzimba ngaphambilini ku-gold
• Isifo samathumbu esivuvukalayo (se-gold yomlomo)

Udokotela wakho uzophinda aqaphele kakhulu mayelana nokuyalela ama-gold compounds uma ukhulelwe, uncelisa, noma uhlela ukukhulelwa, njengoba le mithi ingamthinta umntwana wakho.

Abantu abanesifo sikashukela, umfutho wegazi ophezulu, noma ezinye izimo ezingamahlalakhona bangase bakwazi ukuthatha ama-gold compounds, kodwa bazodinga ukuqapha okwengeziwe. Hlala utshela udokotela wakho ngazo zonke izimo zakho zezokwelapha nemithi ngaphambi kokuqala ukwelashwa.

Amagama Omkhiqizo we-Gold Compound

Ama-gold compounds atholakala ngaphansi kwamagama amaningi omkhiqizo, kuye ngohlobo oluthile nomkhiqizi. Ifomu elijovwayo (i-gold sodium thiomalate) livame ukwaziwa njenge-Myochrysine, kuyilapho i-gold yomlomo (auranofin) ithengiswa njenge-Ridaura.

Ezinye izinhlobo ezivamile zingase zitholakale, kodwa ama-gold compounds ngokuvamile abiza kakhulu kuneziningi zeminye imithi ye-arthritis. Ukumbozwa kwakho komshuwalense nezinzuzo zekhemisi kuzonquma ukuthi iyiphi inguqulo ethile yomkhiqizo noma ejwayelekile oyitholayo.

Njalo sebenzisa uhlobo oluqondile kanye nokwakheka okubekwe ngudokotela wakho, njengoba amalungiselelo ahlukene angase abe nemiphumela ehlukile kancane noma izidingo zokulinganisa.

Ezinye Izindlela Zokwelapha Ngegolide

Imithi eminingi emisha manje iyatholakala engase isebenze kangcono noma ibe nemiphumela emibi embalwa kunemithi yegolide. Lezi ezinye izindlela zihlanganisa i-methotrexate, evame ukuba yindlela yokuqala yokwelapha i-DMARD ye-rheumatoid arthritis.

Imithi ye-Biologic efana ne-adalimumab (Humira), i-etanercept (Enbrel), kanye ne-infliximab (Remicade) iyizinketho ezintsha eziqondise izingxenye ezithile zomzimba. Le mithi ivame ukusebenza kangcono kunemithi yegolide kodwa futhi ibiza kakhulu.

Ezinye izindlela zokwelapha ze-DMARD ezivamile njenge-sulfasalazine, i-hydroxychloroquine, kanye ne-leflunomide nazo zingaba izinketho kuye ngesimo sakho esithile. Udokotela wakho uzocabangela izinto ezinjengobunzima besifo sakho, ezinye izimo zezokwelapha, kanye nomshwalense lapho ekhetha ukwelashwa okungcono kakhulu kuwe.

Abantu abaningi namuhla baqala nge-methotrexate noma ama-biologics ngaphambi kokucabangela imithi yegolide, kodwa ukwelashwa ngegolide kungase kusabalulekile ezigulini ezithile ezingasabeli kahle kwezinye izindlela zokwelapha.

Ingabe Imithi Yegolide Ingcono Kune-Methotrexate?

Imithi yegolide kanye ne-methotrexate yomibili iyindlela yokwelapha ephumelelayo ye-rheumatoid arthritis, kodwa i-methotrexate ngokuvamile ithathwa njengendlela yokwelapha yokuqala ekhethwayo namuhla. I-Methotrexate ivame ukusebenza ngokushesha, inemiphumela emibi elindelekile, futhi kulula ukuyiqapha nokuyilungisa.

Imithi yegolide ingase isebenze kangcono kwabanye abantu, ikakhulukazi labo abangasabelanga kahle ku-methotrexate noma ezinye izindlela zokwelapha ze-DMARD. Kodwa-ke, ukwelashwa ngegolide kudinga ukuqapha okuvame kakhulu futhi kunengozi enkulu yemiphumela emibi engathi sína.

Ukukhetha phakathi kwala mithi kuncike esimweni sakho, okuhlanganisa ukuthi i-arthritis yakho inobukhulu obungakanani, yiziphi ezinye izindlela zokwelapha ozizame, kanye nezinto eziyingozi kuwe. Udokotela wakho uzokusiza ukuthi ulinganise izinzuzo nezingozi zokukhetha ngakunye.

Abantu abaningi namuhla basebenzisa i-methotrexate njengendlela yabo yokwelapha eyinhloko, ngezinye izikhathi ihlanganiswe neminye imithi, kuyilapho izinhlanganisela zegolide zivame ukugcinelwa amacala lapho ezinye izindlela zokwelapha zingasebenzi kahle.

Imibuzo Evame Ukubuzwa Mayelana Nenhlangano Yegolide

Ingabe Inhlangano Yegolide Iphephile Kubantu Abanezifo Zenhliziyo?

Izinhlanganisela zegolide ngokuvamile zingasetshenziswa ngokuphepha kubantu abanezifo zenhliziyo, kodwa kudingeka ukuqapha okwengeziwe. Udokotela wakho uzofuna ukukuqapha eduze ngoba eminye imiphumela emibi yokwelashwa ngegolide, njengokugcinwa kwamanzi noma izinkinga zezinso, kungase kuthinte isimo senhliziyo yakho.

Uma unesifo senhliziyo, qiniseka ukuthi udokotela wakho wenhliziyo kanye nodokotela wamathambo bayaxhumana mayelana nohlelo lwakho lokwelapha. Kungase kudingeke ukuthi balungise imithi yakho yenhliziyo noma bakuqaphe kaningi ngenkathi usebenzisa ukwelashwa ngegolide.

Ngingenzani Uma Ngiphuzile Inhlangano Yegolide Engakanani?

Uma ngengozi uthatha inani eliningi lenhlangano yegolide yomlomo, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ungalindi ukubona ukuthi uzizwa ugula - ukwelashwa ngokushesha kubalulekile ukuvimbela izinkinga ezinzima.

Ngegolide elijovwayo, ukweqisa akunakwenzeka njengoba umhlinzeki wezempilo ekunika imijovo. Kodwa-ke, uma uzizwa ungajwayelekile ngemva komjovo, xhumana nodokotela wakho ngokushesha. Izimpawu zegolide eliningi ohlelweni lwakho zingabandakanya isicanucanu esibi, ukuhlanza, noma ukusabela kwesikhumba.

Ngingenzani Uma Ngedlule Umthamo Wenhlanganisela Yegolide?

Uma uphuthelwa umthamo wenhlangano yegolide yomlomo, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ngemithi yegolide ejovwayo, xhumana nehhovisi likadokotela wakho ukuze uhlele kabusha i-aphoyintimenti yakho ngokushesha ngangokunokwenzeka. Ukweqa imijovo kunganciphisa ukusebenza kokwelashwa kwakho, ngakho kubalulekile ukuthi uhlale esimisweni.

Ngingayeka nini Ukuthatha I-Gold Compound?

Ungalokothi uyeke ukuthatha i-gold compound ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Udokotela wakho uzokusiza ukuthi unqume isikhathi esifanele sokuyeka ngokusekelwe ekutheni i-arthritis yakho ilawulwa kahle kangakanani nokuthi ngabe uhlangabezana nemiphumela emibi.

Uma udinga ukuyeka ukwelashwa ngegolide, udokotela wakho cishe uzokwenza ukuthi unciphise kancane kancane umthamo noma imvamisa kunokuyeka kungazelelwe. Bazophinde baxoxe ngezindlela zokwelapha ezingezinye ukuze baqinisekise ukuthi i-arthritis yakho ihlala ilawulwa kahle.

Ngingakwazi yini Ukuphuza Utshwala Ngenkathi Ngithatha I-Gold Compound?

Ngokuvamile kungcono ukukhawulela ukusetshenziswa kotshwala ngenkathi uthatha ama-gold compounds, njengoba kokubili kungase kuthinte isibindi nezinso zakho. Ukuphuza utshwala ngokulinganisela kungase kulungele abanye abantu, kodwa kufanele uxoxe ngalokhu nodokotela wakho.

Uma uphuza utshwala, udokotela wakho angase afune ukuqapha ukusebenza kwesibindi sakho ngokucophelela ngemivivinyo yegazi eyengeziwe. Njalo yiba qotho nomhlinzeki wakho wezempilo mayelana nokusetshenziswa kotshwala ukuze bakwazi ukukunikeza isiqondiso esingcono kakhulu sesimo sakho.