Yini i-Griseofulvin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Griseofulvin iyikhambi elilwa nesikhunta elilwa nezifo zokukhunta esikhumbeni sakho, izinwele, nezinzipho. Sekuyiminyaka eminingi kuyindlela yokwelapha ethembekile, isiza abantu ukunqoba izifo zokukhunta ezinzima ezithinta izingxenye zomzimba wakho ezenziwe nge-keratin (iprotein ezinweleni zakho, esikhumbeni sakho, nezinzipho).

Lo muthi usebenza ngendlela ehlukile kunezinye izindlela zokwelapha isikhunta ngoba ufakwa ku-keratin entsha njengoba ikhula. Cabanga ngakho njengokwakha isivikelo ngqo ezivikelweni zomzimba wakho zemvelo ezimelana nesikhunta.

Yini i-Griseofulvin?

I-Griseofulvin iyikhambi elilwa nesikhunta elithathwa ngomlomo elivela ohlotsheni lwesikhunta olubizwa nge-Penicillium. Yenzelwe ngqo ukwelapha izifo zokukhunta ezithinta isikhumba sakho, izinwele, nezinzipho - izimo lapho okugcotshwayo okuqondile ngokuvamile kungafinyeleli ngempumelelo.

Umuthi uyatholakala ngamaphilisi nangoketshezi, okwenza ukuthi utholakale kubantu abadala kanye nezingane. Kuthathwa njengokwelashwa kwesistimu, okusho ukuthi kusebenza kuwo wonke umzimba wakho kunokuba nje ngaphezulu lapho uwusebenzisa khona.

Ngokungafani nemithi emisha elwa nesikhunta, i-griseofulvin inendlela eyingqayizivele yokusebenza eyenza isebenze ikakhulukazi ezinhlotsheni ezithile zezifo zokukhunta ezinzima. Sekusiza abantu iminyaka engaphezu kwengama-60, inika odokotela neziguli ukuzethemba emlandweni wayo.

Isetshenziselwani i-Griseofulvin?

I-Griseofulvin iphatha izifo zokukhunta zesikhumba, izinwele, nezinzipho ezingasabeli kahle ekwelashweni okungaphezulu. Udokotela wakho ngokuvamile uzokunika umuthi uma okugcotshwayo nama-oyinti bengasebenzi noma uma ukutheleleka kumboza indawo enkulu.

Umuthi ulusizo ikakhulukazi ezimweni eziningana ezithile ezingaba nzima kakhulu futhi zikhathaza ukubhekana nazo:

• Isifo sesikhumba sekhanda (tinea capitis) - ikakhulukazi esivamile ezinganeni
• Isifo sesikhumba somzimba (tinea corporis) uma sisabalele
• Unyawo lomgijimi (tinea pedis) olunzima noma oluphindaphindayo
• Ukulunywa kwesitho sangasese (tinea cruris) okungaphendulanga emithini esetshenziswa ngaphandle
• Izifo zezipikili zamafungi (onychomycosis) ezipikilini zezandla nezinzwane
• Izifo zendawo yentshebe nezinyebe (tinea barbae)

Lezi zifo zingaba nenkani ngoba zihlala zijule ezakhiweni ze-keratin zomzimba wakho. I-Griseofulvin ifinyelela lezi zindawo ngempumelelo, okuyenza ibe yindlela yokwelapha ebalulekile lapho ezinye izindlela zehluleka.

Isebenza Kanjani I-Griseofulvin?

I-Griseofulvin isebenza ngokuphazamisa ikhono leseli le-fungal lokuhlukanisa nokuphindaphinda. Ingxenyana yayo ifakwa ku-keratin yesikhumba sakho, izinwele, nezipikili njengoba amaseli amasha ekhula, idala indawo lapho ama-fungi engakwazi ukusinda khona.

Umuthi ubhekwa njengomuthi oqinile phakathi kokwelashwa kwama-antifungal. Awunamandla njengeminye imithi emisha, kodwa usebenza kahle kakhulu ezinhlotsheni ezithile zezifo ezihlaselayo. Lokhu kuyenza ibe yindlela ethembekile elinganisa ukusebenza kahle kanye nephrofayili yokuphepha eqondakala kahle.

Okuthakazelisayo nge-griseofulvin ukuthi ayibulali nje ama-fungi akhona - ivimbela izifo ezintsha ukuthi zingathathi indawo. Njengoba umzimba wakho ngokwemvelo ushintsha isikhumba esidala, izinwele, namaseli ezipikili, ukukhula okusha kuqukethe i-griseofulvin, okwenza kungamelani nokuhlasela kwama-fungi.

Le nqubo ithatha isikhathi ngoba udinga ukulinda i-keratin enesifo ukuthi ikhule iphinde ithathelwe indawo yizicubu ezinempilo, ezivikelekile. Yingakho izifundo zokwelapha zivame ukuba amasonto amaningana kuya ezinyangeni.

Kufanele Ngiyithathe Kanjani I-Griseofulvin?

Thatha i-griseofulvin ngendlela eqondile njengoba udokotela wakho ekunqumele ngayo, ngokuvamile kanye noma kabili ngosuku ngokudla. Ukuyithatha ngokudla, ikakhulukazi okunezinye izinto ezinamafutha, kusiza umzimba wakho ukuthi umunce umuthi ngempumelelo.

Ukuze kumuncwe kahle, cabanga ukuthatha imithi yakho nokudla okufana nobisi, u-ayisikhilimu, noma ukudla okunamalungiselelo amafutha anempilo. Lokhu kungathuthukisa kakhulu ukuthi umzimba wakho uyisebenzisa kanjani imithi. Gwema ukuyithatha esiswini esingenalutho, ngoba lokhu kunganciphisa ukusebenza kwayo.

Uma uthatha uhlobo oluyisiqaba, nyakazisa ibhodlela kahle ngaphambi kwesilinganiso ngasinye. Sebenzisa idivayisi yokulinganisa ehambisana nemithi yakho kunokuba usebenzise izipuni zasendlini ukuze uqinisekise ukulinganisa okunembile.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Uma unikezwe imithamo kabili ngosuku, yihlukanise ngamahora angaba ngu-12. Ukusetha izikhumbuzi zocingo kungakusiza ukuthi uhlale emgqeni ngohlelo lwakho lokwelashwa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Griseofulvin?

Ubude bokwelashwa buhlukahluka kakhulu ngokuya ngohlobo nendawo yokutheleleka kwakho. Ukutheleleka kwesikhumba ngokuvamile kudinga amasonto angu-2-4 okwelashwa, kuyilapho ukutheleleka kwezinzipho kungase kudingeke izinyanga ezingu-4-6 noma ngaphezulu.

Isifo sembaza ekhanda ngokuvamile sidinga amasonto angu-6-8 okwelashwa, futhi udokotela wakho uzofuna ukukubona njalo ukuze aqaphe ukuqhubeka. Ukutheleleka kwezinzipho ngokuvamile kuthatha izinyanga ezingu-4-6 ukuthi kuqede, kuyilapho ukutheleleka kwezinzipho zozwane ngokuvamile kudinga izinyanga ezingu-6-12 ngoba izinzipho zikhula kancane.

Udokotela wakho uzoqoka ubude obuqondile ngokuya ngokutheleleka kwakho okuthile nokuthi usabela kanjani ekwelashweni. Bangase bathathe amasampula noma benze izivivinyo ukuze baqinisekise ukuthi ukutheleleka kuqedwe ngokuphelele ngaphambi kokuyeka imithi.

Kubalulekile ukuqeda inkambo ephelele ngisho noma uzizwa ungcono noma ukutheleleka kubonakala sengathi kuqediwe. Ukuyeka ngaphambi kwesikhathi kungavumela ukutheleleka ukuthi kubuye, okungenzeka ukuthi kwenze kube nzima ukukwelapha okwesibili.

Yiziphi Imiphumela Eceleni Ye-Griseofulvin?

Abantu abaningi bayayibekezelela i-griseofulvin kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathi sína ayivamile, futhi abantu abaningi bathola imiphumela emincane kuphela uma ikhona.

Imiphumela evamile ongase uhlangabezane nayo ihlanganisa:

• Ikhanda elibuhlungu - ngokuvamile elingelibi futhi lesikhashana
• Ukucanuzela kwenhliziyo noma isisu esibuhlungu
• Ukuphuma isifo sohudo noma izitulo ezithambile
• Isiyezi noma ukuzizwa unovalo
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Ukuqubuka kwesikhumba noma ukwanda kokuzwela elangeni

Le miphumela ivamise ukulawuleka futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Ukuthatha umuthi nokudla kungasiza ukunciphisa imiphumela emibi ehlobene nesisu.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha:

• Ukuphendula kwesikhumba okukhulu noma ukuqubuka okusabalalele
• Ukuphalaza okuqhubekayo noma ubuhlungu obukhulu besisu
• Ukulimala okungajwayelekile noma ukuphuma igazi
• Ukuphuzi kwesikhumba noma amehlo (i-jaundice)
• Ikhanda elibuhlungu elinamandla elinoshintsho embonweni
• Izimpawu ze-lupus-like syndrome (ubuhlungu bamalunga, ukuqubuka kwesihlahla ebusweni)

Imiphumela emibi engavamile kakhulu kodwa ebucayi ihlanganisa izinkinga zesibindi nezifo zegazi. Udokotela wakho angase ayalele ukuhlolwa kwegazi ngezikhathi ezithile ngesikhathi sokwelashwa kwesikhathi eside ukuze aqaphele lezi zinkinga.

Ubani Ongafanele Athole i-Griseofulvin?

I-Griseofulvin ayifanele wonke umuntu, futhi udokotela wakho uzocabangela ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo nezimo ezithile zenza lo muthi ungafaneleki noma uyingozi.

Akufanele uthathe i-griseofulvin uma une:

• Isifo sesibindi esibi noma umlando wezinkinga zesibindi
• I-Lupus noma izimo ezinjenge-lupus
• I-Porphyria (isifo segazi esingavamile)
• Ukungezwani okwaziwayo ne-griseofulvin noma yiziphi izithako zayo

Ukuqapha okukhethekile kuyadingeka uma ukhulelwe noma uhlela ukukhulelwa. I-Griseofulvin ingabangela ukukhubazeka kokuzalwa futhi kufanele igwenywe ngesikhathi sokukhulelwa. Bobabili abesilisa nabesifazane kufanele basebenzise izindlela zokuvimbela inzalo ezithembekile ngesikhathi sokwelashwa kanye nenyanga eyodwa ngemva kokuyeka umuthi.

Udaktela wakho uzophinda aqaphele mayelana nokunikeza i-griseofulvin uma unezinkinga zezinso, usebenzisa ama-blood thinners, noma unomlando wezifo zegazi. Lezi zimo akudingeki zikuvimbele ukuthatha imithi, kodwa zidinga ukuqashwa okuseduze.

Amagama Omkhiqizo we-Griseofulvin

I-Griseofulvin itholakala ngaphansi kwamagama amaningi omkhiqizo, nakuba ivame ukunikezwa njengomuthi ojwayelekile. Amagama omkhiqizo aziwa kakhulu afaka i-Grifulvin V ne-Gris-PEG.

I-Grifulvin V iyindlela yendabuko ebilokhu itholakala iminyaka eminingi. I-Gris-PEG iyindlela entsha eyenzelwe ukuba ingene kangcono emzimbeni wakho, okungenzeka ivumele imithamo ephansi ngenkathi igcina ukusebenza.

Umthwebuli wakho wemithi angase athathele indawo i-griseofulvin ejwayelekile ngezinhlobo zomkhiqizo ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo. Izinhlobo ezijwayelekile zisebenza kahle futhi zivame ukuthengeka, okwenza ukwelashwa kufinyeleleke kalula.

Ezinye Izindlela ze-Griseofulvin

Eminye imithi eminingi elwa nesikhunta ingelapha izifo ezifanayo, nakuba ukukhetha okungcono kuncike esimweni sakho esithile kanye nezimo. Udokotela wakho angase acabange ezinye izindlela uma i-griseofulvin ingakulungele noma uma ukutheleleka kwakho kungasabeli ekwelashweni.

Ezinye izindlela ezivamile zifaka i-terbinafine (Lamisil), evame ukukhethwa ngezifo zezipikili ngoba ngokuvamile isebenza ngokushesha. I-Itraconazole (Sporanox) enye inketho esebenza kahle ezifweni ezihlukahlukene zesikhunta kodwa ingase ibe nokuxhumana okuningi kwemithi.

Ezifweni ezithile zesikhumba, ama-antifungals asekhanda afana ne-clotrimazole, miconazole, noma ukhilimu we-terbinafine angase aneza. Lokhu kugwema imiphumela engemihle engaba khona yemithi yomlomo kodwa kungenzeka ingasebenzi ezifweni ezisabalale noma ezijulile.

Imithi emisha elwa nesikhunta efana ne-fluconazole ingase icatshangelwe ezifweni ezithile, nakuba ngokuvamile zingezona izindlela zokwelapha zokuqala zezimo i-griseofulvin eziphatha kahle kakhulu.

Ingabe i-Griseofulvin ingcono kune-Terbinafine?

I-Griseofulvin ne-terbinafine yomibili imithi elwa nesikhunta esisebenzayo, kodwa inamandla ahlukene futhi ilungele izimo ezihlukene. Ukukhetha phakathi kwazo kuncike ekuthelelekeni kwakho okuthile, umlando wezokwelapha, nezinye izinto.

I-Terbinafine ivame ukukhethwa ngezifo zezipikili ngoba ngokuvamile isebenza ngokushesha futhi inezindlela zokwelapha ezimfushane. Futhi ngokuvamile ithathwa njengeqinile ezinhlotsheni ezithile zesikhunta. Kodwa-ke, ingasebenzisana neminye imithi futhi ingase ingafaneleki kuwo wonke umuntu.

I-Griseofulvin inomlando omude wokuphepha futhi ivame ukukhethwa ezinganeni nakubantu abanezimo eziningi zezokwelapha. Isebenza kahle ikakhulukazi ku-scalp ringworm futhi inokusebenzisana okuncane kwemithi kune-terbinafine.

Udokotela wakho uzocabangela izinto ezinjengohlobo lokutheleleka, iminyaka yakho, eminye imithi oyithathayo, nempilo yakho yonke lapho enquma phakathi kwalezi zinketho. Yomibili imithi iyasebenza uma isetshenziswa ngendlela efanele.

Imibuzo Evame Ukubuzwa Mayelana ne-Griseofulvin

Ingabe i-Griseofulvin iphephile ezinganeni?

Yebo, i-griseofulvin ithathwa njengephephile ezinganeni futhi empeleni ingenye yezindlela zokwelapha ezikhethwayo zokutheleleka ngesikhunta ezigulini ze-pediatric. Ivame ukusetshenziswa ikakhulukazi ku-scalp ringworm, evame kakhulu ezinganeni kunabadala.

Umuthi uyatholakala ngesimo esiwuketshezi, okwenza kube lula ukuwunika izingane ezincane ezingakwazi ukugwinya amaphilisi. Ukulinganisa kubalwa ngokucophelela ngokuya ngesisindo somntwana, futhi odokotela banolwazi oluningi lokusebenzisa lo muthi ngokuphepha ezinganeni.

Abazali kufanele baqaphele izingane zabo ngezinto ezingezinhle, ikakhulukazi ukusabela kwesikhumba noma isisu esicasulayo. Iningi lezingane liyawubekezelela kahle umuthi, futhi ukuqeda inkambo ephelele kubalulekile ekuvikeleni ukutheleleka ukuthi kungabuyi.

Ngingenzani uma ngiphuzile i-Griseofulvin eningi ngengozi?

Uma ngabe uthatha i-griseofulvin eningi ngengozi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Nakuba ukweqisa kwe-griseofulvin kungavamile, ukuthatha okuningi kakhulu kungase kubangele imiphumela emibi.

Izimpawu zokweqisa zingase zihlanganise isicanucanu esibi, ukuhlanza, ukudideka, noma ukozela okungavamile. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo uchwepheshe wezempilo noma isikhungo sokulawula ubuthi.

Gcina ibhodlela lemithi nawe uma ufuna usizo ukuze abahlinzeki bezempilo bakwazi ukubona kahle ukuthi uthatheni nokuthi uthathe kangakanani. Uma omunye umuntu emndenini wakho ethatha imithi yakho ngengozi, funa ukunakekelwa kwezempilo ngokushesha.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Griseofulvin?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho yokuthatha imithi.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi. Kunalokho, qhubeka nje neshejuli yakho evamile bese uzama ukuba nokuvumelana okwengeziwe phambili.

Ukusetha izikhumbuzi zansuku zonke ocingweni lwakho noma ukuthatha imithi yakho ngesikhathi esifanayo nomunye umsebenzi wansuku zonke kungasiza ekuvimbeleni imithamo ephuthelwe. Ukuvumelana kubalulekile ekugcineni amazinga asebenzayo emithi emzimbeni wakho.

Ngingayeka nini ukuthatha i-Griseofulvin?

Yeka kuphela ukuthatha i-griseofulvin uma udokotela wakho ekutshela ukuthi wenze njalo, ngisho noma izimpawu zakho zithuthukile noma zinyamalele. Izifo zokungcola zingaba nzima, futhi ukuyeka ukwelashwa ngokushesha kuvame ukuholela ekubuyeni kwesifo.

Udokotela wakho angase afune ukukuhlola noma enze izivivinyo ukuze aqinisekise ukuthi ukutheleleka sekuphelile ngokuphelele ngaphambi kokuyeka ukwelashwa. Ezifweni zezipikili, lokhu kungase kusho ukulinda kuze kube yilapho isipikili esithelelekile sesikhule ngokuphelele futhi sithathelwe indawo yisipikili esinempilo.

Uma uhlangabezana nemiphumela emibi okwenza kube nzima ukuqhubeka nokwelashwa, khuluma nodokotela wakho ngezinkathazo zakho. Bangase bakwazi ukulungisa umthamo wakho noma baphakamise izindlela zokuphatha imiphumela emibi kunokumisa ukwelashwa ngaphambi kwesikhathi.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Griseofulvin?

Ngokuvamile kunconywa ukugwema noma ukunciphisa utshwala ngenkathi uthatha i-griseofulvin. Utshwala bungandisa ingozi yezinkinga zesibindi futhi bungase luqhubekisele phambili eminye imiphumela emibi efana nesiyezi noma isisu esicasukile.

Uma ukhetha ukuphuza, kwenze ngokulinganisela futhi unake indlela ozizwa ngayo. Abanye abantu bathola ukuthi utshwala bubathinta ngamandla ngenkathi bethatha i-griseofulvin, ngakho-ke kuhle ukuqapha.

Khuluma nodokotela wakho mayelana nokusetshenziswa kotshwala, ikakhulukazi uma uthatha eminye imithi noma unezinkinga zesibindi. Bangakunikeza iseluleko esiqondene nawe esisekelwe esimweni sakho esithile kanye nomlando wezempilo.