Yini i-Guanethidine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Guanethidine iyimithi kadokotela esiza ukwehlisa umfutho wegazi ophezulu ngokuvimba izimpawu ezithile zemizwa emzimbeni wakho. Le mithi endala kodwa esebenzayo yomfutho wegazi isebenza ngendlela ehlukile kunezinye izinketho zanamuhla, okuyenza ibe yindlela ekahle uma ezinye izindlela zokwelapha zingasebenzi kahle kuwe.

Ngenkathi i-guanethidine ngokuvamile ingeyona imithi yokuqala odokotela abayinqumayo yomfutho wegazi ophezulu, ingaba yithuluzi elibalulekile ekuphatheni i-hypertension enzima. Ukuqonda ukuthi le mithi isebenza kanjani nokuthi yini ongayilindela kungakusiza ukuthi uzizwe uqiniseka kakhulu ngohlelo lwakho lokwelapha.

Yini i-Guanethidine?

I-Guanethidine ingeyeqembu lemithi ebizwa ngokuthi ama-adrenergic blocking agents. Yenzelwe ngqo ukusiza imithambo yakho yegazi ukuthi iphumule futhi yande, okunciphisa umfutho wegazi ogeleza kuwo.

Le mithi isetshenziswe amashumi eminyaka ukwelapha umfutho wegazi ophezulu, ikakhulukazi ezimweni lapho ezinye izindlela zokwelapha zingasebenzi ngokwanele. Udokotela wakho angase acabangele i-guanethidine uma udinga ukulawulwa okwengeziwe komfutho wegazi ngaphezu kwalokho imithi ejwayelekile engakunikeza kona.

Cabanga nge-guanethidine njengethuluzi elikhethekile ebhokisini lamathuluzi likadokotela wakho. Ngenkathi imithi emisha yomfutho wegazi ivame ukuzanywa kuqala, le mithi endala isengadlala indima ebalulekile ekuphathweni okuphelele komfutho wegazi.

Isetshenziselwani i-Guanethidine?

I-Guanethidine ngokuyinhloko iqondiswe ukwelapha umfutho wegazi ophezulu ophakathi nendawo kuya kowezinga eliphezulu. Ilusizo ikakhulukazi lapho umfutho wakho wegazi usalokhu uphakeme naphezu kokuthatha eminye imithi.

Odokotela bavame ukugcina i-guanethidine ezimweni eziyinselele kakhulu ze-hypertension. Lokhu kungabandakanya izimo lapho uzame khona eminye imithi eminingi yomfutho wegazi ngaphandle kokufeza imigomo yakho yomfutfo wegazi.

Kwezinye izimo, umhlinzeki wakho wokunakekelwa kwezempilo angase akwelule ukuthi usebenzise i-guanethidine njengengxenye yokwelashwa okuhlanganisiwe. Lokhu kusho ukuthi uzoyithatha kanye neminye imithi yokwehlisa umfutho wegazi ukuze uthole ukulawula okungcono kwesimo sakho.

Isebenza Kanjani I-Guanethidine?

I-Guanethidine isebenza ngokuvimba izimpawu zemizwa ezingavame ukubangela ukuthi imithambo yakho yegazi iqine. Uma lezi zimpawu zivinjwa, imithambo yakho yegazi ingakhululeka futhi yande, ivumele igazi ukuthi ligeleze kalula.

Lo muthi uthathwa njengomuthi oqinile wokwehlisa umfutho wegazi ngoba uthinta uhlelo lwakho lwezinzwa oluzwelayo lomzimba. Uhlelo lwezinzwa oluzwelayo lunomthwalo wemfanelo wokuphendula kwakho

Uma uthatha eminye imithi, khuluma nodokotela wakho mayelana nebanga elingcono kakhulu phakathi kwemithamo. Eminye imithi ingase ihlangane ne-guanethidine, ngakho-ke isikhathi singase sibe nomthelela esimweni sakho esithile.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Guanethidine?

Umfutho wegazi ophezulu ngokuvamile uyisimo sesikhathi eside, ngakho-ke cishe uzodinga ukuthatha i-guanethidine isikhathi eside. Abantu abaningi abanomfutho wegazi ophezulu badinga ukuthatha imithi yomfutho wegazi impilo yonke ukuze bagcine amazinga anempilo.

Udokotela wakho uzohlola njalo umfutho wakho wegazi ukuze abone ukuthi imithi isebenza kahle kangakanani. Ngokusekelwe kulokhu kuhlolwa, bangase balungise umthamo wakho noma bacabangele ukwengeza eminye imithi ohlelweni lwakho lokwelapha.

Ungayeki ukuthatha i-guanethidine ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka imithi yomfutho wegazi kungazelele kungabangela umfutho wakho wegazi ukuthi ukhuphuke ngendlela eyingozi, okungaholela ezinkingeni ezinzima.

Uma wena nodokotela wakho ninquma ukuyeka i-guanethidine, bazokwenza uhlelo lokunciphisa kancane umthamo wakho. Le nqubo yokunciphisa isiza ekuvimbeleni izinguquko ezingazelele kumfutho wakho wegazi.

Yiziphi Imiphumela Eceleni Ye-Guanethidine?

Njengayo yonke imithi, i-guanethidine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi okulindelekile kungakusiza ukuthi ubone ukulungiswa okuvamile uma kuqhathaniswa nezimpawu ezikhathazayo.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isiyezi, ikakhulukazi uma usukuma ngokushesha, nokuzizwa ukhathele noma ubuthakathaka. Le miphumela ivame ukuthuthuka njengoba umzimba wakho ulungela imithi emasontweni ambalwa okuqala.

Nawa amanye imiphumela emibi evamile okufanele uyiqaphele:

• Isiyezi noma ukuzizwa unovalo, ikakhulukazi uma umile
• Ukukhathala noma ukuzizwa ukhathele ngokungavamile
• Ukuvaleka kwamakhala noma amakhala avalekile
• Ukuqunjelwa noma izitulo ezixekile
• Ubunzima ekukhishweni kwesidoda emadodeni
• Ubuthakathaka bemisipha noma izinhlungu
• Ukuvuvukala emaqakaleni akho noma ezinyaweni

Lezi zimo ezivamile ezibangelwa imithi zivame ukulawuleka futhi zivame ukuncipha ngokuhamba kwesikhathi. Uma ziqhubeka noma ziba yinkinga, khuluma nodokotela wakho mayelana nokulungiswa okungenzeka ekwelashweni kwakho.

Ngokuvamile, abanye abantu bahlangabezana nemiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukubona:

• Isiyezi esikhulu noma ukuquleka
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile
• Ukuqunjelwa okukhulu okungathuthuki
• Ukuphefumula kanzima noma ukuphelelwa umoya
• Ukuvuvukala okukhulu kobuso, izindebe, ulimi, noma umphimbo
• Ukudideka kwengqondo noma ukucindezeleka

Uma uhlangabezana nanoma yimiphi yale miphumela emibi engathi sína, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Lezi zimpawu zingase zikhombe ekuphenduleni okungathi sína okudinga ukunakekelwa ngokushesha.

Ubani Ongafanele Athathwe I-Guanethidine?

I-Guanethidine ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyibhala. Izimo nezimo ezithile zenza lo muthi ungaphephile.

Akufanele uthathe i-guanethidine uma wazi ukuthi unokungezwani komzimba nomuthi noma yiziphi izithako zawo. Xhumana nodokotela wakho mayelana nanoma yiziphi izindlela zokungezwani komzimba owake waba nazo emithini.

Izimo eziningi zezokwelapha zingase zikwenze ukuthi i-guanethidine ingafaneleki kuwe:

• Ukwehluleka kwenhliziyo noma isifo senhliziyo esibi
• Ukuhlaselwa yinhliziyo noma unhlangothi lwakamuva
• Isifo sezinso esibi
• I-Pheochromocytoma (ithumba elingavamile le-adrenal gland)
• Ukucindezeleka okukhulu noma umlando wemicabango yokuzibulala
• Isifo se-peptic ulcer
• Isifuba somoya noma izinkinga ezinkulu zokuphefumula

Udokotela wakho uzophinda acabangele lezi zimo ngokucophelela ngaphambi kokubhala i-guanethidine, njengoba zingase zidinge ukuqapha okukhethekile noma ukulungiswa komthamo.

Ukukhulelwa nokuncelisa kudinga ukucatshangelwa okukhethekile nge-guanethidine. Umuthi ungawela i-placenta futhi ungase umthinte umntwana wakho osakhula, ngakho xoxa ngazo zonke izinhlelo zokukhulelwa nodokotela wakho.

Amagama e-Brand e-Guanethidine

I-Guanethidine itholakala ngaphansi kwamagama amaningi e-brand, nakuba ivame ukunqunywa njengomuthi ojwayelekile. Igama le-brand elaziwa kakhulu yi-Ismelin, okuyilokhu okwakuyifomula yokuqala yalo muthi.

Amanye amagama e-brand ongahlangana nawo afaka i-Esimil (uma ihlanganiswe ne-hydrochlorothiazide) kanye namafomula ahlukahlukene ajwayelekile. Ikhemisi lakho lingase lithathele indawo i-guanethidine ejwayelekile ngenguqulo yegama le-brand ngaphandle uma udokotela wakho efuna ngqo igama le-brand.

I-guanethidine ejwayelekile iqukethe isithako esifanayo esisebenzayo njengenguqulo yegama le-brand futhi isebenza ngempumelelo. Umehluko omkhulu uvame ukuba ezithakweni ezingasebenzi, okungavamile ukuthi kuthinte ukuthi umuthi usebenza kahle kangakanani.

Ezinye izindlela ze-Guanethidine

Uma i-guanethidine ingakulungele noma ingalawuli umfutho wegazi lakho ngempumelelo, imithi eminingi ehlukile iyatholakala. Imithi yomfutho wegazi yesimanje ivame ukuba nemiphumela emincane futhi ingase ilungele ukuyithatha.

Ama-ACE inhibitors afana ne-lisinopril ne-enalapril avame ukunqunywa njengemithi yomugqa wokuqala yokucindezela kwegazi eliphezulu. Le mithi isebenza ngokukhulula imithambo yegazi futhi ivame ukubekezelelwa kahle abantu abaningi.

Ezinye izindlela udokotela wakho angazicabangela zifaka:

• Ama-calcium channel blockers (njenge-amlodipine noma i-nifedipine)
• Ama-Beta-blockers (njenge-metoprolol noma i-atenolol)
• Ama-Diuretics (njenge-hydrochlorothiazide noma i-furosemide)
• Ama-ARBs noma ama-angiotensin receptor blockers (njenge-losartan noma i-valsartan)
• Imithi emisha ehlanganisiwe equkethe izidakamizwa eziningi zomfutho wegazi

Udktela wakho uzokhetha enye indlela engcono kakhulu ngokusekelwe ezimweni zakho zempilo ezithile, eminye imithi oyithathayo, nokuthi ukwamukela kanjani imiphumela ehlukene engemihle. Ngezikhathi ezithile, inhlanganisela yemithi isebenza kangcono kunomuthi owodwa kuphela.

Ingabe i-Guanethidine Ingcono Kunezinye Izidakamizwa Zegazi?

I-Guanethidine akudingeki ukuthi ingcono noma imbi kunezinye izidakamizwa zomfutho wegazi, kodwa isebenza ngenjongo ethile ekuphathweni komfutho wegazi. Umuthi "ongcono kakhulu" uncike esimweni sakho sempilo kanye nokuthi usabela kanjani ekwelashweni.

Uma iqhathaniswa nemithi emisha yomfutho wegazi, i-guanethidine ivame ukuba nemiphumela eminingi engemihle, ikakhulukazi isiyezi nokukhathala. Kodwa-ke, ingasebenza kahle kakhulu kubantu abangazange basabele kahle kwezinye izindlela zokwelapha.

Imithi yesimanje efana ne-ACE inhibitors kanye ne-calcium channel blockers ngokuvamile izanywa kuqala ngoba inemiphumela embalwa engemihle futhi kulula ukuyibekezelela. I-Guanethidine ivame ukugcinelwa amacala lapho lezi zindlela zokwelapha zokuqala zinganele.

Inzuzo ye-guanethidine amandla ayo okwehlisa umfutho wegazi, ikakhulukazi ezimweni ze-hypertension ezingamelani. Uma umfutho wakho wegazi usahlala uphakeme naphezu kokuthatha eminye imithi eminingi, i-guanethidine ingase ibe yiyo kanye oyidingayo.

Udktela wakho uzocabangela izinto ezinjengobudala bakho, ezinye izimo zempilo, ukusebenza kwezinso, kanye nokusabela kwemithi yangaphambilini lapho enquma ukuthi i-guanethidine ikufanele yini. Umgomo uhlala ukuthola ukwelashwa okuphumelela kakhulu ngemiphumela embalwa engemihle.

Imibuzo Evame Ukubuzwa Mayelana ne-Guanethidine

Ingabe i-Guanethidine Iphephile Kubantu Abanesifo Sikashukela?

I-Guanethidine ingasetshenziswa kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Umuthi ungase uthinte amazinga akho kashukela egazini futhi ngezinye izikhathi ungase ufihle izimpawu zokuxwayisa zikashukela ophansi.

Uma unesifo sikashukela, udokotela wakho uzofuna ukuqapha ushukela wakho wegazi eduze uma uqala ukuthatha i-guanethidine. Kungase kudingeke ukuthi uhlole ushukela wakho wegazi kaningi, ikakhulukazi emasontweni ambalwa okuqala okwelashwa.

Umuthi ungase futhi uthinte ukugeleza kwegazi emilenzeni yakho, okuyinto esivele ikhathaza abantu abanesifo sikashukela. Umhlinzeki wakho wezempilo uzolinganisela lezi zingozi ngokumelene nezinzuzo zokulawulwa okungcono komfutho wegazi.

Kufanele Ngenzeni Uma Ngithatha I-Guanethidine Engakanani Ngengozi?

Uma ngengozi uthatha i-guanethidine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela ukuthi umfutho wakho wegazi wehle ngendlela eyingozi, okuholela ekugajeni okukhulu, ukuquleka, noma ezinye izinkinga ezinzima.

Izimpawu zokuthatha i-guanethidine eningi zihlanganisa ukugajwa okukhulu, ukuzizwa ubuthakathaka, ukukhathala okukhulu, noma ukudideka. Ungalindi ukubona ukuthi lezi zimpawu ziyathuthuka zodwa - funa usizo lwezokwelapha ngokushesha.

Uma kungenzeka, cela othile ahlale nawe ngenkathi ulinde usizo lwezokwelapha. Gwema ukushayela noma ukusebenzisa imishini uma uzizwa ugajwe noma udidekile ngemuva kokuthatha umuthi omningi.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Guanethidine?

Uma uphuthelwa umthamo we-guanethidine, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile.

Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungabangela ukuthi umfutho wakho wegazi wehle kakhulu futhi kukwenze uzizwe ugajwe noma uquleke.

Uma uvame ukukhohlwa ukuthatha umuthi wakho, cabanga ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi. Ukuthatha imithi okuqhubekayo kubalulekile ekulawuleni okuhle komfutho wegazi.

Ngingayeka Nini Ukuthatha I-Guanethidine?

Ungayeki ukuthatha i-guanethidine ngaphandle kokukhuluma nodokotela wakho kuqala. Umfutho wegazi ophezulu ngokuvamile uyisimo sempilo yonke esidinga ukwelashwa okuqhubekayo ukuvimbela izinkinga ezinzima njengokuhlaselwa yinhliziyo noma unhlangothi.

Udokotela wakho angase acabange ukuyeka noma ukushintsha imithi yakho uma umfutho wegazi lakho ulawulwe kahle isikhathi eside futhi wenze izinguquko ezinkulu endleleni yakho yokuphila. Kodwa-ke, lesi sinqumo kufanele senziwe ngaso sonke isikhathi kanye nomhlinzeki wakho wezempilo.

Uma udinga ukuyeka ukuthatha i-guanethidine, udokotela wakho uzokwenza uhlelo lokunciphisa kancane kancane umthamo wakho emasontweni amaningana. Le nqubo yokunciphisa isiza ukuvimbela umfutho wegazi lakho ukuthi ungaqhubeki ngokuzumayo.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Guanethidine?

Kufanele ukhawulele ukusetshenziswa kotshwala ngenkathi uthatha i-guanethidine, njengoba utshwala bungandisa imiphumela yokwehlisa umfutho wegazi yomuthi. Le nhlanganisela ingakwenza uzizwe unesiyezi noma unomuzwa wokukhanya ekhanda kunokujwayelekile.

Uma ukhetha ukuphuza utshwala, yenza kanjalo ngokulinganisela futhi uqaphele kakhulu uma usukuma noma ushintsha izikhundla. Inhlanganisela yotshwala ne-guanethidine ingakwenza uthambekele ekuweni ngenxa yesiyezi.

Xhumana nodokotela wakho mayelana nemikhawulo ephephile yotshwala ngenkathi uthatha i-guanethidine. Bangase batusa ukugwema utshwala ngokuphelele, ikakhulukazi uma uqala ukuthatha umuthi futhi ulungisa imiphumela yawo.