Yini i-Guanfacine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Guanfacine iyimithi kadokotela esiza ukulawula umfutho wegazi kanye nezinkinga ezithile zokunaka. Le mithi emnene kodwa esebenzayo isebenza ngokuthulisa izamukeli ezithile ebuchosheni bakho nasemithanjeni yegazi, okwenza kube lula emzimbeni wakho ukugcina amazinga omfutho wegazi anempilo futhi uthuthukise ukugxila uma kudingeka.

Yini i-Guanfacine?

I-Guanfacine ingeyeqembu lemithi ebizwa ngokuthi ama-alpha-2 agonists, okusho ukuthi isebenza ngokugxila ezamukelini ezithile ohlelweni lwakho lwezinzwa. Cabanga ngayo njengomlawuli omnene osiza umzimba wakho ukuthi uthole ukulinganisela kwawo kwemvelo. Ekuqaleni yathuthukiswa ngenxa yomfutho wegazi ophezulu, odokotela bathola ukuthi futhi isiza izingane kanye nabantu abadala abanezinkinga zokunaka ukungasebenzi kahle (ADHD) ngokuthuthukisa ukugxila nokunciphisa ukuziphatha okungazelelwe.

Umuthi uza ngezindlela ezimbili eziyinhloko: amaphilisi akhishwa ngokushesha omfutho wegazi namaphilisi akhishwa isikhathi eside aklanyelwe ngqo ukwelashwa kwe-ADHD. Zombili lezi zinhlobo zisebenza ngendlela efanayo kodwa zikhishwa ohlelweni lwakho ngamanani ahlukene ukuze ahambisane nezidingo zakho ezithile zezokwelapha.

Isetshenziselwani i-Guanfacine?

I-Guanfacine inezinjongo ezimbili eziyinhloko emithini yesimanje. Kubantu abadala, ilawula ngempumelelo umfutho wegazi ophezulu ngokusiza imithambo yegazi ukuthi iphumule futhi inciphise umsebenzi wenhliziyo. Ezinganeni nakubantu abadala abane-ADHD, ithuthukisa ububanzi bokunaka futhi inciphisa ukuziphatha okungasebenzi noma okungazelelwe okungaphazamisa impilo yansuku zonke.

Udokotela wakho angase akubhalele i-guanfacine yodwa noma kanye neminye imithi, kuye ngesimo sakho esithile. Uma isetshenziselwa i-ADHD, ivame ukuhlanganiswa nemithi ekhuthazayo ukuze kunikezwe ukuphathwa kwezimpawu okubanzi kakhulu. Umuthi usebenza kahle kakhulu kubantu ababa nokugqashuka ngokomzwelo noma abanobunzima bokulawula ukuziphatha.

Ngezinye izikhathi odokotela banikeza i-guanfacine ngezindlela ezingekho emthethweni, njengokusiza ngezinkinga zokulala, ukukhathazeka, noma izimpawu zokuhoxiswa kwezinye izinto. Kodwa-ke, lezi zindlela kufanele zicatshangelwe kuphela ngaphansi kokuqondiswa kwezokwelapha okucophelelayo ngokubheka njalo.

Isebenza Kanjani I-Guanfacine?

I-Guanfacine isebenza ngokwenza ama-alpha-2 receptors ebuchosheni bakho nasemithanjeni yegazi. Lawa ma-receptors asebenza njengama-dimmer switch ohlelweni lwakho lwezinzwa, esiza ukunciphisa ukusebenza ngokweqile ezingxenyeni ezithile zobuchopho. Uma lawa ma-receptors esetshenzisiwe, athumela amasignali akhuthaza ukuzola nokugxila okungcono ngenkathi ehlisa umfutho wegazi.

Lo muthi ubhekwa njengomuthi olungile kunokuba umuthi onamandla. Ukhiqiza izinguquko eziqhubekayo, ezinensayo emzimbeni wakho kunemiphumela emangalisayo esheshayo. Ngomfutho wegazi, ungase uqaphele ukuthuthuka emahoreni ambalwa, kodwa inzuzo ephelele ivame ukuthuthuka emasontweni ambalwa okusetshenziswa okuqhubekayo.

Ngezimpawu ze-ADHD, i-guanfacine ngokuvamile ithatha amasonto angu-1-2 ukukhombisa ukuthuthuka kokuqala, nenzuzo enkulu ngokuvamile evela ngemva kwamasonto angu-4-6 okwelashwa. Umuthi uqhubeka usebenza usuku lonke, unikeza ukukhululeka kwezimpawu okuqhubekayo ngaphandle kokunyuka nokwehla abanye abantu abahlangabezana nakho ngemithi ekhuthazayo.

Kufanele Ngiyithathe Kanjani I-Guanfacine?

Thatha i-guanfacine ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye noma kabili ngosuku kuye ngesimo sakho kanye nokwakheka okuthile. Ifomu lokukhishwa ngokushesha ngokuvamile lithathwa ngesikhathi sokulala ukunciphisa ukulala emini, kuyilapho amaphilisi akhishwe isikhathi eside ngokuvamile athathwa kanye ngosuku ekuseni noma kusihlwa.

Ungathatha i-guanfacine ngokudla noma ngaphandle kokudla, kodwa ukuyithatha ngokudla kungasiza ukunciphisa isisu uma uhlangabezana nanoma yini. Gwinya amaphilisi akhishwe isikhathi eside wonke ngaphandle kokuwachoboza, ukuwahlafuna, noma ukuwaqhekeza, ngoba lokhu kungathinta indlela umuthi okhishwa ngayo emzimbeni wakho. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho ngezinketho ezingezinye.

Ukungaguquguquki kubalulekile nge-guanfacine. Zama ukuyithatha ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo egazini lakho. Uma uyithatha ngenxa yomfutho wegazi, udokotela wakho angase akuqale ngomthamo ophansi bese ewunyusa kancane kancane ukuze athole inani elifanele lomzimba wakho.

Ngingayithatha isikhathi esingakanani i-Guanfacine?

Ubude bokwelashwa nge-guanfacine buqondana ngokuphelele nesimo sakho esithile nokuthi usabela kahle kangakanani emuthini. Ngomfutho wegazi ophezulu, ungase udinge ukuyithatha isikhathi eside njengengxenye yokuqhubeka kwakho nokuphatha impilo yakho. Imithi yomfutho wegazi ivame ukuba yingxenye ehlala njalo yomsebenzi wakho wansuku zonke ukuze ugcine uhlelo lwakho lwe-cardiovascular lusempilweni.

Ukwelashwa kwe-ADHD, isikhathi singahluka kakhulu kumuntu nomuntu. Abanye abantu bayazuza ekuthathweni kwe-guanfacine izinyanga eziningana kuya eminyakeni embalwa, kanti abanye bangase badinge ukwelashwa isikhathi eside. Udokotela wakho uzohlola njalo ukuthi umuthi usebenza kahle kangakanani nokuthi ngabe uhlangabezana nanoma yimaphi imiphumela engemihle.

Ungayeki ukuthatha i-guanfacine ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokuphazima kungabangela umfutho wegazi ophezulu noma ukwanda kwezimpawu ze-ADHD. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo uma udinga ukuyeka ukuthatha umuthi, uqinisekisa ukuthi umzimba wakho ulungela ushintsho ngokuphepha.

Yiziphi Imiphumela Eceleni ye-Guanfacine?

Abantu abaningi bayamukela i-guanfacine kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ulungela umuthi emasontweni ambalwa okuqala kokwelashwa.

Imiphumela emibi ejwayelekile ongase uyithole ihlanganisa ukozela, isiyezi, ikhanda, nokukhathala. Le miphumela ivame ukubonakala kakhulu uma uqala ukuthatha umuthi noma uma umthamo wakho wenyusiwe. Nawa imiphumela emibi ebikwa kaningi:

• Ukozela noma ukulala, ikakhulukazi emasontweni ambalwa okuqala
• Isiyezi lapho usukuma ngokushesha
• Ikhanda elivame ukuba lincane noma libe phakathi nendawo
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Umlomo owomile, ongaphathwa ngokuhlala unamanzi kahle
• Ukuqunjelwa, okuvame ukuthuthuka ngokwanda kwe-fiber kanye nokuthatha amanzi
• Isisu esibuhlungu noma isicanucanu, ikakhulukazi lapho kuqala ukwelashwa

Le miphumela emibi ejwayelekile ivame ukuba ngaphansi kokukhathaza njengoba umzimba wakho ujwayela umuthi. Abantu abaningi bathola ukuthi ukuhlala unamanzi, ukuthola ukuphumula okwanele, nokusukuma kancane ezindaweni zokuhlala noma zokuqamba amanga kungasiza ekuphatheni le miphumela.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha. Ngenkathi lokhu kwenzeka ngezikhathi ezithile, kubalulekile ukuyazi ukuze ukwazi ukufuna usizo uma kudingeka:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okuhamba kancane ngokungavamile noma ukushaya kwenhliziyo okungajwayelekile
• Ushintsho olukhulu lwemizwa noma ukucindezeleka
• Ukucabanga okungamanga noma ukudideka
• Ukuphendula kwesikhumba okukhulu noma ukuqubuka
• Ukuphefumula kanzima noma ubuhlungu besifuba

Uma uhlangabezana nanoma iyiphi yale miphumela emibi ebucayi, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezokwelapha eziphuthumayo. Lezi zindlela zokuphendula azivamile kodwa zidinga ukuhlolwa kwezokwelapha ngokushesha ukuze kuqinisekiswe ukuphepha kwakho.

Ubani Ongafanele Athole i-Guanfacine?

Abantu abathile kufanele bagweme i-guanfacine noma bayisebenzise ngaphansi kokugadwa kwezokwelapha okucophelelayo. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokunikeza lo muthi ukuze aqinisekise ukuthi uphephile esimweni sakho esithile.

Akufanele uthathe i-guanfacine uma unokungezwani komzimba nomuthi noma yiziphi izithako zawo. Abantu abanezimo ezithile zenhliziyo, ikakhulukazi labo abanokushaya kwenhliziyo okuhamba kancane kakhulu noma ukuvinjelwa kwenhliziyo, kungenzeka bangabi ngabantu abafanelekayo kulo muthi. Udokotela wakho cishe uzofuna ukuhlola isigqi senhliziyo yakho ngaphambi kokuqala ukwelashwa.

Ukuqapha okukhethekile kuyadingeka uma unezinkinga zezinso noma zesibindi, ngoba lezi zitho zisiza ekucubunguleni imithi. Abantu abanomlando wokucindezeleka, ukuquleka, noma umfutho wegazi ophansi kakhulu kufanele baxoxe ngalezi zimo nodokotela wabo ngaphambi kokuqala i-guanfacine. Abesifazane abakhulelwe noma abancelisayo kufanele basebenzise lo muthi kuphela uma izinzuzo ezingaba khona ziqeda ngokusobala izingozi.

Amagama e-Guanfacine Brand

I-Guanfacine itholakala ngaphansi kwamagama amaningi ebhrendi, ngalinye lenzelwe ukusetshenziswa okuthile. Amagama ebhrendi ajwayelekile afaka i-Tenex yamaphilisi akhishwe ngokushesha asetshenziswa ikakhulukazi umfutho wegazi, kanye ne-Intuniv yamaphilisi akhishwe isikhathi eside avunyelwe ngokuqondile ukwelashwa kwe-ADHD.

I-Guanfacine ejwayelekile nayo iyatholakala kabanzi futhi iqukethe isithako esifanayo esisebenzayo njengama-brand-name versions. Ikhemisi lakho lingase lithathele indawo ngokuzenzakalelayo inguqulo ejwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lebhrendi. Zombili izinguqulo ezijwayelekile nezegama lebhrendi zisebenza ngokulinganayo uma zisetshenziswa njengoba zibhaliwe.

Ezinye izindlela ze-Guanfacine

Ezinye izindlela eziningi ziyatholakala zombili zokuphatha umfutho wegazi nokwelashwa kwe-ADHD. Ukuze uthole umfutho wegazi ophezulu, ezinye izithako ze-alpha-2 ezifana ne-clonidine zisebenza ngendlela efanayo ne-guanfacine. Ama-ACE inhibitors, ama-beta-blockers, kanye nama-calcium channel blockers amelela amakilasi ahlukene emithi yomfutho wegazi okungenzeka ukuthi udokotela wakho angawacabangela.

Ukwelashwa kwe-ADHD, ezinye izindlela zifaka imithi ekhuthazayo efana ne-methylphenidate noma ama-amphetamine, asebenza ngezindlela ezihlukene kune-guanfacine. Izinketho ezingakhuthazi zifaka i-atomoxetine, ethinta ama-neurotransmitters ahlukene ebuchosheni. Udokotela wakho angakusiza ukuthi uhlole lezi zindlela uma i-guanfacine ingafaneleki ezidingweni zakho.

Ukukhetha okunye kuncike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabela kanjani ezinhlotsheni ezahlukene zemithi. Abanye abantu benza ngcono ngama-stimulants, kanti abanye bazuzisa kakhulu ngezinketho ezingezona ze-stimulant njenge-guanfacine.

Ingabe i-Guanfacine ingcono kune-Clonidine?

Kokubili i-guanfacine ne-clonidine bangama-alpha-2 agonists asebenza ngezindlela ezifanayo, kodwa banomehluko obalulekile. I-Guanfacine ivame ukuhlala isikhathi eside ohlelweni lwakho, okusho ukuthi ukulinganisa okungavamile nemiphumela ezinzile usuku lonke. Abantu abaningi bathola ukuthi i-guanfacine ibangela ukuthula okuncane kune-clonidine.

I-Clonidine isikhona isikhathi eside futhi itholakala emazingeni amaningi, okuhlanganisa nezithambiso zokulethwa kwemithi okungaguquki. Kodwa-ke, i-guanfacine ingase ithuthukiswe kangcono ngabanye abantu, ikakhulukazi labo abathola ukozela okuningi nge-clonidine.

Ukukhetha

Kumele Ngenzeni Uma Ngithatha I-Guanfacine Eningi Ngengozi?

Uma ngengozi uthatha i-guanfacine eningi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela ukwehla okuyingozi kwengcindezi yegazi, ukozela okukhulu, kanye nokushaya kwenhliziyo okuhamba kancane. Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini, ngoba ukuhlolwa kwezokwelapha okusheshayo kubalulekile.

Ngesikhathi ulindele isiqondiso sezokwelapha, lalela phansi futhi gwema ukuvuka ngokushesha. Vumela othile ahlale nawe uma kungenzeka, futhi ungaqhubi imoto noma usebenzise imishini. Uma uhlangabezana nezimpawu ezinzima njengobunzima bokuphefumula, ubuhlungu besifuba, noma ukuquleka, shayela izinsiza eziphuthumayo ngokushesha.

Kumele Ngenzeni Uma Ngiphuthelwa Umthamo We-Guanfacine?

Uma uphuthelwa umthamo we-guanfacine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungabangela ukwehla okuyingozi kwengcindezi yegazi.

Ngezindlela zokukhishwa okwandisiwe, ukuphuthelwa umthamo kungase kuthinte ukulawulwa kwezimpawu zakho ngalolo suku. Zama ukusungula umkhuba okusiza ukuthi ukhumbule ukuthatha imithi yakho ngokuqhubekayo, njengokusetha izikhumbuzi zocingo noma ukuyithatha ngesikhathi esifanayo nomunye umsebenzi wansuku zonke.

Ngingayeka Nini Ukuthatha I-Guanfacine?

Isinqumo sokuyeka i-guanfacine kufanele senziwe ngaso sonke isikhathi ngokubonisana nodokotela wakho. Ukuze kulawulwe ingcindezi yegazi, kungase kudingeke ukuthi uqhubeke nomuthi isikhathi eside ukuze ugcine amazinga e-blood pressure anempilo. Ukuze kulashwe i-ADHD, abanye abantu bangase bakwazi ukuyeka umuthi ngemva kwezinyanga noma iminyaka yokwelashwa okuphumelelayo.

Udokotela wakho uzokusiza ukuthi unciphise kancane umthamo emasontweni amaningana ukuze uvimbele imiphumela yokubuyela emuva. Ukuyeka kungazelelwe kungabangela ukukhuphuka okuyingozi kwengcindezi yegazi noma ukwanda kwezimpawu ze-ADHD. Ukuqokwa okuvamile kokulandela kuzosiza ukunquma isikhathi esifanele sanoma yiziphi izinguquko zemithi.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Guanfacine?

Utshwala bungakhuphula ukozela kanye nemiphumela yokugajwa ye-guanfacine, okwenza kube yingozi ukushayela noma ukwenza imisebenzi edinga ukuqapha. Zombili lezi zinto zinganciphisa umfutho wegazi, futhi ukuzihlanganisa kungase kubangele ukwehla komfutho wegazi okuyingozi kwabanye abantu.

Uma ukhetha ukuphuza utshwala ngenkathi uthatha i-guanfacine, yenza kanjalo ngokulinganisela futhi uqaphele kakhulu ngemisebenzi edinga ukuxhumana noma ukuqapha. Khuluma nodokotela wakho mayelana nemikhawulo ephephile yokusetshenziswa kotshwala ngokusekelwe emthozini wakho othile kanye nesimo sezokwelapha. Abanye abantu bangase badinge ukugwema utshwala ngokuphelele ngenkathi bethatha lo muthi.