Yini i-Histamine H2 Antagonist? Izimpawu, Izimbangela, & Nokwelashwa Ekhaya

Ama-histamine H2 antagonists yimithi evimba ama-histamine receptors esiswini sakho ukuze kuncishiswe ukukhiqizwa kwe-asidi. Le mithi, eyaziwa ngokuthi ama-H2 blockers, isiza ukwelapha izimo ezinjenge-heartburn, i-acid reflux, nezilonda zesisu ngokunciphisa inani le-asidi elenziwa isisu sakho.

Ungase wazi le mithi ngamagama ajwayelekile afana ne-ranitidine (Zantac), i-famotidine (Pepcid), noma i-cimetidine (Tagamet). Zisebenza ngokugxila kuma-receptors athile emgodleni wakho wesisu ovame ukusabela ku-histamine, ikhemikhali yemvelo ebangela ukukhiqizwa kwe-asidi.

Yini i-Histamine H2 Antagonist?

I-histamine H2 antagonist uhlobo lomuthi ovimbela i-histamine ekubopheni kuma-H2 receptors esiswini sakho. Lapho i-histamine inamathisela kula ma-receptors, ithumela isisu sakho ukuthi sikhiqize i-asidi yokugaya ukudla.

Cabanga ngama-H2 receptors njengamalokhi kumaseli akho esisu, futhi i-histamine njengokhiye olungena kula malokhi. Lapho i-histamine

Ngamafomu omlomo, ungase uzwe ukuncipha kancane kancane kokusha esifubeni sakho noma emqaleni. Abanye abantu baqaphela ukuthi bangadla ukudla okwakubangela ukungakhululeki ngaphambili ngaphandle kokuzwa izinga elifanayo lezimpawu ezihlobene ne-asidi.

Amafomu e-IV noma okujova asebenza ngokushesha, ngokuvamile enikeza ukukhululeka ngemizuzu engama-15-30. Ngeke uzizwe umuthi uqobo, kodwa ungase uqaphele ukuthi isisu sakho sizizwa singena-asidi kancane noma sicasukile ngokushesha kunezinhlobo zomlomo.

Yini ebangela isidingo sama-H2 Antagonists?

Izimo eziningana ezivamile zenza isidingo sokwelashwa nge-H2 antagonist. Ukuqonda lezi zimbangela eziyisisekelo kungakusiza ukuthi usebenzisane nomhlinzeki wakho wezempilo ukuze uthole indlela esebenza kahle kakhulu.

Isifo se-Gastroesophageal reflux (GERD) singesinye sezizathu ezivame kakhulu zokuthi abantu badinge le mithi. Lokhu kwenzeka lapho i-asidi yesisu igeleza njalo ibuyela e-esophagus yakho, okubangela isilungulela kanye nomonakalo ongaba khona emgqeni womphimbo wakho.

Izilonda ze-Peptic, okuyizilonda ezivulekile esiswini sakho noma emgqeni wamathumbu amancane, ngokuvamile zidinga ama-H2 antagonists ukuze ziphole kahle. Lezi zilonda zingavela ngenxa yokutheleleka ngamagciwane (ikakhulukazi i-H. pylori), ukusetshenziswa kwemithi ebanga ubuhlungu isikhathi eside njenge-ibuprofen, noma ukukhiqizwa kwe-asidi ngokweqile.

Nawa amakhondishini amakhulu angase adinge ukwelashwa nge-H2 antagonist:

• Isifo se-Gastroesophageal reflux (GERD)
• Izilonda ze-Peptic esiswini noma e-duodenum
• I-Zollinger-Ellison syndrome (isimo esingavamile esibangela ukukhiqizwa kwe-asidi ngokweqile)
• I-Erosive esophagitis (ukuqubuka nokulimala kwe-esophagus)
• I-Gastritis (ukuqubuka komugqa wesisu)
• Ukuvimbela izilonda zokucindezeleka ezigulini ezigulayo kakhulu
• I-Dyspepsia (ukugaya ukudla okungapheli)

Ngokuvamile, odokotela babhala le mithi ngezifo ezingavamile njenge-mastocytosis, lapho umzimba wakho ukhiqiza i-histamine eningi kakhulu, noma njengengxenye yokwelashwa kwezifo ezithile zokungezwani komzimba ezingaphenduli kuma-antihistamines ajwayelekile.

Ukusebenzisa i-H2 Antagonist kuyisibonakaliso noma isimpawuli sani?

Lapho udokotela wakho ebhala i-H2 antagonist, ngokuvamile kubonisa ukuthi unesimo esibandakanya ukukhiqizwa kwe-asidi esiswini esiningi noma ukulimala okuhlobene ne-asidi ohlelweni lwakho lokugaya ukudla. Isidingo sale mithi sivame ukukhombisa izinkinga zempilo yokugaya ukudla ezidinga ukunakekelwa.

Ukusetshenziswa njalo kwama-H2 antagonists ngokuvamile kuphakamisa ukuthi ubhekene nezinkinga ezingapheli ezihlobene ne-asidi kunokusha kwenhliziyo okwenzeka ngezikhathi ezithile. Umhlinzeki wakho wezempilo cishe unqume ukuthi izimpawu zakho zivame ngokwanele noma zinzima ngokwanele ukuthi zidingeke ukwelashwa okuqhubekayo kokucindezela i-asidi.

Izimo eziqondile ezilashwa yile mithi zihlanganisa:

• Isifo se-gastroesophageal reflux esingapheli esidinga ukulawulwa kwe-asidi kwesikhathi eside
• Isifo se-peptic ulcer, ikakhulukazi uma sibangelwa ukutheleleka kwamagciwane e-H. pylori
• I-Barrett's esophagus, isimo esingaphambi komdlavuza esibangelwa ukuchayeka kwe-asidi okungapheli
• I-Zollinger-Ellison syndrome, lapho imithombo yezifo ibangela ukukhiqizwa kwe-asidi okwedlulele
• I-Gastrinoma, imithombo yezifo engavamile evuselela ukukhiqizwa kwe-asidi
• I-Systemic mastocytosis, lapho i-histamine eningi ithinta izinhlelo eziningi zomzimba
• I-Gastritis engapheli evela ezintweni ezihlukahlukene ezihlanganisa izimo ze-autoimmune

Ezindaweni zasemtholampilo, ama-IV H2 antagonists avame ukukhombisa ukuthi isiguli sisenkingeni enkulu yokuthuthukisa izilonda zokucindezeleka ngenxa yokugula okubucayi, ukuhlinzwa okukhulu, noma ukungenisa umoya ngomshini isikhathi eside. Lokhu kusetshenziswa kokuvimbela kusiza ukuvikela umugqa wesisu ngezikhathi zokucindezeleka okukhulu ngokomzimba.

Ingabe imiphumela ye-H2 Antagonist inganyamalala yodwa?

Imiphumela ye-H2 antagonists ingeyesikhashana futhi izonyamalala uma uyeka ukuthatha imithi. Iningi le-H2 blockers yomlomo lisebenza amahora angu-4-12, kuye ngomuthi othile kanye nomthamo, ngaphambi kokuthi ukukhiqizwa kwe-asidi yesisu sakho kubuyele emazingeni ajwayelekile.

Nokho, isimo esingaphansi esidinga ukwelashwa nge-H2 antagonist singase silungiswe noma singalungiswa ngokwaso. Ukushisa kwesifuba okulula okuvela ekudleni ngokweqile kungase kuthuthuke ngokushintsha ukudla, kodwa izimo ezingapheli njenge-GERD noma izilonda ze-peptic ngokuvamile zidinga ukuphathwa kwezokwelapha okuqhubekayo.

Abanye abantu bathola ukuthi bangagcina banciphisa noma bayeke ama-H2 antagonists ngokwenza izinguquko zokuphila. Ukuncipha kwesisindo, izinguquko zokudla, kanye nokuphathwa kwengcindezi ngezinye izikhathi kungathuthukisa izimpawu ezihlobene ne-asidi ngokwanele kangangokuthi imithi ingabi yadingeka.

Umzimba wakho awuthuthukisi ukuncika unomphela kuma-H2 antagonists, kodwa ukuwayeka kungazelelwe kungase kubangele ukwanda kwesikhashana ekukhiqizweni kwe-asidi okubizwa ngokuthi i-rebound hyperacidity. Lokhu ngokuvamile kuthatha izinsuku ezimbalwa kuya emavikini njengoba isisu sakho sizivumela emuva kumaphethini aso ajwayelekile okukhiqizwa kwe-asidi.

Zingaphathwa kanjani izimpawu ezihlobene ne-asidi ekhaya?

Amasu amaningana asekhaya angasiza ukunciphisa izimpawu ezihlobene ne-asidi futhi anganciphisa isidingo sakho sama-H2 antagonists ngokuhamba kwesikhathi. Lezi zindlela zisebenza kahle uma zihlanganiswe nokwelashwa kwezokwelapha kunokuba zisetshenziswe njengezithathela ngokuphelele imithi ebekiwe.

Ukuguqulwa kokudla kuvame ukuhlinzeka ngokuqeda okukhulu ezimpawini ezihlobene ne-asidi. Ukugwema ukudla okubangela izinto ezinjengezitya ezinongwe, izithelo ze-citrus, utamatisi, ushokoledi, kanye ne-caffeine kungasiza ukunciphisa ukukhiqizwa kwe-asidi futhi kunciphise iziqephu ze-reflux.

Nawa amasu okuphatha asekhaya asebenzayo ongawazama:

• Yidla ukudla okuncane, okuvame ukudliwa esikhundleni sokudla okukhulu
• Gwema ukulala kungakapheli amahora amathathu ngemva kokudla
• Phakamisa ikhanda lombhede wakho ngamasentimitha angu-6-8
• Gcina isisindo esinempilo ukunciphisa ingcindezi esiswini sakho
• Yeka ukubhema, njengoba kwandisa ukukhiqizwa kwe-asidi futhi kunciphisa i-esophageal sphincter
• Nciphisa ukusetshenziswa kotshwala, ikakhulukazi iwayini nobhiya
• Gqoka izingubo ezixekile okhalweni nasesiswini sakho
• Lawula ukucindezeleka ngezindlela zokuphumula noma ukuzivocavoca njalo
• Hlafuna uswidi ngemva kokudla ukuze ukwandise ukukhiqizwa kwamathe futhi unciphise i-asidi

Imithi yemvelo efana netiye likajinja, i-chamomile, noma amanani amancane e-baking soda emanzini ingase inikeze impumuzo yesikhashana kwabanye abantu. Kodwa-ke, lokhu kufanele kugcwalise, hhayi ukufaka esikhundleni, ukwelashwa kwezokwelapha kwezimo ezingamahlala-mahala.

Khumbula ukuthi ngenkathi lawa maqhinga asekhaya engasiza kakhulu, asebenza kahle kakhulu njengengxenye yohlelo lokwelapha olubanzi oluhlanganisa ukunakekelwa kwezokwelapha okufanele uma kudingeka.

Yini ukwelashwa kwezokwelapha kwezimo ezidinga ama-H2 Antagonists?

Ukwelashwa kwezokwelapha ngama-H2 antagonists kuhilela ukukhetha imithi efanele, umthamo, nendlela yokulethwa ngokusekelwe esimweni sakho esithile nobukhulu bezimpawu. Umhlinzeki wakho wokunakekelwa kwezempilo uzolungisa uhlelo lokwelapha ukuze abhekane nezidingo zakho ngazinye nezinkinga zempilo eziyisisekelo.

Ukwelashwa ngomlomo, ama-H2 antagonists avamile afaka i-famotidine (Pepcid), evame ukukhethwa ngenxa yokusebenzisana okuncane kwemithi, kanye ne-cimetidine (Tagamet), eyayingenye yezinto zokuqala ze-H2 blockers ezathuthukiswa. I-Ranitidine yayithandwa ngaphambili kodwa isusiwe ezimakethe eziningi ngenxa yokukhathazeka ngokuphepha.

Izindlela zokwelapha ziyahlukahluka ngokuya ngesimo sakho:

• I-GERD: Ngokuvamile iqala ngemithamo yomlomo kanye noma kabili ngosuku, ethathwa imizuzu engama-30-60 ngaphambi kokudla
• Izilonda ze-Peptic: Ngokuvamile zidinga imithamo ephezulu kabili ngosuku amasonto ama-4-8, ngezinye izikhathi ihlanganiswe nama-antibiotics
• I-Zollinger-Ellison syndrome: Kungadingeka imithamo ephezulu kakhulu noma ukumnika okuqhubekayo kwe-IV
• Ukuvimbela izilonda zokucindezeleka: Ngokuvamile kuhilela ukuphathwa kwe-IV ezindaweni zasemtholampilo
• Ukwelashwa kokugcina: Imithamo ephansi ethathwa isikhathi eside ukuvimbela ukuphindeka kwezimpawu

Amafomu okujova kanye ne-IV agcinelwe izimo ezithile lapho imithi yomlomo ingafaneleki. Lokhu kufaka phakathi iziguli ezingakwazi ukugwinya, labo abanezimpawu ezinzima ezidinga ukucindezelwa kwe-asidi okusheshayo, noma abantu abasezigumbini zokunakekelwa okukhulu abasengozini yezilonda zokucindezeleka.

Udokotela wakho angahlanganisa ama-H2 antagonists nezinye izindlela zokwelapha njengama-proton pump inhibitors (PPIs) ezimweni ezinzima kakhulu, ama-antibiotics ezifweni ze-H. pylori, noma imithi evikelayo efana ne-sucralfate yokuphulukisa izilonda.

Kufanele ngibone nini udokotela ngezimpawu ezidinga ama-H2 Antagonists?

Kufanele ubone udokotela uma uhlangabezana nokusha kwenhliziyo okuvamile noma i-acid reflux ngaphezu kwamasonto amabili ngesonto, noma uma ama-antacids angaphezu kwe-counter engakunikezi impumuzo eyanele. Lezi zimpawu zingase zibonise isimo esingathi sína esidinga ukuhlolwa kanye nokwelashwa okuchwepheshile.

Izimpawu ezithile zokuxwayisa zidinga ukunakekelwa kwezokwelapha ngokushesha futhi akufanele zinganakwa. Lezi zimpawu zingase zibonise izinkinga ezingathi sína ezidinga ukunakekelwa okuphuthumayo kunokuzelapha ngama-H2 antagonists.

Funani ukunakekelwa kwezokwelapha ngokushesha uma nihlangabezana nalokhu:

• Ubuhlungu obukhulu besifuba obungase ludideke nokusha kwenhliziyo
• Ubunzima bokugwinya noma ukuzwa sengathi ukudla kubhajwe emqaleni wakho
• Ukuphalaza igazi noma izinto ezibukeka njengomhlaba wekhofi
• Izihlalo ezimnyama, ezinamathelayo noma igazi elibomvu ngokugqamile emnyakeni
• Ubuhlungu obukhulu besisu, ikakhulukazi uma kungazelelwe noma kuya ngokuya
• Ukuncipha kwesisindo okungachazeki kanye nezimpawu zokugaya ukudla
• Isicanucanu esiqhubekayo nokuhlanza
• Izimpawu eziphazamisa ukulala noma imisebenzi yansuku zonke

Kufanele futhi uxhumane nomhlinzeki wakho wezempilo uma ubesebenzisa ama-antagonists e-H2 angaphezu kwekhawunta isikhathi esingaphezu kwamasonto amabili ngaphandle kokuthuthuka, noma uma izimpawu zakho zibuyela ngokushesha ngemva kokuyeka imithi.

Ukuqokwa okulandelayo njalo kubalulekile uma usebenzisa ama-antagonists e-H2 isikhathi eside, njengoba udokotela wakho ezofuna ukuqapha ukusabela kwakho ekwelashweni futhi abheke noma yimaphi imiphumela engemihle noma izinkinga.

Ziyini izici eziyingozi zokudinga ama-H2 Antagonists?

Izici eziningana zingakhuphula amathuba akho okuthuthukisa izimo ezidinga ukwelashwa nge-H2 antagonist. Ukuqonda lezi zici eziyingozi kungakusiza ukuthi uthathe izinyathelo zokuvimbela futhi uqaphele lapho ukunakekelwa kwezokwelapha okuchwepheshile kungase kube usizo.

Iminyaka idlala indima ebalulekile, njengoba izinkinga ezihlobene ne-asidi ziba njalo njengoba sikhula. Imisipha evimbela i-reflux ye-asidi ingase ibe buthakathaka ngokuhamba kwesikhathi, futhi umugqa wesisu ungase ube sengozini enkulu yokulimala kusuka ku-asidi kanye nemithi ethile.

Izici zokuphila zithonya kakhulu ingozi yakho yokuthuthukisa izimo ezihlobene ne-asidi:

• Ukukhuluphala noma isisindo esiningi, okwandisa ingcindezi esiswini
• Ukubhema, okunciphisa ukukhiqizwa kwamathe futhi kunciphise i-esophageal sphincter
• Ukusetshenziswa njalo kotshwala, ikakhulukazi ngobuningi obukhulu
• Ukusetshenziswa njalo kwama-NSAID (njenge-ibuprofen noma i-aspirin) ngezinhlungu ezingapheli
• Indlela yokuphila enokucindezeleka okuphezulu noma ukuphathwa kokucindezeleka okunganele
• Amaphethini okudla angajwayelekile noma ukweqa ukudla njalo
• Ukudla ukudla okuningi okubangela (okunezinongo, okune-asidi, noma ukudla okunamafutha)

Izimo zezokwelapha nezinto ezenza ingozi yakho ikhuphuke zihlanganisa:

• I-Hiatal hernia, lapho ingxenye yesisu iphushwa ngedayaphragmu
• Ukukhulelwa, ngenxa yezinguquko zamahomoni nokwanda kwengcindezi yesisu
• Isifo sikashukela, esingathinta ukukhipha isisu futhi sandise ingozi yokutheleleka
• Ukutheleleka ngamabhaktheriya e-Helicobacter pylori
• Umlando womndeni wama-ulcer e-peptic noma umdlavuza wesisu
• Izimo ze-Autoimmune ezithinta uhlelo lokugaya ukudla
• Ukugula okubucayi okudinga ukwelashwa kweyunithi yokunakekelwa okukhulu

Ezinye izimo ezingavamile zofuzo njenge-Zollinger-Ellison syndrome noma i-mastocytosis nazo zingakhuphula kakhulu isidingo sakho semithi ecindezela i-asidi, nakuba lokhu kuthinta abantu abambalwa kakhulu.

Ziyini izinkinga ezingaba khona zokusebenzisa i-H2 Antagonist?

Abantu abaningi babekezelela kahle ama-antagonist e-H2, kodwa njengayo yonke imithi, ingabangela imiphumela emibi nezinkinga kwabanye abantu. Ukuqonda lezi zinkinga ezingaba khona kukusiza ukuthi ubone ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi ejwayelekile ivamise ukuba mnene futhi ingahlanganisa ikhanda, isiyezi, isifo sohudo, noma ukuqunjelwa. Le miphumela ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini, ngokuvamile phakathi nezinsuku ezimbalwa kuya emavikini ambalwa ngemva kokuqala ukwelashwa.

Izinkinga eziqondene kakhulu zingase zivele ngokusebenzisa isikhathi eside noma kubantu abathile:

• Ukuntuleka kwe-Vitamin B12 ngenxa yokuncipha kwe-asidi yesisu edingeka ekumunceni kwe-B12
• Ukwanda kwengozi yokutheleleka okuthile ngenxa yomphumela wokuvikela we-asidi yesisu encishisiwe
• Ukusebenzisana kwemithi, ikakhulukazi ne-cimetidine, engathinta eminye imithi
• Izinkinga zezinso ngokusebenzisa isikhathi eside, ikakhulukazi kubantu abadala
• Izinkinga zesibindi ezingavamile kodwa ezinzima, ikakhulukazi nge-cimetidine
• Ukudideka noma izinguquko zengqondo, ikakhulukazi ezigulini ezindala noma lezo ezinezifo zezinso

Abanye abantu bangase babe nokwanda kwe-asidi lapho beyeka ama-antagonists e-H2 ngokuzumayo ngemva kokusebenzisa isikhathi eside. Lokhu kwanda okwesikhashana ekukhiqizweni kwe-asidi kuvame ukuxazululwa emasontweni ambalwa kodwa kungabangela izimpawu ezingakhululeki.

Ngokungavamile kakhulu, ukusabela okukhulu komzimba kungase kwenzeke, okuhlanganisa ukuqubuka kwesikhumba, ubunzima bokuphefumula, noma ukuvuvukala kobuso nomphimbo. Lokhu kusabela kudinga ukunakekelwa kwezokwelapha ngokushesha nokuyeka umuthi.

Ukuphathwa kwe-IV kuthwala izingozi ezengeziwe njengokutheleleka endaweni yokujova, ukucasuka kwemithambo, noma izinkinga ezivela emgqeni we-IV ngokwawo, nakuba lokhu kungavamile uma kulandelwa izinqubo ezifanele zezokwelapha.

Ingabe ama-H2 Antagonists alungile noma amabi ku-GERD?

Ama-H2 antagonists ngokuvamile alunge kakhulu ekwelapheni i-GERD futhi anikeza ukukhululeka okusebenzayo kubantu abaningi abanalesi simo. Basebenza ngokunciphisa ukukhiqizwa kwe-asidi yesisu, okuqondisa ngqo enye yezimbangela eziyinhloko zezimpawu ze-GERD njengokusha kwenhliziyo kanye ne-acid reflux.

Ku-GERD emnene kuya kwesilinganiselo, ama-H2 antagonists avame ukunikeza ukulawulwa okuhle kakhulu kwezimpawu ezinemiphumela emincane kunemithi eqinile yokucindezela i-asidi. Basiza ikakhulukazi abantu abanezimpawu zasebusuku, njengoba bengahlinzeka ngamahora angu-8-12 okuncishiswa kwe-asidi.

Izinzuzo zama-H2 antagonists e-GERD zihlanganisa:

• Ukunciphisa ngempumelelo ukuvama nokuba nzima kokusha kwenhliziyo
• Ukuphulukiswa kokucasuka okuncane kanye nokuvuvukala kwe-esophageal
• Ukuvimbela izigameko ze-acid reflux, ikakhulukazi ebusuku
• Ngokuvamile kuyabekezeleleka kahle ngemiphumela emincane kunama-PPI
• Itholakala ngaphandle kwekhawunta ukuze itholakale kalula
• Akungenzeki ukuthi kubangele izinkinga zesikhathi eside kunemithi eqinile

Nokho, ama-H2 antagonists kungenzeka anganele nge-GERD eqinile noma amacala ayinkimbinkimbi. Abanye abantu abanolaka olukhulu lwe-esophageal noma i-Barrett's esophagus bangase badinge imithi eqinile efana nama-proton pump inhibitors ukuze bathole ukuphulukiswa okwanele nokulawulwa kwezimpawu.

Ukuphumelela kwama-H2 antagonists ngezinye izikhathi kungancipha ngokuhamba kwesikhathi njengoba umzimba wakho ukhula ukubekezelela umuthi. Lokhu akusho ukuthi bayalimaza, kodwa udokotela wakho angase adinge ukulungisa umthamo wakho noma ashintshele kwenye indlela yokwelapha.

Yini imiphumela ye-H2 Antagonist engase ididaniswe nayo?

Imiphumela yama-H2 antagonists ngokuvamile iyacashile, ngakho-ke mancane amathuba okuthi adidaniswe nezinye izimo. Nokho, kokubili izinzuzo nemiphumela emibi yale mithi ngezinye izikhathi kungadidaniswa nezinye izinkinga zempilo noma imiphumela yemithi.

Ukusizwa kwezimpawu ezivela kuma-H2 antagonists kungase kufihle izimo ezingaphansi ezinzima. Isibonelo, uma unezinhlungu esifubeni ezivela ezinkingeni zenhliziyo, umuthi ungase unciphise ukungakhululeki okuhlobene ne-asidi esifubeni, okungenzeka ukuthi kukwenze ucabange ukuthi izimpawu zakho zenhliziyo zithuthukile lapho zingakabi njalo.

Imiphumela emibi evela kuma-H2 antagonists ingadidaniswa nezinye izimo:

• Ikhanda lingase libangelwe ukucindezeleka, ukushoda kwamanzi emzimbeni, noma eminye imithi
• Isiyezi singase lididaniswe nezinkinga zendlebe yangaphakathi noma izinguquko zomfutho wegazi
• Ushintsho ekugayeni ukudla njengokuhuda lungase lubangelwe ukudla noma eminye imithi
• Ukukhathala noma ukudideka (ikakhulukazi ezigulini ezindala) kungase kudidaniswe nokucindezeleka noma i-dementia
• Ushintsho ekusebenzeni kwezinso lungase lubangelwe ukuguga noma ezinye izimo zempilo

Ngezinye izikhathi, abantu badida ukuthuthuka kancane kancane kwezimpawu zabo nokuphola kwemvelo kunokuba baqaphele ukuthi imithi iyasebenza. Lokhu kungaholela ekuyekeni ukwelashwa ngaphambi kwesikhathi futhi kube nokubuyela kwezimpawu.

Ngokuphambene, uma ama-H2 antagonists engasebenzi ngempumelelo, abantu bangase bacabange ukuthi abanayo inkinga ehlobene ne-asidi lapho empeleni bedinga olunye uhlobo lokwelashwa noma imithi eqinile.

Ezimweni ezingavamile, imiphumela emibi engathi sína njengezinkinga zesibindi ingase ididaniswe nezinye izimo ezifana nezifo ezibangelwa amagciwane noma izinkinga ze-gallbladder, yingakho ukuqapha njalo kubalulekile kubasebenzisi besikhathi eside.

Imibuzo evame ukubuzwa mayelana nama-H2 Antagonists

Ngingawathatha ama-H2 antagonists neminye imithi?

Ama-H2 antagonists amaningi angathathwa ngokuphepha neminye imithi, kodwa ezinye izinto ezingase zenzeke ziyenzeka. I-Cimetidine inokusebenzisana okuningi kwemithi futhi kungathinta indlela umzimba wakho oqhubekisa ngayo eminye imithi efana ne-warfarin, i-phenytoin, kanye nemithi ethile yokucindezeleka.

Njalo tshela umhlinzeki wakho wezempilo ngayo yonke imithi, izithasiselo, kanye nemithi etholakala ngaphandle kwekhawunta oyithathayo. Bangahlola ukusebenzisana okungenzeka futhi balungise imithamo noma isikhathi uma kunesidingo ukuqinisekisa ukwelashwa okuphephile nokuphumelelayo.

Kuthatha isikhathi esingakanani ukuthi ama-H2 antagonists asebenze?

Ama-antagonists e-H2 omlomo ngokuvamile aqala ukusebenza ngaphakathi kwemizuzu engama-30-60, nemiphumela ephezulu yenzeka ngemuva kwehora elingu-1-3 ngemuva kokuthatha umuthi. Ungase uqaphele ukuncipha kokusha kwenhliziyo noma izimpawu ze-acid reflux kungakapheli ihora ngemuva kokuthatha umthamo wokuqala.

Amafomu e-IV asebenza ngokushesha okukhulu, ngokuvamile enikeza ukukhululeka ngemizuzu engu-15-30. Kodwa-ke, kungase kuthathe izinsuku eziningana kuya emavikini okusetshenziswa njalo ukuzwa izinzuzo ezigcwele zokuphulukisa izimo ezinjengezilonda noma i-esophagitis.

Ngingayeka yini ukuthatha ama-antagonists e-H2 ngokuzumayo?

Ngokuvamile ungaqeda ama-antagonists amaningi e-H2 ngaphandle kwemiphumela yokuhoxiswa engathi sína, kodwa kungcono ukubonisana nomhlinzeki wakho wezempilo kuqala. Abanye abantu bazwa ukukhiqizwa kwe-acid okubuyayo izinsuku ezimbalwa kuya emavikini ngemuva kokuyeka, okungabangela ukwanda okwesikhashana kwezimpawu.

Uma ubuthatha ama-antagonists e-H2 isikhathi eside, udokotela wakho angase ancome ukunciphisa umthamo kancane kancane kunokuyeka kungazelelwe. Le ndlela ingasiza ekunciphiseni izimpawu zokubuyela emuva futhi iqinisekise ukuthi isimo sakho esingaphansi sihlala sizinzile.

Ingabe ama-antagonists e-H2 aphephile ngesikhathi sokukhulelwa?

Amanye ama-antagonists e-H2, ikakhulukazi i-famotidine, athathwa njengaphephile ngesikhathi sokukhulelwa lapho izinzuzo zidlula izingozi. Kodwa-ke, kufanele njalo uthintane nomhlinzeki wakho wezempilo ngaphambi kokuthatha noma yimuphi umuthi ngesikhathi sokukhulelwa noma ngenkathi uncelisa.

Udokotela wakho uzocabangela isimo sakho esithile, ubukhulu bezimpawu zakho, kanye nezingozi ezingaba khona nezinzuzo kuwe nakubantwana bakho lapho enquma indlela yokwelapha ephephe kunazo zonke yezimo ezihlobene ne-acid ngesikhathi sokukhulelwa.

Uyini umehluko phakathi kwama-antagonists e-H2 kanye nama-proton pump inhibitors?

Ama-antagonists e-H2 kanye nama-proton pump inhibitors (PPIs) womabili anciphisa i-asidi yesisu, kodwa asebenza ngezindlela ezihlukene. Ama-antagonists e-H2 avimba ama-histamine receptors, kuyilapho ama-PPIs eqondisa ngqo amaphampu akhiqiza i-asidi emangqamuzaneni esisu.

Ama-PPI ngokuvamile anamandla kakhulu futhi anikeza ukucindezelwa kwe-asidi okuhlala isikhathi eside, kodwa ama-H2 antagonists ngokuvamile anezinye izinto ezingezinhle zesikhathi eside. Umhlinzeki wakho wokunakekelwa kwezempilo uzosiza ekunqumeni ukuthi yiluphi uhlobo lomuthi olufaneleka kakhulu isimo sakho esithile nezidingo zakho.