Yini i-Histamine Intradermal Route: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Histamine intradermal route iyisivivinyo sezokwelapha lapho kufakwa khona inani elincane le-histamine ngaphansi nje kwendawo yesikhumba sakho. Le nqubo isiza odokotela ukuthi bahlole ukuthi isimiso somzimba wakho sokuzivikela sikuphendula kahle kangakanani kuma-allergen futhi singathola izimo ezithile zokungezwani komzimba. Isivivinyo sivame ukwenziwa endaweni yezokwelapha elawulwayo futhi sinikeza ulwazi olubalulekile mayelana nokuphendula komzimba wakho i-histamine.

Yini i-Histamine Intradermal Route?

Isivivinyo se-histamine intradermal sihlanganisa ukufaka inani elincane le-histamine solution ngqo ezingxenyeni ezingaphezulu zesikhumba sakho. Cabanga ngayo njengendlela elawulwayo yokubona ukuthi umzimba wakho usabela kanjani kule khemikhali yemvelo edlala indima ebalulekile ekuphenduleni komzimba okungalungile.

Ngesikhathi salesi sivivinyo, udokotela wakho usebenzisa inaliti enhle kakhulu ukubeka i-histamine ngaphansi nje kwendawo yesikhumba sakho. Ukujova kudala iqhubu elincane eliphakanyisiwe, elifana nokulunywa iminyevu, okusiza ochwepheshe bezokwelapha ukuthi bahlole ukuzwela kwesikhumba sakho nokuphendula komzimba.

Lesi sivivinyo sithathwa njengamathuluzi okuxilonga kunokwelashwa. Ivame ukusetshenziswa kanye nezinye izivivinyo zokungezwani komzimba ukuze kutholwe isithombe esiphelele sokuthambekela komzimba wakho okungalungile futhi isize ekuqondiseni izinqumo zokwelapha.

Isetshenziselwani i-Histamine Intradermal Route?

Odokotela ngokuyinhloko basebenzisa lesi sivivinyo ukuxilonga nokuhlola izimo zokungezwani komzimba, ikakhulukazi uma ezinye izivivinyo zingazange zinikeze izimpendulo ezicacile. Ilusizo ikakhulukazi ekuhloleni ikhono lesikhumba sakho lokusabela kuma-allergen.

Isivivinyo sisebenza njengokulawula okuhle kumaphaneli wokuhlola ukungezwani komzimba. Uma uhlolwa ama-allergen athile afana ne-pollen, uthuli, noma ukudla, ukujova kwe-histamine kuqinisekisa ukuthi isikhumba sakho singakwazi ngempela ukukhiqiza ukusabela okungalungile. Uma isikhumba sakho singasabeli ku-histamine, kusikisela ukuthi eminye imiphumela emibi ingase ingathembeki.

Abahlinzeki bezempilo nabo basebenzisa leli vivinyo ukuhlola izifo ezithile zesimiso somzimba sokuzivikela. Kwezinye izimo, abantu abanezinhlelo zokuzivikela ezithintekile kungenzeka bangasabeli ngendlela ejwayelekile ku-histamine, okungabonisa izimo zempilo eziyisisekelo ezidinga ukunakekelwa.

Ngaphezu kwalokho, lolu vivinyo lusiza odokotela ukuthi bahlole ukusebenza kahle kwemithi ye-antihistamine. Ngokubona ukuthi isikhumba sakho sisabela kanjani ku-histamine ngenkathi usebenzisa le mithi, udokotela wakho angathola ukuthi ukwelashwa kwakho kwamanje kusebenza kahle yini.

Isebenza Kanjani Indlela Ye-Histamine Intradermal?

Lolu vivinyo lusebenza ngokwethula i-histamine ngqo emzimbeni wakho, lapho luqala khona ukusabela komzimba okungahambisani nokujwayelekile. I-Histamine iyikhemikhali umzimba wakho owenza ngokwemvelo ngesikhathi sokusabela komzimba okungahambisani nokujwayelekile, ngakho umjovo ulingisa okwenzekayo uma uhlangana ne-allergen.

Uma isijovwe, i-histamine ibopha kuma-receptors athile kumaseli akho esikhumba nasemithanjeni yegazi. Lokhu kubopha kubangela izimpawu zakudala zokusabela komzimba okungahambisani nokujwayelekile: ububomvu, ukuvuvukala, nokuluma endaweni yokujova. Amandla alokhu kusabela atshela udokotela wakho imininingwane ebalulekile mayelana nokuzwela kwesimiso sakho sokuzivikela.

Uvivinyo lubhekwa njengolunamandla ngokulinganisela mayelana namandla okuxilonga. Ngenkathi izwela kakhulu kunokuhlolwa kwesikhumba, akunamandla kangako kunezinye izindlela zokuhlola ukungezwani komzimba. Lokhu kulinganisela kwenza kube wusizo ekutholeni ukungezwani komzimba okungenzeka kungaveli ezivivinyweni ezithambile.

Ukusabela kwesikhumba sakho kuvame ukuvela phakathi kwemizuzu eyi-15-20 ngemuva komjovo. Ithimba lezempilo lizokala usayizi wanoma iyiphi iqhubu eliphakanyisiwe (elibizwa ngokuthi i-wheal) nobubomvu obuzungezile ukuze kutholwe amandla okusabela kwakho.

Kufanele Ngithathe Kanjani Indlela Ye-Histamine Intradermal?

Awuyithathi ngempela le mithi ngomqondo wendabuko njengoba inikezwa uchwepheshe wezempilo ngesikhathi senqubo yezokwelapha. Kodwa-ke, kunezinqubo ezibalulekile okufanele uzilandele ukulungiselela ukuhlolwa.

Ngaphambi kokuba uqokwe, kuzodingeka uyeke ukuthatha imithi ye-antihistamine isikhathi esithile. Udokotela wakho uzokutshela ngqo ukuthi kufanele ulinde isikhathi esingakanani, kodwa ngokuvamile kungama-3-7 izinsuku ngaphambi kokuhlolwa. Lokhu kuqinisekisa ukuthi isikhumba sakho singaphendula kahle emthonjeni we-histamine.

Ngosuku lokuhlolwa kwakho, gqoka izingubo ezikhululekile ezivumela ukufinyelela okulula engalweni yakho noma emhlane, lapho kuzonikezwa khona umjovo. Akudingeki ukuthi ugweme ukudla noma ukuphuza, kodwa kungcono ukuhlala unamanzi futhi udle ngokujwayelekile ukuze uzizwe ungcono kakhulu ngesikhathi senqubo.

Ngesikhathi sokuhlolwa, uzohlala ngokukhululeka ngenkathi umhlinzeki wezempilo ehlanzela indawo yokujova futhi asebenzise inaliti encane ukubeka i-histamine ngaphansi kwesikhumba sakho. Umjovo wangempela uthatha imizuzwana embalwa nje futhi uzizwa ufana nokugwaza okufushane.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Histamine Intradermal Route?

Lokhu kuyisivivinyo sokuxilonga esisodwa, hhayi ukwelashwa okuqhubekayo okuthatha njalo. Inqubo yonke, okuhlanganisa nesikhathi sokubuka, ngokuvamile ithatha imizuzu engama-30-45 ehhovisi likadokotela wakho.

Umjovo ngokwawo wenzeka ngemizuzwana embalwa nje, kodwa kuzodingeka ulinde imizuzu engama-15-20 ukuthi isikhumba sakho siphendule. Ngesikhathi lesi, ithimba lezempilo lizobheka indawo yokujova futhi likale noma yikuphi ukusabela okwenzekayo.

Ngemuva kokuthi ukuhlolwa kuqediwe futhi imiphumela irekhodiwe, akukho imithi eqhubekayo okufanele ithathwe. Udokotela wakho uzoxoxa ngemiphumela nawe futhi achaze ukuthi asho ukuthini ngokuqonda kwakho nokuhlela ukwelashwa.

Uma udinga ukuhlolwa okuphindaphindiwe kokungezwani komzimba esikhathini esizayo, udokotela wakho angase ancome lokhu kuhlolwa futhi. Kodwa-ke, ukuhlolwa ngakunye kuyinqubo ehlukile, eyodwa kunokuba yingxenye yeshejuli yokwelashwa eqhubekayo.

Yiziphi Imiphumela Eceleni ye-Histamine Intradermal Route?

Abantu abaningi bazizwa kuphela imiphumela emincane, elindelekile endaweni yokujova ngoba lolu vivinyo lwenzelwe ukudala ukusabela okungahleliwe okulawulwayo. Lezi zimpendulo ezijwayelekile empeleni yizinto odokotela abazifunayo ukuze bahlole amasosha akho omzimba.

Nawa amaphendulo ajwayelekile, alindelekile ongase uwathole ngesikhathi nangemva kokuhlolwa:

• Ububomvu nokuvuvukala endaweni yokujova okubonakala phakathi kwemizuzu engu-15-20
• Ukuqina noma ukungakhululeki okuncane lapho i-histamine yayijovwe khona
• Ibhampa eliphakanyisiwe noma i-wheal engase ihlale imizuzu engu-30-60
• Ukuthamba okuncane lapho uthinta indawo yokujova

Lezi zimpendulo zijwayelekile futhi ziyingxenye elindelekile yokuhlolwa. Zivame ukunyamalala emahoreni ambalwa ngaphandle kokwelashwa okudingekayo.

Imiphumela engavamile kodwa engenzeka ihlanganisa ukusabela kwesikhumba okusabalale kakhulu ngaphandle kwendawo yokujova. Abanye abantu bangase bathuthukise iziqephu ezibomvu ezengeziwe noma ukuluma kwezinye izingxenye zomzimba wabo, nakuba lokhu kungavamile.

Ukusabela okukhulu komzimba akujwayelekile kakhulu ngalolu vivinyo ngoba inani le-histamine elisetshenziswayo lincane kakhulu futhi lilawulwa. Nokho, abantu abanezifo ezingathi sína noma amasosha omzimba abuthakathaka bangase bathole ukusabela okuqinile kunokulindelekile.

Ngokungavamile kakhulu, abanye abantu bangase bazizwe benesiyezi, isicanucanu, noma bezizwa bephenduka ngesikhathi sokuhlolwa. Lokhu kungenzeka kakhulu uma uzwela kakhulu ezinqubweni zezokwelapha noma ungadlanga muva nje.

Ubani Ongafanele Athole Indlela Ye-Histamine Intradermal?

Amaqembu amaningana abantu kufanele agweme lolu vivinyo noma axoxe ngezindlela ezingezinye nomhlinzeki wabo wezempilo. Okubaluleke kakhulu ukuthi ngabe njengamanje uthatha imithi engaphazamisa imiphumela.

Akufanele ube nalo lolu vivinyo uma njengamanje usebenzisa ama-antihistamines, njengoba le mithi izovimba ukusabela kwesikhumba okulindelekile. Udokotela wakho uzokweluleka ukuthi uyeke le mithi izinsuku eziningana ngaphambi kokuhlolwa, kodwa uma ungenakho ukuwayeka ngokuphepha, ezinye izindlela zokuhlola zingase zinconywe.

Abantu abanesifuba esikhulu, esingazinzile kufanele basondele kulolu vivinyo ngokuqapha. Ngenkathi umjovo we-histamine ukhona endaweni ethile, ungaqala izinkinga zokuphefumula kulabo abanemigudu yomoya ebucayi kakhulu. Udokotela wakho uzohlola ukulawulwa kwakho kwesifuba ngaphambi kokuqhubeka.

Uma unezimo zesikhumba ezisebenzayo njenge-eczema noma i-dermatitis endaweni yokujova ehleliwe, ukuhlolwa kungase kudingeke ukuthi kuhlehliswe. Lezi zimo zingaphazamisa ukuhumusha imiphumela futhi zingase zibangele ukungakhululeki okwengeziwe.

Abesifazane abakhulelwe ngokuvamile bayelulekwa ukuthi bagweme izinqubo zezokwelapha ezingadingekile, nakuba lolu vivinyo lubhekwa njengoluphephile. Udokotela wakho uzohlola izinzuzo zokuxilongwa ngokumelene nanoma yiziphi izingozi ezingaba khona kuwe nomntwana wakho.

Abantu abasebenzisa imithi ethile ngaphandle kwama-antihistamines bangase futhi badinge ukuguqula ukwelashwa kwabo. Ama-beta-blockers, ama-tricyclic antidepressants, kanye neminye imithi ingathinta indlela isikhumba sakho esisabela ngayo ku-histamine.

Amagama Omkhiqizo we-Histamine Intradermal Route

I-Histamine yokuhlolwa kwe-intradermal ngokuvamile ilungiswa yizinkampani zemithi ezikhethekile ezigxile ezintweni zokuhlola ukungezwani komzimba. Ngokungafani nemithi ejwayelekile ongayithatha ekhemisi, lezi zixazululo zivame ukunikezwa ngokuqondile ezikhungweni zokunakekelwa kwezempilo.

Amagama omkhiqizo ajwayelekile afaka i-Histatrol, esetshenziswa kakhulu emitholampilo yokungezwani komzimba nezibhedlela. Lokhu kulungiswa okujwayelekile kuqinisekisa imiphumela evumelana nayo kuzo zonke izikhungo zokuhlola ezihlukene kanye nabanikezeli bezempilo.

Ezinye izikhungo zezokwelapha zisebenzisa izixazululo ze-histamine ezenziwe ngokwezifiso ezenziwa ngamakhambi okuhlanganisa. Lokhu kulungiswa kulandela imihlahlandlela eqinile ukuqinisekisa ukuphepha nokusebenza kahle, yize kungase kungabi namagama athile omkhiqizo.

Ukugxila nokulungiswa kwe-histamine kungahluka kancane phakathi kwabakhiqizi, kodwa abahlinzeki bezempilo baqeqeshwe ukuhumusha imiphumela ngokusekelwe kumkhiqizo othile abawusebenzisayo. Lokhu kuqinisekisa ukuxilongwa okunembile kungakhathaliseki ukuthi yimuphi umkhiqizo osetshenzisiwe.

Ezinye Izindlela Zokuhlolwa Kwe-Histamine Intradermal

Uma ukuhlolwa kwe-histamine intradermal kungakulungele, izindlela eziningana zokuhlola ezingezinye zingahlinzeka ngolwazi olufanayo lokuxilonga. Udokotela wakho angasiza ekunqumeni ukuthi iyiphi inketho esebenza kahle kakhulu esimweni sakho esithile.

Ukwelashwa kwesikhumba yizona ezivamile kakhulu futhi azihlaseli ngaphezu kwemijovo ye-intradermal. Ngesikhathi sokuhlolwa, izinto ezincane ze-allergens zibekwa ebusweni besikhumba sakho, futhi isikhumba sigwazwa ngobumnene ukuvumela ukungena okuncane. Ngenkathi ingezweli ngaphezu kokuhlolwa kwe-intradermal, ukuhlolwa kokugwaza kuvame ukwanele ekuhloleni kokuqala kwe-allergy.

Ukuhlolwa kwegazi, njengokuhlolwa kwe-IgE ethile, kungalinganisa ama-antibodies akho omzimba we-allergic ngaphandle kokubandakanyeka kwesikhumba. Lokhu kuhlolwa kuwusizo ikakhulukazi uma ungenakukwazi ukuyeka ukuthatha ama-antihistamines noma unezimo ezinzima zesikhumba ezingaphazamisa ukuhlolwa kwesikhumba.

Ukwelashwa kwe-patch kungenye indlela enye esebenza kahle ekutholeni izindlela zokuphendula ezinqenqezelayo, njenge-contact dermatitis. Izinto ezincane ze-allergens ezingaba khona zisetshenziswa kuma-patches ahlala esikhumbeni sakho amahora angama-48-72, okuvumela odokotela ukuthi babone izindlela zokuphendula ezinqenqezelayo.

Kwezinye izimo, udokotela wakho angase ancome ukuhlolwa kwezinselelo, lapho uveza khona kuma-allergens asolwayo ngaphansi kokuqondiswa kwezokwelapha okulawulwayo. Lokhu kuhlolwa kuvame ukugcinwa ezimweni lapho ezinye izindlela zokuhlola zingazange zinikeze izimpendulo ezicacile.

Ingabe i-Histamine Intradermal Route Ingcono Kunezivivinyo Zokuhlola Isikhumba?

Kokubili ukuhlolwa kwe-histamine intradermal kanye nokuhlolwa kokuhlola isikhumba kunendawo yabo ekuxilongweni kokungezwani komzimba, futhi akukho noyedwa 'ongcono' kunomunye. Ukukhetha kuncike esimweni sakho sezokwelapha esithile kanye nolwazi oludingwa udokotela wakho.

Izivivinyo ze-Intradermal zizwela kakhulu kunezivivinyo zokuhlola isikhumba, okusho ukuthi zingathola ukungezwani komzimba okungenzeka kungaveli ekuhlolweni okuthambile kokuhlola. Lokhu kwanda kokuzwela kwenza ukuhlolwa kwe-intradermal kube yigugu ikakhulukazi lapho odokotela besola ukungezwani komzimba kodwa izivivinyo zokuqala zokuhlola zaphuma zingalungile.

Kodwa-ke, ukuzwela okuphezulu kwezivivinyo ze-intradermal kusho ukuthi maningi amathuba okuthi zikhiqize imiphumela engamanga. Ngezinye izikhathi ukuhlolwa kungase kusikisela ukungezwani komzimba lapho empeleni ungenazo izimpawu ezibalulekile ngokomtholampilo ezivela kulowo allergen.

Izivivinyo zokuhlola isikhumba azihlaseli kangako futhi zikhululekile kubantu abaningi. Zishesha futhi ukwenza futhi zingahlola ama-allergen amaningi ngesikhathi esisodwa. Ukuze kuhlolwe ukungezwani komzimba kokuqala, izivivinyo zokuhlola zivame ukuba yindawo yokuqala ekhethwayo.

Udokotela wakho ngokuvamile uzoqala ngezivivinyo zokuhlola isikhumba bese eqhubekela ekuhlolweni kwe-intradermal kuphela uma kudingeka ukutholwa okuzwela kakhulu. Le ndlela yesinyathelo ngesinyathelo isiza ukulinganisa ukunemba nokunethezeka kwesiguli kanye nokonga izindleko.

Imibuzo Evame Ukubuzwa Mayelana ne-Histamine Intradermal Route

Q1. Ingabe i-Histamine Intradermal Route iphephile kubantu abanezifo zenhliziyo?

Ngokuvamile, ukuhlolwa kwe-histamine intradermal kuthathwa njengokuphephile kubantu abanezifo zenhliziyo, kodwa i-cardiologist yakho kanye ne-allergist kufanele bahlele ukunakekelwa kwakho. Inani le-histamine elisetshenziswayo lincane kakhulu futhi litholakala endaweni ethile, ngakho-ke akunakwenzeka ukuthi lithinte umsebenzi wenhliziyo yakho ngokuphawulekayo.

Kodwa-ke, uma usebenzisa ama-beta-blockers ngenxa yesimo senhliziyo yakho, le mithi ingaphazamisa imiphumela yokuhlolwa futhi ingase ifihle ukusabela kwesikhumba sakho okuvamile ku-histamine. Odokotela bakho bazodinga ukulinganisa ukubaluleka kokuhlolwa kokungezwani komzimba nezingozi zokulungisa imithi yakho yenhliziyo okwesikhashana.

Abantu abanezimo zenhliziyo ezinzima noma labo abaye bahlaselwa yinhliziyo yamuva kufanele baxoxe ngesikhathi sokuhlolwa kokungezwani komzimba nethimba labo lezempilo. Ngenkathi ukuhlolwa ngokwako kunengozi encane, noma iyiphi inqubo yezokwelapha kufanele icatshangelwe ngokucophelela uma ulawula izinkinga zenhliziyo ezinzima.

Q2. Kufanele Ngenzeni Uma Ngisebenzisa I-Histamine Eningi Ngengozi?

Njengoba lokhu kuhlolwa kwenziwa ochwepheshe bezempilo abaqeqeshiwe endaweni yezokwelapha, ukweqisa ngengozi akunakwenzeka. I-histamine ilinganiswa ngaphambili ngemithamo emincane kakhulu, ephephile, futhi ngeke uziphathise wena imithi.

Uma ngasizathu simbe uthole i-histamine eningi kunaleyo obuyihlosile, ithimba lezempilo lizokuqapha ngokushesha nganoma yiziphi izindlela ezingavamile. Baqeqeshwe ukubona nokuphatha noma yiziphi izinkinga ezingase zivele ezinqubweni zokuhlolwa.

Izimpawu ze-histamine eningi ngokuvamile zizofaka ukusabela kwesikhumba okwanda kakhulu, ukuluma okukhulu, noma okungenzeka ukungakhululeki kokugaya ukudla. Esimweni esingenzeka kakhulu, ithimba lakho lezokwelapha linemithi kanye nemithetho elungele ukusiza ukuphatha noma yiziphi izindlela.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Histamine Intradermal Route?

Lo mbuzo awusebenzi kahle ekuhlolweni kwe-histamine intradermal njengoba kuyinqubo eyodwa yokuxilonga kunokuba imithi oyithatha njalo. Awukwazi "ukuphuthelwa umthamo" ngoba kukhona umjovo owodwa kuphela onikezwa ngesikhathi sokuqokwa kwakho.

Uma uphuthelwa i-aphoyintimenti yakho ehleliwe yokuhlolwa, vele uthinte ihhovisi likadokotela wakho ukuze ulungiselele kabusha. Akukho okwenzeka ngokomthetho ngokuqeda ukuhlolwa, nakuba kungase kulibazise ukuxilongwa kwakho nokuhlela ukwelashwa.

Khumbula ukulandela imiyalelo yangaphambi kokuhlolwa uma ulungiselela kabusha, ikakhulukazi mayelana nokuyeka imithi ye-antihistamine isikhathi esidingekayo ngaphambi kosuku lwakho olusha lwe-aphoyintimenti.

Q4. Ngingayeka nini Ukuthatha i-Histamine Intradermal Route?

Njengoba lokhu kuyisivivinyo esisodwa sokuxilonga kunokwelashwa okuqhubekayo, akukho lapho okumele kumiswe khona okumele kucatshangelwe. Uma ukuhlolwa sekuqediwe futhi imiphumela irekhodiwe, inqubo isiphelile.

Ngemuva kokuhlolwa, ungaqala ngokushesha ukuthatha noma yimiphi imithi ye-antihistamine okwakudingeka uyeke ngaphambili, ngaphandle uma udokotela wakho ekunikeza imiyalelo ehlukile. Akukho imithi eqhubekayo okufanele iyekwe noma yehliswe.

Imiphumela yokujova i-histamine ngokuvamile iyaphela emahoreni ambalwa, futhi akukho imithi esele ohlelweni lwakho okudingeka ihlanzwe noma iyekwe.

Q5. Ngingashayela ngemuva kokuthola i-Histamine Intradermal Test?

Abantu abaningi bangashayela ngokuphepha ngemuva kokuhlolwa kwe-histamine intradermal ngoba inqubo ngokuvamile ayibangeli ukozela noma iphazamise ikhono lakho lokusebenzisa imoto. I-histamine ijojwa endaweni futhi ngokuvamile ayithinti ukuqapha kwakho kwengqondo noma ukuxhumana kwakho.

Noma kunjalo, uma uhlangabezana nanoma yiziphi izimpendulo ezingavamile ngesikhathi sokuhlolwa njengokuthi isiyezi, isicanucanu, noma ukuzwa sengathi uyaphela amandla, kufanele ulinde kuze kube yilapho lezi zimpawu zinyamalala ngokuphelele ngaphambi kokushayela. Ithimba lakho lezempilo lizohlola ukuthi uzizwa kanjani ngaphambi kokuthi ushiye isikhungo.

Abanye abantu bangase bazizwe bekhathazekile kancane noma becindezelekile ngemuva kwezinqubo zezokwelapha, ezingathinta izinga labo lokunethezeka ngokushayela. Thembela emizweni yakho mayelana nokuthi uzizwa ngathi usukulungele ukushayela, futhi unganqikazi ukucela othile ukuthi akuphuthume uma uzizwa ungaqinisekile.