Yini i-Histrelin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Histrelin iyikhambi le-synthetic hormone elisiza ukulawula izimo ezithile ezihlobene ne-hormone kubantwana nakubantu abadala. Lo muthi onamandla usebenza ngokumisa ukukhiqizwa kwama-hormone emvelo omzimba wakho, okungaba usizo olukhulu ekwelapheni izimo ezinjengokuthomba ngaphambi kwesikhathi ezinganeni noma umdlavuza wendlala yesinye oqhubekayo emadodeni.

Uzothola i-histrelin njengento encane efakwe ngaphansi kwesikhumba sakho, lapho ikhipha khona imithi ngokuqhubekayo ngokuhamba kwesikhathi. Le ndlela isho ukuthi akudingeki ukhathazeke ngamaphilisi ansuku zonke noma imijovo ejwayelekile, okwenza ukwelashwa kube lula kakhulu kuwe nomndeni wakho.

Isetshenziselwani i-Histrelin?

I-Histrelin iphatha izimo ezimbili eziyinhloko ezithinta amazinga e-hormone emzimbeni wakho. Ezinganeni, isiza ukuphatha ukuthomba okuqala ngaphambi kwesikhathi, okuyilapho ukuthomba kuqala ngaphambi kwesikhathi (ngaphambi kweminyaka engu-8 kumantombazane noma iminyaka engu-9 kumafana).

Kubantu abadala, i-histrelin isetshenziselwa ukwelapha umdlavuza wendlala yesinye oqhubekayo ngokuvimba ukukhiqizwa kwe-testosterone. Le hormone ingakhuthaza ukukhula kwamaseli omdlavuza wendlala yesinye, ngakho ukunciphisa amazinga e-testosterone kusiza ukunciphisa ukuqhubeka komdlavuza.

Udokotela wakho angase futhi acabangele i-histrelin kwezinye izimo ezihlobene ne-hormone, nakuba lokhu kuyizinto ezisetshenziswa kakhulu. Umuthi ubaluleke kakhulu ngoba unikeza ukulawulwa kwe-hormone okuqhubekayo isikhathi eside.

Isebenza Kanjani i-Histrelin?

I-Histrelin isebenza ngokulingisa i-hormone yemvelo ebuchosheni bakho ebizwa nge-GnRH (i-gonadotropin-releasing hormone). Uma uqala ukwelashwa, empeleni ikhulisa ukukhiqizwa kwe-hormone okwesikhashana, kodwa-ke ivala imboni yama-hormone yomzimba wakho.

Cabanga ngayo njengokulayisha ngokweqile i-circuit breaker - ukuqubuka kokuqala kubangela ukuthi uhlelo luvalwe ngokuphelele. Le nqubo ngokuvamile ithatha amasonto angu-2-4 ukufinyelela umphumela ogcwele, ngesikhathi lapho ungase uqaphele izinguquko zesikhashana.

Umuthi uthathwa njengonamandla kakhulu, unikeza ukucindezelwa okunamandla nokuthembekile kwamahomoni. Lawa mandla yiwona kanye awenza asebenze kahle ekwelapheni izimo ezinzima okuyelashwa ngazo.

Ngingawuthatha kanjani i-Histrelin?

I-Histrelin iza njengento encane yokufakelwa ezobekwa udokotela wakho ngaphansi kwesikhumba sengalo yakho engenhla ngesikhathi senqubo esheshayo ehhovisi. Ngeke kudingeke ukuthi wenze lutho olukhethekile ukulungiselela - akukho ukuzila ukudla noma imikhawulo yokudla okudingekayo.

Inqubo yokufakelwa ithatha imizuzu embalwa nje futhi isebenzisa i-anesthesia yendawo ukukugcina ukhululekile. Udokotela wakho uzokwenza ukusikeka okuncane, afake okufakelwayo, bese evala indawo ngesibopho esincane.

Ngemuva kokuthi okufakelwayo kufakwe, ungabuyela emisebenzini ejwayelekile phakathi nosuku olulodwa noma ezimbili. Okufakelwayo kuzosebenza ngokuqhubekayo izinyanga eziyi-12, kukhulule imithi kancane emzimbeni wakho ngaphandle komzamo ovela kuwe.

Kufanele ngiyithathe isikhathi esingakanani i-Histrelin?

Ubude bokwelashwa kwe-histrelin buqondene ngokuphelele nesimo sakho esithile nokuthi usabela kanjani emuthini. Kubantwana abaneminyaka yobudala ngaphambi kwesikhathi, ukwelashwa kuvame ukuqhubeka kuze kube yilapho befika eminyakeni efanele yokuthi intsha ejwayelekile iqale kabusha.

Abantu abadala abanomdlavuza wendlala yesinye bangase badinge ukwelashwa kwesikhathi eside, ngezinye izikhathi iminyaka eminingana. Udokotela wakho uzoqapha intuthuko yakho ngezivivinyo zegazi ezijwayelekile nokuhlolwa ukuze anqume ubude obufanele bakho.

Okufakelwayo kuhlala izinyanga eziyi-12 ngqo, ngemuva kwalokho udokotela wakho uzokususa futhi angase afake okusha uma ukwelashwa okuqhubekayo kudingeka. Lesi sikhathi sinembile impela, ngakho ukugcina umkhondo wosuku lwakho lokufakelwa kubalulekile.

Yiziphi Imiphumela Eceleni ye-Histrelin?

Njenganoma yimuphi umuthi onamandla, i-histrelin ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Imiphumela emibi evame kakhulu ihlobene nezinguquko zamahomoni umuthi azidalayo emzimbeni wakho.

Nansi imiphumela emibi ongase uyithole, iqala ngaleyo ejwayelekile kakhulu:

• Ukushisa okukhulu noma imizwa engazelelwe yokufudumala
• Ushintsho lwemizwa noma ukucasuka
• Ukucindezeleka kwekhanda
• Ukukhathala noma ukudinwa
• Ukuphendula endaweni yokujova njengobubomvu noma ukuvuvukala
• Ushintsho ekusebenzeni ngokocansi noma intshisekelo
• Ushintsho lwesilinganiso somzimba
• Ukuphazamiseka kokulala

Le miphumela ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi ezinyangeni ezimbalwa zokuqala. Udokotela wakho angakusiza ukuthi ulawule noma yiziphi izimpawu ezingakhululekile eziqhubekayo.

Ezinye izimpawu ezingavamile kodwa ezingathi sína zingabandakanya izinguquko zokuminyana kwamathambo ekusetshenzisweni kwesikhathi eside, izinguquko ezinzima zemizwa, noma ukusabela komzimba ngaphandle kokulawuleka. Noma lezi zinto zingavamile, kubalulekile ukuxoxa nganoma yiziphi izimpawu ezikhathazayo nodokotela wakho ngokushesha.

Ubani Ongafanele Athole i-Histrelin?

I-Histrelin ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuncoma lokhu kwelashwa. Abantu abanezimo ezithile noma izimo kufanele bagweme lo muthi.

Akufanele usebenzise i-histrelin uma unokungezwani komzimba nomuthi noma ukwelashwa okufanayo kwamahomoni. Abesifazane abakhulelwe noma abancelisa ngamabele kufanele futhi bagweme lo muthi, njengoba ungathinta amazinga amahomoni ngezindlela ezingase zilimaze umntwana osakhulayo.

Udokotela wakho uzophinda aqaphele ngokunquma i-histrelin uma unezimo ezithile zenhliziyo, ukucindezeleka okukhulu, noma i-osteoporosis. Lezi zimo zingase zibe zimbi ngokwelashwa kokucindezelwa kwamahomoni.

Amagama Omkhiqizo we-Histrelin

I-Histrelin itholakala ngaphansi kwamagama amabili omkhiqizo amakhulu: i-Vantas ne-Supprelin LA. I-Vantas ivame ukusetshenziselwa ukwelapha umdlavuza wendlala yesinye kubantu abadala, kuyilapho i-Supprelin LA ivame ukunqunywa ezinganeni ezinokuvuthwa ngaphambi kwesikhathi.

Yomibili imithi iqukethe isithako esifanayo esisebenzayo kodwa yenziwe ngendlela ehlukile kancane ukuze isetshenziswe ngendlela ethile. Udokotela wakho uzokhetha inguqulo efanele kakhulu ngokusekelwe esimweni sakho nezidingo zakho.

Ezinye izindlela ze-Histrelin

Eminye imithi eminingi inganikeza imiphumela efanayo yokucindezela amahomoni uma i-histrelin ingakulungele. Lezi ezinye izindlela zihlanganisa i-leuprolide (Lupron), i-goserelin (Zoladex), kanye ne-triptorelin (Trelstar).

Ezinye zalezi ezinye izindlela ziza ngemijovo yanyanga zonke noma yekota kunokuthi zibe ama-implants onyaka. Udokotela wakho angase ancome enye indlela uma ukhetha uhlelo oluhlukile lokulinganisa noma uma uhlangabezana nemiphumela emibi nge-histrelin.

Ukukhetha phakathi kwale mithi kuvame ukuncika esimweni sakho esithile, okuthandayo ukuphila, nokuthi uyikwazi kangakanani ukubekezelela inketho ngayinye. Ngayinye inezinzuzo zayo kanye nezinto okufanele zicatshangelwe.

Ingabe i-Histrelin Ingcono Kune-Leuprolide?

Kokubili i-histrelin ne-leuprolide ziyimithi emihle yokucindezela amahomoni, kodwa ngalinye linobuhle obuhlukile. Inzuzo enkulu ye-Histrelin ukulula - i-implant eyodwa ihlala unyaka wonke, kuyilapho i-leuprolide ngokuvamile idinga imijovo njalo ezinyangeni ezimbalwa.

I-Leuprolide ingase ithandeke uma ukhathazekile ngokuba ne-implant ngaphansi kwesikhumba sakho noma uma ufuna ukuguquguquka ukuze umise ukwelashwa ngokushesha. Abanye abantu futhi bathola ukuthi ukusabela kwendawo yokujova akucasuli kangako kunemiphumela yendawo ye-implant.

Udokotela wakho uzokusiza ukuthi ulinganise lezi zinto ngokusekelwe endleleni yakho yokuphila, izidingo zezokwelapha, kanye nezintandokazi zakho. Yomibili le mithi isebenza kahle kakhulu uma isetshenziswa ngendlela efanele.

Imibuzo Evame Ukubuzwa Mayelana ne-Histrelin

Q1. Ingabe i-Histrelin Iphephile Ukusetshenziswa Isikhathi Eside?

I-Histrelin ngokuvamile iphephile ukusetshenziswa isikhathi eside uma iqashwe kahle ngumhlinzeki wakho wezempilo. Kodwa-ke, ukucindezelwa kwamahomoni isikhathi eside kungathinta ukuminyana kwamathambo, ngakho udokotela wakho cishe uzoncoma ukuhlolwa njalo kokuminyana kwamathambo futhi mhlawumbe izithasiselo ze-calcium ne-vitamin D.

Izinzuzo zokwelashwa ngokuvamile zidlula izingozi zezimo i-histrelin eziphatha zona. Udokotela wakho uzohlola njalo ukuthi ngabe ukuqhubeka nokwelashwa kuyadingeka futhi kuyazuzisa yini esimweni sakho esithile.

Umbuzo 2. Kufanele ngenzeni uma i-Histrelin Implant yami iphuma?

Uma i-implant yakho iphuma noma uqaphela ukuthi ayisahlali ngaphansi kwesikhumba sakho, xhumana nodokotela wakho ngokushesha. Lokhu akuvamile kodwa kungenzeka, ikakhulukazi emasontweni ambalwa okuqala ngemuva kokufakwa.

Ungazami ukuyifaka kabusha ngokwakho noma ungayinaki le ndaba. Udokotela wakho uzodinga ukuhlola le ndawo futhi cishe afake i-implant entsha ukuze aqinisekise ukwelashwa okuqhubekayo.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa ukufakwa kabusha kwe-Implant yami okuhleliwe?

Uma uliphuzile ukufakwa kabusha kwe-implant yakho okuhleliwe, xhumana nodokotela wakho ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Imiphumela yomuthi izoqala ukuncipha ngemuva kwezinyanga eziyi-12, okungavumela isimo sakho ukuthi sibuyele.

Udokotela wakho angase ancome ukuhlolwa kwegazi ukuze ahlolisise amazinga akho e-hormone futhi anqume isikhathi esingcono kakhulu sokufakwa kwakho okulandelayo. Ungalibali lolu hlelo, njengoba ukwelashwa okuqhubekayo kubalulekile ekuphatheni isimo sakho.

Umbuzo 4. Ngingayeka nini ukuthatha i-Histrelin?

Isinqumo sokuyeka ukwelashwa nge-histrelin sincike esimweni sakho esithile kanye nemigomo yokwelashwa. Kubantwana abanokuvuthwa ngaphambi kwesikhathi, ukwelashwa kuvame ukuyeka lapho befika eminyakeni efanele yokuthi ukuvuthwa kwemvelo kuqale kabusha.

Abantu abadala abanomdlavuza wendlala yesinye bangase badinge izikhathi zokwelashwa ezinde, ngezinye izikhathi unomphela. Udokotela wakho uzohlola njalo inqubekela phambili yakho futhi axoxe ngokuthi kungaba nini okufanelekile ukucabangela ukuyeka ukwelashwa.

Umbuzo 5. Ngingakwazi yini ukuzivocavoca ngokujwayelekile nge-Histrelin Implant?

Yebo, ngokuvamile ungenza umsebenzi wokuzivocavoca ngokujwayelekile nge-histrelin implant ngemuva kwesikhathi sokuqala sokuphola. Kufanele ugweme ukuzivocavoca ingalo okunzima ezinsukwini ezimbalwa zokuqala ngemuva kokufakwa kwe-implant ukuze uvumele ukuphola okufanele.

Lapho indawo yokufaka isiphile, i-implant akufanele iphazamise imisebenzi yakho ejwayelekile. Kodwa-ke, ungase uqaphele izinguquko emazingeni akho wamandla noma ukubekezelelana kokuzivocavoca ngenxa yezinguquko ze-hormone umuthi azidalayo.