Histrelin (indlela yokungenisa ngaphansi kwesikhumba)
Imikhiqizo etholakalayo
Supprelin LA, Vantas
Mayelana naleli khambi
I-Histrelin iyihomoni enziwe ngumuntu efana nehomoni yemvelo eyenziwa ebuchosheni. Leli lethu lisebenza ebuchosheni ukuze lwehlisa amazinga egazi ezihomoni zesondo, njenge-testosterone ne-estrogen. Ifakwa ngaphansi kwesikhumba sekhala lenja eliphezulu lapho ikhipha khona u-histrelin omncane emzimbeni nsuku zonke izinyanga eziyi-12. I-Histrelin (Vantas®) isetshenziswa ekwelapheni umdlavuza we-prostate osezingeni eliphezulu kubantu abadala. Kuzowehlisa amazinga e-testosterone, ihomoni yamadoda, egazini. I-Testosterone yenza uninzi lomdlavuza we-prostate ukukhula. I-Histrelin akuyona impilo yomdlavuza we-prostate, kodwa ingasiza ekuqedeni izimpawu. I-Histrelin (Supprelin® LA) isetshenziswa ekwelapheni i-central precocious puberty (CPP) kubantwana. I-CPP yisimo lapho ukuqala kwesondo kuqala ekuqaleni okungavamile. Lokhu ngokuvamile kusho ukuthi ukuqala kwesondo kwenzeka ngaphambi kweminyaka engu-8 kubantwana abesifazane nangaphambi kweminyaka engu-9 kubantwana abesilisa. Lolu lethu kufanele luphiwe kuphela yi noma ngaphansi kokunakekelwa okuqondile kwesiphephelo sezempilo esiqeqeshwe kahle. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma ukuthatha isinqumo sokuthatha imithi, kufanele kuqhathaniswe ubungozi bokuthatha imithi nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nokulimala okungavamile noma okubangelwa ukungezwani nale mithi noma eminye imithi. Tshela futhi ochwepheshe bezempilo uma unezinye izinhlobo zokungezwani, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenalo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Ifomu le-Vantas® le-histrelin akufanele lisetshenziswe kubantwana. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zezingane ezingakhawulela ukusetshenziswa kwe-Supprelin® LA kubantwana abaneminyaka emibili ubudala nangaphezulu. Noma kunjalo, ukusetshenziswa kubantwana abaneminyaka engaphansi kwemibili akukhuthazwa. Ukuphepha nokuphumelela akukaqiniswa. Ayikho imininingwane etholakalayo mayelana nobudlelwano bobukhulu nemiphumela ye-Supprelin® LA noma i-Vantas® kubantu abadala. Ayikho izifundo ezifanele kwabesifazane zokunquma ubungozi lwengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthola le mithi, kubalulekile kakhulu ukuthi ochwepheshe bezempilo bakwazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akukhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nanoma iyiphi imithi kungabangela ukusebenzisana. Xoxa nochwepheshe bezempilo bakho ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Udokotela noma omunye ochwepheshe bezempilo oqeqeshwe ngokucophelela uzokunika le miyeke. I-histrelin implant izofakwa phansi kwesikhumba endaweni yangaphakathi yengalo eliphezulu. Udokotela wakho uzophatha ingalo eliphezulu ngemithi yokunciphisa ubuhlungu (i-anesthetic) bese usika isiqeshana esincane ukuze afake i-implant. Lesi siqeshana sizovulwa ngezinsingo noma ngezigqoko ze-surgical. Ibhande lokucindezela lizofakwa phezu kwengalo bese lihlala khona amahora angu-24. Ungasusi izigqoko ze-surgical. Zivumele ziwe zodwa ngemva kwezinsuku ezimbalwa. Uma isiqeshana siye sancishwa, udokotela wakho uzozisusa izinsingo noma zizochithwa ngemva kwezinsuku ezimbalwa. Ngemva kokufakwa kwe-implant, kufanele ugcine ingalo ihlanzekile futhi yomile. Ungahambi noma ugeze amahora angu-24. Kufanele ugweme noma yiluphi ukuthwala okukhulu noma ukuzivocavoca okunzima ezinsukwini eziyisikhombisa zokuqala ngemva kokufakwa kwe-implant. I-implant izoshiywa khona unyaka (izinyanga eziyi-12) bese isuswa. Uma kudingeka, udokotela wakho uzofaka i-implant entsha ukuze aqhubeke nokuphatha unyaka olandelayo. Lolu lwemiyeke lungafika ne-Medication Guide nemiyalo yokuqondisa. Funda futhi ulandele le miyalo ngokucophelela. Buza udokotela wakho noma umthengisi wemithi uma unemibuzo. Sebenzisa kuphela uhlobo lolu lwemiyeke olulotshwe udokotela wakho. Ama-brand ahlukene angase angasebenzi ngendlela efanayo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.