Yini i-Hydrochlorothiazide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Hydrochlorothiazide iyiphilisi lamanzi elisiza umzimba wakho ukuthi uqede usawoti namanzi engeziwe ngomchamo. Lo muthi omnene kodwa osebenzayo ungoweqembu elibizwa ngokuthi ama-thiazide diuretics, futhi odokotela bavame ukuwuncoma ukuphatha umfutho wegazi ophezulu nokunciphisa ukuvuvukala okubangelwa ukwakheka kwamanzi.

Yini i-Hydrochlorothiazide?

I-Hydrochlorothiazide ngumuthi oqokiwe osebenza njenge-diuretic, okusho ukuthi isiza izinso zakho ukuthi zikhiphe uketshezi oluningi emzimbeni wakho. Ungase uzwe udokotela wakho ekubiza nge-HCTZ ngamafuphi, okwenza kube lula ukukusho nokukhumbula.

Lo muthi usetshenziswe ngokuphepha amashumi eminyaka ukwelapha izimo ezihlukahlukene ezihlobene nokugcinwa koketshezi nomfutho wegazi. Iza ngesimo samaphilisi futhi ivame ukuhlanganiswa neminye imithi yomfutho wegazi ukuze kunikeze imiphumela engcono.

Cabanga nge-hydrochlorothiazide njengomsizi omnene okhuthaza izinso zakho ukuthi zenze umsebenzi wazo ngempumelelo enkulu. Akuyona imithi enokhahlo, kodwa kunalokho ukwelashwa okuqhubekayo, okuthembekile okusebenza kancane kancane ngokuhamba kwesikhathi.

Isetshenziselwani i-Hydrochlorothiazide?

Odokotela ngokuyinhloko bancoma i-hydrochlorothiazide ukwelapha umfutho wegazi ophezulu nokugcinwa koketshezi. Lezi zimo ezimbili zivame ukuhamba ngasohlangothini, futhi lo muthi ubhekana nakho kokubili ngempumelelo.

Ngomfutho wegazi ophezulu, i-hydrochlorothiazide isiza ngokunciphisa inani loketshezi emithanjeni yakho yegazi. Uma kunoketshezi oluncane, inhliziyo yakho akudingeki isebenze kanzima ukuze ipompe igazi emzimbeni wakho, okunciphisa ngokwemvelo umfutho wegazi lakho.

Lo muthi futhi welapha i-edema, okuyisimo sokuvuvukala okubangelwa ukwakheka koketshezi oluningi ezicutshini zakho. Lokhu kuvuvukala kuvame ukwenzeka emilenzeni yakho, emaqakaleni, ezinyaweni, noma ezandleni futhi kungase kuvele ezimweni ezihlukahlukene okuhlanganisa ukuhluleka kwenhliziyo, isifo sesibindi, noma izinkinga zezinso.

Izikhathi ezithile odokotela banikeza i-hydrochlorothiazide ngezimo ezingavamile njenge-diabetes insipidus, isifo esingavamile esibangela ukuchama ngokweqile nokoma. Kulezi zimo, umuthi usiza izinso zakho ukuthi zigcine amanzi alinganiselwe.

Isebenza Kanjani I-Hydrochlorothiazide?

I-Hydrochlorothiazide isebenza ngokuvimba ukumuncwa kabusha kwe-sodium ne-chloride ezinso zakho. Lokhu kusho ukuthi izinso zakho zivumela usawoti namanzi amaningi ukuthi aphume emzimbeni wakho ngomchamo esikhundleni sokuwagcina emsingeni wegazi lakho.

Le nqubo yenzeka engxenyeni ethile yesinso sakho ebizwa ngokuthi i-distal convoluted tubule. Lapho i-hydrochlorothiazide ivimba ukumuncwa kabusha kwe-sodium lapha, idala umphumela we-domino oholela ekwandeni kokususwa kwamanzi futhi.

Lo muthi uthathwa njengomuthi oqinile ngokulinganisela phakathi kwama-diuretics. Umnene kune-loop diuretics efana ne-furosemide, kodwa usebenza kahle kune-potassium-sparing diuretics. Lokhu kuyenza ibe yindlela enhle ephakathi nendawo kubantu abaningi abadinga ukuphathwa kwamanzi.

Imiphumela ngokuvamile iqala kungakapheli amahora amabili ngemva kokuthatha umuthi futhi ingahlala kuze kube amahora angu-12. Cishe uzoqaphela ukwanda kokuchama ngalesi sikhathi, okuyindlela umuthi okufanele usebenze ngayo.

Kufanele Ngiyithathe Kanjani I-Hydrochlorothiazide?

Thatha i-hydrochlorothiazide ngendlela enembile njengoba udokotela wakho ekunikeza ngayo, ngokuvamile kanye ngosuku ekuseni. Ukuyithatha ekuseni kusiza ukuvimbela ukuvakashela endlini yangasese ebusuku okungaphazamisa ukulala kwakho.

Ungawuthatha lo muthi ngaphandle noma ngaphandle kokudla, kodwa ukuwuthatha nokudla kungasiza ukunciphisa isisu uma uhlangabezana nanoma yini. Uma ukhetha ukuyithatha nokudla, zama ukungaguquguquki ngale nqubo.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayichobozi, uhlafune, noma uyihlukanise ithebhulethi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo, njengoba lokhu kungathinta indlela umuthi osebenza ngayo.

Hlala uhle kahle ngenkathi uthatha i-hydrochlorothiazide, kodwa ungadluli. Phuza amanzi uma womile futhi ugcine ukuthatha uketshezi olujwayelekile ngaphandle uma udokotela wakho ekweluleka ngenye indlela.

Uma uthatha eminye imithi, yihlukanise ngesikhathi esifanele. Eminye imithi ingasebenzisana ne-hydrochlorothiazide, ngakho landela imiyalelo kadokotela wakho mayelana nesikhathi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Hydrochlorothiazide?

Ubude bokwelashwa nge-hydrochlorothiazide buxhomeke esimweni sakho esithile nokuthi usabela kahle kangakanani emuthini. Ngomfutho wegazi ophezulu, ungase udinge ukuyithatha isikhathi eside, mhlawumbe iminyaka noma impilo yakho yonke.

Uma uthatha i-hydrochlorothiazide ngenxa yokugcinwa koketshezi okuhlobene nesimo sesikhashana, isikhathi sakho sokwelashwa singaba sifushane. Udokotela wakho uzoqapha inqubekela phambili yakho futhi alungise ubude ngokuya ngentuthuko yakho.

Umfutho wegazi ophezulu ngokuvamile uyisimo esingamahlala-khona esidinga ukuphathwa okuqhubekayo. Noma ngabe uzizwa kahle, ukuyeka umuthi kungazelelwe kungabangela ukuthi umfutho wegazi wakho uphinde unyuke, okukubeka engozini yezinkinga.

Udokotela wakho uzohlola njalo umfutho wegazi lakho, ukusebenza kwezinso, kanye namazinga e-electrolyte ukuze anqume ukuthi kufanele uqhubeke yini nokuthatha umuthi. Lokhu kuhlolwa kusiza ukuqinisekisa ukuthi ukwelashwa kuhlala kuphephile futhi kusebenza kahle kuwe.

Ungalokothi uyeke ukuthatha i-hydrochlorothiazide ngaphandle kokubonisana nodokotela wakho kuqala. Bangase badinge ukunciphisa kancane kancane umthamo wakho noma bakushintshele komunye umuthi ukuze ugweme noma yiziphi izinkinga ezingaba khona.

Yiziphi Imiphumela Eceleni Ye-Hydrochlorothiazide?

Abantu abaningi bayayibekezelela kahle i-hydrochlorothiazide, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi imiphumela eminingi emibi ethambile iyathuthuka njengoba umzimba wakho ujwayela umuthi.

Nawa amanye imiphumela emibi evame kakhulu ongase uyithole:

• Ukuvuvukala kokuchama, ikakhulukazi emasontweni ambalwa okuqala
• Isiyezi noma ukukhathala lapho usukuma ngokushesha
• Ukuqaqamba kwekhanda
• Isicanucanu noma isisu esibuhlungu
• Ukukhathala noma ubuthakathaka
• Imisipha eqinile noma ubuthakathaka

Le miphumela emibi ejwayelekile ivame ukuba mncane futhi ivame ukwehla njengoba umzimba wakho ujwayela umuthi. Uma ziqhubeka noma zikuphazamisa kakhulu, khuluma nodokotela wakho mayelana nokulungiswa okungenzeka.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ubuthakathaka bemisipha obukhulu noma ukuqina
• Izimpawu zokuphelelwa amanzi emzimbeni njengokoma okukhulu noma umlomo owomile
• Ushintsho olungajwayelekile emoyeni noma esimweni sengqondo
• Isicanucanu esikhulu noma ukuhlanza

Imiphumela emibi engavamile kodwa ebucayi ihlanganisa izinkinga zezinso, ukungalingani okukhulu kwe-electrolyte, kanye nokusabela komzimba ngaphandle. Lezi zinkinga azivamile kodwa zidinga ukunakekelwa kwezokwelapha ngokushesha uma zenzeka.

Abanye abantu bangase babe nokuzwela ekukhanyeni, okusho ukwanda kokuzwela elangeni. Uma uqaphela ukuthi ushisa ilanga kalula, sebenzisa i-sunscreen nezingubo ezivikelayo uma uphuma ngaphandle.

Ubani Ongafanele Athathwe I-Hydrochlorothiazide?

Abantu abathile kufanele bagweme i-hydrochlorothiazide ngenxa yengozi eyengeziwe yezinkinga. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokunikeza lo muthi.

Akufanele uthathe i-hydrochlorothiazide uma unokungezwani nayo noma ezinye izidakamizwa ze-thiazide. Izimpawu zokungezwani komzimba zihlanganisa ukuqubuka, ukuluma, ukuvuvukala, isiyezi esikhulu, noma ukuhluleka ukuphefumula.

Abantu abanezifo ezinzima zezinso noma labo abangakwazi ukuchama akufanele bathathe lo muthi. Njengoba i-hydrochlorothiazide isebenza ngezinso, ukungasebenzi kahle kwezinso kungaholela ezinkingeni eziyingozi.

Labo abanezifo zesibindi ezinzima kufanele futhi bagweme lo muthi, njengoba ungenza ukusebenza kwesibindi kube kubi kakhulu. Udokotela wakho uzohlola impilo yesibindi sakho ngaphambi kokukuyalela i-hydrochlorothiazide.

Izimo ezithile zidinga ukuqapha okwengeziwe nokuqapha okuseduze:

• Isifo sikashukela, njengoba umuthi ungathinta amazinga kashukela egazini
• I-Gout, njengoba ingakhuphula amazinga e-uric acid
• I-Lupus, njengoba ingenza izimpawu zibe zimbi kakhulu
• Isifo senhliziyo esinzima
• Ukungalingani kwe-electrolyte
• Izinkinga zokuzwa

Abesifazane abakhulelwe ngokuvamile kufanele bagweme i-hydrochlorothiazide, ikakhulukazi ngesikhathi sesibili nesithathu. Umuthi ungangena ngaphakathi kwe-placenta futhi ungase ulimaze ingane esakhula.

Uma uncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. Inani elincane le-hydrochlorothiazide lingadlulela obisini lwebele, nakuba imiphumela emibi ezinganeni ezincelisayo ingavamile.

Amagama Omkhiqizo we-Hydrochlorothiazide

I-Hydrochlorothiazide itholakala ngaphansi kwamagama amaningana omkhiqizo, nakuba inguqulo ejwayelekile isetshenziswa kakhulu futhi isebenza ngendlela efanayo. Igama elivamile lomkhiqizo yi-Microzide, equkethe i-hydrochlorothiazide yodwa.

Uzovame ukuthola i-hydrochlorothiazide ihlanganiswe neminye imithi yokucindezela igazi emaphilisi amanye. Le mikhiqizo ehlanganisiwe inamagama ayo omkhiqizo futhi ingenza ukuthatha imithi eminingi kube lula.

Ezinye izinhlobo ezidumile zokuhlanganisa zihlanganisa i-Lisinopril/HCTZ (njenge-Zestoretic), i-Losartan/HCTZ (njenge-Hyzaar), ne-Valsartan/HCTZ (njenge-Diovan HCT). Lezi zinhlanganisela zisiza ukwelapha umfutho wegazi ophezulu ngempumelelo enkulu kunemithi eyodwa yodwa.

Inguqulo ejwayelekile ye-hydrochlorothiazide isebenza kahle njengezinhlobo zegama lomkhiqizo futhi ngokuvamile ibiza kancane. Ikhemisi lakho lingase lithathe indawo yenguqulo ejwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo.

Ezinye izindlela ze-Hydrochlorothiazide

Imithi eminingi ehlukile ingelapha izimo ezifanayo njenge-hydrochlorothiazide. Udokotela wakho angase acabange lezi zinketho uma ungakwazi ukubekezelela i-hydrochlorothiazide noma uma ingasebenzi kuwe.

Ezinye izidakamizwa ezinjenge-thiazide zihlanganisa i-chlorthalidone ne-indapamide. Le mithi isebenza ngendlela efanayo ne-hydrochlorothiazide kodwa ingase ibe nemiphumela ehlukile emzimbeni wakho noma ihlale isikhathi eside.

Ngenxa yomfutho wegazi ophezulu, ezinye izindlela ezingezona ezokwelapha ukuhlukanisa amanzi zihlanganisa ama-ACE inhibitors afana ne-lisinopril, ama-ARB afana ne-losartan, ama-calcium channel blockers afana ne-amlodipine, nama-beta-blockers afana ne-metoprolol. Le mithi yehlisa umfutho wegazi ngendlela ehlukile.

Uma udinga imiphumela eqinile yokuhlukanisa amanzi, udokotela wakho angase akubhalele ama-loop diuretics afana ne-furosemide. Lezi zinamandla kune-hydrochlorothiazide kodwa futhi zinomkhuba omkhulu wemiphumela emibi.

Kubantu abadinga ukugcina amazinga e-potassium, ama-potassium-sparing diuretics afana ne-spironolactone angase abe yizinketho ezingcono. Le mithi ithambile kodwa ingase ingasebenzi kahle ekususeni uketshezi.

Izindlela zemvelo ezinjengokushintsha ukudla, ukuzivocavoca njalo, ukuphatha isisindo, nokunciphisa ukucindezeleka kungasiza futhi ekuphatheni umfutho wegazi nokugcinwa koketshezi, nakuba kungase kunganele kubo bonke.

Ingabe i-Hydrochlorothiazide Ingcono Kune-Furosemide?

I-Hydrochlorothiazide ne-furosemide zombili ziyizidakamizwa ezihlukanisa amanzi, kodwa zisebenza ngendlela ehlukile futhi zisetshenziselwa izimo ezihlukene. Akukho noyedwa ongcono kunomunye ngoba bakhonza izinjongo ezihlukene.

I-Hydrochlorothiazide ithambile futhi isebenza kahle ekuphatheni isikhathi eside komfutho wegazi ophezulu nokugcinwa koketshezi oluncane kuya olulingene. Yiyona ekhethwayo ezimweni ezingapheli ngoba inemiphumela emibi embalwa futhi kulula ukuyibekezelela nsuku zonke.

I-Furosemide inamandla kakhulu futhi isebenza ngokushesha, okuyenza ibe ngcono ezimweni eziphuthumayo njengokuhluleka kwenhliziyo okukhulu noma uma udinga ukususwa kwamanzi ngokushesha. Kodwa-ke, kunzima emzimbeni wakho futhi kungadala ukungalingani okukhulu kwama-electrolyte.

Ukuze kulawulwe umfutho wegazi ophezulu, i-hydrochlorothiazide ngokuvamile iyona engcono ngoba inikeza imiphumela eqhubekayo, engaguquki ngaphandle kokunyuka nokwehla okukhulu okungadalwa yi-furosemide.

Uma unokwakheka kwamanzi okukhulu noma ukuhluleka kwenhliziyo, i-furosemide ingase idingeke ekuqaleni, kodwa odokotela bavame ukushintshela ku-hydrochlorothiazide ukuze bayigcine uma isimo esiphuthumayo sesilawulwa.

Udokotela wakho uzokhetha umuthi ofanele ngokuya ngesimo sakho esithile, ubukhulu bezimpawu, ukusebenza kwezinso, kanye nesimo sempilo yakho yonke. Ngesinye isikhathi bangase basebenzise ngisho nemithi yomibili ndawonye ngezinjongo ezihlukene.

Imibuzo Evame Ukubuzwa Nge-Hydrochlorothiazide

Ingabe i-Hydrochlorothiazide iphephile kubantu abanesifo sikashukela?

I-Hydrochlorothiazide ingasetshenziswa ngabantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Umuthi ungakhuphula kancane amazinga kashukela egazini, okusho ukuthi ungase udinge ukulungiswa emithini yakho yesifo sikashukela.

Udokotela wakho uzoqapha ushukela wakho wegazi eduze lapho uqala ukuthatha i-hydrochlorothiazide. Bangase bancomende ukuhlolwa kashukela wegazi kaningi noma ukulungiswa ohlelweni lwakho lokwelashwa isifo sikashukela.

Izinzuzo zokulawula umfutho wegazi ngokuvamile zidlula ingozi encane yezinguquko zikashukela egazini. Umfutho wegazi ophezulu uyingozi ikakhulukazi kubantu abanesifo sikashukela, ngakho-ke ukuwulapha ngempumelelo kubalulekile empilweni yakho yonke.

Uma uqaphela izinguquko ezingavamile emazingeni akho kashukela wegazi ngemuva kokuqala i-hydrochlorothiazide, xhumana nodokotela wakho ngokushesha. Bangakusiza ukuthi ulungise uhlelo lwakho lokwelashwa ukuze ulawule zombili izimo ngempumelelo.

Ngingenzani uma ngiphuthelwa ukusebenzisa i-Hydrochlorothiazide eningi kakhulu?

Uma ngabe uthatha i-hydrochlorothiazide eningi ngengozi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungabangela ukwehla okuyingozi kwengcindezi yegazi kanye nokungalingani okukhulu kwama-electrolyte.

Izimpawu zokweqisa zihlanganisa isiyezi esikhulu, ukuquleka, ubuthakathaka obukhulu, ukudideka, ukushaya kwenhliziyo okusheshayo, noma ubunzima bokuphefumula. Lezi zimpawu zidinga ukunakekelwa kwezokwelapha ngokushesha.

Ungazami ukuzelapha ngokweqisa ngokuthi uphuze amanzi engeziwe noma uthathe eminye imithi. Lokhu kungenza isimo sibe sibi kakhulu futhi kubambezele ukwelashwa okufanele kwezokwelapha.

Uma kungenzeka, letha ibhodlela lomuthi esibhedlela ukuze ochwepheshe bezokwelapha bazi kahle ukuthi uthatheni ini nokuthi kungakanani. Lolu lwazi lubasiza ukuthi banikeze ukwelashwa okufanele kakhulu.

Kufanele Ngenzeni Uma Ngedlula Umthamo We-Hydrochlorothiazide?

Uma udlula umthamo we-hydrochlorothiazide, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo owudlulile bese uqhubeka neshejuli yakho ejwayelekile.

Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owudlulile. Lokhu kungabangela ukuthi ingcindezi yakho yegazi yehle kakhulu noma kuholele ekulahlekelweni uketshezi okukhulu.

Uma uvame ukukhohlwa imithamo, zama ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule. Ukuthatha imithi ngokuqhubekayo kubalulekile ekulawuleni ingcindezi yegazi eqhubekayo.

Ukudlula umthamo ngezikhathi ezithile ngeke kubangele izinkinga ngokushesha, kodwa ukudlula imithamo njalo kungavumela ingcindezi yakho yegazi ukuthi ikhuphuke futhi kunciphise ukusebenza komuthi.

Ngingayeka Nini Ukuthatha I-Hydrochlorothiazide?

Kufanele uyeke kuphela ukuthatha i-hydrochlorothiazide ngaphansi kwesiqondiso sikadokotela wakho. Kubantu abaningi abanengcindezi yegazi ephezulu, lena imithi yesikhathi eside esiza ukuvimbela izinkinga ezinzima njengesifo senhliziyo nesitroko.

Uma uthatha i-hydrochlorothiazide ngenxa yokugcinwa kwamanzi okwesikhashana, udokotela wakho uzokutshela ukuthi kuphephile nini ukuyeka ngokusekelwe ekuthuthukisweni kwakho kanye nesimo esingaphansi.

Noma ngabe uzizwa kahle ngokuphelele, ungayeki imithi ngokwakho. Umfutho wegazi ophezulu akuvamile ukubangela izimpawu, ngakho ukuzizwa kahle akusho ukuthi awusadingi ukwelashwa.

Uma sekuyisikhathi sokuyeka, udokotela wakho cishe uzokwehlisa umthamo wakho kancane kancane kunokuthi uyeke kungazelelwe. Lokhu kusiza ekuvikeleni noma yimiphi imiphumela yokubuyela emuva noma izinguquko ezingazelelwe kumfutho wakho wegazi.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Hydrochlorothiazide?

Ungaphuza utshwala ngokulinganisela ngenkathi uthatha i-hydrochlorothiazide, kodwa qaphela kakhulu ngale nhlanganisela. Kokubili utshwala ne-hydrochlorothiazide kunganciphisa umfutho wakho wegazi futhi kubangele isiyezi.

Uma uphuza utshwala ngenkathi uthatha lo muthi, maningi amathuba okuthi uzwe ukukhathala, ikakhulukazi uma usukuma ngokushesha. Lokhu kwandisa ingozi yakho yokuwa noma ukuquleka.

Zilinganisele ekungeni ngaphezu kwesisodwa ngosuku uma ungumuntu wesifazane noma iziphuzo ezimbili ngosuku uma ungumuntu wesilisa. Lezi yizinkombandlela ezijwayelekile zokuphuza ngokulinganisela, futhi ukuhlala ngaphakathi kwale mikhawulo kunciphisa ingozi yakho yezinkinga.

Uma uqaphela ukwanda kwesiyezi, ubuthakathaka, noma eminye imiphumela emibi lapho uphuza utshwala, khuluma nodokotela wakho. Bangase bancomise ukugwema utshwala ngokuphelele noma ukulungisa umthamo wakho wemithi.