Yini i-Hydrocortisone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Hydrocortisone iyinguqulo yokwenziwa ye-cortisol, i-hormone umzimba wakho oyikhiqiza ngokwemvelo ezinqeni ze-adrenal. Uma ithathwa ngomlomo, isebenza njengomuthi onamandla wokulwa nokuvuvukala osiza ukunciphisa ukuvuvukala, ukuthulisa amasosha akho omzimba, nokufaka esikhundleni sama-hormone alahlekile lapho umzimba wakho ungenzi ngokwanele wona. Lo muthi ungowesigaba esibizwa ngokuthi ama-corticosteroids, ahlukile kuma-steroids abagijimi abangase bawasebenzise kabi.

Yini i-Hydrocortisone?

I-Hydrocortisone empeleni iyikhophi eyenziwe ngumuntu ye-cortisol, evame ukubizwa ngokuthi i-“hormone yokucindezeleka” yomzimba wakho. Izinqulu zakho ze-adrenal, ezihlala phezulu ezinso zakho, ngokuvamile zikhiqiza i-cortisol ukukusiza ukubhekana nokucindezeleka, ukulwa nokuvuvukala, nokugcina umfutho wegazi ophilile kanye namazinga kashukela egazini.

Uma uthatha i-hydrocortisone ngomlomo, unika umzimba wakho i-cortisol eyengeziwe noma ufaka esikhundleni salokho okungenziwa ngokwemvelo. Cabanga ngakho njengokuhlinzeka ngosizo lokusekela lapho ukukhiqizwa kwama-hormone omzimba wakho kungaphumeleli. Umuthi uza ngesimo samaphilisi futhi umuncwa ngohlelo lwakho lokugaya ukudla ungene egazini lakho.

Lo muthi ubhekwa njenge-corticosteroid enamandla aphakathi nendawo. Inobungane kunezinketho ezinamandla njenge-prednisone, okwenza ifaneleke ukusetshenziswa isikhathi eside ezimweni ezithile uma inqunywe ngendlela efanele ngumhlinzeki wakho wezempilo.

Isetshenziselwani i-Hydrocortisone?

I-Hydrocortisone iphatha izimo eziningana lapho umzimba wakho ungenzi i-cortisol eyanele noma udinga usizo olwengeziwe ekulweni nokuvuvukala. Isizathu esivamile odokotela abayinqumelayo yona ukwelashwa ngama-hormone kubantu abanokunganele kwe-adrenal.

Nawa amanye amazwi lapho i-hydrocortisone ingasiza ukubuyisela ibhalansi emzimbeni wakho:

• Isifo sika-Addison (ukungasebenzi kahle kwe-adrenal yokuqala) - uma amanyikwe akho e-adrenal engakhiqizi i-cortisol eyanele
• Ukungasebenzi kahle kwe-adrenal yesibili - uma i-pituitary gland yakho ingawathumeli kahle ama-adrenal akho
• I-Congenital adrenal hyperplasia - isimo se-genetic esithinta ukukhiqizwa kwamahomoni
• Ukuphendula okukhulu komzimba okungaphenduli kwezinye izindlela zokwelapha
• Izifo zamathumbu ezivuvukalayo njenge-ulcerative colitis noma isifo sikaCrohn
• Isifuba esibi kakhulu ngesikhathi sokugqashuka okukhulu
• I-Rheumatoid arthritis nezinye izimo zamalunga e-autoimmune
• Ezinye izimo zesikhumba njenge-eczema noma i-psoriasis engathi sína

Udkt wakho angase futhi anikeze i-hydrocortisone ezimweni ezingavamile njengokugqashuka kwe-lupus okukhulu noma izifo ezithile zegazi. Okubalulekile ukuthi isetshenziswa uma ukusabela komzimba kwakho okungokwemvelo okungavuvukali kudinga ukwesekwa okukhulu.

Isebenza Kanjani I-Hydrocortisone?

I-Hydrocortisone isebenza ngokulingisa lokho okwenziwa yi-cortisol yakho yemvelo nsuku zonke. Uma usuyigwinyile ithebhulethi, idlula ohlelweni lwakho lokugaya ukudla bese ingena egazini lakho, lapho ingafinyelela khona amaseli emzimbeni wakho wonke.

Umuthi ubopha kuma-receptors akhethekile ngaphakathi kwamaseli akho, ikakhulukazi amaseli omzimba, futhi ngokuyisisekelo uwatshela ukuthi azole. Lokhu kunciphisa ukuvuvukala, ukuvuvukala, kanye nokusabela komzimba okusebenzayo okungabangela ubuhlungu nokulimala kwesicubu. Kufana nokuba nomlamuli onekhono ongena ukuze athulise ingxoxo eshisa ngokweqile.

Kubantu abanokungasebenzi kahle kwe-adrenal, i-hydrocortisone ngokoqobo ithatha indawo ye-hormone elahlekile imizimba yabo engakwazi ukuyikhiqiza. Lokhu kusiza ukugcina umfutho wegazi ojwayelekile, amazinga kashukela egazini, kanye nekhono lomzimba lokuphendula ekucindezelekeni njengokugula noma ukulimala.

Njengoba kuyi-corticosteroid enamandla aphakathi nendawo, i-hydrocortisone ayinamandla njengemithi efana ne-prednisone noma i-prednisolone. Lokhu kwenza kuphephe ukusetshenziswa isikhathi eside kodwa futhi kusho ukuthi kungathatha isikhathi eside ukubona ukuthuthuka okukhulu ezimweni ezivuvukalayo.

Kufanele Ngiyithathe Kanjani I-Hydrocortisone?

Thatha i-hydrocortisone ngendlela eqondile udokotela wakho ayikushoyo, ngokuvamile ngokudla ukuvikela isisu sakho. Abantu abaningi bayithatha ekuseni ukuze balingise isigqi somzimba wakho esivamile se-cortisol, esiphezulu kakhulu uma uvuka.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ukuyithatha ngokudla noma ubisi kungasiza ekuvikeleni isisu esibuhlungu, okubaluleke kakhulu uma uthatha imithamo ephezulu. Uma unikezwe imithamo eminingi ngosuku, udokotela wakho cishe uzoncoma ukuthatha umthamo omkhulu ekuseni nemithamo emincane kamuva.

Zama ukuthatha umuthi wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga e-hormone aqhubekayo emzimbeni wakho. Uma uyithatha ngenxa yokungasebenzi kahle kwe-adrenal, ukuqina kubalulekile ngoba umzimba wakho uncike kulo mthombo wangaphandle we-cortisol ukuze usebenze kahle.

Ungalokothi uchoboze noma uhlafune amaphilisi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze njalo. Ezinye izindlela zokulungiselela zenzelwe ukukhipha umuthi kancane, futhi ukuwaphula kungakwenza uthole okuningi ngesikhathi esisodwa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Hydrocortisone?

Ubude bokwelashwa nge-hydrocortisone buqondile ngesimo sakho esithile nokuthi kungani uyithatha. Kubantu abanokungasebenzi kahle kwe-adrenal, lokhu ngokuvamile kuyimithi yokuphila konke esikhundleni se-hormone umzimba wakho ongenakuyenza.

Uma uthatha i-hydrocortisone ngezimo ezivuvukalayo njengokungezwani komzimba okukhulu noma i-arthritis, udokotela wakho cishe uzoyinika isikhathi esifushane ngangokunokwenzeka ukuze ulawule izimpawu zakho. Lokhu kungaba noma yikuphi kusukela ezinsukwini ezimbalwa kuya emavikini amaningana, kuye ngokuthi umzimba wakho usabela kanjani.

Ezimweni ze-autoimmune, ungase udinge i-hydrocortisone izinyanga noma iminyaka, kodwa udokotela wakho uzobuyekeza njalo ukuthi ungakwazi yini ukunciphisa umthamo noma ushintshe kwezinye izindlela zokwelapha. Umgomo uhlala ukusebenzisa umthamo ophumelelayo ophansi isikhathi esifushane esidingekayo.

Ungayeki ukuthatha i-hydrocortisone ngokuzumayo, ikakhulukazi uma ubuthatha isikhathi esingaphezu kwamasonto ambalwa. Umzimba wakho udinga isikhathi sokuzivumelanisa, futhi ukuyeka kungazelelwe kungabangela izimpawu ezinkulu zokuhoxisa noma i-adrenal crisis kubantu abanezinkinga ze-hormone.

Ziyini Imiphumela Eceleni ye-Hydrocortisone?

Njengayo yonke imithi, i-hydrocortisone ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Izindaba ezinhle ukuthi imiphumela eminingi emibi iyalawuleka futhi ingancipha njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi evame kakhulu ongase uyibone, ikakhulukazi emasontweni ambalwa okuqala kokwelashwa:

• Ukukhuphuka kwesifiso sokudla nokukhuluphala
• Ubunzima bokulala noma ukuzizwa ungaphumuli
• Ushintsho lwemizwa njengokuzizwa unemizwa eminingi noma uthukuthele
• Ukuphazamiseka kwesisu noma isilungulela
• Ukukhathazeka kwekhanda
• Isiyezi
• Ukujuluka okukhulu
• Ukugcinwa kwamanzi okuncane okubangela ukuvuvukala

Le miphumela evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Nokho, kunemiphumela emibi kakhulu edinga ukunakekelwa kwezokwelapha ngokushesha, nakuba ingavamile nge-hydrocortisone kune-corticosteroids enamandla.

Qaphela lezi zimpawu ezikhathazayo futhi uxhumane nodokotela wakho ngokushesha uma uzithola:

• Ushintsho olukhulu lwemizwa, ukucindezeleka, noma imicabango yokuzilimaza
• Izimpawu zokutheleleka njengomkhuhlane, ama-chills, noma umphimbo obuhlungu oqhubekayo
• Ukulimala okungavamile noma ukuphuma kwegazi
• Ubuhlungu obukhulu besisu noma izitulo ezimnyama, ezinama-tarry
• Ukukhuluphala ngokushesha noma ukuvuvukala okukhulu
• Ushintsho embonweni noma ubuhlungu bamehlo
• Ubuthakathaka bemisipha noma ubuhlungu bamathambo
• Ukushaya kwenhliziyo okungajwayelekile

Ukusetshenziswa kwesikhathi eside kwe-hydrocortisone, ikakhulukazi ngemithamo ephezulu, kungaholela ezinkingeni ezingathi sína ezinjengokuncipha kwamathambo, ukwanda kwengozi yokutheleleka, noma izinkinga zikashukela egazini. Udokotela wakho uzokuhlola njalo ukuze abambe noma yiziphi izinkinga zisasekuqaleni.

Ubani Ongafanele Athathwe I-Hydrocortisone?

Ngenkathi i-hydrocortisone ivikelekile ngokuvamile kubantu abaningi uma isetshenziswa ngendlela efanele, abantu abathile badinga ukuyigwema noma bayisebenzise ngokuqapha okukhulu. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi.

Akufanele uthathe i-hydrocortisone uma wazi ukuthi unokungezwani komzimba ne-hydrocortisone noma yiziphi izithako eziqukethwe emaphilisi. Ngaphezu kwalokho, abantu abanezifo ezithile ezisebenzayo, ikakhulukazi izifo zama-fungal, kufanele bagweme lo muthi ngoba ungasicindezela amasosha omzimba futhi wenze izifo zibe zimbi kakhulu.

Izimo eziningana zidinga ukucatshangelwa okukhethekile nokuqapha okuseduze uma udinga ukwelashwa nge-hydrocortisone:

• Isifo sikashukela - i-hydrocortisone ingakhuphula amazinga kashukela egazini
• Umfutho wegazi ophezulu noma izinkinga zenhliziyo
• Izilonda zesisu noma umlando wokopha kwesisu
• I-Osteoporosis noma amathambo abuthakathaka
• I-Glaucoma noma ama-cataracts
• Isifo sesibindi noma sezinso
• Izimo zempilo yengqondo njengokucindezeleka noma ukukhathazeka
• Izifo ze-thyroid

Uma ukhulelwe noma uncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. I-Hydrocortisone ingawela i-placenta futhi idlulele obisini lwebele, kodwa ngezinye izikhathi izinzuzo zidlula izingozi, ikakhulukazi ezimweni ezinjengokungasebenzi kahle kwe-adrenal.

Abantu abaneminyaka engaphezu kwengama-65 bangase bazwe imiphumela emibi kakhulu futhi bangase badinge imithamo ephansi noma ukuqapha okuningi. Udokotela wakho uzolungisa uhlelo lwakho lokwelashwa ngokusekelwe eminyakeni yakho nempilo yonke.

Amagama Omkhiqizo we-Hydrocortisone

I-Hydrocortisone itholakala ngaphansi kwamagama amaningi emikhiqizo, nakuba inguqulo ejwayelekile isebenza kahle futhi ivame ukuba ngentengo ephansi. Igama lomkhiqizo elivamile le-hydrocortisone yomlomo yi-Cortef, ethenjwe odokotela amashumi eminyaka.

Amanye amagama emikhiqizo ongahlangana nawo afaka i-Hydrocortone, nakuba lokhu kungatholakali kakhulu manje. Amanye amakhemisi okuhlanganisa nawo angakha amafomula enziwe ngokwezifiso e-hydrocortisone uma udinga amandla athile noma unezinto ezingezwani nazo ezingasebenzi.

Noma ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile, isithako esisebenzayo siyafana. I-Hydrocortisone ejwayelekile isebenza kahle futhi ihlangabezana namazinga okuphepha afanayo nezinguqulo zegama lomkhiqizo. Umuthi wakho womuthi angakusiza ukuthi uqonde noma yiziphi izinto ezingasebenzi uma unezinto ezithile ozwelayo.

Ezinye izindlela ze-Hydrocortisone

Ezinye izindlela ze-hydrocortisone ziyatholakala, kuye ngesimo sakho esithile kanye nemigomo yokwelashwa. Ukuze kuthathwe indawo yamahomoni ekunganele kwe-adrenal, i-hydrocortisone ivame ukukhethwa ngoba ilingisa kakhulu isigqi somzimba wakho semvelo se-cortisol.

Nokho, ezinye izidakamizwa ze-corticosteroid zingaba izinketho zezimo ezivuthayo. I-Prednisone ne-prednisolone yimithi eqeda ukuvuvukala enamandla esebenza kahle ekwelashweni kwesikhashana kokuvuvukala okukhulu, kodwa akulungile ukusetshenziswa kwesikhathi eside ngenxa yemiphumela emibi ebaluleke kakhulu.

Kubantu abanokunganele kwe-adrenal, ezinye izindlela zingafaka:

• I-Cortisone acetate - inketho endala umzimba wakho oyiguqula ube yi-hydrocortisone
• I-Prednisolone - ngezinye izikhathi isetshenziswa ezinganeni noma kubantu abangakwazi ukumunca i-hydrocortisone kahle
• I-Dexamethasone - ngezinye izikhathi isetshenziselwa izimo ezithile, nakuba inamandla kakhulu

Ezinye izindlela ezingezona ze-steroid ziyatholakala kwezinye izimo ezivuvukalayo, njengemithi eguqula izifo ze-antirheumatic (DMARDs) ye-rheumatoid arthritis noma i-biologics ye-inflammatory bowel disease. Lezi zisebenza ngendlela ehlukile kune-corticosteroids futhi zingaba izinketho ezingcono zesikhathi eside zezinye izimo.

Ingabe i-Hydrocortisone ingcono kune-Prednisone?

I-Hydrocortisone ne-prednisone zisebenzela izinhloso ezihlukene, ngakho-ke akukho okukodwa okungcono kunomunye. Ukukhetha kuncike esimweni sakho esithile, imigomo yokwelashwa, nokuthi udinga ukuthatha imithi isikhathi esingakanani.

I-Hydrocortisone inobungane futhi ifana kakhulu ne-cortisol yakho yemvelo yomzimba, okuyenza ibe yindlela ekhethwayo yokwelashwa kwe-hormone esikhathini sokungasebenzi kahle kwe-adrenal. Futhi ingcono ekusetshenzisweni kwesikhathi eside ngoba ibangela imiphumela emibi embalwa kakhulu kunama-corticosteroids aqinile.

I-Prednisone iqina cishe izikhathi ezine kune-hydrocortisone, okuyenza isebenze kahle ekulawuleni ngokushesha ukuvuvukala okukhulu. Kodwa-ke, lobu bunzima buza nengozi enkulu yemiphumela emibi, ikakhulukazi ekusetshenzisweni kwesikhathi eside. I-Prednisone ivame ukusetshenziselwa ukwelashwa kwesikhashana kwezikhathi zokuvuvukala.

Kubantu abanokungasebenzi kahle kwe-adrenal, i-hydrocortisone cishe iyona engcono kakhulu ngoba inikeza ukushintshwa kwe-hormone okuzinzile, okungokwemvelo. Ezimweni ezivuvukalayo, udokotela wakho angase aqale nge-prednisone ukuze athole ukukhululeka okusheshayo, bese eshintshela ku-hydrocortisone noma ezinye izindlela zokwelapha ukuze kulawulwe isikhathi eside.

Imibuzo Evame Ukubuzwa Mayelana ne-Hydrocortisone

Ingabe i-Hydrocortisone iphephile kubantu abanesifo sikashukela?

I-Hydrocortisone ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela nokulungiswa okungenzeka emithini yakho yesifo sikashukela. Ama-corticosteroids afana ne-hydrocortisone angakhuphula amazinga kashukela egazini ngokwenza umzimba wakho umelane kakhulu ne-insulin.

Uma unesifo sikashukela futhi udinga i-hydrocortisone, udokotela wakho cishe uzoncoma ukuhlola ushukela wakho wegazi kaningi, ikakhulukazi uma uqala umuthi noma ushintsha imithamo. Ungase udinge ukulungisa i-insulin yakho noma eminye imithi yesifo sikashukela ukuze ugcine ukulawulwa okuhle kukashukela wegazi.

Izindaba ezinhle ukuthi umphumela we-hydrocortisone kushukela wegazi ngokuvamile awunamandla kangako kunama-corticosteroids aqinile afana ne-prednisone. Abantu abaningi abanesifo sikashukela bangayithatha i-hydrocortisone ngempumelelo ngokulandela kahle nokulungiswa kwemithi.

Kufanele ngenzeni uma ngisebenzisa i-Hydrocortisone eningi ngengozi?

Uma ngengozi uthatha i-hydrocortisone eningi, ungesabi, kodwa kuyithathe ngokungathí sina. Xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ikakhulukazi uma uthathe okuningi kakhulu kunokunqunywe noma uma uhlangabezana nezimpawu ezikhathazayo.

Izimpawu zokweqisa kwe-hydrocortisone zingabandakanya isicanucanu esibi, ukuhlanza, isiyezi, ikhanda elibuhlungu, ubuthakathaka bemisipha, noma ukudideka. Ezimweni ezinzima, ungase uhlangabezane nezinguquko kumgqigqo wenhliziyo noma umfutho wegazi. Lezi zimpawu zidinga ukunakekelwa kwezokwelapha ngokushesha.

Uma sekudlule ihora elilodwa kusukela ngesikhathi uthathe umthamo owengeziwe futhi awuzizwa zimpawu, udokotela wakho angase ancome ukuphuza amanzi amaningi futhi uzihlole ngokucophelela. Ungalokothi uzame "ukulinganisa" ukweqisa ngokweqa imithamo yesikhathi esizayo ngaphandle kwesiqondiso sezokwelapha.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Hydrocortisone?

Uma uphuthelwa umthamo we-hydrocortisone, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise eyodwa ephuthelwe.

Kulabo abathatha i-hydrocortisone ngenxa yokungasebenzi kahle kwamadlala e-adrenal, ukweqa imithamo kungaba yingozi enkulu ngoba umzimba wakho uthembele kulolu hlobo lwangaphandle lwe-cortisol. Uma uvame ukukhohlwa imithamo, cabangela ukusetha ama-alamu ocingo noma ukusebenzisa umhleli wamaphilisi ukukusiza ukhumbule.

Uma weqa imithamo eminingi noma uzizwa ungazizwa kahle ngemva kokweqa imithamo, xhumana nodokotela wakho ngokushesha. Abantu abanokungasebenzi kahle kwamadlala e-adrenal bangathuthukisa izimpawu eziyingozi uma behamba isikhathi eside ngaphandle kwemithi yabo, ikakhulukazi ngezikhathi zokucindezeleka noma ukugula.

Ngingayeka nini Ukuthatha i-Hydrocortisone?

Ungayeki ukuthatha i-hydrocortisone ngokuzumayo ngaphandle kwesiqondiso sikadokotela wakho, ikakhulukazi uma ubuthatha isikhathi esingaphezu kwamasonto ambalwa. Umzimba wakho udinga isikhathi sokuzivumelanisa lapho uyeka ama-corticosteroids, futhi ukuyeka kungazelelwe kungabangela izimpawu ezinkulu zokuhoxisa.

Kubantu abanokungasebenzi kahle kwamadlala e-adrenal, i-hydrocortisone ngokuvamile iyimithi yokuphila konke. Umzimba wakho awukwazi ukukhiqiza i-cortisol eyanele ngokwemvelo, ngakho ukuyeka imithi kungaholela esimweni esisongela impilo esibizwa ngokuthi i-adrenal crisis.

Uma uthatha i-hydrocortisone ngezimo zokuvuvukala, udokotela wakho uzokwenza isimiso sokunciphisa kancane kancane umthamo wakho ezinsukwini noma emasontweni. Lokhu kuvumela ukukhiqizwa kwe-cortisol yemvelo yomzimba wakho ukuthi kuqale kancane kancane. Isimiso sokunciphisa sincike ekutheni ubuthatha isikhathi esingakanani imithi nokuthi umzimba wakho usabela kanjani.

Ngingayithatha i-Hydrocortisone Ngesikhathi Sokukhulelwa?

I-Hydrocortisone ingasetshenziswa ngesikhathi sokukhulelwa lapho izinzuzo zidlula izingozi, kodwa lesi sinqumo sidinga ukucatshangelwa ngokucophelela nomhlinzeki wakho wezempilo. Imithi ingawela i-placenta futhi ingase ithinte ingane yakho esakhula.

Kwabesifazane abanezinkinga ze-adrenal, ukuqhubeka nokuthatha i-hydrocortisone ngesikhathi sokukhulelwa kuvamile ukuthi kubalulekile ngoba ukungasebenzi kahle kwe-adrenal okungalashwa kubeka ubungozi obukhulu kumama nomntwana. Udokotela wakho angase alungise umthamo wakho ngesikhathi sokukhulelwa nokubeletha ukuze kubhekelwe ukwanda kwengcindezi emzimbeni wakho.

Uma uthatha i-hydrocortisone ngezimo zokuvuvukala futhi ukhulelwe, xoxa ngezindlela ezingezinye nodokotela wakho. Ngezinye izikhathi ezinye izindlela zokwelapha zingase ziphephe ngesikhathi sokukhulelwa, noma udokotela wakho angase ancome umthamo ophansi osebenzayo isikhathi esifushane ngangokunokwenzeka.