Yini i-Hydroxocobalamin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Hydroxocobalamin iyindlela kavithamini B12 odokotela abayinikeza nge-IV lapho umzimba wakho uyidinga ngokushesha le vithamini ebalulekile. Cabanga ngayo njengokwelashwa okunamandla, okusebenza ngokushesha okudlula ngqo uhlelo lwakho lokugaya ukudla, okuletha uvithamini B12 ngqo emgudwini wakho wegazi lapho ungaqala khona ukusebenza ngokushesha.

Lo muthi ubaluleke kakhulu ngoba uvithamini B12 ufeza indima ebalulekile ekugcineni imizwa yakho iphilile, ekwenzeni amaseli abomvu egazi, nasekusizeni umzimba wakho ukuthi ukhiqize i-DNA. Uma ungakwazi ukumunca i-B12 eyanele ekudleni noma ekudleni okwengeziwe, ukujova kwe-hydroxocobalamin kuba yisixazululo esingavimbela izinkinga ezinzima.

Isetshenziselwani i-Hydroxocobalamin?

Ukujova kwe-Hydroxocobalamin kulapha ukwelapha ukuntuleka okukhulu kavithamini B12, ikakhulukazi uma umzimba wakho ungenakuyimunca le vithamini ngokugaya okujwayelekile. Lokhu kuvame ukwenzeka ngesimo esibizwa ngokuthi i-pernicious anemia, lapho isisu sakho singakhiqizi amaprotheni anele adingekayo ukuze kumuncwe i-B12 ekudleni.

Udokotela wakho angase futhi ancome lokhu kwelashwa uma unezifo ezithile zokugaya ukudla njenge-Crohn's disease, i-celiac disease, noma uma uhlinzwe esiswini okuthinta ukumuncwa kwe-B12. Abanye abantu bathuthukisa ukuntuleka kwe-B12 ngemva kokusebenzisa imithi ethile isikhathi eside noma ngenxa yokudla okuyimifino okuqinile ngaphandle kokwengezwa okufanele.

Ezimweni eziphuthumayo, i-hydroxocobalamin isebenza njengokwelapha ubuthi be-cyanide, nakuba lokhu kusetshenziswa kudinga ukunakekelwa kwezokwelapha ngokushesha esibhedlela. Umuthi usebenza ngokubopha kuma-molecule e-cyanide nokusiza umzimba wakho ukuthi uwaqede ngokuphepha.

Isebenza Kanjani i-Hydroxocobalamin?

I-Hydroxocobalamin isebenza ngokugcwalisa izitolo zomzimba wakho zikavithamini B12 ezingeni leselula. Uma isijovwe, ihamba ngomgudu wegazi lakho bese iguqulelwa ezinhlotsheni ezisebenzayo ze-B12 ezidingwa umzimba wakho - i-methylcobalamin ne-adenosylcobalamin.

Lokhu kubhekwa njengokwelashwa okuqinile nokusebenzayo kakhulu ngoba kuletha i-vitamin B12 ngqo lapho umzimba wakho uyidinga khona kakhulu. Ngokungafani nezithasiselo zomlomo okufanele zidlule ohlelweni lwakho lokugaya ukudla, uhlobo lwe-IV luqinisekisa ukumuncwa okucishe kube ngu-100%, okwenza kube namandla ikakhulukazi kubantu abanezinkinga ezinkulu.

Umuthi ugcinwa esibindini sakho nakwezinye izicubu, udala indawo yokugcina umzimba wakho ongathatha kuyo amasonto amaningana noma izinyanga. Lolu hlelo lokugcina lisho ukuthi ngeke udinge imijovo ejwayelekile uma amazinga akho esebuyiselwe.

Kufanele Ngiyithathe Kanjani I-Hydroxocobalamin?

I-Hydroxocobalamin inikezwa kuphela ochwepheshe bezempilo ngomugqa we-IV endaweni yezokwelapha. Awukwazi ukuthatha lo muthi ekhaya - idinga ukugadwa kahle kwezokwelapha nemishini enezinambuzane.

Ngaphambi kokwelashwa kwakho, awudingi ukuzila ukudla noma ukugwema noma yikuphi ukudla okuthile. Eqinisweni, ukudla ukudla okulula ngaphambi kwesikhathi kungasiza ekuvimbeleni noma yikuphi ukugajuka okungenzeka ngenxa yokwelashwa. Hlala unamanzi kahle ngokuphuza amanzi amaningi ngaphambi nangemva kokuqokwa kwakho.

Umujovo ngokwawo uvame ukuthatha imizuzu engaba ngu-15-30, ngesikhathi ozohlala ngaso ngokunethezeka ngenkathi umuthi ungena kancane emithanjeni yakho yegazi. Abantu abaningi bathola ukuthi inqubo iyabekezeleleka, ifana nokuthola eminye imithi ye-IV noma uketshezi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Hydroxocobalamin?

Ubude bokwelashwa kwe-hydroxocobalamin buqondene ngokuphelele nokuthi yini ebangela ukuntuleka kwakho kwe-B12 nokuthi umzimba wakho usabela kanjani. Nge-pernicious anemia noma izinkinga zokumuncwa unomphela, cishe uzodinga imijovo impilo yakho yonke, ngokuvamile njalo ezinyangeni ezimbalwa uma amazinga akho esezinzile.

Uma ukuntuleka kwakho kuvele ngenxa yezinto zesikhashana ezinjengemiphumela emibi yemithi noma izinkinga zokudla, ungase udinge ukwelashwa izinyanga ezimbalwa kuphela. Udokotela wakho uzoqapha amazinga akho e-B12 ngokusebenzisa ukuhlolwa kwegazi ukuze anqume isimiso esifanele sakho.

Ekuqaleni, ungase uthole imijovo kaningi - mhlawumbe masonto onke noma njalo ngemva kwamasonto amabili - kuze kube yilapho izitolo zomzimba wakho zigcwaliswa. Uma amazinga akho ejwayelekile, imvamisa ivamise ukwehla ibe imithamo yokugcinwa yanyanga zonke noma ngekota ngonyaka.

Yiziphi Imiphumela Eceleni ye-Hydroxocobalamin?

Abantu abaningi bayayibekezelela kahle kakhulu imijovo ye-hydroxocobalamin, nemiphumela emibi ngokuvamile iba mnene futhi yesikhashana. Izimpendulo ezivamile kakhulu zenzeka endaweni yokujova noma ngemva nje kokwelashwa.

Nansi imiphumela emibi ongase uyithole, ukhumbula ukuthi abantu abaningi abanayo imiphumela emibi nakancane:

• Ubuhlungu obuncane, ububomvu, noma ukuvuvukala endaweni ye-IV
• Ukubomvu kwesikhashana noma ukufudumala ebusweni nasentanyeni yakho
• Isicanucanu esincane noma ukungakhululeki kwesisu
• Ikhanda elivame ukuxazululwa emahoreni ambalwa
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Ukuqubuka kwesikhumba kwesikhashana noma ukuluma

Le miphumela ejwayelekile ivamise ukushabalala emahoreni ambalwa futhi ayidingi ukwelashwa okukhethekile ngaphandle kokuphumula nokuthatha amanzi amaningi.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha, nakuba ingavamile kakhulu:

• Ukungezwani komzimba okukhulu nokuphefumula okunzima noma ukuvuvukala kobuso nomphimbo
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile
• Isiyezi esikhulu noma ukuquleka
• Ubuthakathaka bemisipha obungajwayelekile noma ukuba ndikindiki
• Ukuphalaza okuqhubekayo noma ubuhlungu obukhulu besisu

Uma uhlangabezana nanoma yiziphi lezi zimpawu ezinzima, funa usizo lwezokwelapha ngokushesha. Ithimba lakho lokunakekelwa kwezempilo lilungele kahle ukubhekana nanoma yiziphi izinkinga ezingase zivele.

Ubani Ongafanele Athole I-Hydroxocobalamin?

I-Hydroxocobalamin iphephile ngokuphawulekayo kubantu abaningi, kodwa izimo ezithile zidinga ukuqapha okwengeziwe noma ukwelashwa okuhlukile. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuncoma lo muthi.

Kufanele wazise umhlinzeki wakho wezempilo uma unezinye zalezi zimo:

• Ukungezwani okwaziwayo ne-vitamin B12 noma i-cobalt
• Isifo sikaLeber (isimo samehlo esingavamile esizuzwe ngomlando womndeni)
• Isifo sezinso esibi kakhulu
• Ukutheleleka okusebenzayo noma umkhuhlane
• Umlando wokungezwani okukhulu nezinto ezijovwayo

Ukukhulelwa nokuncelisa ngokuvamile akuyona imigoqo ekwelashweni, njengoba i-vitamin B12 ibalulekile kokubili kumama nomntwana. Nokho, udokotela wakho uzolungisa umthamo nokuqapha njengoba kudingeka ngalezi zikhathi.

Uma usebenzisa imithi ethile efana ne-chloramphenicol noma i-metformin isikhathi eside, udokotela wakho angase adinge ukulungisa uhlelo lwakho lokwelashwa, njengoba lezi zingathinta ukumuncwa kwe-B12 noma ukusebenza kahle.

Amagama Omkhiqizo we-Hydroxocobalamin

Ukujova kwe-Hydroxocobalamin kutholakala ngaphansi kwamagama amaningi omkhiqizo, i-Cyanokit iyona eyaziwa kakhulu ekwelashweni kokubulawa yi-cyanide. Ngokuntuleka kwe-vitamin B12, kuvame ukutholakala njengomuthi ojwayelekile obizwa nje ngokuthi "i-hydroxocobalamin injection."

Ikhemisi lakho noma indawo yokunakekelwa kwezempilo ingase isebenzise amagama omkhiqizo ahlukene noma izinguqulo ezijwayelekile, kodwa isithako esisebenzayo nokusebenza kahle kuhlala kufana. Ungakhathazeki uma ukupakishwa kubukeka kuhluke kulokho obukulindele - usokhemisi wakho angaqinisekisa ukuthi uthola umuthi olungile.

Ezinye Izindlela ze-Hydroxocobalamin

Ezinye izindlela eziningana ziyatholakala zokwelapha ukuntuleka kwe-vitamin B12, nakuba ukukhetha okungcono kuncike esimweni sakho esithile nokuthi umzimba wakho uyimunca kahle kangakanani i-vitamin.

Kubantu abangakwazi ukumunca i-B12 ethile ngokugaya ukudla, izithasiselo zomlomo ezinomthamo ophezulu noma amaphilisi angaphansi kolimi (ngaphansi kolimi) angasebenza. Lezi zinketho zikulungele ukusetshenziswa ekhaya kodwa zidinga ukulinganiswa kwansuku zonke.

Ukujova kwe-Cyanocobalamin kumelela enye inketho ejovwayo, nakuba odokotela abaningi bekhetha i-hydroxocobalamin ngoba ihlala esimisweni sakho isikhathi eside futhi ingasebenza kahle ezinhlotsheni ezithile zokuntuleka.

Izinhlobo ze-B12 zokufutha ngamakhala zinikeza indawo emaphakathi phakathi kwezithasiselo zomlomo kanye nemijovo, zinikeza ukumuncwa okungcono kunezithasiselo ngenkathi zingahlaseli kangako kunokwelashwa nge-IV.

Ingabe i-Hydroxocobalamin ingcono kune-Cyanocobalamin?

I-Hydroxocobalamin ivame ukubhekwa njengephakeme kune-cyanocobalamin ngezizathu eziningana ezibalulekile. Ihlala emzimbeni wakho isikhathi eside, okusho ukuthi udinga imijovo embalwa ukuze ugcine amazinga e-B12 enempilo.

I-Hydroxocobalamin iphinde iguquke ngempumelelo ibe izinhlobo ezisebenzayo ze-B12 ezisetshenziswa ngempela umzimba wakho. Lokhu kuyenza ibe yinzuzo ikakhulukazi kubantu abanezinkinga ezinzima noma izinkinga zokumuncwa.

Kubantu ababhemayo noma abaye bachayeka emathini, i-hydroxocobalamin inikeza enye inzuzo ngoba ingasiza ekunciphiseni izinto eziyingozi njenge-cyanide. I-Cyanocobalamin, ngokumangalisayo, iqukethe inani elincane le-cyanide, okwenza i-hydroxocobalamin ibe yindlela ephephe kakhulu yabantu abathile.

Noma kunjalo, i-cyanocobalamin isalokhu iyindlela yokwelapha esebenzayo ebiza kancane futhi isetshenziswe ngokuphepha amashumi eminyaka. Udokotela wakho uzokusiza ukhethe inketho engcono kakhulu ngokusekelwe ezidingweni zakho kanye nezimo zakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Hydroxocobalamin

Ingabe i-Hydroxocobalamin iphephile ezigulini zenhliziyo?

I-Hydroxocobalamin ngokuvamile iphephile kubantu abanezifo zenhliziyo futhi ingase ngempela isize ukuthuthukisa impilo yenhliziyo nemithambo yegazi ngokulungisa ukuntula kwe-B12. Amazinga aphansi e-B12 angaholela ekunyukeni kwe-homocysteine, okwandisa ingozi yesifo senhliziyo.

Noma kunjalo, yazisa udokotela wakho wenhliziyo mayelana nokwelashwa kwakho kwe-B12, njengoba bengase bakufune ukukuqapha eduze ngesikhathi sokwelashwa kokuqala. Umuthi awavamisile ukuthinta isigqi senhliziyo noma umfutho wegazi, kodwa ithimba lakho lezempilo lizobheka noma yiziphi izinguquko.

Ngingenzani uma ngithola i-Hydroxocobalamin eningi ngengozi?

Ukweqisa kwe-Vitamin B12 akuvamile kakhulu ngoba umzimba wakho ukhipha ngempumelelo amanani amaningi ngomchamo. Ngisho nemithamo ephezulu ivame ukubekezelelwa kahle ngaphandle kwemiphumela emibi.

Uma ukhathazekile ngokuthola okuningi, xhumana nomhlinzeki wakho wezempilo ukuze uqinisekiswe. Bangakwazi ukuqapha amazinga akho futhi balungise imithamo yesikhathi esizayo uma kudingeka. Abantu abaningi ababi nazinkinga ezivela emithamini ephezulu kunaleyo ehlosiwe.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Hydroxocobalamin?

Xhumana nomhlinzeki wakho wezempilo ngokushesha lapho uqaphela ukuthi uphuthelwe umjovo wakho ohleliwe. Ungazami ukukwenza ngokuthatha imithamo eyengeziwe - udokotela wakho uzokusiza ukuthi ubuyele emgwaqeni ngokuphepha.

Ukuphuthelwa umthamo owodwa akuvamile ukubangela izinkinga ngokushesha ngoba umzimba wakho ugcina i-B12 amasonto amaningana noma izinyanga. Kodwa-ke, ukuhlala uqhubeka neshejuli yakho yokwelashwa kusiza ukugcina amazinga aphezulu futhi kuvimbela izimpawu zokuntuleka ukuthi zingabuyi.

Ngingayeka nini ukuthatha i-Hydroxocobalamin?

Ungalokothi uyeke ukwelashwa nge-hydroxocobalamin ngaphandle kokuxoxa ngakho nodokotela wakho kuqala. Uma une-pernicious anemia noma izinkinga zokumunca unomphela, cishe uzodinga ukwelashwa impilo yakho yonke ukuze uvimbele izinkinga ezinzima.

Ukuntuleka kwesikhashana, udokotela wakho uzonquma ukuthi kuphephile nini ukuyeka ngokuya ngamazinga akho e-B12 nesimo esingaphansi. Bangase bakushintshele ekuthathweni kwemithi yomlomo noma bamane baqaphe amazinga akho njalo ukuze baqinisekise ukuthi ukuntuleka akubuyi.

Ngingashayela ngemva kokuthola i-Hydroxocobalamin?

Abantu abaningi bangashayela ngokuphepha ngemva kokuthola i-hydroxocobalamin, kodwa linda okungenani imizuzu engama-30 ngemva kokwelashwa ukuze uqinisekise ukuthi awuzizwa unesiyezi noma eminye imiphumela emibi. Uma uzizwa unesiyezi noma ungazizwa kahle, lungiselela omunye umuntu ukuthi akuqhubele ekhaya.

Umuthi ngokwawo awuphazamisi ikhono lakho lokushayela, kodwa abanye abantu bazizwa bekhathele okwesikhashana noma benesiyezi ngemva kokwelashwa nge-IV. Lalela umzimba wakho futhi ubeke phambili ukuphepha lapho wenza isinqumo sokushayela.