Yini i-Indacaterol: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Indacaterol iyisithuthukisi se-bronchodilator esisebenza isikhathi eside esisiza ukuvula imigudu yakho yomoya ukuze kube lula ukuphefumula. Yenzelwe ngqo abantu abanesifo esingamahlalakhona sokuvinjelwa kwamaphaphu (i-COPD) abadinga usizo lansuku zonke lokugcina amaphaphu abo ehlanzekile futhi esebenza.

Lo muthi ungowesigaba esibizwa ngokuthi ama-long-acting beta2-agonists (LABAs). Cabanga ngayo njengomsizi omnene kodwa oqhubekayo osebenza ubusuku nemini ukugcina izindima zakho zokuphefumula zikhululekile futhi zivulekile, zikunikeze ukulawula okwengeziwe kwemisebenzi yakho yansuku zonke.

Yini i-Indacaterol?

I-Indacaterol ngumuthi wokuphefumula ongemuva kadokotela okhulula imisipha ezungeze imigudu yakho yomoya. Lapho le misipha ihlala ikhululekile, umoya ungangena futhi uphume kalula emaphashini akho usuku lonke.

Ngokungafani nezithuthukisi zokusiza ngokushesha ozisebenzisa ngesikhathi sezimo eziphuthumayo zokuphefumula, i-indacaterol isebenza kancane kancane futhi ngokuqinile. Kuthatha imizuzu emi-5 ukuqala ukusebenza futhi inikeza ukukhululeka amahora angu-24 agcwele ngomthamo owodwa nje wansuku zonke.

Umuthi uza njengempushana eyomile oyiphefumula ngqo emaphashini akho usebenzisa idivayisi ekhethekile yokuphefumula. Le ndlela yokulethwa iqinisekisa ukuthi umuthi ufika ngqo lapho udinga ukuya khona.

Isetshenziselwani i-Indacaterol?

I-Indacaterol isetshenziswa ikakhulukazi ekwelapheni okuhlala isikhathi eside kwe-COPD, okuhlanganisa i-chronic bronchitis kanye ne-emphysema. Isiza ukuvimbela ubunzima bokuphefumula bansuku zonke obuhambisana nalezi zimo.

Udokotela wakho angase akunikeze lo muthi uma uhlangabezana nokuphefumula okungajwayelekile, ukukhwehlela, noma lowo muzwa oqinile esifubeni sakho okwenza imisebenzi yansuku zonke ibe yinselelo. Ilusizo ikakhulukazi kubantu abadinga ukusekelwa kokuphefumula okuqhubekayo, usuku lonke.

Kubalulekile ukuqonda ukuthi i-indacaterol akuyona i-inhaler yokuhlenga. Akufanele uyisebenzise ukwelapha ukuhlaselwa kokuphefumula okungazelelwe noma izimpawu ezinzima ezidinga ukukhululeka ngokushesha.

Isebenza kanjani i-Indacaterol?

I-Indacaterol isebenza ngokugxila kuma-receptors athile emisipha yamaphaphu akho abizwa ngokuthi ama-beta2-adrenergic receptors. Lapho umuthi ubopha kula ma-receptors, uthumela isignali etshela imisipha ezungeze imigudu yakho yomoya ukuthi iphumule futhi ihlale ivulekile.

Lokhu kuthathwa njengomuthi onamandla amaphakathi ngokombono wokusebenza kwawo. Inikeza ukukhululeka okuthembekile, okuqhubekayo okuhlala amahora angama-24, okwenza kube namandla kune-bronchodilators esebenza ngokushesha kodwa ithambe kunezinye izindlela zokwelapha ezihlanganisiwe.

Umuthi futhi usiza ukunciphisa ukuvuvukala emoyeni wakho ngokuhamba kwesikhathi. Lesi senzo esiphindwe kabili sokuvula imigudu yomoya nokuthulisa ukucasuka sisiza ukudala indawo yokuphefumula enethezekile emaphashini akho.

Kufanele Ngiyithathe Kanjani I-Indacaterol?

Thatha i-indacaterol kanye ngosuku, ngesikhathi esifanayo nsuku zonke, usebenzisa idivayisi ekhethekile yokuphefumula enikeziwe. Isikhathi asidingi ukuhambisana nokudla, ngakho-ke ungasithatha nokudla noma ngaphandle kokudla.

Ngaphambi kokusebenzisa i-inhaler yakho, geza umlomo wakho ngamanzi uma usanda kudla noma uphuze okuthile ngaphandle kwamanzi. Lokhu kusiza ukuqinisekisa ukuthi umuthi ufika emaphashini akho ngempumelelo kunokuthi unamathele ezinhlayiyeni zokudla emlonyeni wakho.

Nansi indlela yokusebenzisa i-inhaler yakho ngendlela efanele:

1. Bamba i-inhaler iqonde phezulu bese ujika ikepisi uze uzwe ukuchofoza
2. Khipha umoya ngokugcwele, kude ne-inhaler
3. Beka izindebe zakho ngokuqinile emlonyeni
4. Phefumula ngokushesha, ujule nge-inhaler
5. Bamba umoya wakho imizuzwana eyi-10, bese ukhipha umoya kancane
6. Vala ikepisi bese ugeza umlomo wakho ngamanzi

Njalo geza umlomo wakho bese ukhafula amanzi ngemva kokusebenzisa i-inhaler yakho. Lesi sinyathelo esilula sisiza ukuvimbela ukucasuka komphimbo futhi sinciphisa ingozi yokuthuthukisa ukutheleleka nge-fungal emlonyeni wakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Indacaterol?

I-Indacaterol ngokuvamile iyimithi yokugcinwa yesikhathi eside ongase uyithathe izinyanga noma iminyaka. I-COPD yisimo esingamahlalakhona, ngakho ukwelashwa kwansuku zonke okuqhubekayo kusiza ukugcina ukusebenza kokuphefumula kwakho kanye nekhwalithi yempilo.

Udokotela wakho uzoqapha intuthuko yakho ngokuhlolwa okuvamile kanye nokuhlolwa kokusebenza kwamaphaphu. Bazolungisa uhlelo lwakho lokwelapha ngokusekelwe ekutheni usabela kahle kangakanani nokuthi izimpawu zakho zihlala zilawulwa yini.

Ungayeki ukuthatha i-indacaterol ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokuphazima kungabangela ukuthi ubunzima bakho bokuphefumula bubuye noma buqhubeke, okungenzeka kuholele ezinkingeni ezinzima.

Yiziphi Imiphumela Eceleni ye-Indacaterol?

Abantu abaningi bayayibekezelela i-indacaterol kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Ukuqonda ukuthi okulindelekile kungakusiza ukuthi uzizwe uqiniseka ngokwengeziwe ngemithi yakho.

Imiphumela emibi ejwayelekile abantu abaningi abayitholayo ihlanganisa:

• Ukukhwehlela okungase kuqhubeke imizuzu embalwa ngemva kokuphefumula
• Ukuvuvukala komphimbo noma ukuzwa ukuklwebheka
• Ikhanda elivame ukuba lincane futhi lesikhashana
• Ukuphuma noma ukuminyana emakhaleni
• Amajaqamba emisipha, ikakhulukazi emilenzeni yakho

Le miphumela ejwayelekile ivame ukuba mncane futhi ithambekele ekuthuthukiseni njengoba umzimba wakho uzivumela emithini emasontweni ambalwa okuqala.

Imiphumela emibi engavamile kodwa engathi sína idinga ukunakekelwa kwezempilo ngokushesha. Xhumana nodokotela wakho ngokushesha uma uhlangabezana:

• Ubuhlungu besifuba noma ukushaya kwenhliziyo okusheshayo, okungajwayelekile
• Isiyezi esikhulu noma ukuzwa sengathi ungaquleka
• Ukuthuthumela noma ukuzamazama okucasulayo
• Ubunzima bokulala noma ukukhathazeka okungajwayelekile
• Ukuqhubeka kwenkinga yokuphefumula noma ukuhlaselwa

Ukuphendula okungavamile kodwa okungathi sína komzimba kungenzeka, nakuba kungavamile. Funani usizo lwezempilo oluphuthumayo uma uthola ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo, noma uma uhlangabezana nobunzima obukhulu bokuphefumula ngemva kokusebenzisa i-inhaler.

Ubani Ongafanele Athole I-Indacaterol?

I-Indacaterol ayiphephile kuwo wonke umuntu, futhi izimo ezithile zezempilo zingenza ingafaneleki noma ibe yingozi. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi.

Akufanele usebenzise i-indacaterol uma une-asthma ngaphandle kwemithi eyengeziwe yokulawula. Ukusebenzisa i-LABA njenge-indacaterol yodwa ku-asthma kungakhuphula ngempela ingozi yokuhlaselwa yi-asthma okukhulu, okusongela impilo.

Abantu abanezimo ezithile zenhliziyo badinga ukucatshangelwa okukhethekile. Uma unezinkinga zenhliziyo ezingajwayelekile, isifo senhliziyo esibi, noma usanda kuba nesifo senhliziyo, udokotela wakho uzohlola izingozi nezinzuzo ngokucophelela.

Ezinye izimo ezingenza i-indacaterol ingafaneleki zihlanganisa:

• Umfutho wegazi ophezulu ongagadiwe kahle
• I-thyroid esebenza ngokweqile (i-hyperthyroidism)
• Isifo sikashukela esinzima ukusilawula
• Izifo zokuthuthumela
• Ukungezwani okwaziwayo ne-indacaterol noma imithi efanayo

Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile. Ngenkathi i-indacaterol ingakahlolisiswa kakhulu kwabesifazane abakhulelwe, udokotela wakho uzoyincoma kuphela uma izinzuzo zicacile ukuthi zidlula noma yiziphi izingozi ezingaba khona kuwe nomntwana wakho.

Amagama Omkhiqizo we-Indacaterol

I-Indacaterol itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Arcapta Neohaler iyona evame kakhulu e-United States. Kwamanye amazwe, ungase uyibone ithengiswa njenge-Onbrez Breezhaler noma i-Hirobriz Breezhaler.

Wonke lawo magama omkhiqizo aqukethe isithako esifanayo esisebenzayo, kodwa angase asebenzise amadivayisi okuhogela ahlukile kancane. Umuthi wakho ongumkhemisi angakukhombisa ukuthi ungawusebenzisa kanjani kahle idivayisi yakho ethile.

Izinhlobo ze-generic ze-indacaterol zingase zitholakale esikhathini esizayo, kodwa njengamanje, itholakala kuphela njengemithi yegama lomkhiqizo. Umshwalense wakho ungase uhluke ngokuya ngomkhiqizo odokotela wakho abakuyalela ngawo.

Ezinye izindlela ze-Indacaterol

Ezinye izindlela zokwelapha ezisebenza isikhathi eside zingahlinzeka ngezinzuzo ezifanayo uma i-indacaterol ingakulungeli. Udokotela wakho angase acabangele lezi ezinye izindlela ngokusekelwe ezidingweni zakho ezithile nokuthi usabela kanjani ekwelashweni.

Ezinye izinto ze-LABA zihlanganisa i-formoterol (Foradil, Perforomist) kanye ne-salmeterol (Serevent). Lezi zisebenza ngendlela efanayo ne-indacaterol kodwa zingase zidingeke ukuthi zithathwe kabili ngosuku esikhundleni sokuphindwa kanye.

Ama-antagonists e-muscarinic asebenza isikhathi eside (LAMAs) njenge-tiotropium (Spiriva) asebenza ngendlela ehlukile kodwa anikeza ukukhululeka okufanayo kwamahora angama-24. Abanye abantu benza ngcono nge-LAMAs kune-LABAs.

Imithi ehlanganisiwe ehlanganisa kokubili i-LABA ne-LAMA, njenge-glycopyrrolate/indacaterol (Utibron Neohaler), ingahlinzeka ngisho nokulawulwa okungcono kwezimpawu kwabanye abantu abane-COPD enzima kakhulu.

Ingabe i-Indacaterol Ingcono Kune-Formoterol?

Kokubili i-indacaterol ne-formoterol bangama-LABA asebenzayo, kodwa banezinto ezimbalwa eziyinhloko ezingenza enye ifaneleke kakhulu kuwe kunenye.

Inzuzo enkulu ye-Indacaterol ukulula - udinga kuphela ukuyithatha kanye ngosuku, kuyilapho i-formoterol ngokuvamile idinga ukulinganiswa kabili ngosuku. Lokhu kungakwenza kube lula ukunamathela enqanabeni lakho lokwelashwa futhi ugcine ukulawulwa kwezimpawu okuqhubekayo.

I-Formoterol iqala ukusebenza ngokushesha kune-indacaterol, ngokuvamile ngemizuzu engu-1-2 uma iqhathaniswa nemizuzu emi-5 ye-indacaterol. Kodwa-ke, njengoba kokubili kuyimithi yokugcinwa esikhundleni sokwelashwa kokuhlenga, lo mahluko awubalulekile ekusetshenzisweni kwansuku zonke.

Ngokuqondene nokusebenza kahle, izifundo zibonisa ukuthi kokubili imithi inikeza ukuthuthuka okufanayo ekusebenzeni kwamaphaphu kanye nekhwalithi yempilo. Udokotela wakho uzocabangela indlela yakho yokuphila, eminye imithi, nokuthi usabela kanjani ekwelashweni lapho ekhetha phakathi kwabo.

Imibuzo Evame Ukubuzwa Mayelana ne-Indacaterol

Ingabe i-Indacaterol iphephile kubantu abanezifo zenhliziyo?

I-Indacaterol idinga ukucatshangelwa ngokucophelela uma unesifo senhliziyo. Ngenkathi ngokuvamile iphephile kune-bronchodilators endala, ingase isathinta izinga lokushaya kwenhliziyo nomfutho wegazi.

Udokotela wakho uzohlola isimo sakho senhliziyo esithile futhi angase afune ukukuqapha eduze lapho uqala ukwelashwa. Bangase baqale ngomthamo ophansi noma batusa ukuqapha okwengeziwe kwenhliziyo ukuqinisekisa ukuthi umuthi uphephile kuwe.

Abantu abaningi abanesifo senhliziyo esizinzile bangasebenzisa i-indacaterol ngokuphepha, kodwa labo abanokuhlaselwa yinhliziyo kwakamuva, ukuhluleka kwenhliziyo okukhulu, noma izinkinga eziyingozi zokushaya kwenhliziyo bangase badinge ezinye izindlela zokwelashwa.

Kufanele ngenzeni uma ngiphuthelwa ngengozi ukusebenzisa i-Indacaterol eningi kakhulu?

Uma ngengozi uthatha umthamo owengeziwe we-indacaterol, ungangeni ekuqhumeni. Umthamo owodwa owengeziwe akunakwenzeka ukuthi ubangele izinkinga ezinkulu, kodwa ungase uhlangabezane nemiphumela engemihle eyengeziwe efana nokuthuthumela, ukushaya kwenhliziyo okusheshayo, noma ukukhathazeka.

Xhumana nodokotela wakho noma usokhemisi ukuze uthole isiqondiso, ikakhulukazi uma uhlangabezana nezimpawu ezikhathazayo. Bangakunika iseluleko sokuthi uzothatha nini umthamo wakho olandelayo ovamile nokuthi yini okufanele uyibheke.

Esimweni esingavamile sokuthatha imithamo eminingi eyengeziwe, funa ukunakekelwa kwezempilo ngokushesha. Izimpawu ezidinga ukunakekelwa okuphuthumayo zihlanganisa ubuhlungu obukhulu besifuba, izinguquko eziyingozi ekushayeni kwenhliziyo, noma ubunzima bokuphefumula obuya ngokuya bubi.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Indacaterol?

Uma uphuthelwa umthamo wakho wansuku zonke we-indacaterol, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe futhi uqhubeke nesheduli yakho evamile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela engemihle ngaphandle kokuhlinzeka ngomvuzo owengeziwe.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma usebenzise uhlelo lokusebenza lokukhumbuza amaphilisi. Ukulinganisa kwansuku zonke okuqhubekayo kubalulekile ekugcineni ukulawulwa okuhle kwezimpawu nge-COPD.

Ngingayeka nini ukuthatha i-Indacaterol?

Kufanele uyeke kuphela ukuthatha i-indacaterol ngaphansi kokuqondisa kukadokotela wakho. I-COPD yisimo esingamahlala-khona esidinga ukwelashwa okuqhubekayo kokugcina ukuvimbela izimpawu ukuthi zingabuyi noma zingabi zimbi.

Udokotela wakho angase acabange ukunciphisa noma ukuyeka i-indacaterol uma isimo sakho sihlale sizinzile isikhathi eside, noma uma ushintshela emuthini ohlukile ovumelana kangcono nezidingo zakho.

Ukuyeka kungazelelwe kungabangela ukuthi ubunzima bakho bokuphefumula bubuye phakathi kwamahora angu-24-48. Uma udinga ukuyeka nganoma yisiphi isizathu, udokotela wakho uzonikeza isiqondiso sokuthi ungenza kanjani lokho ngokuphepha nokuthi yiziphi ezinye izindlela zokwelapha ezingase zidingeke.

Ngingayisebenzisa i-Indacaterol Ngamanye Ama-Inhaler?

Yebo, i-indacaterol ivame ukusetshenziswa kanye namanye ama-inhaler njengengxenye yohlelo olubanzi lokwelashwa kwe-COPD. Abantu abaningi badinga imithi eminingi ukuze bathole ukulawulwa okuhle kwezimpawu.

Ungawasebenzisa ngokuphepha ama-inhaler okuhlenga afana ne-albuterol (ProAir, Ventolin) uma udinga ukukhululeka okusheshayo ebunzimeni bokuphefumula obuzumayo. Vele ulinde imizuzu embalwa phakathi kwama-inhaler ahlukene ukuze uqinisekise ukuthi ngamunye usebenza ngempumelelo.

Udokotela wakho uzoqondanisa yonke imithi yakho ukuze aqinisekise ukuthi isebenza kahle ndawonye. Njalo wazise ngayo yonke i-inhaler kanye nomuthi owusebenzisayo ukuze ugweme ukuxhumana okungenzeka noma ukwelashwa okuphindwe kabili.