Yini i-Ingenol: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Ingenol iyimithi esetshenziswa ngaphandle edokotela abayinqumayo ukwelapha i-actinic keratoses, okuyizindawo ezinzima, ezinamaqhuqhuva esikhumbeni sakho ezibangelwa ukulimala yilanga. Lokhu kwelashwa okusekelwe ku-gel kusebenza ngokugxila kumaseli esikhumba angajwayelekile angase athuthuke abe umdlavuza wesikhumba uma engelashwa.

Umuthi uvela esitshalweni esibizwa nge-Euphorbia peplus, esivame ukwaziwa ngokuthi i-milkweed noma i-petty spurge. Udokotela wakho wezifo zesikhumba angase ancome i-ingenol uma une-actinic keratoses eminingi endaweni eyodwa edinga ukwelashwa.

Yini i-Ingenol Esetshenziselwa Yona?

I-Ingenol ilapha i-actinic keratoses, lezo zindawo ezinzima, ezinjengamaphepha esihlabathi ezivela ezindaweni zesikhumba sakho ezivezwe yilanga. Lezi zindawo zibhekwa njengezandulela umdlavuza, okusho ukuthi zinamandla okuguquka zibe i-squamous cell carcinoma uma zingalashwa.

Ngokuvamile uzobona i-actinic keratoses ebusweni bakho, ekhanda, ezindlebeni, entanyeni, ezingalweni ezingaphambili, noma ezandleni. Lezi zindawo zithola ukuchayeka elangeni okuningi eminyakeni edlule. Izindawo zingase zizwe zinzima uma uzihlikihla ngomunwe wakho, futhi zingahluka ngombala kusuka ekubeni nombala wesikhumba kuya koku-reddish-brown.

Udokotela wakho ukhetha ngqo i-ingenol uma une-actinic keratoses eziningana ehlanganiswe ndawonye endaweni eyodwa yokwelapha. Lokhu kwenza kube ngcono kunokwelapha indawo ngayinye ngamanye amanye amasu afana nokufriza noma ukuklwebha.

Isebenza Kanjani i-Ingenol?

I-Ingenol isebenza ngenqubo yokusebenza kabili eqondisa amaseli esikhumba angajwayelekile ngenkathi igcina izicubu ezinempilo. Umuthi ubangela ukufa kwamaseli emaseleni alimele akha i-actinic keratoses, okwenza ukuba awohloke futhi achitheke.

Ngesikhathi esifanayo, i-ingenol yenza amasosha omzimba wakho ukuthi aqaphele futhi ahlaselwe noma yimaphi amaseli angajwayelekile asele endaweni elashwayo. Lokhu kusabela komzimba kusiza ukuqinisekisa ukuthi ukwelashwa kunembile futhi kunciphisa ithuba lokuthi i-keratoses ibuye.

Lokhu kuthathwa njengokwelashwa okunamandla okuqondene nendawo ethile. Imiphumela yenzeka ngokushesha uma iqhathaniswa neminye imithi eqondene nendawo ethile, kodwa lokhu futhi kusho ukuthi ungase uhlangabezane nokusabela kwesikhumba okuqaphelekayo ngesikhathi sokwelashwa.

Kufanele Ngiyithathe Kanjani I-Ingenol?

Ufaka i-ingenol ngqo endaweni yesikhumba ethintekile kanye ngosuku izinsuku ezilandelanayo ezi-2 noma ezi-3, kuye ngokuthi welapha kuphi. Ukuze welashwe ebusweni nasekhanda, uyisebenzisa izinsuku ezi-3. Ezindaweni zomzimba ezinjengezingalo noma izandla, ngokuvamile uyisebenzisa izinsuku ezi-2.

Ngaphambi kokufaka i-gel, geza izandla zakho kahle futhi uqinisekise ukuthi indawo yokwelashwa ihlanzekile futhi yomile. Khipha i-gel eyanele ukuze umboze yonke indawo yokwelashwa ngongqimba oluncane, bese uyihlikihla ngobumnene kuze kube yilapho inyamalala.

Akudingeki ukuthi uthathe lo muthi nokudla noma amanzi ngoba ufakwa esikhumbeni sakho. Nokho, kufanele ugweme ukuthola i-gel eduze kwamehlo akho, umlomo, noma yiziphi izilonda ezivulekile. Ngemuva kokufaka, geza izandla zakho ngokushesha ukuze uvimbele ukusabalalisa ngengozi umuthi kwezinye izindawo.

Faka i-gel ngesikhathi esifanayo nsuku zonke, okungcono kusihlwa. Lokhu kusiza ukunciphisa ukuchayeka elangeni endaweni elashwayo ngemuva nje kokufaka.

Kufanele Ngiyithathe Isikhathi Eside Kangakanani I-Ingenol?

Inkambo yokwelashwa nge-ingenol imfushane kakhulu - izinsuku ezi-2 kuya kwezi-3 nje sezizonke. Ngokungafani neminye imithi eminingi eqondene nendawo ethile edinga amasonto noma izinyanga zokusetshenziswa, i-ingenol isebenza ngokushesha futhi ngokuqinile ngalesi sikhathi esifushane.

Ngemuva kokuqeda umjikelezo wokwelashwa wezinsuku ezi-2 noma ezi-3, uyeka ukusebenzisa umuthi ngokuphelele. Isikhumba sakho sizoqhubeka nokusabela nokuphola emasontweni alandelayo, ngokuvamile kuthatha cishe amasonto ama-2 kuya kwangu-4 ukululama ngokugcwele.

Ngeke kudingeke ukuthi uphinde ukwelashwa ngaphandle uma i-actinic keratoses entsha ikhula endaweni efanayo, okungenzeka ukuthi kwenzeke ezinyangeni noma eminyakeni eminingi kamuva. Udokotela wakho wezikhumba uzoqapha isikhumba sakho futhi anqume ukuthi ngabe ukwelashwa okuzayo kuyadingeka yini.

Yiziphi Imiphumela Eceleni Ye-Ingenol?

Abantu abaningi bazobona ukusabela kwesikhumba endaweni ezelashwayo, okuyizimpawu zokuthi imithi isebenza kahle. Lokhu kusabela kuyingxenye yenqubo yokwelapha evamile njengoba isikhumba sakho silahla amaseli alimele.

Imiphumela emibi evame kakhulu ongase uyibone ihlanganisa ububomvu, ukuvuvukala, nobuhlungu endaweni ezelashwayo. Lezi zimpawu ngokuvamile ziqala phakathi nosuku olulodwa noma ezimbili ngemuva kokuqala ukwelashwa futhi zingahlala amasonto amaningana.

Nazi izindlela ongase uzibone, uqala ngalezo ezivamile kakhulu:

• Ububomvu nokuvuvukala okungabonakala kakhulu
• Ukuvuvukala endaweni ezelashwayo
• Ukuvutha noma ukushisa ngesikhathi nangemuva kokusebenzisa
• Ukuba namagxolo noma ukuba namathumba njengoba isikhumba esilimele selulama
• Ukuxebuka noma ukuhlukana kwesikhumba
• Ukuluma endaweni yokwelashwa
• Ubumnyama besikhashana noma ukukhanya kwesikhumba

Lezi zindlela zibonisa ukuthi i-ingenol iqondise amaseli angajwayelekile ngempumelelo. Ngenkathi zingase zibukeke zikhathaza, ngokuvamile azinabungozi futhi zizolunga njengoba isikhumba sakho selulama.

Imiphumela emibi engavamile kodwa ebucayi ingahlanganisa ukusabela okukhulu komzimba, yize lokhu kungavamile. Izimpawu zokusabela okukhulu zihlanganisa ukuqubuka okubanzi, ubunzima bokuphefumula, noma ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo.

Abanye abantu bangase babe nekhanda elibuhlungu, ukucasuka kwamehlo uma imithi ingena ngengozi eduze kwamehlo, noma izimpawu ezinjengomkhuhlane ngesikhathi sokwelashwa. Le miphumela yesikhashana futhi ngokuvamile ithambile.

Ubani Ongafanele Athathe I-Ingenol?

Akufanele usebenzise i-ingenol uma unenkinga yokungezwani nezithako zayo noma uma uke waba nokusabela okukhulu emithini efanayo yangaphandle esikhathini esidlule. Abantu abanezimo ezithile zesikhumba noma amasistimu omzimba awohlokile kungenzeka badinga ukugwema lokhu kwelashwa.

Udkt. wakho uzohlola ngokucophelela ukuthi i-ingenol ikufanele yini ngokuya ngomlando wakho wezokwelapha kanye nesimo sakho sempilo yamanje. Bazocabangela izinto ezinjengohlobo lwesikhumba sakho, ubukhulu be-actinic keratoses yakho, nanoma imiphi eminye imithi oyithathayo.

Izimo ezithile lapho i-ingenol ingase ingafaneleki zihlanganisa:

• Ukukhulelwa noma ukuncelisa (ukuphepha akukamiswanga)
• Izifo zesikhumba ezisebenzayo endaweni yokwelapha
• Amanxeba avulekile noma ukusikeka lapho udinga ukusebenzisa umuthi
• I-eczema enzima noma i-psoriasis endaweni yokwelapha
• Umlando wokuphendula kwesikhumba okunzima emithini esetshenziswa ngaphandle
• Ukusetshenziswa kwamanje kwemithi ethile ecindezela amasosha omzimba

Udermatologist wakho uzoxoxa ngalezi zinto nawe futhi asize ukunquma ukuthi i-ingenol iyona ndlela engcono kakhulu yokwelapha isimo sakho esithile.

Amagama Omkhiqizo we-Ingenol

I-Ingenol mebutate yayitholakala ngaphambilini ngaphansi kwegama lomkhiqizo elithi Picato emazweni amaningi, okuhlanganisa i-United States ne-Europe. Kodwa-ke, lo muthi wahoxiswa ngokuzithandela emakethe ngumenzi ngo-2020 ngenxa yokukhathazeka ngokuphepha.

Ukuhoxiswa kwenzeka ngemuva kokuthi izifundo zaphakamisa ingozi engase ikhule ye-skin cancer endaweni yokwelapha kwabanye abantu. Ngenxa yalokho, i-ingenol mebutate ayisatholakali ngokwentengiso yokwelapha i-actinic keratoses.

Uma ngabe ngaphambilini unikezwe i-Picato noma i-ingenol mebutate, udkt. wakho uzoncoma ezinye izindlela zokwelapha i-actinic keratoses yakho. Kunezinketho eziningi ezinye ezisebenzayo ezitholakalayo ezingabhekana nezinkinga zesikhumba sakho ngokuphepha.

Ezinye Izindlela ze-Ingenol

Njengoba i-ingenol ingasatholakali, udermatologist wakho unezinye izindlela eziningi zokwelapha i-actinic keratoses. Lezi zindlela ezihlukile zisebenza ngendlela ehlukile kodwa zingafinyelela imiphumela efanayo ekusuleni amaseli esikhumba angajwayelekile.

Ezinye izindlela zokwelapha zihlanganisa ukhilimu we-imiquimod, okhuthaza amasosha akho omzimba ukuthi alwe namaseli angajwayelekile, kanye nokhilimu we-fluorouracil, oqondiswe kumaseli ahlukanisa ngokushesha. Zombili zidinga izikhathi zokwelashwa ezinde kune-ingenol kodwa zinezimo zokuphepha ezisunguliwe kahle.

Izinketho zakho zokwelapha manje zihlanganisa:

• Ukhilimu we-Imiquimod (osetshenziswa izikhathi ezi-2-3 ngesonto amasonto amaningana)
• Ukhilimu we-Fluorouracil (osetshenziswa kabili ngosuku amasonto ama-2-4)
• I-Diclofenac gel (esetshenziswa kabili ngosuku izinyanga ezi-2-3)
• I-Cryotherapy (ukuqandisa nge-liquid nitrogen)
• I-Curettage (ukuklwebha izicubu ezingajwayelekile)
• I-Photodynamic therapy (ukwelashwa okusebenzisa ukukhanya)

Inketho ngayinye inezinzuzo ezihlukene kanye nezinto okufanele zicatshangelwe. Udokotela wakho wesikhumba uzokusiza ukhethe enye indlela engcono kakhulu esekelwe ezidingweni zakho ezithile, uhlobo lwesikhumba, kanye nezici zokuphila.

Imibuzo Evame Ukubuzwa Mayelana ne-Ingenol

Ingabe i-Ingenol iphephile kubantu abanesikhumba esibucayi?

I-Ingenol ayisatholakali ngenxa yokukhathazeka ngokuphepha okwaholela ekuhoxisweni kwayo emakethe ngo-2020. Ngesikhathi itholakala, yayingabangela ukusabela okukhulu kwesikhumba ngisho nakubantu abangenawo isikhumba esibucayi.

Uma unesikhumba esibucayi futhi udinga ukwelashwa kwe-actinic keratoses, udokotela wakho wesikhumba angatusa ezinye izindlela ezithambile njenge-diclofenac gel noma axoxe ngamashejuli okwelashwa aguquliwe ngeminye imithi yendawo ukunciphisa ukucasuka.

Kufanele ngenzeni uma ngake ngasebenzisa i-Ingenol?

Uma usebenzise i-ingenol (Picato) esikhathini esidlule, kubalulekile ukuqhubeka nokuhlolwa kwesikhumba njalo nodokotela wakho wesikhumba. Umuthi wahoxiswa ngenxa yokukhathazeka mayelana nengozi engase ikhule yomdlavuza wesikhumba ezindaweni zokwelapha.

Qapha izindawo lapho usebenzise khona i-ingenol nganoma yimaphi amabala amasha noma ashintshayo, ukukhula okungavamile, noma izinguquko zesikhumba eziqhubekayo. Bika noma yikuphi ukukhathazeka kudokotela wakho wesikhumba ngokushesha ukuze akwazi ukukuhlola futhi akusingathe ngendlela efanele.

Ziyini ezinye izindlela ezinhle kakhulu zamanje ze-Ingenol?

Ezinye izindlela ezivame ukunconywa zihlanganisa ukhilimu we-imiquimod kanye nokhilimu we-fluorouracil, kokubili okuneziqophamlando ezinde zokuphepha nokusebenza kahle. Udokotela wakho wezikhumba angase futhi ancome i-cryotherapy noma i-photodynamic therapy.

Ukukhetha okungcono kuncike ezintweni ezifana nenani nendawo ye-actinic keratoses yakho, uhlobo lwesikhumba sakho, kanye nokukhetha kwakho isikhathi sokwelashwa. Abanye abantu bakhetha ukwelashwa okufushane, okunamandla, kanti abanye bakhetha izinketho ezithambile, ezinobude obude.

Ngingakwazi yini Ukuthola I-Ingenol Ngezinhlelo Zokufinyelela Okhethekile?

I-Ingenol mebutate ayitholakali ngezinhlelo zokufinyelela okhethekile noma zokusetshenziswa ngomusa kusukela kumkhiqizi ozihoxise ngokuzithandela emakethe yomhlaba. Ukuhoxiswa bekubanzi futhi kusebenza kuwo wonke amazwe lapho yayivunyelwe khona ngaphambili.

Udokotela wakho wezikhumba angaxoxa ngezindlela ezikhona ezisekelwe ebufakazini ezitholakala kalula futhi ezinamaphrofayili okuphepha aqinisekisiwe okwelapha i-actinic keratoses ngempumelelo.

Ziqhathaniswa Kanjani Ukwelashwa Kwamanje Nalokho Okunikezwa yi-Ingenol?

Ukwelashwa kwamanje kwe-actinic keratoses kusebenza kahle kakhulu futhi kunenzuzo yedatha ebanzi yokuphepha. Ngenkathi i-ingenol inikeza isikhathi sokwelashwa esifushane kakhulu, ezinye izindlela ezitholakalayo zingafinyelela imiphumela efanayo noma engcono ngamaphrofayili obungozi aqondwe kahle.

Iziguli eziningi zithola ukuthi ukwelashwa kwamanje, ngenkathi kudinga izikhathi zokusebenzisa ezinde, kubangela ukusabela kwesikhumba okuncane futhi kunikeze imiphumela engabikezelwa kakhulu. Udokotela wakho wezikhumba angakusiza ukuthi uqonde ukuthi iyiphi inketho yamanje engasebenza kangcono esimweni sakho esithile.