Yini i-Insulin Lispro Protamine kanye ne-Insulin Lispro: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Insulin lispro protamine kanye ne-insulin lispro iyinhlanganisela yomuthi wesifo sikashukela osiza ukulawula amazinga kashukela egazini usuku lonke. Lo muthi ojovwayo uhlanganisa izinhlobo ezimbili ze-insulin ezisebenza ngamajubane ahlukene ukuze zilingise indlela umzimba wakho oqhamuka ngayo i-insulin ngokwemvelo.

Uma ulawula isifo sikashukela, ungase uzibuze ukuthi lo muthi ungangena kanjani ohlelweni lwakho lokwelashwa. Ukuqonda ukuthi isebenza kanjani nokuthi yini ongayilindela kungakusiza uzizwe uqiniseka ngokwengeziwe ngohambo lwakho lokunakekelwa kwesifo sikashukela.

Yini i-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Lo muthi yi-insulin exutshwe ngaphambili equkethe i-insulin esebenza ngokushesha kanye ne-insulin esebenza phakathi nendawo emjovweni owodwa. Ingxenye ye-insulin lispro isebenza ngokushesha ukuze ibhekane nokunyuka kukashukela egazini ngemva kokudla, kuyilapho ingxenye ye-protamine inikeza ukumbozwa okuhlala isikhathi eside phakathi kokudla kanye nobusuku bonke.

Cabanga ngayo njengesixazululo esithi ezimbili-kwesinye esikonga ukuthi ungadingi ukuthatha imijovo ehlukene. I-pancreas yakho ngokuvamile ikhipha i-insulin ngezindlela ezimbili: ukuqhuma okusheshayo uma udla kanye nenani eliqhubekayo ngosuku lonke. Lo muthi ohlanganisiwe uzama ukukopisha leyo ndlela yemvelo.

Umuthi uza njengokumiswa okubukeka kufiphele uma kuxutshwe kahle. Uzodinga ukuyigoqa ngobumnene noma ukuyinyakazisa ngaphambi komjovo ngamunye ukuze uqinisekise ukuthi izinhlobo ezimbili ze-insulin zisatshalaliswa ngokulinganayo.

Yini i-Insulin Lispro Protamine kanye ne-Insulin Lispro Esetshenziselwa Yona?

Le nhlanganisela ye-insulin isetshenziswa ikakhulukazi ukuphatha amazinga kashukela egazini kubantu abanesifo sikashukela mellitus, kokubili uhlobo 1 nohlobo 2. Isiza ukuvimbela ukuphakama okuyingozi nokuphansi okungenzeka uma umzimba wakho ungakhiqizi i-insulin eyanele noma ungakwazi ukuyisebenzisa ngempumelelo.

Udktela wakho angase akunike lo muthi uma udinga kokubili ukumbozwa kwe-insulin yesikhathi sokudla kanye nesendlalelo kodwa ukhetha ukujova okuncane. Lusizo ikakhulukazi kubantu abanezindlela zokudla eziqagelwayo futhi abafuna ukwenza lula inqubo yabo ye-insulin.

Abanye abantu basebenzisa lo muthi lapho besuka ekujoveni kwe-insulin okuhlukene beya ohlelweni olulula. Kungase futhi kunikezwe kanye neminye imithi yesifo sikashukela efana ne-metformin ukuhlinzeka ngokuqapha okubanzi ushukela wegazi.

Isebenza Kanjani I-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Lo muthi usebenza ngokunikeza umzimba wakho i-insulin ewudingayo ukuze uhambise ushukela ovela egazini lakho ungene emangqamuzaneni akho ukuze uthole amandla. I-insulin lispro esheshayo iqala ukusebenza kungakapheli imizuzu engu-15 yokujova futhi ifinyelela ezingeni eliphezulu cishe ngemuva kwehora elingu-1-2.

Ingxenye ye-protamine isebenza njenge-buffer enciphisa ukukhishwa kwe-insulin ethile, idale umphumela ophakathi nendawo ohlala amahora angu-12-24. Lokhu kukunikeza ukumbozwa kwe-insulin yesendlalelo okufana nalokho okunganikezwa yi-pancreas enempilo.

Lokhu kuthathwa njengomuthi we-insulin oqinile olinganiselwe onganciphisa kakhulu amazinga kashukela egazini. Indlela yokuhlanganisa isho ukuthi uthola kokubili isenzo se-insulin esisheshayo nesigcinakalayo, esingase sisebenze kahle kakhulu kodwa futhi sidinga ukuqapha ngokucophelela ukuvimbela izigameko zikashukela ophansi.

Kufanele Ngiyithathe Kanjani I-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Uzojova lo muthi ngaphansi kwesikhumba sakho (subcutaneously) usebenzisa isirinji, ipeni le-insulin, noma elinye idivayisi yokujova. Abantu abaningi bayithatha kabili ngosuku, ngokuvamile ngaphambi kwasekuseni nakusihlwa, nakuba udokotela wakho ezoqoka isikhathi esiqondile esikusebenzelayo.

Ngaphambi kokujova ngakunye, goqa ngobumnene ibhodlela phakathi kwezintende zakho noma utshekise ipeni phezulu naphansi okungenani izikhathi eziyi-10 ukuze uhlanganise i-insulin kahle. Uketshezi kufanele lubukeke lufiphele ngokulinganayo, lungabi sobala ngamaqhubu antantayo kuwo.

Khetha izindawo ezihlukene zokujova ngaso sonke isikhathi ukuvimbela izinkinga zesikhumba. Izindawo ezinhle zihlanganisa amathanga akho, izingalo eziphezulu, izinqe, noma isisu. Gwema izindawo ezinamaqhubu, ezibucayi, noma ezinamathanga avela emijovweni yangaphambilini.

Ungayithatha le insulin ngaphandle noma ngaphandle kokudla, kodwa zama ukugcina isikhathi esifanayo nokudla kwakho. Uma udla ukudla okukhulu kunokujwayelekile, udokotela wakho angase alungise umthamo wakho ngokufanele.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Abantu abaningi abanesifo sikashukela badinga ukuthatha i-insulin impilo yabo yonke, njengoba iyindlela yokufaka esikhundleni salokho umzimba wakho ongenakukukhiqiza ngokwanele. Lokhu akuyona into ongayeka ukuyithatha uma usuqalile, ngaphandle kokuthi udokotela wakho athola enye indlela yokwelapha ekusebenzelayo kangcono.

Nokho, umthamo wakho nesikhathi kungashintsha ngokuhamba kwesikhathi ngokuya ngezinto ezinjengokulawulwa kukashukela egazini lakho, izinguquko zesilinganiso somzimba, izinga lomsebenzi, nezinye izimo zempilo. Udokotela wakho uzoqapha intuthuko yakho ngokuhlolwa kwegazi okuvamile futhi alungise uhlelo lwakho lokwelapha njengoba kudingeka.

Abanye abantu bangashintshela kwezinye izinhlobo ze-insulin noma bangeze eminye imithi ohlelweni lwabo. Umgomo uhlala ukuthola inhlanganisela ekunikeza ukulawulwa okungcono kakhulu kukashukela egazini elinamiphumela emincane futhi evumelana nendlela yakho yokuphila.

Yiziphi Imiphumela Eceleni Ye-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Ushukela ophansi wegazi (i-hypoglycemia) umphumela oceleni ovamile futhi ongathi sína ongase uwuthole. Lokhu kungenzeka uma uthatha i-insulin eningi kakhulu, weqa ukudla, uzivocavo kakhulu kunokujwayelekile, noma uphuza utshwala ngaphandle kokudla ukudla okwanele.

Nawa amasignali kashukela ophansi wegazi okufanele uwabheke, kusukela ezimpawini ezilula kuya kwezikhathazayo:

• Ukuqhaqhazela, ukujuluka, noma ukuzizwa unovalo
• Indlala, isiyezi, noma ikhanda elibuhlungu
• Ukushaya kwenhliziyo okusheshayo noma ukuzizwa ukhathazekile
• Ukudideka, ubunzima bokugxilisa ingqondo, noma ukucasuka
• Ukubona okungacacile noma ukuzizwa ubuthakathaka
• Ezimweni ezinzima: ukulahlekelwa wukwazi noma ukuquleka

Uma uqaphela lezi zimpawu, hlola ushukela wakho wegazi uma kungenzeka futhi welaphe ushukela ophansi wegazi ngokushesha ngamaphilisi e-glucose, ijusi, noma uswidi. Ukuba nohlelo lokwelapha olulungile kungakusiza ukuthi usabele ngokushesha nangokuphephile.

Ezinye izinto ezingase zibe nemiphumela emibi ongase uzizwe zihlanganisa ukusabela endaweni yokujova. Lokhu kuvame ukuba mnene kodwa kungaba yinkinga:

• Ububomvu, ukuvuvukala, noma ukuluma lapho ukhona ujova khona
• Amaqhubu noma ukujiya kwesikhumba (i-lipodystrophy)
• Ukulimala noma ukuba nobumnene ezindaweni zokujova

Lezi zindlela zokuphendula zesikhumba zivame ukuthuthuka uma ujikeleza izindawo zokujova njalo futhi usebenzisa indlela efanele yokujova.

Abanye abantu bangase bakhuluphale ngenkathi bethatha i-insulin, njengoba umzimba wakho uba nempumelelo ekusebenziseni ushukela ukuze uthole amandla. Lokhu ngokuvamile kuyisibonakaliso sokuthi isifo sakho sikashukela silawulwa kangcono, nakuba kungase kukhathaze uma kubalulekile.

Imiphumela emibi engavamile kodwa engathi sína ingahlanganisa ukusabela okukhulu komzimba, nakuba lokhu kungavamile ngamalungiselelo e-insulin anamuhla. Izimpawu zizohlanganisa ukuqubuka okusabalale, ubunzima bokuphefumula, noma ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo.

Ubani Ongafanele Athatha I-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Akufanele uthathe lo muthi uma okwamanje unoshukela ophansi wegazi (i-hypoglycemia) noma uma unokungezwani komzimba ne-insulin lispro noma yiziphi ezinye izithako ezisetshenziswayo. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokukuyala lo muthi.

Izimo ezithile zezempilo zidinga ukuqapha okwengeziwe nokuqapha okuseduze uma usebenzisa le nhlanganisela ye-insulin. Udokotela wakho uzodinga ukwazi ngalezi zimo ukuze alungise ukwelashwa kwakho ngokuphephile:

• Isifo sezinso, esingathinta indlela umzimba wakho oqhubula ngayo i-insulin
• Izinkinga zesibindi, njengoba isibindi sakho sinendima ekulawuleni ushukela wegazi
• Isifo senhliziyo noma umfutho wegazi ophezulu
• Izinkinga ze-thyroid, ezingathinta ukulawulwa kukashukela wegazi lakho
• Izinkinga ze-adrenal gland
• Umlando weziqephu eziphansi zikashukela wegazi ezinzima

Uma unesinye salezi zimo, akusho ngempela ukuthi awukwazi ukusebenzisa lo muthi, kodwa udokotela wakho uzodinga ukukuqapha eduze futhi angase alungise umthamo wakho wokuqala.

Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile. Ngenkathi i-insulin ngokuvamile iphephile ngesikhathi sokukhulelwa, izidingo zakho ze-insulin zingashintsha kakhulu. Udokotela wakho uzosebenza nawe ukulungisa isimiso sakho ukuze sigcine wena nomntwana wakho niphilile.

Uma uneminyaka engaphezu kwengama-65, udokotela wakho angase akuqale ngomthamo ophansi njengoba abadala bengase bazwe kalula imiphumela ye-insulin futhi bangase babe nengozi enkulu yokuba noshukela wegazi ophansi kakhulu.

Amagama Omkhiqizo we-Insulin Lispro Protamine kanye ne-Insulin Lispro

Le nhlanganisela ye-insulin itholakala ngaphansi kwegama lomkhiqizo elithi Humalog Mix 75/25 kanye ne-Humalog Mix 50/50, kuye ngokuthi yisiphi isilinganiso esithile sezinhlobo ezimbili ze-insulin. Izinombolo zibhekisela ezingxenyeni zephesenti yento ngayinye ye-insulin engxubeni.

I-Humalog Mix 75/25 iqukethe i-75% ye-insulin lispro protamine (esebenza isikhashana) kanye ne-25% ye-insulin lispro (esebenza ngokushesha). I-Humalog Mix 50/50 inezingxenye ezilinganayo zohlobo ngalunye. Udokotela wakho uzokhetha isilinganiso esihambisana kangcono namaphethini akho kashukela wegazi nendlela yakho yokuphila.

Le mithi yenziwa yi-Eli Lilly and Company futhi itholakala ngezinhlobo ezahlukene ezihlanganisa ama-vials okusetshenziswa ngemijovo kanye namapeni agcwaliswe ngaphambili ukuze kube lula ukujova.

Ezinye izindlela ze-Insulin Lispro Protamine kanye ne-Insulin Lispro

Ezinye izinketho ze-insulin ezixutshwe ngaphambili ziyatholakala uma le nhlanganisela ethile ingasebenzi kahle kuwe. Lezi ezinye izindlela zisebenza ngendlela efanayo kodwa zingase zibe nesikhathi esihlukile noma ubude besenzo.

Ezinye izinhlanganisela ze-insulin ezixutshwe ngaphambili zihlanganisa i-NovoLog Mix (i-insulin aspart protamine kanye ne-insulin aspart) kanye ne-Humulin 70/30 (i-NPH insulin kanye ne-insulin ejwayelekile). Ngayinye inezici ezehlukile kancane mayelana nokuthi iqala ngokushesha kangakanani ukusebenza nokuthi ihlala isikhathi esingakanani.

Udkt wakho angase futhi acabangele ukuhlukanisa i-insulin yakho ibe imijovo ngamanye usebenzisa i-insulin esebenza isikhathi eside (njenge-insulin glargine noma i-insulin detemir) ukuze umboze isizinda kanye ne-insulin esebenza ngokushesha (njenge-insulin lispro noma i-insulin aspart) ukudla.

Ezinye izindlela ezingezona ze-insulin zikhona kubantu abanesifo sikashukela sohlobo 2, okuhlanganisa imithi efana ne-metformin, sulfonylureas, noma ezinye izinketho ezintsha njenge-GLP-1 agonists. Kodwa-ke, lokhu kungase kunganikezi ukulawulwa okwanele kukashukela egazini kuwo wonke umuntu, ikakhulukazi labo abanesifo sikashukela sohlobo 1.

Ingabe i-Insulin Lispro Protamine kanye ne-Insulin Lispro Ingcono Kune-Humulin 70/30?

Zombili le mithi iyasebenza i-insulin exutshwe ngaphambili, kodwa zisebenza ngamajubane ahlukene futhi zingase zivumelane nezindlela zokuphila ezihlukene. I-Insulin lispro protamine kanye ne-insulin lispro isebenza ngokushesha kune-Humulin 70/30, okusho ukuthi ungayijova eduze nesikhathi sokudla futhi ingase inikeze ukulawulwa okungcono kwama-spikes kashukela egazini ngemva kokudla.

I-Humulin 70/30 iqukethe i-insulin ejwayelekile kanye ne-NPH insulin, eqala ukusebenza kancane kodwa ingase ihlale isikhathi eside. Lokhu kungasiza uma unezindlela zokudla eziqagelwayo kakhulu futhi ukhetha umphumela ohlala isikhathi eside.

Ukukhetha okuthi

Udktela wakho uzocabangela izinto ezifana nokulawulwa kwakho kwamanje ushukela wegazi, lapho uvame ukudla khona ukudla, izinga lakho lomsebenzi, kanye nanoma yimaphi imiphumela emibi oyithole ngamanye ama-insulin ukusiza ukunquma ukuthi iyiphi inketho engasebenza kahle kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Insulin Lispro Protamine kanye ne-Insulin Lispro

Ingabe i-Insulin Lispro Protamine kanye ne-Insulin Lispro iphephile ezigulini zenhliziyo?

Yebo, le nhlanganisela ye-insulin ngokuvamile iphephile kubantu abanezifo zenhliziyo, futhi ukulawulwa okuhle kukashukela wegazi empeleni kusiza ukuvikela inhliziyo yakho nemithambo yegazi. Kodwa-ke, uzodinga ukuqapha okuseduze ngoba imithi yenhliziyo ngezinye izikhathi ingathinta amazinga kashukela wegazi.

Udktela wakho uzoqondanisa ukunakekelwa kwakho isifo sikashukela nenhliziyo ukuze aqinisekise ukuthi yonke imithi yakho isebenza kahle ndawonye. Bangase badinge ukulungisa imithamo noma isikhathi njengoba ukwelashwa kwakho kuqhubeka. Okubalulekile ukugcina amazinga kashukela wegazi ezinzile, okunciphisa ukucindezeleka ohlelweni lwakho lwe-cardiovascular.

Ngingenzani uma ngiphuthelwa ngokungazi ukusebenzisa i-Insulin Lispro Protamine kanye ne-Insulin Lispro eningi kakhulu?

Uma uzifake i-insulin eningi kakhulu, ungesabi, kodwa thatha isinyathelo ngokushesha ukuvimbela ushukela wegazi ophansi kakhulu. Hlola i-glucose yakho yegazi ngokushesha uma kungenzeka, bese uqala ukwelapha ushukela wegazi ophansi ngisho noma uzizwa ulungile okwamanje.

Yidla noma uphuze okuthile okune-carbohydrate esheshayo njengamaphilisi e-glucose, ijusi lezithelo, noma i-soda ejwayelekile. Landela ngesnakhi esihlanganisa amaprotheni nama-carbohydrate ahlala isikhathi eside. Qapha ushukela wakho wegazi ngokucophelela amahora ambalwa alandelayo, njengoba umphumela ungahlala isikhathi eside.

Xhumana nodokotela wakho noma umhlinzeki wokunakekelwa kwezempilo ukuze ubazise ngalokho okwenzekile futhi uthole isiqondiso sokugada nokulungiswa kwemithamo yezitsha ezizayo. Uma uhlangabezana nezimpawu ezinzima njengokudideka, ukuquleka, noma ukulahlekelwa ukwazi, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha.

Ngingenzani uma ngiphuthelwa umthamo we-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Uma uqaphela ukuthi uphuthelwe umthamo ngaphakathi kwamahora ambalwa esikhathini sakho esivamile sokujova, ungawuthatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekudlule amahora ambalwa noma useduze nomthamo wakho olandelayo ohleliwe, xhumana nodokotela wakho ukuze uthole isiqondiso esikhundleni sokuphinda.

Qapha ushukela wakho wegazi kaningi uma uphuthelwe umthamo, njengoba amazinga akho angase abe phezulu kunokujwayelekile. Ungase udinge ukulungisa ukudla kwakho noma izinga lomsebenzi ukuze usize ukuphatha ushukela wakho wegazi kuze kube yilapho umjovo wakho olandelayo ohleliwe.

Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ubuyisele umthamo ophuthelwe, ngoba lokhu kungabangela ushukela wegazi ophansi oyingozi. Kungcono ukuba noshukela wegazi ophezulu kancane okwesikhashana kunokubeka engozini isigameko esibi sikashukela wegazi ophansi.

Ngingayeka nini ukuthatha i-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Abantu abaningi abanesifo sikashukela badinga ukwelashwa nge-insulin isikhathi eside, ikakhulukazi labo abanesifo sikashukela sohlobo 1 okuthi imizimba yabo ingakhiqizi i-insulin ngokwemvelo. Kodwa-ke, abanye abantu abanesifo sikashukela sohlobo 2 bangase bakwazi ukunciphisa noma bayeke i-insulin uma benza izinguquko ezinkulu zokuphila noma uma udokotela wabo ethola eminye imithi esebenza kangcono.

Ungalokothi uyeke ukuthatha i-insulin ngokwakho, ngisho noma amazinga akho kashukela egazi ebelunge. Udokotela wakho udinga ukuhlola ukuphathwa kwakho konke kwesifo sikashukela futhi angase afune ukukuqapha eduze ngesikhathi sokushintsha kwemithi.

Abanye abantu bangase bashintshele ezinhlotsheni ezihlukene ze-insulin noma ukwelashwa okuhlanganisiwe njengoba izidingo zabo zishintsha ngokuhamba kwesikhathi. Umgomo uhlala ukugcina ukulawulwa okuhle koshukela wegazi ngenkathi kunciphisa imiphumela emibi futhi kufanele ukwelashwa kwakho ekuphileni kwakho.

Ngingazivocavoca ngenkathi ngithatha i-Insulin Lispro Protamine kanye ne-Insulin Lispro?

Yebo, ukuzivocavoca njalo empeleni kuyakhuthazwa futhi kuyasiza ekuphathweni kwesifo sikashukela, kodwa kudinga ukuhlela okuthile uma uthatha i-insulin. Ukuzikhandla ngokomzimba kunganciphisa ushukela wakho wegazi, ngakho kungase kudingeke ulungise umthamo wakho we-insulin, udle ama-carbohydrate engeziwe, noma uhlele ukuzivocavoca kwakho ngokucophelela.

Hlola ushukela wakho wegazi ngaphambi, ngesikhathi (semisebenzi ende), nangemva kokuzivocavoca ukuze uqonde ukuthi umzimba wakho usabela kanjani. Udokotela wakho angakusiza ukuthi wakhe uhlelo lokuzivocavoca olusebenza ngokuphepha ngohlelo lwakho lwe-insulin.

Qala kancane uma umusha ekuzivocavoceni, futhi uhlale uphethe umthombo wama-carbohydrate asebenza ngokushesha nawe uma ushukela wakho wegazi wehla kakhulu ngesikhathi noma ngemva kokuzikhandla ngokomzimba.