Yini i-Isocarboxazid: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Isocarboxazid iyimithi yokucindezela ebekwe ngudokotela engaphansi kwezigaba zemithi ebizwa ngokuthi ama-monoamine oxidase inhibitors (MAOIs). Isebenza ngokuvimba i-enzyme ebuchosheni bakho ehlukanisa amakhemikhali athile alawula imizwa, okuvumela lezi zinto zemvelo ukuthi zihlale zisebenza isikhathi eside futhi zisize ukuthuthukisa imizwa yakho.

Le mithi ivamise ukubekwa uma ezinye izidambisi zokucindezeleka zingasebenzanga kahle kuwe. Ngenkathi ingasebenza kahle kakhulu, idinga ukuqashwa ngokucophelela kanye nemikhawulo yokudla ngenxa yokuthi isebenzisana kanjani nokudla okuthile neminye imithi.

Yini i-Isocarboxazid Esetshenziselwa Yona?

I-Isocarboxazid isetshenziselwa ikakhulukazi ukwelapha ukuphazamiseka okukhulu kokucindezeleka, ikakhulukazi ezimweni lapho ezinye izidambisi zokucindezeleka zingaphumelelanga. Udokotela wakho angase ancome le mithi uma uzamile ezinye izindlela zokwelapha eziningana ngaphandle kokuthola usizo oludingayo.

Ngezinye izikhathi odokotela babeka i-isocarboxazid kwezinye izimo ezinjengokuphazamiseka kokwesaba noma ukuphazamiseka kokukhathazeka komphakathi, nakuba lokhu kuthathwa njengokusebenzisa “ngaphandle kwelebula”. Lokhu kusho ukuthi imithi ingasiza kulezi zimo ngisho noma yayingenzelwe zona ekuqaleni.

Ngenxa yokuthi i-isocarboxazid iyimithi enamandla enezidingo ezithile, ivame ukugcinelwa abantu abangazange basabele kahle ezidambisweni zokucindezeleka ezintsha, eziphephile. Udokotela wakho uzoqaphela ngokucophelela ukuthi ngabe izinzuzo zidlula izingozi esimweni sakho esithile.

Isebenza Kanjani i-Isocarboxazid?

I-Isocarboxazid isebenza ngokuvimba i-monoamine oxidase, i-enzyme ehlukanisa ngokwemvelo amakhemikhali alawula imizwa ebuchosheni bakho njenge-serotonin, i-dopamine, ne-norepinephrine. Uma le enzyme ivinjelwe, la makhemikhali abalulekile ahlala esebenza isikhathi eside, okungasiza ukuthuthukisa imizwa yakho futhi kunciphise izimpawu zokucindezeleka.

Lo muthi uthathwa njengomuthi oqinile wokulwa nokucindezeleka, kodwa futhi uyinkimbinkimbi kunezinketho ezintsha. Isenzo sokuvimba sithinta umzimba wakho wonke, hhayi nje ubuchopho bakho, yingakho udinga ukuqapha ukuthi udlani nokuthi yimiphi eminye imithi oyithathayo ngenkathi uyisebenzisa.

Kuvamile ukuthatha amasonto amaningana ukuzwa izinzuzo eziphelele ze-isocarboxazid. Ungase uqaphele ukuthuthuka emazingeni akho amandla kuqala, kulandelwe ukuthuthuka kancane kancane emoyeni wakho kanye nenhlalakahle iyonke.

Kufanele Ngiyithathe Kanjani I-Isocarboxazid?

Thatha i-isocarboxazid ngendlela eqondile udokotela wakho ayiyalayo, ngokuvamile izikhathi ezi-2 kuya kwezi-4 ngosuku ngaphandle kokudla noma ngaphandle kokudla. Ungayithatha ngobisi noma ngamanzi, futhi akukho mfuneko ethile yokudla ngaphambi kokuyithatha, nakuba ukuyithatha nokudla kungasiza uma uhlangabezana nesisu esicasukile.

Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Uma uthatha imithamo eminingi, yihlukanise ngokulinganayo usuku lonke njengoba kuqondiswe udokotela wakho.

Into ebaluleke kakhulu okufanele uyikhumbule ukulandela imikhawulo yokudla eqinile ngenkathi uthatha lo muthi. Uzodinga ukugwema ukudla okunothe nge-tyramine, njengoshizi omdala, inyama elashwe, ukudla okubilisiwe, neziphuzo ezithile ezinotshwala, ngoba lokhu kungabangela ukukhuphuka okuyingozi komfutho wegazi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Isocarboxazid?

Ubude bokwelashwa nge-isocarboxazid buhluka kakhulu kumuntu nomuntu, kodwa abantu abaningi badinga ukuyithatha izinyanga eziningana kuya onyakeni noma ngaphezulu. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngendlela osabela ngayo emuthini kanye nezimo zakho.

Kubalulekile ukungayeki ukuthatha i-isocarboxazid ngokuzumayo, ngisho noma uzizwa ungcono. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa kanye nezinguquko eziyingozi emfutho wakho wegazi nomoya wakho.

Uma sekuyisikhathi sokuyeka umuthi, udokotela wakho uzokwehlisa kancane kancane umthamo wakho emasontweni amaningana. Le nqubo, ebizwa ngokuthi ukunciphisa, isiza umzimba wakho ukuthi uzivumelanise ngokuphephile futhi inciphisa ubungozi bemiphumela yokuhoxisa.

Yini Imiphumela Eceleni ye-Isocarboxazid?

Njengayo yonke imithi, i-isocarboxazid ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi ejwayelekile ongase uyithole ihlanganisa:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Umlomo owomile
• Ukuqunjelwa
• Ubunzima bokulala noma ukulala
• Isicanucanu noma isisu esibuhlungu
• Ikhanda
• Ushintsho ekudleni noma esisindweni
• Imiphumela emibi yocansi

Le miphumela emibi ejwayelekile ivame ukuthuthuka njengoba umzimba wakho uzivumelanisa nomuthi, ngokuvamile emasontweni ambalwa okuqala kokwelashwa.

Imiphumela emibi engathi sína idinga ukunakekelwa kwezempilo ngokushesha futhi ihlanganisa:

• Ikhanda elibuhlungu elinamandla nentamo eqinile
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ubuhlungu besifuba
• Ukwehla kwegazi okukhulu, okungazelelwe
• Isicanucanu esibi kakhulu nokuhlanza
• Ukudideka noma ukucasuka
• Ukuphuzi kwesikhumba noma amehlo

Lezi zimpendulo ezingathi sína azivamile kodwa zingaba yingozi ekuphileni, ngakho kubalulekile ukufuna usizo lwezokwelapha ngokushesha uma uzithola.

Imiphumela emibi engavamile kodwa engathi sína ingahlanganisa izinkinga zesibindi, izifo zegazi, kanye nesimo esibizwa ngokuthi i-serotonin syndrome uma ihlanganiswe neminye imithi ethile. Udokotela wakho uzokuhlola njalo ngezivivinyo zegazi ukuze abambe noma yiziphi izinkinga ezingaba khona ekuqaleni.

Ubani Ongafanele Athathwe I-Isocarboxazid?

I-Isocarboxazid ayiphephile kuwo wonke umuntu, futhi kunezimo eziningana ezibalulekile lapho lo muthi kufanele ugwenywe khona. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha nemithi yamanje ngaphambi kokuyinika.

Akufanele uthathe i-isocarboxazid uma:

• Uthathe ezinye izidakamizwa ze-MAOIs noma ezinye izidambisi zokucindezeleka ezinsukwini eziyi-14 ezedlule
• Isifo senhliziyo esibi noma umfutho wegazi ophezulu ongagadiwe
• Isifo sesibindi noma umlando wezinkinga zesibindi
• Umkhuhlane wobuchopho noma ukulimala ekhanda
• Isifo sezinso
• I-thyroid esebenza ngokweqile
• Umlando wokushaywa unhlangothi

Lo muthi udinga ukuqapha okwengeziwe uma uneminyaka engaphezu kwengama-65, njengoba ungase uzwe imiphumela yawo kalula futhi uthambekele ekuqhumeni nasekuweni.

Ukukhulelwa nokuncelisa banikeza izinto ezikhethekile okufanele zicatshangelwe. Ngenkathi i-isocarboxazid ingakahlolisiswa ngokujulile kwabesifazane abakhulelwe, ngokuvamile iyagwenywa ngesikhathi sokukhulelwa ngaphandle uma izinzuzo zicacile ukuthi zidlula izingozi. Uma uhlela ukukhulelwa noma uncelisa, xoxa lokhu ngokujulile nodokotela wakho.

Amagama Omkhiqizo we-Isocarboxazid

I-Isocarboxazid itholakala ngaphansi kwegama lomkhiqizo elithi Marplan e-United States. Lolu uhlobo oluvame kakhulu olubhalwe ngemithi, nakuba izinhlobo ezivamile nazo zingatholakala.

Noma ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile, isithako esisebenzayo nokusebenza kwayo kuyafana. Umuthi wakho womuthi ungakutshela ukuthi iyiphi inguqulo oyitholayo futhi uphendule noma yimiphi imibuzo mayelana nomkhiqizi othile.

Ezinye izindlela ze-Isocarboxazid

Uma i-isocarboxazid ingakulungele, kukhona ezinye izindlela zokwelapha ezitholakalayo. Udokotela wakho angase acabangele ezinye izinhlobo zezidambisi zokucindezeleka ezisebenza ngendlela ehlukile futhi ezinemingcele emincane yokudla.

Ezinye izindlela ezivamile zihlanganisa:

• Izithiyo ze-serotonin reuptake ezikhethiwe (SSRIs) njenge-sertraline noma i-escitalopram
• Izithiyo ze-serotonin-norepinephrine reuptake (SNRIs) njenge-venlafaxine noma i-duloxetine
• Izidambisi zokucindezeleka ze-Tricyclic njenge-amitriptyline noma i-nortriptyline
• Izidambisi zokucindezeleka ezingavamile njenge-bupropion noma i-mirtazapine

Ukwelashwa okungekona okwemithi njenge-psychotherapy, ikakhulukazi i-cognitive-behavioral therapy, kungasebenza kahle kakhulu ekucindezelekeni kungaba yodwa noma kuhlangene nemithi.

Ukukhetha okunye kuncike ezimpawini zakho ezithile, umlando wakho wezokwelapha, eminye imithi oyithathayo, kanye nezintandokazi zakho mayelana nezindlela zokwelapha.

Ingabe i-Isocarboxazid ingcono kune-Phenelzine?

Kokubili i-isocarboxazid ne-phenelzine yi-MAOIs esebenza ngendlela efanayo, kodwa zinezinye izinto ezingenza enye ikufaneleke kakhulu kunenye. Akukho ngempela okuthi "kungcono" - kuncike ekuphenduleni kwakho komuntu ngamunye kanye nephrofayili yemiphumela emibi.

I-Isocarboxazid ivame ukuba ngaphansi kokuthulisa kuno-phenelzine, okungase kukhetheke uma ukhathazekile ngobuthongo basemini. Kodwa-ke, i-phenelzine ingasebenza kahle kakhulu ezinhlotsheni ezithile zokucindezeleka, ikakhulukazi lezo ezinezimpawu zokukhathazeka ezivelele.

Zombili le mithi idinga imikhawulo efanayo yokudla futhi inemiphumela emibi efanayo. Udokotela wakho uzocabangela izinto ezinjengezimpawu zakho ezithile, indlela yokuphila, nokuthi usabele kanjani eminye imithi lapho ekhetha phakathi kwazo.

Imibuzo Evame Ukubuzwa Mayelana ne-Isocarboxazid

Ingabe i-Isocarboxazid iphephile ezigulini zenhliziyo?

I-Isocarboxazid ingaba yingozi kubantu abanezifo zenhliziyo ngoba ingathinta umfutho wegazi nesigqi senhliziyo. Uma unesifo senhliziyo, udokotela wakho uzodinga ukulinganisa ngokucophelela izinzuzo nezingozi.

Abantu abanezifo zenhliziyo ezinzima, umfutho wegazi ophezulu ongagadiwe, noma umlando wokuhlaselwa yinhliziyo ngokuvamile akufanele bathathe i-isocarboxazid. Kodwa-ke, uma unezimo zenhliziyo ezilula, ezilawulwa kahle, udokotela wakho angase akucabangele ngokuqapha okuseduze kakhulu.

Ngingenzani uma ngithatha i-Isocarboxazid eningi ngengozi?

Uma ngabe uthathe i-isocarboxazid eningi ngengozi, xhumana nezinsizakalo eziphuthumayo noma ukulawulwa kwezinto ezinobuthi ngokushesha. Ungalindi ukubona ukuthi uzizwa ulungile yini - izimpawu zokweqisa umthamo zingahlehliswa futhi zibe yingozi empilweni.

Izimpawu zokweqisa umthamo zingabandakanya isiyezi esikhulu, ukuquleka, ukushaya kwenhliziyo okusheshayo, ikhanda elibuhlungu kakhulu, ukudideka, noma ubunzima bokuphefumula. Isikhathi sibalulekile ekwelapheni ukweqisa umthamo, ngakho funa usizo ngokushesha ngisho noma uzizwa ulungile ekuqaleni.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Isocarboxazid?

Uma uphuthelwa umthamo we-isocarboxazid, yithathe ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusebenzisa umhleli wamaphilisi noma ukusetha izikhumbuzi zocingo ukukusiza ukuthi uhlale emgwaqeni.

Ngingayeka nini ukuthatha i-Isocarboxazid?

Kufanele uyeke kuphela ukuthatha i-isocarboxazid ngaphansi kokuqondisa kukadokotela wakho. Noma ngabe uzizwa ungcono kakhulu, ukuyeka kungazelelwe kungadala izimpawu zokuhoxiswa kanye nezinguquko eziyingozi zengcindezi yegazi.

Udokotela wakho uzokwehlisa kancane umthamo wakho emasontweni amaningana uma sekuyisikhathi sokuyeka. Le nqubo ingathatha inyanga noma ngaphezulu, kuye ngokuthi usuthatha isikhathi esingakanani umuthi nokuthi umzimba wakho usabela kanjani.

Ngemuva kokuyeka i-isocarboxazid, uzodinga ukuqhubeka nokulandela imikhawulo yokudla okungenani amasonto amabili ukuvumela umuthi ukuthi ususwe ngokuphelele ohlelweni lwakho.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Isocarboxazid?

Kufanele ugweme utshwala ngenkathi uthatha i-isocarboxazid, ikakhulukazi izinhlobo ezithile ezinjengewayini elibomvu, ubhiya, nemimoya emidala. Lezi ziphuzo ezinotshwala ziqukethe i-tyramine, engasebenzisana ngendlela eyingozi nomuthi wakho futhi idale umfutho wegazi ophezulu kakhulu.

Ngisho namanani amancane otshwala angaba yinkinga, futhi ukusebenzisana kungaba okungalindelekile. Kuphephe kakhulu ukugwema utshwala ngokuphelele ngenkathi uthatha i-isocarboxazid kanye namaviki amabili ngemva kokuyeka umuthi.