Yini i-Isosorbide Dinitrate: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Isosorbide dinitrate iyikhambi lenhliziyo elisiza ekuvikeleni ubuhlungu besifuba (i-angina) ngokukhulula nokwandisa imithambo yakho yegazi. Lokhu kuvumela igazi eliningi nomoya-mpilo ukuthi ageleze emsipheni wakho wenhliziyo, kunciphisa ukucindezeleka enhliziyweni yakho ngesikhathi sokuzivocavoca noma ukucindezeleka ngokomzwelo.

Cabanga ngakho njengokunikeza imithambo yegazi yenhliziyo yakho usizo lokuhlala ivulekile futhi iguquguquka. Isetshenziswe ngokuphepha amashumi eminyaka ukusiza abantu abanezifo zenhliziyo ukuthi baphile ngokunethezeka futhi bahlale bekhuthele.

Yini i-Isosorbide Dinitrate?

I-Isosorbide dinitrate ingeyeqembu lemithi ebizwa ngokuthi ama-nitrate. Isebenza ngokuguqulela ku-nitric oxide emzimbeni wakho, okuyinto engokwemvelo esiza imithambo yegazi ukuthi ikhululeke futhi yande.

Lo muthi uza ngezinhlobo eziningana ezihlanganisa amaphilisi avamile, amaphilisi akhishwe isikhathi eside, kanye namaphilisi angaphansi kolimi ancibilika ngaphansi kolimi lwakho. Uhlobo olungaphansi kolimi lusebenza ngokushesha, ngokuvamile ngemizuzu engu-2-5, okwenza kube usizo ekuqede ubuhlungu ngokushesha ngesikhathi sokuhlaselwa yisifuba.

Udokotela wakho angase akunikeze lo muthi njengengxenye yohlelo lokunakekelwa kwenhliziyo olubanzi. Ivame ukusetshenziswa kanye neminye imithi yenhliziyo ukukunikeza ukuvikelwa okungcono kakhulu kanye nokukhululeka kwezimpawu.

Yini i-Isosorbide Dinitrate Esetshenziselwa Yona?

Ukusetshenziswa okuyinhloko kwe-isosorbide dinitrate ukuvimbela ukuhlaselwa yi-angina, okuyizigameko zobuhlungu besifuba obubangelwa ukuncipha kokugeleza kwegazi enhliziyweni yakho. Ilusizo ikakhulukazi kubantu abanesifo semithambo yenhliziyo lapho imithambo enikezela inhliziyo iba mncane.

Udokotela wakho angase akunikeze lo muthi uma uzwa ubuhlungu besifuba ngesikhathi sokuzivocavoca njengokuhamba, ukukhuphuka izitebhisi, noma ngisho nangokucindezeleka ngokomzwelo. Kungasiza futhi uma unezinhlungu zesifuba ezenzeka ngendlela ebonakalayo, njengangesikhathi esithile sosuku noma ngemva kokudla.

Kwezinye izimo, odokotela banikeza i-isosorbide dinitrate yokuhluleka kwenhliziyo, lapho isiza ukunciphisa umsebenzi wenhliziyo yakho ngokwenza kube lula ukuthi igazi ligeleze emzimbeni wakho.

Isebenza Kanjani I-Isosorbide Dinitrate?

Lo muthi uthathwa njengomuthi wenhliziyo onamandla aphakathi nendawo osebenza ngokwandisa (ukukhulisa) imithambo yakho yegazi. Uma uwuthatha, umuthi uguqulwa ube yi-nitric oxide, ebonisa imisipha ebushelelezi ezindongeni zemithambo yakho yegazi ukuthi iphumule.

Njengoba imithambo yakho yegazi iphumula futhi yanda, inhliziyo yakho akudingeki isebenze kanzima ukuze ipompe igazi ngayo. Lokhu kunciphisa isidingo somoya-mpilo wemisipha yenhliziyo yakho, okusiza ukuvimbela izigameko zobuhlungu besifuba.

Lo muthi futhi usiza igazi ukuthi libuyele enhliziyweni yakho ngempumelelo enkulu, kunciphisa ingcindezi ngaphakathi emagumbini enhliziyo yakho. Le nzuzo ephindwe kabili yenza kube lula ukuthi inhliziyo yakho yenze umsebenzi wayo ngaphandle kokusebenza ngokweqile.

Kufanele Ngiyithathe Kanjani I-Isosorbide Dinitrate?

Thatha i-isosorbide dinitrate ngendlela eqondile udokotela wakho ayincomile, ngokuvamile esiswini esingenalutho ngengilazi yamanzi egcwele. Ukuyithatha nokudla kunganciphisa ukuthi umzimba wakho uyimunca ngokushesha kangakanani imithi.

Ngamaphilisi avamile, wagwinye wonke ngaphandle kokuwachoboza noma ukuwahlafuna. Uma usebenzisa amaphilisi akhishwe isikhathi eside, kubaluleke kakhulu ukungawaqhekezi, ngoba lokhu kungabangela ukuthi kukhishwe imithi eningi ngesikhathi esisodwa.

Ngamaphilisi angaphansi kolimi, uwabeke ngaphansi kolimi lwakho bese uwavumela ukuthi ancibilike ngokuphelele. Ungagwinyi, uhlafune, noma uphuze noma yini kuze kube yilapho ithebhulethi incibilike ngokugcwele. Lokhu kuvame ukuthatha imizuzu engaba ngu-1-3.

Zama ukuthatha imithi yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho. Uma udokotela wakho ekuqokele izilinganiso eziningi, zihlukanise ngokulinganayo usuku lonke njengoba kuqondisiwe.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Isosorbide Dinitrate?

Ubude besikhathi sokwelashwa nge-isosorbide dinitrate buhlukahluka kakhulu kuye ngesimo sakho somuntu ngamunye nokuphendula kwakho emuthini. Abanye abantu bayawudinga izinyanga ezimbalwa, kanti abanye bangawuthatha iminyaka eminingi njengengxenye yokunakekelwa kwenhliziyo okuqhubekayo.

Udokotela wakho uzoqapha njalo ukuthi umuthi usebenza kahle kangakanani kuwe nokuthi ngabe unazo yini izimo ezingezinhle. Bangase balungise umthamo wakho noma batusa izinguquko ngokuya ngezimpawu zakho kanye nempilo yenhliziyo yakho iyonke.

Ungayeki ukuthatha lo muthi kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe ngezinye izikhathi kungabangela umphumela wokubuyela emuva lapho ubuhlungu bakho besifuba buba bubi kakhulu okwesikhashana.

Yiziphi Izimo Ezingezinhle ze-Isosorbide Dinitrate?

Abantu abaningi bayawuthola kahle i-isosorbide dinitrate, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Imiphumela emibi evame kakhulu ivame ukuba mnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uyithole, ihlelwe ngokuthi ivela kaningi kangakanani:

Imiphumela Ejwayelekile Emibi

Le miphumela emibi yenzeka kubantu abaningi futhi ngokuvamile ayibi kakhulu:

• Ikhanda (ngokuvamile umphumela wokuqala omtholayo)
• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma
• Ukubomvu noma ukushisa ebusweni nasentanyeni yakho
• Isicanucanu noma isisu esibuhlungu
• Ubuthakathaka noma ukukhathala

Ikhanda livame ukuthuthuka ngemva kwezinsuku ezimbalwa noma amasonto njengoba umzimba wakho ujwayela umuthi. Udokotela wakho angase asikisele ukuqala ngomthamo ophansi ukuze unciphise lo mphumela.

Imiphumela Emibi Engavamile

Le miphumela emibi yenzeka kaningi kodwa kusabalulekile ukuyazi:

• Ukushaya kwenhliziyo okusheshayo noma ukushaya kwenhliziyo
• Ukubona okungacacile
• Umlomo owomile
• Ukujuluka
• Ukungazinzi noma ukukhathazeka

Uma ngabe iyiphi yale miphumela emibi iqhubeka noma iba yinkinga, yazisa udokotela wakho. Bangase bakwazi ukulungisa umthamo wakho noma isikhathi sokusiza ukunciphisa.

Imiphumela emibi kodwa ebucayi

Nakuba kungavamile, le miphumela emibi idinga ukunakekelwa kwezokwelapha ngokushesha:

• Ukwehla okukhulu kwengcindezi yegazi okubangela ukuquleka
• Ukuphendula komzimba ngokuqubuka, ukuluma, noma ukuvuvukala
• Ikhanda elibuhlungu eliqhubekayo elibuhlungu
• Ubuhlungu besifuba obuba bukhulu noma obushintsha ngesimo
• Ukuphefumula kanzima noma ukuphefumula ngokushesha

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi zalezi zimpawu. Zingase zikhombe ukuthi umuthi awukulungele noma ukuthi umthamo wakho udinga ukulungiswa.

Ubani Ongafanele Athathe I-Isosorbide Dinitrate?

Abantu abathile akufanele bathathe i-isosorbide dinitrate ngoba ingaba yingozi empilweni yabo. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuchazela lo muthi.

Akufanele uthathe lo muthi uma une-anemia ebucayi, njengoba ingenza lesi simo sibe sibi kakhulu. Abantu abanezinhlobo ezithile zezifo zenhliziyo, njenge-hypertrophic cardiomyopathy, bangase badinge nokugwema lo muthi.

Uma uthatha imithi yokwelapha ukungasebenzi kahle kwesitho sangasese (njenge-sildenafil, tadalafil, noma vardenafil), awukwazi ukuthatha i-isosorbide dinitrate. Inhlanganisela ingabangela ukwehla okuyingozi kwengcindezi yegazi okungase kube yingozi empilweni.

Abantu abanengcindezi yegazi ephansi kakhulu, izinhlobo ezithile ze-glaucoma, noma labo abaye balimala ekhanda muva nje kufanele futhi bagweme lo muthi. Hlala utshela udokotela wakho ngayo yonke imithi kanye nezithasiselo ozithathayo.

Amagama Omkhiqizo we-Isosorbide Dinitrate

I-Isosorbide dinitrate itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Isordil ingelinye elaziwa kakhulu. Ungase futhi ukubone kuthengiswa njenge-Dilatrate-SR ngenguqulo yokukhishwa okwandisiwe.

Izinhlobo ezivamile zitholakala kabanzi futhi zisebenza ngempumelelo njengezinhlobo zegama lomkhiqizo. Umkhemisi wakho angakusiza ukuthi uqonde ukuthi iyiphi ifomu olitholayo futhi aqinisekise ukuthi ulithatha ngendlela efanele.

Noma ngabe uthola uhlobo oluqanjwe ngegama lomkhiqizo noma oluvamile ngokuvamile kuncike ekuhlinzekweni komshuwalense wakho kanye nokutholakala kwemithi ekhemisi. Zombili ziphephile futhi ziyasebenza ngokulinganayo uma zisetshenziswa njengoba kunqunywe.

Ezinye Izindlela Zokwelapha ze-Isosorbide Dinitrate

Uma i-isosorbide dinitrate ingasebenzi kahle kuwe noma ibangela imiphumela emibi, udokotela wakho unezinye izindlela zokwelapha okufanele azicabangele. Ezinye izinhlobo ze-nitrates njenge-isosorbide mononitrate noma i-nitroglycerin zisebenza ngendlela efanayo kodwa zingase zibekezelelwe kangcono ngabanye abantu.

Ezinye izindlela ezingezona ze-nitrate zihlanganisa ama-calcium channel blockers afana ne-amlodipine noma i-diltiazem, nawo asiza ekuphumuleni kwemithambo yegazi. Ama-beta-blockers afana ne-metoprolol anganciphisa umsebenzi wenhliziyo yakho ngendlela ehlukile.

Udokotela wakho angase futhi acabangele imithi emisha efana ne-ranolazine, esebenza ngendlela ehlukile ukusiza ekuvikeleni ubuhlungu besifuba. Enye indlela engcono kakhulu incike esimweni sakho esithile, eminye imithi oyithathayo, nokuthi usabela kanjani ekwelashweni.

Ingabe i-Isosorbide Dinitrate Ingcono Kune-Nitroglycerin?

Kokubili i-isosorbide dinitrate ne-nitroglycerin ziyimithi ye-nitrate esebenzayo, kodwa zisebenza kangcono ezimweni ezehlukene. I-Nitroglycerin isebenza ngokushesha, okuyenza ilungele ukukhululeka ngokushesha ngesikhathi sokuhlaselwa kobuhlungu besifuba.

I-Isosorbide dinitrate ihlala isikhathi eside ohlelweni lwakho, okuyenza ibe ngcono ekuvikeleni ubuhlungu besifuba usuku lonke. Abantu abaningi basebenzisa zombili le mithi ndawonye - i-nitroglycerin ukuze bathole ukukhululeka okusheshayo kanye ne-isosorbide dinitrate ukuze bavikeleke ngokuqhubekayo.

Udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe ezidingweni zakho ezithile, iphethini yobuhlungu besifuba sakho, nokuthi uyibekezelela kangakanani imithi ngayinye. Abanye abantu benza ngcono ngomunye kunomunye, kanti abanye bayazuza ekusebenziseni zombili.

Imibuzo Evame Ukubuzwa Mayelana ne-Isosorbide Dinitrate

Q1. Ingabe i-Isosorbide Dinitrate Iphephile Kubantu Abanesifo Sikashukela?

Yebo, i-isosorbide dinitrate ngokuvamile iphephile kubantu abanesifo sikashukela. Ayithinti ngokuqondile amazinga kashukela egazini, ngakho ngeke iphazamise ukuphathwa kwesifo sakho sikashukela.

Kodwa-ke, uma unesifo senhliziyo esihlobene nesifo sikashukela, udokotela wakho uzokuhlola eduze uma uqala lo muthi. Ukuhlanganiswa kwesifo sikashukela nesifo senhliziyo kudinga ukuphathwa ngokucophelela kwawo wonke amakhambi.

Umbuzo 2. Kufanele ngenzeni uma ngithatha i-Isosorbide Dinitrate eningi ngengozi?

Uma ngengozi uthatha i-isosorbide dinitrate eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Izimpawu zokweqisa umthamo zihlanganisa ikhanda elibuhlungu elibukhali, isiyezi, ukushaya kwenhliziyo okusheshayo, isicanucanu, nokuphelelwa amandla.

Ungazami ukuzenza uhlanze. Kunalokho, hlala phansi noma ulale phansi ukuze uvimbele ukuwa uma uzizwa unesiyezi. Uma uphelelwa amandla noma unzima ukuphefumula, shayela izinsiza eziphuthumayo ngokushesha.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Isosorbide Dinitrate?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma usebenzise umhleli wamaphilisi. Ukuthatha imithi ngokuqhubekayo kubalulekile ekuvikeleni izigameko zobuhlungu besifuba ngempumelelo.

Umbuzo 4. Ngingayeka nini ukuthatha i-Isosorbide Dinitrate?

Yeka kuphela ukuthatha i-isosorbide dinitrate uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Noma ngabe uzizwa ungcono, isimo senhliziyo yakho esingaphansi kungenzeka sisadinga ukwelashwa.

Udokotela wakho anganciphisa kancane umthamo wakho ngaphambi kokuyeka ngokuphelele ukuvimbela noma yibuphi ubuhlungu besifuba obubuyayo. Ukuqokwa okuvamile kokulandela ngemuva kusiza ukunquma isikhathi esifanele sokulungisa noma ukuyeka imithi yakho.

Umbuzo 5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Isosorbide Dinitrate?

Kufanele ukhawulele ukusetshenziswa kotshwala ngenkathi uthatha i-isosorbide dinitrate, ngoba kokubili kunganciphisa umfutho wegazi lakho. Ukuphuza utshwala kungandisa ingozi yakho yesiyezi, ukuphelelwa amandla, nokuwa.

Uma ukhetha ukuphuza, kwenze ngokulinganisela futhi uqaphele kakhulu uma usukuma noma ushintsha izikhundla. Khuluma nodokotela wakho ngobuningi botshwala, uma bukhona, obuphephile kuwe.