Yini i-Isosorbide Mononitrate: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Isosorbide mononitrate ngumuthi wenhliziyo osiza ekuvikeleni ubuhlungu besifuba (i-angina) ngokuthuthukisa ukuhamba kwegazi enhliziyweni yakho. Iyingxenye yeqembu lemithi ebizwa ngokuthi ama-nitrate asebenza ngokuphumuza nokwandisa imithambo yakho yegazi, okwenza kube lula enhliziyweni yakho ukuthola umoya-mpilo ewudingayo.

Lo muthi uvame ukunqunyelwa abantu abanezifo zemithambo yenhliziyo ababa nobuhlungu besifuba ngesikhathi sokuzivocavoca noma ukucindezeleka. Udokotela wakho angase akuphakamise njengengxenye yohlelo lokwelapha olubanzi ukukusiza ukuthi uzizwe ukhululekile futhi uhlale usebenza.

Yini i-Isosorbide Mononitrate Esetshenziselwa Yona?

I-Isosorbide mononitrate ikakhulukazi ivimbela ukuhlaselwa yi-angina, okuyizigameko zobuhlungu besifuba ezenzeka lapho imisipha yenhliziyo yakho ingatholi umoya-mpilo owanele. Cabanga ngayo njengokugcina izindlela zenhliziyo yakho zihlanzekile futhi zivulekile ukuze igazi ligeleze kalula.

Ngokuvamile, odokotela banquma lo muthi we-chronic stable angina. Lokhu kusho ukuthi uba nobuhlungu besifuba obuqagelwayo ngesikhathi semisebenzi efana nokuhamba phezulu, ukuzivocavoca, noma ngezikhathi ezicindezelayo. Umuthi usebenza ngokuvimbela, unciphisa ukuthi lezi zigameko ezibuhlungu zenzeka kangaki.

Kwezinye izimo, udokotela wakho angase akuqokele ukuhluleka kwenhliziyo njengokwelashwa okwengeziwe. Lokhu kwenzeka lapho inhliziyo yakho idinga ukwesekwa okwengeziwe ekuphumpeni igazi ngempumelelo emzimbeni wakho wonke. Umuthi usiza ukunciphisa umsebenzi wenhliziyo yakho ngokwenza imithambo yegazi iguquguquke kakhulu.

Isebenza Kanjani i-Isosorbide Mononitrate?

I-Isosorbide mononitrate ingeyeqembu lemithi yenhliziyo enamandla aphakathi nendawo esebenza ngokukhipha i-nitric oxide emithanjeni yakho yegazi. Lolu phawu lwekhemikhali yemvelo lutshela imithambo yakho yegazi ukuthi iphumule futhi yande, kufana nendlela ipayipi lengadi elivuleka ngayo lapho ukhulula ingcindezi.

Lapho imithambo yakho yegazi yanda, inhliziyo yakho akudingeki isebenze kanzima ukuze ipompe igazi ngayo. Lokhu kunciphisa isidingo somoya-mpilo emsipheni wenhliziyo yakho futhi kusiza ekuvikeleni ubuhlungu besifuba obenzeka lapho inhliziyo yakho ilwela ukuthola umoya-mpilo owanele.

Umuthi usebenza kancane kancane emahoreni amaningana, unikeza ukuvikeleka okuqhubekayo usuku lonke. Ngokungafani neminye imithi yenhliziyo esebenza ngokushesha, le nto igxila ekuvikeleni isikhathi eside kunokukhulula izimpawu ngokushesha.

Kufanele Ngiyithathe Kanjani I-Isosorbide Mononitrate?

Thatha i-isosorbide mononitrate ngendlela eqondile udokotela wakho ayincomile, ngokuvamile kanye ngosuku ekuseni. Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele, futhi ungayichobozi, uyihlafune, noma uyihlukanise ngoba lokhu kungathinta indlela umuthi okhishwa ngayo emzimbeni wakho.

Ungawuthatha lo muthi ngaphandle noma ngaphandle kokudla, kodwa zama ukungaguquguquki ngohlelo lwakho. Uma uzwa isisu esibuhlungu, ukuwuthatha ngokudla okulula noma ukudla okulula kungasiza. Gwema ukuwuthatha ngokudla okunamafutha amaningi, ngoba lokhu ngezinye izikhathi kungathinta ukuthi umzimba wakho uwumunca kahle kangakanani umuthi.

Kubalulekile ukuthatha umthamo wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emgudwini wakho wegazi. Ukusetha isikhumbuzi sansuku zonke ocingweni lwakho noma ukuwuthatha nenye inqubo yansuku zonke, njengokuxubha amazinyo akho, kungakusiza ukuthi ukhumbule.

Ungayeki ukuthatha lo muthi ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Umzimba wakho udinga isikhathi sokuzivumelanisa, futhi ukuyeka kungazelelwe kungase kubangele ukuthi ubuhlungu bakho besifuba bubuye noma buqhubeke.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Isosorbide Mononitrate?

Abantu abaningi bathatha i-isosorbide mononitrate izinyanga noma iminyaka njengengxenye yokuphathwa kwempilo yabo yenhliziyo yesikhathi eside. Ubude besikhathi buxhomeke esimweni sakho senhliziyo esithile nokuthi usabela kahle kangakanani ekwelashweni.

Udktela wakho uzohlola njalo ukuthi umuthi usebenza kahle kangakanani kuwe ngokuqokwa okulandelayo kanye nokuhlolwa kwenhliziyo okungenzeka. Bazobheka izinto ezinjengokuthi uvame kangakanani ukuzwa ubuhlungu besifuba, izinga lakho lomsebenzi, nanoma yimaphi imiphumela emibi ongase ube nayo.

Abanye abantu bangase badinge ukuthatha lo muthi impilo yabo yonke, ikakhulukazi uma benesifo semithambo yenhliziyo esiqhubekayo. Abanye bangase bakwazi ukunciphisa umthamo wabo noma bayeke umuthi uma isimo senhliziyo yabo sithuthuka kakhulu ngezinguquko zokuphila kanye neminye imithi.

Yini Imiphumela Eceleni ye-Isosorbide Mononitrate?

Njengayo yonke imithi, i-isosorbide mononitrate ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Imiphumela emibi evame kakhulu ivame ukuba mncane futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uyithole, futhi kuyasiza ukwazi okulindelekile ukuze ukwazi ukuxoxa nganoma yiziphi izinkathazo nomhlinzeki wakho wezempilo:

• Ukucabuka kwekhanda - Lena imiphumela emibi evame kakhulu, ethinta cishe abantu abangu-3 kwabangu-4 ekuqaleni. Ukucabuka kwekhanda kuvame ukuba ngaphansi ngemva kwamasonto ambalwa okwelashwa.
• Isiyezi noma ukukhathala - Lokhu kwenzeka ngoba umuthi wehlisa umfutho wegazi lakho. Ngokuvamile kuqashelwa kakhulu uma usukuma ngokushesha.
• Ukubomvu noma ukufudumala - Ungase uzizwe ufudumele noma uqaphele ukuthi isikhumba sakho sibomvu, ikakhulukazi ebusweni nasentanyeni yakho.
• Isicanucanu - Abanye abantu bazwa isisu esincane esicasulayo, ikakhulukazi lapho beqala umuthi.
• Ukukhathala - Ungase uzizwe ukhathele kunokujwayelekile, ikakhulukazi ngesikhathi samasonto ambalwa okuqala okwelashwa.

Le miphumela emibi evamile ivame ukuzinza phakathi kwamasonto angu-2-4 njengoba umzimba wakho uzivumela emuthini. Uma ziqhubeka noma ziba yinkinga, udokotela wakho uvame ukulungisa umthamo wakho noma isikhathi.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukuqaphela:

• Ukwehla okukhulu kwengcindezi yegazi - Izimpawu zihlanganisa isiyezi esikhulu, ukuquleka, noma ukuzizwa sengathi ungaquleka
• Ukushaya kwenhliziyo okungajwayelekile - Inhliziyo yakho ingase izizwe sengathi iyagijima, yeqe ukushaya, noma ishaya ngendlela engavamile
• Ukuphendula komzimba okukhulu - Lokhu kuhlanganisa ubunzima bokuphefumula, ukuvuvukala kobuso bakho noma umphimbo, noma ukuqubuka okukhulu
• Ubuhlungu besifuba obuba bubi kakhulu - Uma i-angina yakho iba njalo noma ibe nkulu nakuba usebenzisa imithi

Uma uhlangabezana nanoma yimiphi yale miphumela emibi ebucayi, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezempilo eziphuthumayo. Khumbula, lezi zimo ezinzima azivamile, kodwa ukwazi ukuthi yini okufanele uyibheke kusiza ukukugcina uphephile.

Obani okungafanele basebenzise i-Isosorbide Mononitrate?

Abantu abathile kufanele bagweme i-isosorbide mononitrate ngoba ingaba yingozi noma ingasebenzi kahle ezimweni zabo zezempilo ezithile. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela le mithi.

Akufanele usebenzise i-isosorbide mononitrate uma une-anemia ebucayi, njengoba igazi lakho selivele linobunzima bokuthwala umoya-mpilo ezicutshini zakho. Umuthi ungenza lesi simo sibe sibi ngokwehlisa ingcindezi yakho yegazi kakhulu.

Abantu abanezimo ezithile zenhliziyo nabo kufanele bagweme le mithi. Uma une-hypertrophic cardiomyopathy (isimo lapho imisipha yenhliziyo yakho iqina ngokungavamile), umuthi ungase wenze izimpawu zakho zibe zimbi kunokuba zibe ngcono.

Nansi ezinye izimo ezibalulekile lapho le mithi ingase ingakulungele:

• Isifo esibi sezinso - Izinso zakho zingase zingakwazi ukucubungula imithi kahle
• Isifo esibi sesibindi - Isibindi sakho sidinga ukwehlisa imithi, futhi izinkinga ezinkulu zesibindi zingaphazamisa le nqubo
• Umfutho wegazi ophansi kakhulu - Umuthi ungenza umfutho wegazi wehle nakakhulu, okungaba yingozi
• Ukuphazamiseka kwekhanda kwamuva - Umuthi ungakhuphula ingcindezi ekhakhazini lakho
• Izimo ezithile zamehlo - Ikakhulukazi ukwanda kwengcindezi emehlweni (i-glaucoma)

Ngaphezu kwalokho, uma uthatha imithi yokungasebenzi kahle kwe-erectile njenge-sildenafil (Viagra), i-tadalafil (Cialis), noma i-vardenafil (Levitra), awukwazi ukuthatha i-isosorbide mononitrate. Le nhlanganisela ingabangela ukwehla okuyingozi komfutho wegazi.

Njalo tshela udokotela wakho ngayo yonke imithi, izithasiselo, kanye nezimo zempilo onazo. Lokhu kubasiza ukuthi banqume ukuthi i-isosorbide mononitrate iphephile futhi ifanele isimo sakho esithile.

Amagama Omkhiqizo we-Isosorbide Mononitrate

I-Isosorbide mononitrate itholakala ngaphansi kwamagama amaningana omkhiqizo, nakuba inguqulo ejwayelekile isebenza ngempumelelo. Amagama omkhiqizo ajwayelekile afaka i-Imdur, i-Ismo, ne-Monoket.

I-Imdur cishe igama lomkhiqizo elaziwa kakhulu futhi iza ngamaphilisi akhishwe isikhathi eside owathatha kanye ngosuku. I-Ismo ne-Monoket nazo ziyatholakala futhi zisebenza ngezindlela ezifanayo, nakuba zingase zibe namaphethini ahlukile okukhishwa.

Ikhemisi lakho lingase lithathe indawo yenguqulo ejwayelekile yegama lomkhiqizo ngaphandle uma udokotela wakho ebhala ngqo ukuthi "igama lomkhiqizo kuphela" emiyalelweni yakho. Inguqulo ejwayelekile iqukethe isithako esifanayo esisebenzayo futhi isebenza ngokufana nezinguqulo zegama lomkhiqizo.

Ezinye izindlela ze-Isosorbide Mononitrate

Uma i-isosorbide mononitrate ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, udokotela wakho unezinye izinketho eziningi zokukusiza ukulawula i-angina yakho. Ngasinye isinye sezindlela sisebenza ngendlela ehlukile, ngakho-ke ukuthola esifanele ngokuvamile kuncike esimweni sakho senhliziyo esithile kanye nempilo yakho yonke.

Ama-beta-blockers afana ne-metoprolol noma i-atenolol ayizindlela ezivamile ezinciphisa izinga lokushaya kwenhliziyo yakho futhi anciphise ukuthi inhliziyo yakho isebenza kanzima kangakanani. Le mithi ingaba usizo ikakhulukazi uma futhi unomfutho wegazi ophezulu noma wake wahlaselwa yinhliziyo.

Ama-calcium channel blockers afana ne-amlodipine noma i-diltiazem anikeza enye indlela ngokukhulula imithambo yegazi futhi anciphise umsebenzi wenhliziyo yakho. Lokhu kungase kukhethwe uma unezinhlobo ezithile ze-angina noma uma ungaqedi ama-nitrates.

Nazi ezinye izindlela ezingase zicatshangelwe udokotela wakho:

• Isosorbide dinitrate - Umuthi ofanayo we-nitrate owuthatha izikhathi eziningi ngosuku esikhundleni sokuthatha kanye ngosuku
• Ranolazine - Umuthi omusha osebenza ngendlela ehlukile kuma-nitrates futhi onganezelwa ekwelashweni kwakho kwamanje
• Izithambiso ze-Nitroglycerin - Lezi zinikeza imithi eqhubekayo ngesikhumba sakho usuku lonke
• Ama-ACE inhibitors - Lokhu kuyasiza uma futhi unenhliziyo ehlulekayo noma umfutho wegazi ophezulu kanye ne-angina

Udokotela wakho uzosebenza nawe ukuthola enye indlela engcono kakhulu esekelwe ezimpawini zakho, ezinye izimo zempilo, nokuthi uzithatha kanjani kahle imithi ehlukene. Ngezinye izikhathi inhlanganisela yemithi isebenza kangcono kunanoma iyiphi eyodwa yodwa.

Ingabe i-Isosorbide Mononitrate Ingcono Kune-Nitroglycerin?

I-Isosorbide mononitrate kanye ne-nitroglycerin zisebenzela izinjongo ezihlukene ekwelapheni ubuhlungu besifuba, ngakho-ke ukuziqhathanisa kufana nokuqhathanisa ivithamini yansuku zonke nomuthi wokudambisa ubuhlungu. Zombili zibalulekile, kodwa zisebenza ngezindlela ezihlukene nangezikhathi ezihlukene.

I-isosorbide mononitrate yenzelwe ukuvimbela isikhathi eside sokuhlaselwa kwe-angina. Uyithatha kanye ngosuku ukuze ugcine imithambo yakho yegazi iphumule usuku lonke, okunciphisa amathuba okuthi ubuhlungu besifuba buvele.

Ngakolunye uhlangothi, i-Nitroglycerin isebenza ngokushesha ukumisa ubuhlungu besifuba obuvele bukhona. Ubeka ithebhulethi ngaphansi kolimi lwakho noma usebenzise isifutho lapho uzwa ubuhlungu besifuba buqala, futhi ngokuvamile isebenza ngemizuzu engu-1-3.

Abantu abaningi empeleni basebenzisa yomibili imithi ndawonye njengengxenye yohlelo lwabo lokwelapha. I-isosorbide mononitrate isebenza njengokuvimbela kwakho kwansuku zonke, kuyilapho i-nitroglycerin isebenza njengomuthi wakho wokusiza ekuhlaselweni kobuhlungu besifuba.

Udokotela wakho uzokusiza ukuthi uqonde ukuthi iyiphi indlela engcono kakhulu esimweni sakho esithile. Abanye abantu benza kahle ngomuthi owodwa nje, kanti abanye bayazuza ekubeni nokwelashwa kokuvimbela nokusiza okutholakalayo.

Imibuzo Evame Ukubuzwa Mayelana ne-Isosorbide Mononitrate

Ingabe i-Isosorbide Mononitrate iphephile kubantu abanesifo sikashukela?

Yebo, i-isosorbide mononitrate ngokuvamile iphephile kubantu abanesifo sikashukela futhi ayithinti ngokuqondile amazinga kashukela egazini. Kodwa-ke, uma unesifo sikashukela, usengozini enkulu yokugula kwenhliziyo, ngakho udokotela wakho uzokuqapha eduze.

Umuthi ungase uhlangane nezinye izinkinga zesifo sikashukela, ikakhulukazi uma une-diabetic nerve damage ethinta ukulawulwa kwengcindezi yakho yegazi. Udokotela wakho uzokucabangela lokhu lapho ekunikeza umthamo wakho futhi eqapha ukusabela kwakho ekwelashweni.

Ngingenzani uma ngiphuthelwa ngengozi ngithatha i-Isosorbide Mononitrate eningi kakhulu?

Uma ngengozi uthatha okuningi kunomthamo wakho obekiwe, xhumana nodokotela wakho noma ukulawulwa kwezinto ezinobuthi ngokushesha, ngisho noma uzizwa ulungile. Ukuthatha okuningi kungabangela ukwehla okuyingozi kwengcindezi yegazi, ikhanda elibuhlungu eliqinile, noma ukuquleka.

Ngesikhathi ulindele iseluleko sezokwelapha, lala phansi izinyawo zakho ziphakanyisiwe futhi gwema ukunyakaza okungazelelwe. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo. Gcina ibhodlela lemithi nawe ukuze ukwazi ukubatshela ngqo ukuthi uthathe malini.

Kufanele Ngenzeni Uma Ngeqe Umthamo We-Isosorbide Mononitrate?

Uma ugeqa umthamo wakho wasekuseni, uyithathe ngokushesha nje lapho ukhumbula, ngaphandle uma sekuhlwile. Uma sekudlule emini ntambama, weqa umthamo oqediwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile ekuseni ngakusasa.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo oqediwe, ngoba lokhu kungabangela ukuthi umfutho wegazi lakho wehle kakhulu. Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma ukugcina imithi yakho endaweni ozoyibona lapho wenza umsebenzi wakho wasekuseni.

Ngingayeka Nini Ukuthatha I-Isosorbide Mononitrate?

Misa kuphela ukuthatha i-isosorbide mononitrate uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Noma ngabe uzizwa ungcono futhi awuzange ube nobuhlungu besifuba isikhashana, imithi ingase ivimbele izimpawu ukuthi zingabuyi.

Udokotela wakho ngokuvamile uzofuna ukubona ukuthi wenza kanjani ngokuhlolwa okuvamile futhi mhlawumbe nokuhlolwa kwenhliziyo ngaphambi kokunquma ukuthi ungalinciphisa ngokuphepha noma uyeke imithi. Bazokwenza uhlelo oluqhubekayo lokwehlisa umthamo wakho kancane uma ukuyeka kufanelekile.

Ngingakwazi Yini Ukuphuza Utshwala Ngenkathi Ngithatha I-Isosorbide Mononitrate?

Kufanele unciphise ukusetshenziswa kotshwala ngenkathi uthatha i-isosorbide mononitrate ngoba kokubili utshwala kanye nemithi kunganciphisa umfutho wegazi lakho. Uma kuhlanganiswe, kungase kubangele isiyezi esikhulu, ukuquleka, noma ukuwa.

Uma ukhetha ukuphuza utshwala, kwenze ngokulinganisela futhi uqaphele kakhulu lapho usukuma noma ushintsha izikhundla. Khuluma nodokotela wakho mayelana nokuthi yiluphi utshwala, uma bukhona, obuphephile kuwe ngokusekelwe empilweni yakho yonke neminye imithi oyithathayo.