Yini i-Labetalol (Indlela Yokungenisa Ngemithambo): Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Labetalol intravenous (IV) iyimithi kadokotela abayisebenzisela ukwehlisa ngokushesha umfutho wegazi ophezulu ngokuyingozi ezindaweni zasezibhedlela. Kuyimithi yomfutho wegazi esebenza kabili esebenza ngokuvimba zombili izamukeli ze-alpha ne-beta enhliziyweni yakho nasemithanjeni yegazi, okusiza ukuba ziphumule futhi zinciphise umfutho ohlelweni lwakho lwe-cardiovascular.

Le mithi yenzelwe ngqo izimo eziphuthumayo lapho umfutho wakho wegazi udinga ukwehla ngokushesha kodwa ngokuphepha. Ngokungafani namaphilisi omfutho wegazi ongawathatha ekhaya, i-IV labetalol isebenza ngemizuzu futhi inikeza abahlinzeki bezempilo ukulawula okunembile ngendlela umfutho wakho wegazi osabela ngayo ekwelashweni.

Yini i-Labetalol IV Esetshenziselwa Yona?

I-Labetalol IV isetshenziselwa ikakhulukazi ukwelapha izimo eziphuthumayo ze-hypertensive kanye nomfutho wegazi ophezulu ongathi sína odinga ukunakekelwa kwezokwelapha ngokushesha. Lezi yizimo lapho umfutho wakho wegazi usufinyelele emazingeni angalimaza izitho zakho uma zingelashwa ngokushesha.

Odokotela bavame ukusebenzisa le mithi lapho umfutho wakho wegazi we-systolic (inombolo ephezulu) ingaphezu kuka-180 mmHg noma umfutho wakho we-diastolic (inombolo engezansi) ingaphezu kuka-120 mmHg, futhi uhlangabezana nezimpawu noma usengozini yezinkinga. Ivame futhi ukusetshenziswa ngesikhathi nangemva kokuhlinzwa okuthile ukuze kugcinwe umfutho wegazi uzinzile lapho ukhuphuka ngokungalindelekile.

Abahlinzeki bezempilo bangakhetha i-labetalol IV kwabesifazane abakhulelwe abanomfutho wegazi ophezulu ongathi sína ohlobene nokukhulelwa (i-preeclampsia) ngoba ithathwa njengephephile kokubili umama nengane uma iqhathaniswa neminye imithi ephuthumayo yomfutho wegazi. Imithi isiza ukuvimbela izinkinga eziyingozi njengokuqina kwegazi, ukuhlaselwa yinhliziyo, noma ukulimala kwezinso okungenzeka uma umfutho wegazi uhlala uphakeme kakhulu.

Isebenza Kanjani i-Labetalol IV?

I-Labetalol IV isebenza ngokuvimba izinhlobo ezimbili ezihlukene zama-receptors emzimbeni wakho - ama-alpha receptors nama-beta receptors. Cabanga ngala ma-receptors njengama-switch alawula ukuthi inhliziyo yakho ishaya kanjani nokuthi imithambo yakho yegazi iminyene kangakanani.

Uma i-labetalol ivimba ama-beta receptors enhliziyweni yakho, yehlisa izinga lokushaya kwenhliziyo yakho futhi inciphise indlela inhliziyo yakho eshisa ngayo. Ngesikhathi esifanayo, ivimba ama-alpha receptors emithanjeni yakho yegazi, okubangela ukuthi aphumule futhi ande. Lesi senzo esiphindwe kabili sidala ukwehla okubushelelezi, okulawulwayo ekucindezelweni kwegazi.

Lo muthi uthathwa njengomuthi onamandla ngokulinganisela - unamandla ngokwanele ukubhekana nezimo eziphuthumayo zokucindezelwa kwegazi kodwa uthambile ngokwanele ukugwema ukubangela ukuthi ukucindezelwa kwegazi lakho lehle ngokushesha kakhulu, okungaba yingozi. Ifomu le-IV livumela odokotela ukuthi babone imiphumela phakathi kwemizuzu emi-2-5 futhi balungise umthamo njengoba kudingeka ukuze kuzuzwe izinga elifanele lokucindezelwa kwegazi lesimo sakho esithile.

Ngingayithola Kanjani I-Labetalol IV?

I-Labetalol IV inikezwa njalo ochwepheshe bezempilo abaqeqeshiwe esibhedlela noma endaweni yezokwelapha - ngeke nanini ukhathazeke ngokuzinika lo muthi wena uqobo. Ithimba lezokwelapha lizofaka ipayipi elincane (i-IV catheter) emthanjeni engalweni yakho bese linikeza umuthi ngqo emgudwini wakho wegazi.

Umhlinzeki wakho wezempilo uzokuqapha eduze kuyo yonke inqubo, ehlola ukucindezelwa kwegazi lakho njalo ngemizuzu embalwa futhi ebuka noma yiziphi izinguquko endleleni ozizwa ngayo. Bangase bakunikeze umuthi njengesitsha esisodwa noma njengokuthontsa okuqhubekayo, kuye ngokuthi ukucindezelwa kwegazi lakho kuphendula kanjani.

Akudingeki ukuthi wenze lutho olukhethekile ukulungiselela lo muthi - akukho ukuzila ukudla noma ukudla okukhethekile okudingekayo. Kodwa-ke, kubalulekile ukutshela ithimba lakho lezempilo nganoma yimiphi eminye imithi oyithathayo, okuhlanganisa imithi etholakala ngaphandle kwe-oda kanye nezithasiselo, ngoba lezi zingathinta indlela i-labetalol esebenza ngayo emzimbeni wakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Labetalol IV?

Isikhathi sokwelashwa nge-labetalol IV sincike ngokuphelele esimweni sakho somuntu ngamunye nokuthi umfutho wakho wegazi usabela kanjani emuthini. Abantu abaningi bathola lo muthi isikhathi esifushane - noma yikuphi kusuka emahoreni ambalwa kuya ezinsukwini ezimbalwa.

Ithimba lakho lezempilo lizoqhubeka nokuhlola umfutho wakho wegazi futhi lehlise kancane umuthi we-IV njengoba isimo sakho sizinzile. Uma umfutho wakho wegazi ulawulwa futhi uzinzile, udokotela wakho cishe uzokushintshela emithini yomfutho wegazi yomlomo ongayithatha ekhaya.

Abanye abantu bangase badinge i-labetalol IV izinsuku eziningana uma belulama ngemva kokuhlinzwa noma uma umfutho wabo wegazi uthatha isikhathi ukuzinza. Ithimba lakho lezokwelapha lizokwenza lezi zinqumo ngokusekelwe ezidingweni zakho zempilo ezithile nokuthi usabela kahle kangakanani ekwelashweni.

Yiziphi Imiphumela Eceleni ye-Labetalol IV?

Njengayo yonke imithi, i-labetalol IV ingabangela imiphumela emibi, nakuba abantu abaningi behlangabezana nezinkinga ezimbalwa noma ezingekho. Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uhlangabezane nayo, ukhumbula ukuthi ithimba lakho lezempilo likuhlola ngokusondele futhi lingaxazulula noma yikuphi ukukhathazeka ngokushesha:

• Isiyezi noma ukuzizwa unovalo, ikakhulukazi uma ushintsha izikhundla
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Isicanucanu noma isisu esincane
• Ukuzwa ukuluma ekhanda lakho noma esikhumbeni
• Ikhanda elincane
• Umuzwa wokufudumala noma ukubomvu

Le miphumela emibi evamile ngokuvamile iyazixazulula yodwa futhi akuvamile ukuthi idinge ukuyeka umuthi. Ithimba lakho lezempilo liyazi ukuthi lingayiphatha kanjani le miphumela futhi lizokusiza ukuthi uzizwe ukhululekile ngangokunokwenzeka.

Imiphumela emibi engathi sína ayivamile kodwa idinga ukunakekelwa kwezokwelapha ngokushesha. Njengoba usuvele usesimweni sokunakekelwa kwezempilo, ithimba lakho lezokwelapha lizobona ngokushesha futhi liphathe noma yiziphi izimpawu ezikhathazayo:

• Ukwehla okukhulu kwengcindezi yegazi okubangela ubuthakathaka noma ukuquleka
• Ukuphefumula kanzima noma ukukhwehlela
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile
• Isiyezi esikhulu esingathuthuki ngokulala phansi
• Izimpawu zokungezwani komzimba nezinto ezithile njengokuqubuka, ukuluma, noma ukuvuvukala

Imiphumela emibi engavamile kodwa engathi sína ingabandakanya izinkinga zesibindi noma ukungezwani komzimba okukhulu, kodwa lokhu kwenzeka ngaphansi kuka-1% weziguli. Ithimba lakho lokunakekelwa kwezempilo liqeqeshwe ukubona lezi zinkinga ezingavamile kusenesikhathi futhi liphendule ngendlela efanele.

Ubani Ongafanele Athole I-Labetalol IV?

I-Labetalol IV ayifanele wonke umuntu, futhi ithimba lakho lokunakekelwa kwezempilo lizobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukunika lo muthi. Kunezimo eziningana ezenza lo muthi ungaphephile noma ungasebenzi kahle.

Akufanele uthole i-labetalol IV uma unezimo ezithile zenhliziyo ezingase zibe zimbi ngenxa yemiphumela yomuthi ekushayeni kwenhliziyo yakho nesigqi:

• Ukuhluleka kwenhliziyo okukhulu noma ukushaqeka kwe-cardiogenic
• Ukuvinjelwa kwenhliziyo kwesibili noma kwesithathu ngaphandle kwe-pacemaker
• Isifuba esikhulu noma isifo esingamahlalakhona sokuvinjelwa kwamaphaphu (COPD)
• Ukungezwani okwaziwayo ne-labetalol noma imithi efanayo
• Isifo sesibindi esibi noma ukuhluleka kwesibindi
• Izinhlobo ezithile zokuphazamiseka kwesigqi senhliziyo

Udokotela wakho uzosebenzisa ukuqapha okwengeziwe uma unesifo sikashukela, izinkinga ze-thyroid, noma izinkinga zezinso, njengoba i-labetalol ingathinta indlela lezi zimo eziphathwa ngayo. Umuthi ungase ufihle ezinye izimpawu zikashukela ophansi egazini kubantu abanesifo sikashukela, ngakho-ke ithimba lakho lokunakekelwa kwezempilo lizokuqapha eduze.

Uma ukhulelwe noma uncelisa, udokotela wakho uzohlola ngokucophelela izinzuzo nezingozi, nakuba i-labetalol ivame ukubhekwa njengenye yezinketho eziphephe kakhulu zokwelapha umfutho wegazi ophezulu ngesikhathi sokukhulelwa.

Amagama Omkhiqizo we-Labetalol IV

I-Labetalol IV itholakala ngaphansi kwamagama amaningi emikhiqizo, nakuba izibhedlela eziningi zisebenzisa inguqulo ejwayelekile. Igama lomkhiqizo elivamile ongase ulizwe yi-Trandate, okuyigama lomkhiqizo wokuqala le-labetalol.

Amanye amagama emikhiqizo afaka i-Normodyne, nakuba lokhu kungasetshenziswa kakhulu namuhla. Izikhungo eziningi zokunakekelwa kwezempilo zigcina inguqulo ejwayelekile ye-labetalol IV ngoba isebenza kahle ngokulinganayo futhi ishibhile kunezinguqulo zamagama emikhiqizo.

Kungakhathaliseki ukuthi iyiphi inguqulo oyitholayo, umuthi usebenza ngendlela efanayo futhi unempumelelo efanayo. Ithimba lakho lokunakekelwa kwezempilo lizosebenzisa noma iyiphi inguqulo etholakalayo esikhungweni sabo, futhi ungethemba ukuthi zonke izinguqulo zihlangabezana nezindinganiso ezifanayo zokuphepha nekhwalithi.

Ezinye izindlela ze-Labetalol IV

Eminye imithi eminingi ingasetshenziswa esikhundleni se-labetalol IV ekwelapheni umfutho wegazi ophezulu onzima, futhi udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe esimweni sakho esithile kanye nomlando wezokwelapha.

Ezinye izindlela ezivamile zifaka i-nicardipine IV, esebenza ngokukhulula imithambo yegazi kodwa ayithinti izinga lokushaya kwenhliziyo yakho ngendlela efanayo ne-labetalol. I-Esmolol enye inketho esebenza ngendlela efana ne-labetalol kodwa inesikhathi esifushane sokusebenza, okwenza kube lula ukuyihlehlisa uma kudingeka.

Ezimweni ezithile, odokotela bangase bakhethe i-hydralazine IV, esebenza ikakhulukazi ngokukhulula imithambo yegazi, noma i-clevidipine, umuthi omusha ohlinzeka ngokulawulwa okunembile kakhulu komfutho wegazi. Ukukhetha kuncike ezintweni ezinjengesimo senhliziyo yakho, ukusebenza kwezinso, nokuthi umfutho wegazi lakho udinga ukwehliswa ngokushesha kangakanani.

Ithimba lakho lokunakekelwa kwezempilo lizokhetha umuthi ophephe kakhulu futhi osebenza kahle kakhulu esimweni sakho esithile, licabangela zonke izici zempilo yakho kanye nomlando wezokwelapha.

Ingabe i-Labetalol IV ingcono kune-Nicardipine?

Kokubili i-labetalol IV kanye ne-nicardipine IV ziyimithi emihle kakhulu yokwelapha umfutho wegazi ophezulu kakhulu, kodwa zisebenza ngezindlela ezihlukene futhi zingase zifaneleke kangcono ezimweni ezihlukene.

I-Labetalol ithinta kokubili inhliziyo yakho nemithambo yegazi, okuyenza ilungele ikakhulukazi abantu abanomfutho wegazi ophezulu ohlobene kokubili nesilinganiso senhliziyo esisheshayo kanye nemithambo yegazi eqinile. Ivame ukukhethwa kwabesifazane abakhulelwe ngoba inerekhodi elide lokuphepha ngesikhathi sokukhulelwa.

I-Nicardipine ikakhulukazi iphumuza imithambo yegazi ngaphandle kokuthinta kakhulu izinga lenhliziyo yakho, okuyenza ibe yindlela enhle yokukhetha kubantu abanezinkinga ezithile zesigqi senhliziyo noma labo abadinga ukulawulwa komfutho wegazi okunembile kakhulu. Kungase kusebenze ngendlela engcono kubantu abathile, ikakhulukazi labo abanezinkinga zezinso.

Ithimba lakho lezempilo lizokhetha umuthi ongcono kakhulu esimweni sakho esithile ngokusekelwe ezintweni ezinjengempilo yakho yonke, eminye imithi oyithathayo, nokuthi umzimba wakho uvame ukusabela kanjani ekwelashweni komfutho wegazi.

Imibuzo Evame Ukubuzwa Mayelana ne-Labetalol IV

Ingabe i-Labetalol IV iphephile kubantu abanesifo sikashukela?

I-Labetalol IV ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa ithimba lakho lezempilo lizokuqapha eduze. Umuthi ungase ufihle ezinye izimpawu zokuxwayisa zikashukela ophansi, njengokushaya kwenhliziyo okusheshayo, ngakho amazinga kashukela egazini lakho azohlolwa njalo ngenkathi uthola umuthi.

Uma unesifo sikashukela, qiniseka ukuthi utshela ithimba lakho lezempilo ngayo yonke imithi yakho yesifo sikashukela, okuhlanganisa i-insulin nemithi yomlomo. Kungase kudingeke ukuthi balungise ukwelashwa kwakho isifo sikashukela okwesikhashana ngenkathi uthola i-labetalol IV ukuze kuvinjelwe izinkinga zikashukela egazini.

Ngingenzani uma ngizwa imiphumela emibi evela ku-Labetalol IV?

Njengoba i-labetalol IV inikezwa endaweni yasesibhedlela, akudingeki ukhathazeke ngokulawula imiphumela emibi uwedwa. Ithimba lakho lezempilo likuqapha ngokuqhubekayo futhi lizoxazulula ngokushesha noma yimiphi imiphumela emibi oyitholayo.

Uma uzizwa unesiyezi, unesiyezi, noma uqaphela noma yiziphi izimpawu ezingavamile, vele wazise umhlengikazi wakho noma udokotela ngokushesha. Bangashintsha umthamo wakho wemithi, bashintshe isikhundla sakho, noma banikeze ezinye izindlela zokwelapha ukukusiza ukuthi uzizwe ukhululekile ngenkathi usaqhubeka nokwelapha umfutho wegazi lakho.

Kwenziwani Uma Ngingaphuthelwa Umthamo We-Labetalol IV?

Akudingeki ukhathazeke ngokulahlekelwa imithamo ye-labetalol IV ngoba inikezwa ithimba lakho lezempilo endaweni yezokwelapha elawulwayo. Abahlengikazi nodokotela bakho banomthwalo wokuqinisekisa ukuthi uthola imithi ngendlela enembile njengoba kunqunyiwe.

Umuthi unikezwa njengemijovo ehleliwe noma njengokuthontsiza okuqhubekayo, futhi ithimba lakho lezempilo liqapha umfutho wakho wegazi njalo ukuze liqinisekise ukuthi uthola inani elilungile ngesikhathi esifanele.

Ngingayeka nini Ukuthatha I-Labetalol IV?

Ithimba lakho lezempilo lizinqumela ukuthi lingayeka nini i-labetalol IV ngokusekelwe ekufundweni komfutho wegazi lakho kanye nesimo sakho esiphelele. Ngokuvamile, umuthi uncishiswa kancane kancane kunokuthi uyekwe kungazelelwe ukuvimbela umfutho wegazi lakho ukuthi ungabuyi.

Abantu abaningi bashintsha besuka ku-IV labetalol baya emithini yomfutho wegazi ngomlomo ngaphambi kokushiya isibhedlela. Udokotela wakho uzoqinisekisa ukuthi umfutho wegazi lakho uhlala uzinzile ngemithi yomlomo ngaphambi kokuthi ukhishwe, futhi uzothola imiyalelo ecacile mayelana nokuqhubeka nokwelashwa komfutho wegazi ekhaya.

Ingabe I-Labetalol IV Ingabangela Imiphumela Yesikhathi Eside?

I-Labetalol IV ngokwayo ngokuvamile ayibangeli imiphumela yesikhathi eside uma isetshenziswa ngendlela efanele endaweni yezokwelapha. Umuthi uphuma ngokushesha ohlelweni lwakho uma uyekwa, futhi imiphumela eminingi emibi iyanyamalala ngokushesha ngemva kokuphela kokwelashwa.

Noma kunjalo, isimo esiyisisekelo esidinga ukwelashwa okuphuthumayo komfutho wegazi singase sibe nemiphumela yesikhathi eside empilweni yakho. Ithimba lakho labezempilo lizosebenza nawe ukuthuthukisa uhlelo lwesikhathi eside lokuphatha umfutho wakho wegazi nokuvimbela izimo eziphuthumayo zesikhathi esizayo ngokushintsha indlela yokuphila nokunakekelwa kwezempilo okuqhubekayo.