Yini i-Lacosamide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Lacosamide iyimithi kadokotela esetshenziselwa ikakhulukazi ukulawula ukuquleka kubantu abanesifo sokuwa. Ingaphansi kohlu lwemithi olubizwa ngokuthi ama-anticonvulsants noma imithi elwa nokuquleka, esebenza ngokuzinzisa umsebenzi kagesi ebuchosheni bakho ukuvimbela ukuquleka ukuthi kungenzeki.

Le mithi isibe yindlela ebalulekile yokwelapha abantu abaningi abaphila nesifo sokuwa selokhu yathola imvume ye-FDA. Ukuqonda ukuthi isebenza kanjani, uma inikezwa, nokuthi yini ongayilindela kungakusiza uzizwe uqiniseka kakhulu ngohambo lwakho lokwelashwa.

Yini i-Lacosamide?

I-Lacosamide iyimithi elwa nokuquleka esiza ukuvimbela ukuquleka kwe-epileptic ngokuthinta iziteshi ze-sodium ebuchosheni bakho. Cabanga ngalezi ziteshi njengamasango amancane alawula amasignali kagesi phakathi kwamaseli obuchopho.

Lapho lezi zimpawu zikagesi ziba nesiphithiphithi noma zidlula, ukuquleka kungenzeka. I-Lacosamide isebenza ngokunciphisa kancane lezi zimpawu zikagesi ezingaphezu kwamandla, okusiza ukubuyisela iphethini elilinganiselwe kakhulu yomsebenzi wobuchopho. Lokhu kwenza kungenzeki ukuthi ukuquleka kuqale noma kusabalale.

Le mithi ithathwa njengomuthi olwa nokuquleka wesizukulwane esisha, okusho ukuthi ingase ibe nokuxhumana okuncane neminye imithi uma iqhathaniswa nemithi endala yokuquleka. Udokotela wakho uzonquma ukuthi le mithi ilungele isimo sakho esithile.

Isetshenziselwa Ukuthini i-Lacosamide?

I-Lacosamide inikezwa ikakhulukazi ukwelapha ukuquleka okuthatha ingxenye kubantu abadala kanye nezingane ezineminyaka engu-4 nangaphezulu. Lokhu ukuquleka okuqala endaweni eyodwa yobuchopho futhi kungase kusabalale noma kungasabalali kwezinye izindawo.

Udokotela wakho angase anikeze i-lacosamide ngezindlela ezimbili eziyinhloko. Okokuqala, ingasetshenziswa kanye neminye imithi elwa nokuquleka lapho ukwelashwa kwakho kwamanje kungalawuli ngokugcwele ukuquleka kwakho. Okwesibili, kwezinye izimo, ingase inikezwe njengomuthi owodwa wokulawula ukuquleka.

Umuthi ulusizo ikakhulukazi kubantu abahlangabezana nokuthuthumela okugxilile, okubizwa nangokuthi ukuthuthumela okuyingxenye. Lokhu kuthuthumela kungase kubangele izimpawu ezinjengokunyakaza okungavamile, imizwa, noma izinguquko ekuqwashiseni, kuye ngokuthi iyiphi ingxenye yobuchopho bakho ethintekile.

Isebenza Kanjani I-Lacosamide?

I-Lacosamide isebenza ngokugxila kumashaneli athile e-sodium kumaseli akho obuchopho. Lawa mashaneli anjengeminyango elawula ukuthi amasignali kagesi angadlula nini phakathi kwamaseli obuchopho.

Lapho kwenzeka ukuthuthumela, amaseli obuchopho avame ukukhipha amasignali kagesi ngokushesha kakhulu noma ngamaphethini angavamile. I-Lacosamide isiza ukunciphisa lokhu kusebenza kagesi okweqile ngokuthinta indlela la mashaneli e-sodium asebenza ngayo. Lokhu kudala indawo kagesi ezinzile ebuchosheni bakho.

Lo muthi kucatshangwa ukuthi unamandla amaphakathi phakathi kwemithi elwa nokuthuthumela. Isebenza kahle ngokwanele ukulawula ukuthuthumela kubantu abaningi, kodwa ngokuvamile iyabekezeleleka kahle uma isetshenziswa njengoba kuqondiswe ngumhlinzeki wakho wezempilo.

Kufanele Ngiyithathe Kanjani I-Lacosamide?

Thatha i-lacosamide ngendlela eqondile udokotela wakho ayiyalayo, ngokuvamile kabili ngosuku ngaphandle noma ngaphandle kokudla. Ungayithatha ngamanzi, ubisi, noma ijusi ngokokukhetha kwakho, njengoba ukudla kungawuthinti ngendlela enkulu umzimba wakho oyamukela ngayo umuthi.

Uma unesizungu esizwelayo, ukuthatha i-lacosamide nokudla noma ubisi kungasiza ekunciphiseni noma yikuphi ukuphatheka kabi kokugaya ukudla. Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo omuthi ohlelweni lwakho.

Gwinya amaphilisi wonke kunokuthi uwachoboze, uwahlafune, noma uwaqhekeze. Uma uthatha uhlobo oluyincithiselo, sebenzisa idivayisi yokulinganisa enikezwe yikhemisi lakho ukuze uqinisekise ukuthi ukala ngendlela efanele. Ungalokothi usebenzise izipuni zasendlini, njengoba zingase zingakunikezi umthamo ofanele.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Lacosamide?

I-Lacosamide ngokuvamile iyindlela yokwelapha isikhathi eside se-epilepsy, futhi abantu abaningi kudingeka bayithathe iminyaka eminingi noma impilo yabo yonke. Ubude besikhathi sincike ekuphenduleni kwakho umuthi kanye nephathini yakho yokuhlaselwa.

Udokotela wakho uzohlala eqapha intuthuko yakho futhi angase alungise uhlelo lwakho lokwelapha ngokuhamba kwesikhathi. Abanye abantu bafinyelela ekulawuleni okuhle kakhulu kokuhlaselwa futhi baqhubeke nokuthatha umuthi unomphela, kanti abanye bangase bagcine bedlulela kwezinye izindlela zokwelapha.

Ungayeki ukuthatha i-lacosamide ngokuzumayo, ngisho noma uzizwa kahle noma ungabi nakho ukuhlaselwa isikhashana. Ukuyeka imithi yokulwa nokuhlaselwa ngokuzumayo kungabangela ukuhlaselwa okusha noma ngisho nesimo esiyingozi esibizwa ngokuthi i-status epilepticus. Udokotela wakho uzokuqondisa kunoma yiziphi izinguquko emthini wakho.

Yiziphi Imiphumela Eceleni Ye-Lacosamide?

Njengayo yonke imithi, i-lacosamide ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi imild kuya kwemaphakathi futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Imiphumela emibi evamile abantu abaningi abayitholayo ihlanganisa isiyezi, ikhanda, isicanucanu, nombono ophindwe kabili. Lezi zimpawu zivame ukubonakala kakhulu uma uqala ukuthatha umuthi noma lapho umthamo wakho ukhuphuka.

Nawa imiphumela emibi ebikwa kaningi ongase uyithole:

• Isiyezi noma ukuzizwa ungaqinile
• Ikhanda
• Isicanucanu noma isisu esibuhlungu
• Umbono ophindwe kabili noma umbono ongacacile
• Ukukhathala noma ukozela
• Izinkinga zokuxhumana
• Ukuthuthumela noma ukuzamazama

Le miphumela emibi evamile ivame ukuba ngaphansi kokuphazamisa njengoba umzimba wakho ujwayela umuthi, ngokuvamile kungakapheli amasonto ambalwa uqale ukwelashwa noma ukulungiswa komthamo.

Imiphumela emibi engathi sína ingenzeka, nakuba ingavamile. Lokhu kudinga ukunakekelwa kwezempilo ngokushesha futhi akufanele kungashaywa indiva.

Xhumana nodokotela wakho ngokushesha uma uthola noma yiziphi lezi zimpawu ezikhathazayo:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ushintsho olukhulu lwemizwa noma imicabango yokuzibulala
• Ukuphendula okukhulu kwesikhumba noma ukuqubuka
• Ukuphefumula noma ukugwinya kanzima
• Izinkinga ezinkulu zokuxhumana noma ukuwa

Imiphumela emibi engavamile kodwa engathi sína ihlanganisa izinkinga zesigqi senhliziyo nokuphendula okukhulu komzimba. Nakuba lokhu kungavamile, kubalulekile ukukwazi lokhu futhi ufune ukwelashwa ngokushesha uma kwenzeka.

Ubani Ongafanele Athathe I-Lacosamide?

I-Lacosamide ayifanele wonke umuntu, futhi izimo ezithile zezokwelapha noma izimo zingenza kungafaneleki kuwe. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyala lo muthi.

Abantu abanezimo ezithile zenhliziyo kufanele basebenzise i-lacosamide ngokucophelela okwengeziwe. Uma unezinkinga zesigqi senhliziyo, ukuvaleka kwenhliziyo, noma isifo senhliziyo esibi, udokotela wakho kungadingeka akuqaphele eduze noma acabangele ezinye izindlela zokwelapha.

Kufanele wazise udokotela wakho uma unezinye zalezi zimo ngaphambi kokuqala i-lacosamide:

• Ukuphazamiseka kwesigqi senhliziyo noma ukuvaleka kwenhliziyo
• Isifo senhliziyo esibi
• Isifo sezinso noma ukuncipha komsebenzi wezinso
• Isifo sesibindi
• Umlando wokucindezeleka noma imicabango yokuzibulala
• Ukungezwani komzimba ne-lacosamide noma imithi efanayo

Izinto ezikhethekile zisebenza kwabesifazane abakhulelwe nabancelisayo, njengoba ukuphepha kwe-lacosamide ngesikhathi sokukhulelwa kungaqinisekiswanga ngokugcwele. Udokotela wakho uzohlola izinzuzo nezingozi uma uhlela ukukhulelwa noma usuvele ukhulelwe.

Amagama Omkhiqizo we-Lacosamide

I-Lacosamide itholakala ngaphansi kwegama lomkhiqizo elithi Vimpat, elikhiqizwa yi-UCB Pharma. Lena inguqulo yomkhiqizo eyaneliswa kakhulu yomuthi.

Izinhlobo ezivamile ze-lacosamide nazo ziyatholakala futhi ziqukethe isithako esifanayo esisebenzayo njengohlobo lomkhiqizo. Imithi ejwayelekile ihlolwa ngokuqinile ukuqinisekisa ukuthi isebenza ngendlela efanayo nemithi yegama lomkhiqizo.

Ikhemisi lakho lingase lithathele indawo i-lacosamide ejwayelekile ngohlobo lomkhiqizo ngaphandle uma udokotela wakho efuna ngokuqondile igama lomkhiqizo. Zombili izinhlobo zisebenza ngendlela efanayo ekwelapheni ukuquleka uma zisetshenziswa njengoba zibhaliwe.

Ezinye Izindlela ze-Lacosamide

Eminye imithi eminingi yokulwa nokuquleka ingasetshenziswa njengezinye izindlela ze-lacosamide, kuye ngohlobo lwakho oluthile lokuquleka nesimo sakho sezokwelapha. Udokotela wakho uzosiza ekunqumeni inketho engcono kakhulu kuwe.

Ezinye izindlela ezivamile zihlanganisa i-levetiracetam, i-lamotrigine, ne-oxcarbazepine. Ngamunye wale mithi usebenza kancane ngendlela ehlukile futhi angase abe namaphrofayili ahlukene emiphumeleni engemihle, okuzocatshangelwa udokotela wakho lapho enza izinqumo zokwelapha.

Ukukhetha enye indlela kuncike ezintweni ezifana nohlobo lokuquleka kwakho, eminye imithi oyithathayo, imiphumela engemihle engaba khona, nokuphendula kwakho ngakunye ekwelashweni. Ngezinye izikhathi, inhlanganisela yemithi isebenza kangcono kunemithi eyodwa yokulawula ukuquleka.

Ingabe i-Lacosamide Ingcono Kune-Levetiracetam?

Kokubili i-lacosamide ne-levetiracetam ziyimithi ephumelelayo yokulwa nokuquleka, kodwa akukho noyedwa

Udkt wakho uzocabangela izinto ezifana nephathini yakho yokuhlaselwa, ezinye izimo zempilo, imithi yamanje, kanye nemiphumela engaba khona uma ekhetha phakathi kwalezi zinketho. Abanye abantu benza ngcono ngomuthi owodwa, kanti abanye bathola imiphumela engcono ngomunye.

Imibuzo Evame Ukubuzwa Mayelana ne-Lacosamide

Ingabe i-Lacosamide iphephile kubantu abanezifo zenhliziyo?

I-Lacosamide idinga ukuqapha ngokucophelela kubantu abanezifo zenhliziyo, ikakhulukazi labo abanezinkinga zesigqi senhliziyo noma ukuvinjelwa kwenhliziyo. Umuthi ungase ukwazi ukuthinta isigqi senhliziyo, ngakho udokotela wakho angase ayale ukuhlolwa kwenhliziyo ngaphambi nangemva kokwelashwa.

Uma unesifo senhliziyo, udokotela wakho uzokala izinzuzo zokulawula ukuhlaselwa ngokumelene nezingozi ezingaba khona ezihlobene nenhliziyo. Bangase bakuqale ngomthamo ophansi futhi baqaphe ukusebenza kwenhliziyo yakho eduze ngesikhathi sokwelashwa.

Ngingenzani uma ngiphuzile i-Lacosamide eningi ngengozi?

Uma ngengozi uphuza i-lacosamide eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ungalindi ukuthi izimpawu zivele, ngoba isenzo esisheshayo sibalulekile ekuphepheni kwakho.

Izimpawu zokweqisa zingabandakanya isiyezi esibi, izinkinga zokuxhumana, noma izinguquko esigqini senhliziyo. Uma uhlangabezana nezimpawu ezinzima, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha kunokulinda ukukhuluma nodokotela wakho ovamile.

Ngingenzani uma ngiphuthelwa umthamo we-Lacosamide?

Uma uphuthelwa umthamo we-lacosamide, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho yokulinganisa ejwayelekile.

Ungalokothi uphindaphinde imithamo ukuze ulungise eyodwa ephuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusebenzisa umhleli wamaphilisi noma ukusetha izikhumbuzi zocingo ukukusiza ukuthi uhlale emgqeni.

Ngingayeka nini ukuthatha i-Lacosamide?

Kufanele uyeke ukuthatha i-lacosamide ngaphansi kokuqondisa kukadokotela wakho kuphela, ngisho noma ungabi nokuquleka isikhathi eside. Udokotela wakho uzohlola ukulawulwa kwakho kokuquleka, impilo yakho yonke, nezinye izinto ngaphambi kokwenza noma yiziphi izinguquko ekwelashweni kwakho.

Uma udokotela wakho enquma ukuthi kufanelekile ukuyeka i-lacosamide, bazokwenza isimiso sokunciphisa kancane kancane ukuze banciphise kancane umthamo wakho emasontweni amaningana noma izinyanga. Lokhu kusiza ekuvimbeleni ukuquleka okungase kwenzeke lapho imithi yokulwa nokuquleka iyekwa ngokushesha kakhulu.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Lacosamide?

Utshwala bungandisa imiphumela yokuthulisa ye-lacosamide futhi kungenzeka yenze imiphumela emibi efana nesiyezi nezinkinga zokuxhumana zibe zimbi. Ngokuvamile kungcono ukukhawulela noma ukugwema utshwala ngenkathi uthatha lo muthi.

Uma ukhetha ukuphuza utshwala, kwenze ngokulinganisela futhi uqaphele kakhulu ngemisebenzi edinga ukuxhumana noma ukuqapha. Njalo xoxa ngokusebenzisa utshwala nodokotela wakho, njengoba bengakunikeza isiqondiso esiqondene nawe esisekelwe esimweni sakho esithile neminye imithi ongase uyithathe.