Yini i-Lamotrigine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Lamotrigine iyimithi kadokotela esiza ukuzinzisa umsebenzi kagesi ebuchosheni bakho. Ivame ukusetshenziselwa ukwelapha isithuthwane kanye nesifo se-bipolar ngokuvimbela ukuquleka kanye nezigameko zemizwa. Le mithi isebenza njengesistimu yamabhuleki emnene yamaseli obuchopho asebenza ngokweqile, iwawasize ukuthi axhumane ngokushelela futhi inciphise ukuqhuma okungazelelwe komsebenzi kagesi okungadala izinkinga.

Yini i-Lamotrigine?

I-Lamotrigine ingeyeqembu lemithi ebizwa ngokuthi ama-anticonvulsants noma ama-mood stabilizers. Ekuqaleni yathuthukiswa ukwelapha isithuthwane kodwa odokotela bathola ukuthi futhi isiza ukuphatha isifo se-bipolar ngempumelelo. Umuthi uza ngamaphilisi, amaphilisi okuhlafunwa, namaphilisi aqeda ngomlomo ancibilika olimini lwakho.

Le mithi ithathwa njengenketho ethembekile, efundwe kahle esize izigidi zabantu ukuphatha izimo zabo ngokuphepha. Sekutholakala iminyaka engaphezu kwengamashumi amabili, inikeza odokotela ulwazi oluningi ngokuthi isebenza kanjani nokuthi yini okufanele bayilindele.

Isetshenziselwani i-Lamotrigine?

I-Lamotrigine iphatha izimo ezimbili eziyinhloko: isithuthwane kanye nesifo se-bipolar. Ngesithuthwane, ivimbela izinhlobo ezahlukene zokuquleka ukuthi zenzeke. Ngesifo se-bipolar, sisiza ukuvimbela izigameko zokucindezeleka futhi singanciphisa imvamisa yokushintsha kwemizwa.

Udokotela wakho angase akubhalele i-lamotrigine uma uneziqephu ze-focal, iziqephu ezijwayelekile, noma i-Lennox-Gastaut syndrome (uhlobo oluqinile lwesithuthwane sobuntwana). Esifweni se-bipolar, isebenza ikakhulukazi ekuvikeleni uhlangothi lokucindezeleka lwezigameko zemizwa, nakuba ingasizi kangako ezigamekweni ze-manic.

Ngezinye izikhathi odokotela babhala i-lamotrigine ezinye izimo ezinjengohlobo oluthile lobuhlungu bemizwa noma njengokwelashwa okwengeziwe lapho eminye imithi ingasebenzi kahle ngokwanele. Lokhu kubizwa ngokuthi ukusetshenziswa “ngaphandle kwelebula”, okusho ukuthi umuthi ungasiza ngisho noma ekuqaleni ungazange wenzelwe lezi zinkinga ezithile.

Isebenza Kanjani I-Lamotrigine?

I-Lamotrigine isebenza ngokuvimba iziteshi ze-sodium emangqamuzaneni akho obuchopho, okusiza ukulawula amasignali kagesi. Cabanga ngayo njengokulungisa ivolumu kumasekhethi obuchopho asebenzayo ngokweqile angase ashaye ngokushesha kakhulu noma ngendlela engalindelekile.

Lo muthi uthathwa njengenketho yokwelapha enamandla aphakathi nendawo. Awunamandla njengeminye imithi yokulwa nokuthuthumela, kodwa ngokuvamile inobungane emzimbeni wakho ngemiphumela emincane. Lokhu kuyenza ibe yindlela enhle kubantu abadinga ukwelashwa kwesikhathi eside noma abake baba nezinkinga ngeminye imithi.

Umuthi wakha kancane kancane ohlelweni lwakho emavikini amaningana. Lokhu kwakheka kancane empeleni kuyasiza ngoba kunciphisa ingozi yemiphumela emibi engathi sína futhi kusiza umzimba wakho ukuthi ujwayele ukwelashwa.

Kufanele Ngiyithathe Kanjani I-Lamotrigine?

Thatha i-lamotrigine ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye noma kabili ngosuku. Ungayithatha ngaphandle kokudla noma ngaphandle kokudla, kodwa ukuyithatha nokudla kungasiza ukunciphisa ukuphazamiseka kwesisu uma uzwela.

Gwinya amaphilisi avamile wonke ngamanzi. Uma unamaphilisi okuhlafunwa, ungaqeda ukuwahlafuna noma uwaqede wonke. Ngamaphilisi anyibilika ngomlomo, uwabeke olimini lwakho bese uwavumela ukuthi ancibilike - akudingeki amanzi.

Zama ukuthatha umuthi wakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Lokhu kuvumelana kusiza umuthi ukuthi usebenze ngempumelelo futhi kunciphisa ithuba lokuthuthumela noma iziqephu zemizwa.

Udokotela wakho cishe uzoqala ngomthamo ophansi bese ewunyusa kancane kancane emavikini amaningana. Lokhu kwanda kancane kubalulekile ekuphepheni kwakho, ngakho-ke ungageqi imithamo noma uzame ukusheshisa inqubo ngokwakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Lamotrigine?

Abantu abaningi bathatha i-lamotrigine izinyanga eziya eminyakeni, kuye ngesimo sabo. Ngokuqondene nesithuthwane, ungase uyidinge isikhathi eside ukuvimbela ukuvela kabusha kwezithuthwane. Ngokuqondene nokuphazamiseka kwengqondo, ivame ukusetshenziswa njengokwelashwa kokugcina ukuvimbela izigameko zemizwa zesikhathi esizayo.

Udokotela wakho uzobuyekeza njalo ukuthi umuthi usebenza kahle kangakanani nokuthi usawudinga yini. Abanye abantu abanesithuthwane bangase bakwazi ukuyeka ukuyithatha ngemva kokungabi nazithuthwane iminyaka eminingi, kodwa lesi sinqumo sidinga ukugadwa ngokucophelela kwezokwelapha.

Ungayeki ukuthatha i-lamotrigine ngokuzumayo, ngoba lokhu kungabangela izithuthwane noma izigameko zemizwa. Uma udinga ukuyeka, udokotela wakho uzokwenza uhlelo lokunciphisa kancane kancane umthamo wakho emasontweni amaningana noma izinyanga.

Yiziphi Imiphumela Eceleni ye-Lamotrigine?

Abantu abaningi bayamukela kahle i-lamotrigine, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi evame kakhulu ongase uyithole, cishe ngokulandelana kusuka kokuvame kakhulu kuya kokungavamile:

• Isiyezi noma ukuzwa ungazinzile
• Ikhanda
• Isicanucanu noma isisu esibuhlungu
• Ukozela noma ukukhathala
• Ukubona kabili noma ukubona okungacacile
• Ukuqubuka kwesikhumba (ngokuvamile okulula)
• Ubunzima bokulala
• Ukuthuthumela noma ukuzamazama

Le miphumela emibi ejwayelekile ivame ukwehla njengoba umzimba wakho ujwayela umuthi. Uma ziqhubeka noma zikuphazamisa kakhulu, khuluma nodokotela wakho mayelana nokulungisa umthamo wakho noma isikhathi.

Kukhona nemiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezokwelapha ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukwazi ukuthi yini okufanele uyibheke:

• Ukuqubuka kwesikhumba okukhulu okuhambisana nomkhuhlane, ama-lymph nodes avuvukile, noma izilonda zomlomo
• Ukuphuma kwegazi okungavamile noma ukulimala
• Ushintsho olukhulu lwemizwa noma imicabango yokuzilimaza
• Izimpawu zezinkinga zesibindi (ukuphuzi kwesikhumba noma amehlo, umchamo omnyama, ubuhlungu obukhulu besisu)
• Isiyezi esikhulu noma ukuquleka
• Ukuqina kwentamo okuhambisana nomkhuhlane

Into ekhathaza kakhulu nge-lamotrigine ukusabela okukhulu kwesikhumba okubizwa nge-Stevens-Johnson syndrome, okwenzeka cishe kumuntu oyedwa kwabayi-1,000. Lokhu kuvamile ukwenzeka emasontweni angu-8 okuqala okwelashwa futhi kungenzeka uma uqala ngomthamo ophezulu kakhulu noma usebenzisa eminye imithi ethile.

Ubani Ongafanele Athathe I-Lamotrigine?

I-Lamotrigine ayilungile kuwo wonke umuntu. Udokotela wakho uzocabangela ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Akufanele uthathe lo muthi uma uke waba nokusabela okukhulu kuwo ngaphambili.

Abantu abanezimo ezithile badinga ukuqapha okwengeziwe noma bangase badinge ukugwema i-lamotrigine ngokuphelele. Lokhu kuhlanganisa abantu abanezifo zesibindi ezinzima, izinhlobo ezithile zezinkinga zokushaya kwenhliziyo, noma umlando wokuphendula okukhulu kwesikhumba kweminye imithi.

Uma ukhulelwe noma uhlela ukukhulelwa, xoxa ngalokhu ngokucophelela nodokotela wakho. I-Lamotrigine ingasetshenziswa ngesikhathi sokukhulelwa lapho izinzuzo zidlula izingozi, kodwa idinga ukuqapha ngokucophelela nokulungiswa komthamo.

Izingane ezingaphansi kweminyaka emi-2 ngokuvamile azitholi i-lamotrigine ngaphandle kwezimo ezithile kakhulu, njengoba ziba nengozi enkulu yokusabela okukhulu kwesikhumba. Abantu abadala bangase badinge imithamo ephansi ngoba imizimba yabo icubungula umuthi kancane.

Amagama Omkhiqizo we-Lamotrigine

I-Lamotrigine itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Lamictal iyona eyaziwa kakhulu. Amanye amagama omkhiqizo afaka i-Lamictal XR (inguqulo yokukhishwa okweluliwe), i-Lamictal ODT (amaphilisi aqeda ngomlomo), kanye ne-Lamictal CD (amaphilisi athambile aqhekekayo).

Izinhlobo ezivamile ze-lamotrigine zitholakala kabanzi futhi zisebenza ngempumelelo njengezinhlobo ezinamagama. Ikhemisi lakho lingase lithathe indawo ngohlobo olujwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo.

Uma ushintsha phakathi kwabakhiqizi abahlukene be-lamotrigine, yazisa udokotela wakho. Ngenkathi kufanele basebenze ngendlela efanayo, abanye abantu baqaphela umehluko omncane endleleni abazizwa ngayo, futhi udokotela wakho angase afune ukukuqapha eduze ngesikhathi sokushintsha.

Ezinye Izindlela Zokwelapha ze-Lamotrigine

Eminye imithi eminingana ingelapha isithuthwane kanye nokuphazamiseka kwe-bipolar uma i-lamotrigine ingakulungele. Ngesithuthwane, ezinye izindlela zokwelapha zihlanganisa i-levetiracetam (Keppra), i-carbamazepine (Tegretol), kanye ne-valproic acid (Depakote).

Nokuphazamiseka kwe-bipolar, ezinye izidakamizwa zokuzinza kwemizwa zihlanganisa i-lithium, i-valproic acid, kanye nemithi ethile ye-antipsychotic efana ne-quetiapine (Seroquel) noma i-aripiprazole (Abilify). Ngayinye inezinzuzo zayo kanye nohlu lwemiphumela.

Udokotela wakho uzocabangela izinto ezinjengohlobo lwakho oluthile lokuquleka noma izimpawu ze-bipolar, eminye imithi oyithathayo, iminyaka yakho, kanye nendlela yakho yokuphila lapho ekhetha enye indlela engcono kakhulu. Ngezinye izikhathi inhlanganisela yemithi isebenza kangcono kunanoma iyiphi imithi eyodwa yodwa.

Ingabe i-Lamotrigine Ingcono Kune-Carbamazepine?

I-Lamotrigine ne-carbamazepine yomibili iyimithi ephumelelayo yokuquleka, kodwa isebenza ngendlela ehlukile futhi inezinzuzo ezihlukene. I-Lamotrigine ivame ukubangela imiphumela emincane futhi ivame ukubekezelelwa kangcono, ikakhulukazi ekusetshenzisweni kwesikhathi eside.

I-Carbamazepine ingasebenza kahle ezinhlotsheni ezithile zokuquleka, ikakhulukazi ukuquleka okugxilwe kukho, kodwa ihlangana neminye imithi eminingi futhi idinga ukuhlolwa kwegazi njalo ukuqapha ukusebenza kwesibindi kanye nokubala kwegazi. I-Lamotrigine ngokuvamile ayidingi ukuqapha igazi okujwayelekile.

Ngesifo se-bipolar, i-lamotrigine ivame ukukhethwa ngoba ilungele kakhulu ukuvimbela izigaba zokucindezeleka ezinemiphumela emincane. I-Carbamazepine ingasiza ngokuzinza kwemizwa kodwa ngokuvamile ithathwa njengenketho yesibili.

Ukukhetha okuthi "kungcono" kuncike ngokuphelele esimweni sakho, okuhlanganisa uhlobo lwakho lokuquleka, ezinye izimo zezokwelapha, imithi oyithathayo, nokuthi usabela kanjani ekwelashweni. Udokotela wakho uzokusiza ukuthi uhlole lezi zinto.

Imibuzo Evame Ukubuzwa Mayelana ne-Lamotrigine

Ingabe i-Lamotrigine iphephile ezigulini ezinokugula kwezinso?

I-Lamotrigine ngokuvamile iphephile kubantu abanezifo zezinso ngoba izinso zakho azicubungi iningi lalesi sithako. Isibindi sakho senza umsebenzi omkhulu wokuhlukanisa i-lamotrigine, ngakho izinkinga zezinso ngokuvamile azidingi ukulungiswa komthamo.

Nokho, uma unesifo esibi sezinso, udokotela wakho angase afune ukukuqapha eduze. Abanye abantu abanezinkinga zezinso nabo banezinye izimo zezempilo ezingase zithinte indlela i-lamotrigine esebenza ngayo emzimbeni wakho.

Ngingenzani uma ngiphuzile i-Lamotrigine eningi ngengozi?

Uma ucabanga ukuthi uphuze i-lamotrigine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa kahle. Ukuphuza okuningi kungabangela izimpawu ezinzima njengokugajwa okukhulu, izinkinga zokuxhumana, noma ngisho nokuquleka.

Ungazami ukuzenza uhlanze ngaphandle uma utshelwe ngokuqondile ukuthi wenze kanjalo ngumhlinzeki wezempilo. Uma othile engazi lutho noma enenkinga yokuphefumula, shayela izinsiza eziphuthumayo ngokushesha.

Ngingenzani uma ngiphuthelwa umthamo we-Lamotrigine?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho evamile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungandisa ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma ukusebenzisa umhleli wamaphilisi.

Ngingayeka nini ukuthatha i-Lamotrigine?

Yeka ukuthatha i-lamotrigine ngaphansi kokugadwa udokotela wakho kuphela. Nge-epilepsy, ungase ukwazi ukuyeka ngemva kokungabi nazimpawu iminyaka eminingana, kodwa lesi sinqumo sidinga ukuhlolwa ngokucophelela kwezici zakho zobungozi.

Nge-bipolar disorder, i-lamotrigine ivame ukusetshenziswa njengokwelashwa kwesikhathi eside. Ukuyeka kungazelelwe kungabangela izigaba zemizwa, ngakho noma yiziphi izinguquko ohlelweni lwakho lokwelashwa kufanele zixoxwe ngokucophelela nodokotela wakho kuqala.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Lamotrigine?

Inani elincane lotshwala ngokuvamile lilungile kubantu abaningi abathatha i-lamotrigine, kodwa utshwala bungakhuphula ukozela nesiyezi. Kungase futhi kubangele ukuquleka kubantu abane-epilepsy futhi kwenze izimpawu zemizwa zibe zimbi kwi-bipolar disorder.

Xoxa nodokotela wakho ngalokho okuphephile esimweni sakho esithile. Bangase batusa ukugwema utshwala ngokuphelele noma ukululinganisa ngamanani amancane kakhulu, kuye ngesimo sakho nokuthi izimpawu zakho zilawulwa kahle kangakanani.