Yini i-Lanreotide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Lanreotide iyikhambi elenziwe ngamachiza elilingisa i-somatostatin, i-hormone yemvelo umzimba wakho oyikhiqizayo ukuze ulawule imisebenzi ehlukahlukene. Le mithi ejovwayo isiza ukulawula ukukhiqizwa kwe-hormone okweqile ezimweni ezithile zezokwelapha, ikakhulukazi lezo ezithinta uhlelo lokugaya ukudla namathumba akhiqiza ama-hormone.

Uthola i-lanreotide njengomjovo ojulile ngaphansi kwesikhumba sakho, ngokuvamile kanye njalo emavikini amane. Cabanga ngayo njengomuthi osebenza isikhathi eside osebenza ngokuqhubekayo emzimbeni wakho ukuze ugcine amazinga e-hormone elinganiselwe lapho amasistimu akho emvelo engasebenzi kahle.

Yini i-Lanreotide Esetshenziselwa Yona?

I-Lanreotide iphatha izimo eziningana ezithile lapho umzimba wakho ukhiqiza khona ama-hormone amaningi. Ukusetshenziswa okuvame kakhulu yi-acromegaly, isimo lapho i-pituitary gland yakho yenza khona i-growth hormone eyeqile, okubangela izandla ezikhulisiwe, izinyawo, nezici zobuso.

Lo muthi futhi usiza ukuphatha amathumba e-neuroendocrine, okuyizikhula ezingavamile ezingathuthuka ezingxenyeni ezihlukahlukene zomzimba futhi zidedele ama-hormone ngendlela engafanele. Ngaphezu kwalokho, odokotela bancoma i-lanreotide ye-carcinoid syndrome, lapho amathumba athile abangela izimpawu ezinjengokukhanya, isifo sohudo, nezinkinga zenhliziyo.

Udokotela wakho angase futhi ancome i-lanreotide kwezinye izimo ezihlobene nama-hormone ngokusekelwe esimweni sakho esithile sezokwelapha. Ukusetshenziswa ngakunye kuncike ekulawuleni ukukhiqizwa kwe-hormone okweqile okubangela izimpawu ezingakhululeki noma eziyingozi.

Isebenza Kanjani I-Lanreotide?

I-Lanreotide isebenza ngokuvimba ama-receptors athile emzimbeni wakho avamela ukusabela ku-growth hormone nakwamanye ama-hormone. Ithathwa njengomuthi onamandla ngokulinganiselwe okhawulela ngempumelelo ukukhiqizwa kwe-hormone uma isetshenziswa ngendlela efanele.

Umuthi ubopha ezindaweni zokwamukela i-somatostatin emzimbeni wakho wonke, ikakhulukazi endleni yegland yegland kanye nohlelo lokugaya ukudla. Lesi senzo sokubopha sitshela amaseli akho akhiqiza ama-hormone ukuthi anciphise umsebenzi wawo, okufana nendlela iswishi yokukhanyisa enciphisa ngayo ukukhanya.

Ngenxa yokuthi i-lanreotide isebenza isikhathi eside, inikeza ukulawulwa okuzinzile kwama-hormone cishe amasonto amane ngemuva komjovo ngamunye. Lesi senzo esiqhubekayo sisiza ekuvikeleni ukuqubuka kwama-hormone okubangela izimpawu zakho eziningi.

Kufanele Ngiyithathe Kanjani I-Lanreotide?

I-Lanreotide iza njengesirinji egcwaliswe ngaphambili okumele ifakwe ngaphansi kwesikhumba sakho, ngokuvamile ethangeni lakho eliphezulu elingaphandle noma izinqulu. Abantu abaningi bathola lo mjovo ehhovisi likadokotela wabo noma emtholampilo ovela kumhlinzeki wokunakekelwa kwezempilo oqeqeshiwe.

Akudingeki ukuthi ulandele noma yiziphi iziqondiso ezikhethekile zokudla ngaphambi noma ngemuva komjovo wakho we-lanreotide. Umuthi usebenza ngokuzimela kokudla, ngakho-ke ungadla ngokujwayelekile ezinsukwini zomjovo.

Indawo yokujova kufanele ijikeleziswe ngaso sonke isikhathi ukuvimbela ukucasuka kwesikhumba. Umhlinzeki wakho wokunakekelwa kwezempilo uzohlanza indawo kahle ngaphambi kokunikeza umjovo futhi angase afake ibhandishi elincane ngemuva.

Abanye abantu bazwa ukungakhululeki okuncane endaweni yokujova, okuvame ukuxazululwa ngosuku olulodwa noma ezimbili. Ukusebenzisa i-compress ebandayo imizuzu embalwa kungasiza ekunciphiseni noma yikuphi ukuqaqamba.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Lanreotide?

Abantu abaningi bathatha i-lanreotide izinyanga kuya eminyakeni, kuye ngesimo sabo esithile nokuthi basabela kahle kangakanani ekwelashweni. Udokotela wakho uzoqapha amazinga akho ama-hormone nezimpawu njalo ukuze anqume ubude obufanele.

Nge-acromegaly, ukwelashwa kuvame ukuqhubeka isikhathi eside ngoba inkinga ye-pituitary eyisisekelo ngokuvamile ayixazululeki yodwa. Udokotela wakho uzohlola amazinga akho e-hormone yokukhula njalo ezinyangeni ezimbalwa ukuze aqinisekise ukuthi umuthi usebenza ngempumelelo.

Uma unezicubu ze-neuroendocrine, ubude bokwelashwa buxhomeke ezintweni ezinjengosayizi wesimila, indawo, nokuthi ngabe ezinye izindlela zokwelapha ziyasetshenziswa kanye ne-lanreotide. Abanye abantu badinga ukwelashwa iminyaka, kanti abanye bangase bakusebenzise isikhathi esifushane.

Ungayeki i-lanreotide ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokuphazima kweso kungabangela amazinga akho e-hormone ukuthi aphinde anyuke, abuyise izimpawu ezingakhululeki.

Ziyini Imiphumela Eceleni ye-Lanreotide?

Imiphumela ejwayelekile ye-lanreotide ngokuvamile iyalawuleka futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Abantu abaningi bathola izinguquko ezithile zokugaya ukudla, ezenzeka ngoba umuthi uthinta indlela umzimba wakho wokugaya ukudla osebenza ngayo.

Nansi imiphumela engase yenzeke, iqala ngaleyo ejwayelekile:

• Ukuqunjelwa noma izitulo ezixekile, okuvame ukuthuthuka ngemva kwamasonto ambalwa
• Ubuhlungu besisu noma ukucindezela, ngokuvamile okulula futhi okwesikhashana
• Isicanucanu, ikakhulukazi ngesikhathi sokujova kokuqala
• Ukuphendula endaweni yokujova njengobubomvu, ukuvuvukala, noma ukuzwela
• Amathambo e-gall, angase athuthuke ngokusetshenziswa kwesikhathi eside
• Ushintsho emazingeni kashukela egazi, okudinga ukuqapha uma unesifo sikashukela
• Ikhanda noma isiyezi, ngokuvamile okulula
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile

Le miphumela yokugaya ukudla yenzeka ngoba i-lanreotide yehlisa izinqubo ezithile zokugaya ukudla. Abantu abaningi bathola ukuthi le miphumela iba ngaphansi kokukhathaza ngokuhamba kwesikhathi njengoba imizimba yabo izivumela.

Imiphumela engajwayelekile kodwa ebucayi kakhulu ihlanganisa izinguquko ezinkulu ekushayeni kwenhliziyo, ubuhlungu obukhulu besisu obuvela emathanjeni e-gall, noma izimpawu zikashukela ophansi njengokuthuthumela nokudideka. Xhumana nodokotela wakho ngokushesha uma uthola noma yiziphi zalezi zimpawu ezibucayi.

Ubani Ongafanele Athathwe I-Lanreotide?

I-Lanreotide ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abanezimo ezithile zenhliziyo badinga ukuqashwa okwengeziwe ngoba umuthi ungathinta ukushaya kwenhliziyo.

Kufanele uxoxe nge-lanreotide ngokucophelela nodokotela wakho uma unesifo sikashukela, njengoba umuthi ungathinta ukulawulwa kukashukela egazini. Udokotela wakho kungadingeka alungise imithi yakho yesifo sikashukela noma isimiso sokuqapha.

Abantu abanezinkinga ze-gallbladder kufanele basebenzise i-lanreotide ngokucophelela ngoba ingakhuphula ingozi yamatshe e-gallstones. Udokotela wakho cishe uzoqapha ukusebenza kwe-gallbladder yakho ngezivivinyo zokuthwebula ezivamile.

Uma ukhulelwe noma uncelisa, khuluma nodokotela wakho ukuthi ngabe i-lanreotide iphephile yini kuwe. Imiphumela yomuthi ezinganeni ezisakhulayo ayiqondakali ngokugcwele, ngakho-ke udokotela wakho uzokala izinzuzo ngokumelene nezingozi ezingaba khona.

Amagama Omkhiqizo we-Lanreotide

I-Lanreotide itholakala ngaphansi kwegama lomkhiqizo elithi Somatuline Depot e-United States. Lolu uhlobo oluvame kakhulu ukunqunywa futhi luza njengesirinji egcwaliswe ngaphambili yokujova.

Kwamanye amazwe, i-lanreotide ingase itholakale ngaphansi kwamagama omkhiqizo ahlukene, kodwa isithako esisebenzayo nendlela esisebenza ngayo ihlala injalo. Umkhemisi wakho angakusiza ukuthi uqonde ukuthi yiluphi uhlobo olutholayo.

Zonke izinhlobo ze-lanreotide zisebenza ngendlela efanayo, kungakhathaliseki igama lomkhiqizo. Okubalulekile ukuthola umthamo ofanele ngezikhathi ezifanele njengoba kunqunywe udokotela wakho.

Ezinye izindlela ze-Lanreotide

Eminye imithi eminingi ingelapha izimo ezifanayo uma i-lanreotide ingasebenzi kahle kuwe noma ibangela imiphumela emibi. I-Octreotide ingenye i-somatostatin analog esebenza ngendlela efanayo kodwa idinga ukujova kaningi.

I-Pasireotide iyindlela entsha engasebenza kangcono kwabanye abantu abane-acromegaly abangaphenduli kahle ku-lanreotide. Kodwa-ke, ingaba nemiphumela emibi ehlukene, okuhlanganisa nemiphumela ebaluleke kakhulu kushukela wegazi.

Ezimweni ezithile, imithi yomlomo efana ne-cabergoline noma i-pegvisomant ingase ibe ezinye izindlela, kuye ngokuthi ukuxilongwa kwakho kanye namahomoni akho. Udokotela wakho uzocabangela isimo sakho ngasinye lapho exoxa ngezindlela ezingenye.

Ukuhlinzwa kungase futhi kube enye indlela yezinye izimo, ikakhulukazi uma unethumba le-pituitary elibangela i-acromegaly. Udokotela wakho uzoxoxa ngazo zonke izindlela zokwelapha ezitholakalayo ukuze athole indlela engcono kakhulu kuwe.

Ingabe i-Lanreotide ingcono kune-Octreotide?

Kokubili i-lanreotide ne-octreotide ziyizinto ezisebenzayo ze-somatostatin, kodwa zinezinye izinto ezingokoqobo ezingenza enye ifaneleke kakhulu kuwe. Inzuzo enkulu ye-Lanreotide ukulula, njengoba udinga kuphela imijovo kanye ngenyanga uma uqhathanisa ne-octreotide's dosing evame kakhulu.

Abantu abaningi bakhetha i-lanreotide ngoba isimiso somjovo wanyanga zonke kulula ukusiphatha nokusikhumbula. Lokhu kungaholela ekuthobeleni kangcono ukwelashwa, okubalulekile ekulawuleni izimo ezihlobene namahomoni ngempumelelo.

Ngokuqondene nokusebenza kahle, yomibili imithi isebenza kahle ngendlela efanayo kubantu abaningi. Abanye abantu bangase basabele kangcono komunye kunomunye, kodwa lokhu kuyahlukahluka kumuntu nomuntu futhi akunakwazi ukubikezelwa kusengaphambili.

Amaphrofayili emiphumela emibi afana kakhulu phakathi kwemithi emibili, nakuba abanye abantu bengase bakwazi ukubekezelela enye kangcono kunomunye. Udokotela wakho uzocabangela indlela yakho yokuphila, umlando wezokwelapha, nezintandokazi zokwelapha lapho ekhetha phakathi kwazo.

Imibuzo Evame Ukubuzwa Mayelana ne-Lanreotide

Ingabe i-Lanreotide iphephile kubantu abanesifo sikashukela?

I-Lanreotide ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela futhi mhlawumbe ukulungisa imithi yakho yesifo sikashukela. Umuthi ungathinta amazinga kashukela egazini, ngezinye izikhathi ubangele ukuthi ehlise kakhulu noma enyuke ngokungalindelekile.

Udktela wakho cishe uzofuna ukuhlola ushukela wakho wegazi kaningi uma uqala ukwelashwa nge-lanreotide. Bangase futhi balungise i-insulin yakho noma eminye imithi yesifo sikashukela ukuze babhekele indlela i-lanreotide ethinta ngayo ukulawulwa kukashukela wakho wegazi.

Kufanele ngenzeni uma ngisebenzisa i-Lanreotide eningi ngengozi?

Njengoba i-lanreotide inikezwa ochwepheshe bezempilo ezindaweni zomtholampilo, ukweqisa ngengozi akuvamile kakhulu. Uma ngandlela thize uthole i-lanreotide eningi, xhumana nodokotela wakho noma izinsiza eziphuthumayo ngokushesha.

Izimpawu ze-lanreotide eningi zingabandakanya isicanucanu esibi, ukuhlanza, isifo sohudo, noma ukwehla okukhulu kukashukela wegazi. Ungalindi ukubona ukuthi izimpawu ziyathuthuka yini – funa usizo lwezokwelapha ngokushesha uma usola ukweqisa.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Lanreotide?

Uma uphuthelwa umjovo wakho we-lanreotide ohleliwe, xhumana nehhovisi likadokotela wakho ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Ungalindi kuze kube yilapho uqokwe khona okulandelayo, njengoba lokhu kungavumela amazinga akho e-hormone ukuthi aphinde anyuke.

Udktela wakho angase ancome ukuthola umjovo ophuthelwe ezinsukwini ezimbalwa zosuku lwakho oluhleliwe, noma angase alungise uhlelo lwakho lokwelashwa kancane. Okubalulekile ukugcina ukulawulwa kwe-hormone okuqhubekayo ngaphandle kwegebe elikhulu ekwelashweni.

Ngingayeka nini ukuthatha i-Lanreotide?

Kufanele uyeke kuphela ukuthatha i-lanreotide ngaphansi kokuqondisa kukadokotela wakho, njengoba ukuyeka kungazelelwe kungabangela amazinga akho e-hormone ukuthi aphinde anyuke. Udokotela wakho uzocabangela izinto ezinjengamazinga akho e-hormone yamanje, ukulawulwa kwezimpawu, nempilo yonke lapho kuxoxwa ngokuyeka ukwelashwa.

Abanye abantu bangase bakwazi ukuyeka i-lanreotide uma isimo sabo esiyisisekelo sithuthuka noma uma benomsebenzi ohlinzayo ophumelelayo wokususa izimila ezikhiqiza ama-hormone. Kodwa-ke, abantu abaningi badinga ukwelashwa kwesikhathi eside ukuze bagcine ibhalansi efanele ye-hormone.

Ngingahamba yini ngenkathi ngithatha i-Lanreotide?

Yebo, ungahamba ngenkathi uthatha i-lanreotide, kodwa uzodinga ukuhlela imijovo yakho ngokuya ngohlelo lwakho lokuhamba. Xhumana nehhovisi likadokotela wakho kusenesikhathi ukuze nixoxe ngesikhathi sokujova kwakho ngaphambi noma ngemuva kohambo lwakho.

Uma uhamba phesheya isikhathi eside, udokotela wakho angase akwazi ukuhlela ukwelashwa esikhungweni sezokwelapha lapho uya khona, noma angase ashintshe uhlelo lwakho lokujova ukuze luhambisane nezinhlelo zakho zokuhamba.