Lapatinib (indindlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Tykerb
Mayelana naleli khambi
ILapatinib isetshenziswa ndawonye necapecitabine ukuze ikwelase i-breast cancer ephambilile noma e-metastatic (umdlavuza osevele usakazeke) ene-HER2-receptor positive kubantu abake bamukela ezinye izindlela zokwelapha umdlavuza (isib. anthracycline, taxane, trastuzumab) ezingazange zisebenze kahle. ILapatinib isetshenziswa futhi ndawonye neletrozole ukuze ikwelase abesifazane abangasekho esikhathini sokuya esikhathini abanemidlavuza ye-hormone-receptor positive ne-HER2-receptor positive e-metastatic. ILapatinib iyingxenye yeqembu lemithi ebizwa ngokuthi yi-antineoplastics (imithi yomdlavuza). Iphazamisa ukukhula kwamaselula omdlavuza, aqothulwa ekugcineni. Njengoba ukukhula kwamaselula avamile kungase kuthonyeke futhi yimithi, ezinye izingozi ezingafuneki nazo ziyoba khona. Ezinye zalezi zingaba nzima futhi kufanele zibikwe kudokotela wakho. Lolu hlobo lwemithi luyatholakala kuphela ngesikripthi sodokotela wakho. Lo mkhiqizo uyatholakala ngezindlela zokulinganisela ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucineni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqululo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engajwayelekile noma ebangelwa uketshezi kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezifo ezingalawuleki, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela yelapatinib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwelapatinib kubantu abadala. Noma kunjalo, abantu abadala banesizotha kakhulu kwimiphumela yale mithi kunabantu abadala abasebancane. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ukwanda kengozi yezinye iziphumo ezibuhlungu, kodwa ukusebenzisa kokubili izidakamizwa kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayikhuthazwa, kodwa kungaphepheki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi esetshenziswa ekwelapheni umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokuthola le mithi, qiniseka ukuthi uyayiqonda yonke imingcele nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho phakathi nokwelashwa kwakho. Thatha le mithi ngokuqondile njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Le mithi iza nephepha lokwazisa iziguli. Funda bese ulandela imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Thatha ithebulethi okungenani ihora elilodwa ngaphambi noma ihora elilodwa ngemuva kokudla. Zonke izithebulethi zithathwa ndawonye njengodose olulodwa. I-Lapatinib inikezwa ndawonye ne-capecitabine noma i-letrozole. Kubalulekile ukuthi uthathe umuthi ngamunye ngesikhathi esifanele. Landela imiyalo yodokotela wakho mayelana nokuthi nini kufanele uthathe le mithi. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mithi. Idosini yale mithi izohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela izilinganiso eziphakathi zale mithi. Uma idosi yakho ihlukile, ungayishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lomuthi othathayo lixhomeke emandleni omithi. Futhi, inani ledosini othathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezilinganiso, nobude besikhathi othatha umuthi kuya ngenkinga yezokwelapha oyisebenzisela umuthi. Uma uphuthelwa idosi yale mithi, yithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sedosi yakho elandelayo, skip idosi ephuthelwe bese ubuyela esikimini sakho sokuthola idosi. Ungawandisi amadosini. Gcina umuthi esitsheni esivaliwe emazingeni okushisa kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungawumisisi. Gcina ungafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uphule kanjani noma yimuphi umuthi ongase uwusebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.