Laronidase (indlela ye-intravenous)
Imikhiqizo etholakalayo
Aldurazyme
Mayelana naleli khambi
ILaronidase isetshenziswa ekwelapheni uhlobo lukaHurler noHurler-Scheie lwesifo se-mucopolysaccharidosis (MPS I) esibangelwa ukungabikho kwesenzimu ethile ebizwa ngokuthi yi-α-L-iduronidase emzimbeni. ILaronidase itholakala ngokwamanye kuphela ngokubhalwa kwesikhungo sezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma kunqunywe ukuthi kusetshenziswe iyeza, izingozi zokuthatha leliyeza kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Ngaleliyeza, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluhluke kakhulu noma oluhambisana nokwaleka kuleliyeza noma kwezinye izidakamizwa. Tshela odokotela wakho uma unanoma yiluphi olunye uhlobo lwezinto ozaleka kuzo, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngalezi zidakamizwa ezingabhalwanga, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenziwanga ngokuphathelene nobudala nokuthinta kwe-laronidase kubantwana abaneminyaka engaphansi kwengu-5. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ngokuphathelene nobudala nokuthinta kwe-laronidase azikwenziwanga kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma kusetshenziswa leliyeza ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha leliyeza ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Tshela udokotela wakho uma uthatha noma iyiphi enye imithi yokubhalwa noma engabhalwanga (over-the-counter [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukusebenzisana. Xoxa nodokotela wakho ngokusebenzisa imithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwaleliyeza. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Umshula wesibeletho noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka ngalolu hlobo lolwemi. Lolu hlobo lolwemi lunikezwa ngenhlanzi ebekwe kwenye yezinsizi zakho. Ungase futhi unikezwe eminye imithi ukuze ugcine ungabi nobumbane noma ukuvimbela ukusabela okungafani ngaphambi kokuthola ukugonywa.