Larotrectinib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Vitrakvi
Mayelana naleli khambi
ILarotrectinib isetshenziswa ekwelapheni iziphumu eziqinile (umdlavuza) ezibangelwa yi-NTRK genes ethile engalungile futhi eseisakazeke noma uma ukuhlinzwa kokususa umdlavuza kungenzeka kube nemiphumela emibi kakhulu, futhi ayikho indlela yokwelapha efanelekile noma umdlavuza ukhulile noma usakazeke ngezinye izindlela zokwelapha. Udokotela wakho uzokwenza ivivi ukuqinisekisa ukuthi leli yona imithi efanele wena. I-Larotrectinib iyingxenye yeqembu lemithi ebizwa ngokuthi yi-antineoplastics (imithi yomdlavuza). Isebenza ngokuphazamisa ukukhula kwamaselula omdlavuza, awohloka ekugcineni. Lona umuthi utholakala kuphela ngesikripthi sodokotela wakho. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluhlukile noma ukusabela okungokwe-alerji kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokungezwani, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube yimanje azibonisi izinkinga ezikhethekile zezingane ezingalimi ukusetshenziswa kwe-larotrectinib ezinganeni. Ukuphepha kanye nokusebenza kahle kuye kwaqiniswa. Izifundo ezifanele ezenziwe kuze kube yimanje azibonisi izinkinga ezikhethekile zabantu abadala ezingalimi ukusetshenziswa kwe-larotrectinib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Uma uthatha le mithi, kubaluleke kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlongozwayo ngezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akuyona into enconywayo, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungabangela ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akuyona into enconywayo, kodwa kungase kungakhuphuki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi i-anticancer inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokusebenzisa le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukusebenzisana eduze nodokotela wakho phakathi nokuphathwa kwakho. Thatha le mithi kuphela njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Le mithi iza nepheshana lolwazi lwabaguli nemiyalo yabaguli. Funda futhi ulandele le miyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Gwinya ikhaphsuli yonke ngamanzi. Ungayikhili, ungayiqhekeza, noma uyivule. Ungayithatha le mithi ngokudla noma ngaphandle kokudla. Linganisa i-oral liquid ngesipuni sokuthakatha esiphawuliwe, isirinji yomlomo, noma indebe yemithi. Isipuni sendlu esivamile singase singabi nesilinganiso esifanele se-liquid. Ukusebenzisa i-oral liquid: Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mithi. Inani lemithi elizothathwa lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani avamile ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi olithathayo lixhomeke emandleni emithi. Futhi, inani lezinye olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezinye, nobude besikhathi olithatha khona imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yisilinganiso sale mithi, yithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sesilinganiso sakho esilandelayo, susa isilinganiso esiphuthelwe bese ubuyela esikhathini sakho sokuthola imithi. Ungawandisi ama-doses. Uma isilinganiso sakho esilandelayo siyi-6 amahora noma ngaphansi, susa isilinganiso esiphuthelwe bese ubuyela esikhathini sakho sokuthola imithi. Uma uhlanza ngemuva kokuthatha isilinganiso, thatha isilinganiso esilandelayo ngesikhathi esivamile. Gcina kubantwana. Ungagcini imithi eliphelile noma imithi engasadingeki. Buza ochwepheshe bezempilo ukuthi kufanele ulahle kanjani noma iyiphi imithi ongayisebenzisi. Gcina imithi embizeni evaliwe emazingeni okushisa kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayifrizi. Gcina i-oral liquid esihlalweni. Ungayifrizi. Lahla noma iyiphi i-oral liquid engasetshenzisiwe embizeni yama-milliliters angu-100 (mL) ngemuva kwezinsuku ezingu-90 ne-oral liquid embizeni yama-milliliters angu-50 ngemuva kwezinsuku ezingu-31 zokuqala ukuvula ibhodlela.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.