Yini i-Levomilnacipran: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Levomilnacipran iyisidambisi sokucindezeleka esinikezwa ngudokotela esisiza ukulinganisa amakhemikhali obuchopho ukuze kuthuthukiswe imizwa futhi kuncishiswe izimpawu zokucindezeleka. Ingowesigaba semithi ebizwa ngokuthi ama-serotonin-norepinephrine reuptake inhibitors (SNRIs), esebenza ngokwandisa amazinga ama-neurotransmitters amabili abalulekile ebuchosheni bakho. Le mithi yenzelwe ngqo ukusiza abantu abangatholanga ukukhululeka ngeminye imithi yokucindezeleka noma abadinga indlela ehlukile yokuphatha ukucindezeleka kwabo.

Yini i-Levomilnacipran?

I-Levomilnacipran iyisidambisi sokucindezeleka esisha esiqondisa amakhemikhali amabili obuchopho ngesikhathi esisodwa. Ngokungafani neminye imithi yokucindezeleka endala egxila ku-neurotransmitter eyodwa nje, le mithi isebenza kokubili i-serotonin ne-norepinephrine ukusiza ukubuyisela ibhalansi yamakhemikhali ebuchosheni bakho. Yifomu elisebenzayo le-milnacipran, okusho ukuthi ihlanzekile ukuze isebenze kahle kakhulu ngemiphumela emincane engaba khona.

Le mithi iza ngama-capsules akhishwe isikhathi eside akhulula kancane umuthi usuku lonke. Ifomula yokukhishwa isikhathi eside isiza ukugcina amazinga aqinile ohlelweni lwakho, okunganciphisa imiphumela emibi futhi kuthuthukise ukuthi umuthi usebenza kahle kangakanani kuwe.

Isetshenziselwani i-Levomilnacipran?

I-Levomilnacipran ikakhulukazi inikezwa ukwelapha ukuphazamiseka okukhulu kokucindezeleka kubantu abadala. Udokotela wakho angase ancome le mithi uma uhlangabezana nemizwa eqhubekayo yokudabuka, ukungabi nathemba, noma ukulahlekelwa intshisekelo emisebenzini obuyijabulela ngaphambili. Ilusizo ikakhulukazi kubantu abangazange basabele kahle kweminye imithi yokucindezeleka noma abadinga umuthi obhekana nemizwa namazinga wamandla.

Ngezinye izikhathi odokotela banikeza i-levomilnacipran ezinye izimo, nakuba lokhu kungavamile. Lokhu kusetshenziswa okungahambisani nelebula kungabandakanya izinhlobo ezithile zobuhlungu obungapheli noma i-fibromyalgia, njengoba imiphumela yomuthi ku-norepinephrine ingasiza ekuphathweni kobuhlungu. Kodwa-ke, udokotela wakho uzohlala ekala izinzuzo nezingozi ngaphambi kokuyinikeza ngezimo ezingezona ukucindezeleka.

Isebenza Kanjani I-Levomilnacipran?

I-Levomilnacipran isebenza ngokuvimba ukuthathwa kabusha kwe-serotonin ne-norepinephrine ebuchosheni bakho. Cabanga ngayo njengokusiza la makhemikhali abalulekile alawula imizwa ahlale esebenza isikhathi eside ezikhaleni eziphakathi kwamaseli ezinzwa. Lokhu kwanda kokutholakala kwama-neurotransmitters kungasiza ekuthuthukiseni ukuxhumana phakathi kwamaseli obuchopho futhi kancane kancane kuthuthukise imizwa yakho.

Lo muthi ubhekwa njengomuthi oqinile phakathi kwemithi yokucindezeleka. Inamandla kunezinye izidakamizwa ezindala kodwa ngokuvamile iyabekezeleleka uma isetshenziswa ngendlela efanele. Indlela yokusebenza kabili yokugxila kokubili i-serotonin ne-norepinephrine yenza kube ngempumelelo kubantu abadinga ukusekelwa kwemizwa okubanzi.

Ngeke uzizwele imiphumela ephelele ngokushesha. Abantu abaningi baqala ukuqaphela ukuthuthuka kwemizwa yabo namazinga amandla ngemva kwamasonto angu-2-4 okusetshenziswa okuqhubekayo, nakuba abanye bengase badinge amasonto angu-6-8 ukuze bathole izinzuzo eziphelele.

Kufanele Ngiyithathe Kanjani I-Levomilnacipran?

Thatha i-levomilnacipran ngendlela enqunywe ngayo udokotela wakho, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha ngokudla noma ngaphandle kokudla, kodwa ukuyithatha ngokudla kungasiza ekunciphiseni isisu uma uhlangabezana nanoma yini. Gwinya ikhaphule ngokuphelele ngamanzi futhi ungayichobozi, uyihlafune, noma uyivule, njengoba lokhu kungathinta indlela umuthi okhululwa ngayo emzimbeni wakho.

Odokotela abaningi baqala iziguli ngomthamo ophansi bese bewukhulisa kancane kancane ngokuhamba kwesikhathi. Le ndlela isiza umzimba wakho ukuthi ujwayele imithi futhi inciphisa amathuba okuba nemiphumela emibi. Ungayeki ukuthatha i-levomilnacipran ngokuzumayo, ngisho noma uzizwa ungcono, ngoba lokhu kungabangela izimpawu zokuhoxisa.

Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinye izindlela. Amaphilisi akhishwa kancane kancane angavulwa futhi afafazwe ku-applesauce uma kudingeka, kodwa lokhu kufanele kwenziwe ngaphansi kokuqondiswa kwezokwelapha kuphela.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Levomilnacipran?

Abantu abaningi badinga ukuthatha i-levomilnacipran izinyanga eziningana ukuze bagcine imizwa yabo ethuthukisiwe futhi bavimbele ukucindezeleka ukuthi kubuye. Udokotela wakho ngokuvamile uzoncoma ukuqhubeka nomuthi okungenani izinyanga eziyi-6-12 ngemuva kokuthi izimpawu zakho zithuthuke. Abanye abantu bangase badinge ukwelashwa isikhathi eside, ikakhulukazi uma beke baba neziqephu eziningi zokucindezeleka.

Isinqumo sokuthi uhlale isikhathi esingakanani ku-levomilnacipran sincike ezintweni eziningana. Lokhu kufaka phakathi ukuthi usabela kahle kangakanani emuthini, ukuthi wake waba nokucindezeleka ngaphambili, kanye nesimo sakho sempilo esiphelele. Udokotela wakho uzosebenza nawe ukuthola ubude obufanele obulinganisela ukusebenza kahle nezidingo zakho zomuntu siqu nezintandokazi zakho.

Yiziphi Imiphumela Emibi Ye-Levomilnacipran?

Njengayo yonke imithi, i-levomilnacipran ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela eminingi emibi ithambile futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala.

Nawa amanye imiphumela emibi ejwayelekile ongase uyithole:

• Isicanucanu nokukhathazeka kwesisu
• Ikhanda
• Isiyezi
• Umlomo owomile
• Ukuqunjelwa
• Ukujuluka okwandayo
• Ubunzima bokulala
• Ukuncipha kwesifiso sokudla
• Ukukhathala

Lezi zimo ezingezinhle ngokuvamile ziba zesikhashana futhi ziyalawuleka. Ukuthatha umuthi ngesikhathi sokudla kungasiza ngesicanucanu, futhi ukuhlala unamanzi kunganciphisa umlomo owomile nokuqunjelwa.

Abanye abantu bangase babe nemiphumela engavamile kodwa ekhathazayo edinga ukunakekelwa kwezokwelapha:

• Ushintsho olukhulu emfutheni wegazi
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ushintsho olukhulu emizweni noma imicabango yokuzibulala
• Ukuphuma kwegazi okungavamile noma ukuqubuka
• Ubunzima bokuchama
• Ukuphendula okukhulu komzimba

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi zale miphumela emibi kakhulu. Bangasiza ekutholeni ukuthi ngabe udinga ukulungisa umthamo wakho noma uzame omunye umuthi.

Ubani Ongafanele Athatha I-Levomilnacipran?

I-Levomilnacipran ayifanele wonke umuntu. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha nemithi yamanje ngaphambi kokuyinika ukuze aqinisekise ukuthi iphephile kuwe.

Akufanele uthathe i-levomilnacipran uma njengamanje uthatha noma usanda kuyeka ukuthatha ama-MAOI (ama-monoamine oxidase inhibitors). Le mithi ingasebenzisana ngendlela eyingozi ne-levomilnacipran futhi ibangele isimo esibi esibizwa ngokuthi i-serotonin syndrome.

Abantu abanezimo ezithile zezokwelapha badinga ukucatshangelwa okukhethekile ngaphambi kokuqala i-levomilnacipran:

• Umfutho wegazi ophezulu ongagadiwe
• Izinkinga zesigqi senhliziyo
• Isifo esibi sezinso
• Izinkinga zesibindi
• I-Glaucoma
• Izifo zokuphuma kwegazi
• Umlando wokuhlaselwa
• Isifo se-Bipolar

Uma unezinye zalezi zimo, akusho ukuthi awukwazi ukuthatha i-levomilnacipran, kodwa udokotela wakho uzodinga ukukuqapha eduze futhi mhlawumbe alungise uhlelo lwakho lokwelashwa.

Amagama Omkhiqizo we-Levomilnacipran

I-Levomilnacipran itholakala ngaphansi kwegama lomkhiqizo elithi Fetzima e-United States. Le yindlela ejwayelekile ozoyithola emakhemisi, futhi iza ngamandla ahlukene amaphilisi akhishwe isikhathi eside.

Izinhlobo ezivamile ze-levomilnacipran zingase zitholakale esikhathini esizayo, kodwa okwamanje, i-Fetzima iyigama lomkhiqizo eliyinhloko elitholakalayo. Umshwalense wakho kanye nekhemisi kungase kuthinte ukuthi iyiphi inguqulo oyitholayo, ngakho-ke kufanelekile ukuxoxa ngezinketho nodokotela wakho kanye nosokhemisi.

Ezinye izindlela ze-Levomilnacipran

Uma i-levomilnacipran ingasebenzi kahle kuwe noma idala imiphumela engathandeki, imithi eminingi ehlukile ingase ilungele. Udokotela wakho angakusiza ukuthi uhlole ezinye izinketho ngokusekelwe ezidingweni zakho ezithile kanye nomlando wakho wezokwelapha.

Ezinye izidambisi zokucindezeleka ze-SNRI ezisebenza ngendlela efanayo zihlanganisa:

• I-Venlafaxine (Effexor)
• I-Duloxetine (Cymbalta)
• I-Desvenlafaxine (Pristiq)

Udokotela wakho angase futhi acabangele izidambisi zokucindezeleka ze-SSRI, ezigxila kakhulu ku-serotonin, noma ezinye izinhlobo zezidambisi zokucindezeleka kuye ngezimpawu zakho nokuphendula ekwelashweni. Umuthi ngamunye unenzuzo yawo kanye nemiphumela engaba khona, ngakho-ke ukuthola okulungile ngokuvamile kudinga ukubekezela nokuxhumana nethimba lakho lezempilo.

Ingabe i-Levomilnacipran ingcono kune-Duloxetine?

Kokubili i-levomilnacipran ne-duloxetine ziyizidambisi zokucindezeleka ze-SNRI ezisebenzayo, kodwa zisebenza kancane kancane futhi zingase zilingane abantu abahlukene kangcono. I-Levomilnacipran ivame ukuba nomthelela olinganiselayo ku-serotonin ne-norepinephrine, kuyilapho i-duloxetine inethonya eliqinile ku-serotonin.

Ukukhetha okungcono kuncike ekuphenduleni kwakho komuntu ngamunye, ukubekezelela imiphumela emibi, nezimpawu ezithile. Abanye abantu bathola ukuthi i-levomilnacipran idala imiphumela emibi emincane yezocansi noma ukukhuluphala uma kuqhathaniswa ne-duloxetine, kanti abanye bangase bakhethe izinzuzo ezengeziwe ze-duloxetine zokuphatha ubuhlungu.

Udktela wakho uzocabangela izinto ezinjengomlando wakho wezokwelapha, eminye imithi oyithathayo, nezimpawu zakho ezithile zokucindezeleka lapho ekhetha phakathi kwalezi zinketho. Okusebenza kahle kumuntu oyedwa kungase kungabi yindlela ekahle komunye.

Imibuzo Evame Ukubuzwa Mayelana ne-Levomilnacipran

Q1. Ingabe i-Levomilnacipran iphephile ezinkingeni zenhliziyo?

I-Levomilnacipran ingathinta umfutho wegazi nesivinini senhliziyo, ngakho-ke abantu abanezifo zenhliziyo badinga ukuqashwa ngokucophelela. Udktela wakho uzohlola impilo yakho yenhliziyo ngaphambi kokukuyala lo muthi futhi angase ancome ukuhlolwa komfutho wegazi njalo ngesikhathi sokwelashwa. Uma unezifo zenhliziyo ezilawulwa kahle, ungase ukwazi ukuthatha i-levomilnacipran ngaphansi kokuqashwa okufanele kwezokwelapha.

Q2. Kufanele ngenzeni uma ngithatha i-Levomilnacipran eningi ngengozi?

Uma ngengozi uthatha i-levomilnacipran eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukweqisa kungabangela izimpawu ezinzima njengokushaya kwenhliziyo okusheshayo, umfutho wegazi ophezulu, isicanucanu, ukuhlanza, nokudideka. Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini - funa usizo lwezokwelapha ngokushesha. Gcina ibhodlela lomuthi unawo lapho ufuna usizo ukuze abahlinzeki bezempilo bazi kahle ukuthi uthathe ini nokuthi uthathe malini.

Q3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Levomilnacipran?

Uma uphuthelwa umthamo we-levomilnacipran, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze nesikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi. Ukusetha isikhumbuzi sansuku zonke ocingweni lwakho kungakusiza ukuthi ukhumbule ukuthatha imithi yakho ngokuqhubekayo.

Q4. Ngingayeka nini ukuthatha i-Levomilnacipran?

Ungayeki ukuthatha i-levomilnacipran ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungadala izimpawu zokuhoxisa njengokugajuka, isicanucanu, ikhanda elibuhlungu, kanye nezinguquko zemizwa. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo wakho emasontweni amaningana noma izinyanga uma sekuyisikhathi sokuyeka. Le nqubo yokunciphisa iyasiza ekunciphiseni izimpawu zokuhoxisa futhi inciphisa ingozi yokuthi ukucindezeleka kwakho kubuye.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Levomilnacipran?

Kungcono ukugwema noma ukukhawulela utshwala ngenkathi uthatha i-levomilnacipran. Utshwala bungakhuphula imiphumela yokuthulisa yomuthi futhi kungase kwenze izimpawu zokucindezeleka zibe zimbi. Uma ukhetha ukuphuza ngezikhathi ezithile, xoxa ngalokhu nodokotela wakho kuqala futhi uqaphele ukuthi utshwala bungakwenza uzizwe ukozela noma unesiyezi kunokujwayelekile. Khumbula ukuthi utshwala bungaphazamisa nokulala kwakho nemizwa yakho, okungase kuphikisane nezinzuzo ze-antidepressant yakho.