Yini i-Levothyroxine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Levothyroxine iyihomoni yokwenziwa yegilo ethatha indawo noma inezele i-homoni yemvelo ekhiqizwa yigland yakho yegilo. Uma igilo lakho lingakhiqizi i-homoni eyanele ngokwalo, i-levothyroxine ingena ukusiza umzimba wakho ukuthi ugcine ukusebenza kahle komzimba, amazinga wamandla, nempilo yonke. Lo muthi ungomunye wemithi evame ukunqunywa emhlabeni wonke futhi usize izigidi zabantu ukuthi bazizwe sengathi bangabona babo futhi.

Yini i-Levothyroxine?

I-Levothyroxine empeleni iyinguqulo eyenziwe ngumuntu ye-thyroxine, eyaziwa nangokuthi i-T4, okuyihomoni eyinhloko ekhiqizwa ngokwemvelo yigland yakho yegilo. Igland yakho yegilo, etholakala entanyeni yakho, isebenza njengesikhungo sokulawula ukusebenza komzimba wakho. Uma ingakhiqizi i-homoni eyanele, yonke indlela yakho ingancipha, ithinte yonke into kusukela emazingeni akho wamandla kuya ezingeni lokushaya kwenhliziyo yakho.

Inguqulo yokwenziwa ku-levothyroxine ifana ngamakhemikhali naleyo umzimba wakho oyenza ngokwemvelo. Lokhu kusho ukuthi umzimba wakho ungayisebenzisa ngempumelelo njengehomoni yakho yegilo. Cabanga ngayo njengokunikeza umzimba wakho uphethiloli owudingayo ukuze usebenze ngejubane elifanele uma igilo lakho lingakwazi ukuhambisana nesidingo.

Isetshenziselwani i-Levothyroxine?

I-Levothyroxine ikakhulukazi iphatha i-hypothyroidism, isimo lapho igland yakho yegilo ingakhiqizi i-homoni eyanele. Lokhu kwenzeka kaningi kunokuba ungacabanga, kuthinta cishe u-5% wabantu, nabesifazane benamathuba amahlanu kuya kwayisishiyagalombili okuthi bathuthukise lesi simo kunamadoda.

Ngaphandle kwe-hypothyroidism, odokotela banquma i-levothyroxine ngezimo eziningana ezihlobene negilo. Nakhu ukusetshenziswa okuyinhloko umhlinzeki wakho wezempilo angase akutuse ngakho:

• I-Hashimoto's thyroiditis, isimo se-autoimmune esilimaza kancane kancane i-thyroid yakho
• Ukwelashwa komdlavuza we-thyroid, ngokuvamile ngemva kokususwa kwe-thyroid ngemva kokuhlinzwa
• Ukuvimbela nokwelashwa kwe-goiter, lapho i-thyroid ekhulisiwe idinga ukucindezelwa kwamahomoni
• Ukufakwa kwamahomoni e-thyroid ngemva kokuhlinzwa kwe-thyroid
• I-hypothyroidism ezelwe ngaphandle kokuzalwa ngaphandle kwe-thyroid esebenza kahle

Kwezinye izimo, odokotela bangase banikeze i-levothyroxine ye-subclinical hypothyroidism, lapho amazinga akho e-hormone ye-thyroid ephansi kodwa uba nezimpawu. Udokotela wakho uzohlola ngokucophelela ukuthi ukwelashwa kulungile yini esimweni sakho esithile.

Isebenza Kanjani I-Levothyroxine?

I-Levothyroxine isebenza ngokufaka esikhundleni se-hormone ye-thyroid umzimba wakho ongayikhiqizi ngokwanele ngokwemvelo. Uma uyithatha, umzimba wakho uguqula ingxenye ye-levothyroxine ibe yifomu elisebenzayo kakhulu elibizwa nge-T3, elithinta ngokuqondile amaseli akho kanye nokukhula komzimba.

Lo muthi uthathwa njengokwelashwa okuqinile nokuthembekile ngoba unikeza amazinga e-hormone aqhubekayo, aqhubekayo uma ethathwa ngendlela efanele. Ngokungafani neminye imithi esebenza ngokushesha, i-levothyroxine ithatha isikhathi ukwakheka ohlelweni lwakho futhi ibonise imiphumela yayo ephelele. Abantu abaningi baqala ukuzizwa ngcono phakathi kwamasonto angu-4-6 ekuqaleni kokwelashwa, nakuba ezinye izithuthukisi zingase zibonwe ngokushesha.

Umzimba wakho usebenzisa le hormone ukulawula cishe yonke imetabolism yeseli. Uma amazinga ebuyiselwa kokujwayelekile, amandla akho abuya, izinga lokushaya kwenhliziyo yakho lijwayeleka, nezinye izimpawu ze-hypothyroidism zithuthuka kancane kancane. Umuthi empeleni usiza umzimba wakho ukuthi usebenze sengathi i-thyroid yakho isebenza ngendlela ejwayelekile futhi.

Kufanele Ngiyithathe Kanjani I-Levothyroxine?

Ukuphuza i-levothyroxine ngendlela efanele kubalulekile ukuze isebenze kahle. Isikhathi nendlela yokuthatha lo muthi kungathinta kakhulu ukuthi umzimba wakho uyawumunca kanjani, ngakho ukulandela imihlahlandlela ngokucophelela kwenza umehluko omkhulu endleleni ozizwa ngayo.

Phuza i-levothyroxine esiswini esingenalutho, okungcono imizuzu engama-30-60 ngaphambi kokudla kwasekuseni noma ngesikhathi sokulala, okungenani amahora ama-3-4 ngemuva kokudla kwakho kokugcina. Lokhu kuqinisekisa ukumuncwa okuphezulu ngoba ukudla, ikakhulukazi ukudla okunefayibha ephezulu, i-calcium, nensimbi, kungaphazamisa ukuthi umzimba wakho usebenzisa malini umuthi.

Amanzi ayisinqumo esingcono kakhulu sokuthatha i-levothyroxine. Gwema ukuyithatha nekhofi, ubisi, noma ezinye iziphuzo, ngoba lezi zinganciphisa ukumuncwa. Uma ukhetha ukuyithatha ngesikhathi sokulala, qiniseka ukuthi awukadli lutho okungenani amahora ama-3-4 ngaphambi kwalokho.

Ukuqina kubalulekile nge-levothyroxine. Yithathe ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga e-hormone aqinile emzimbeni wakho. Abantu abaningi bathola ukuthi ukusetha i-alamu yansuku zonke kubasiza ukuthi bakhumbule, ikakhulukazi emasontweni ambalwa okuqala okwelashwa.

Uma udinga ukuthatha eminye imithi noma izithasiselo, ukwahlukanisa lezi ku-levothyroxine kubalulekile. Izithasiselo ze-calcium, insimbi, ama-antacid, neminye imithi ethile kufanele ithathwe okungenani amahora ama-4 ngaphandle kwe-levothyroxine ukuvimbela ukuxhumana.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Levothyroxine?

Abantu abaningi abane-hypothyroidism badinga ukuthatha i-levothyroxine impilo yabo yonke. Lokhu akunjalo ngoba umuthi uyalutha, kodwa ngoba isimo esibangela ukuthi i-thyroid yakho ingasebenzi kahle ngokuvamile asizixazululi ngokwazo.

Nokho, kunezinye izimo lapho ukwelashwa kungase kube okwesikhashana. Uma i-hypothyroidism yakho yabangelwa imithi ethile, i-postpartum thyroiditis, noma ezinye izinhlobo zokuvuvukala kwe-thyroid, udokotela wakho angase agcine ezama ukunciphisa noma ukuyeka umuthi ukuze abone ukuthi umsebenzi wakho we-thyroid ululame yini.

Udktela wakho uzoqapha ukusebenza komdlavuza wakho ngemivivinyo yegazi ejwayelekile, ngokuvamile njalo ezinyangeni eziyi-6-12 uma umthamo wakho uzinzile. Le mivivinyo isiza ukuqinisekisa ukuthi uthola umthamo ofanele womuthi nokuthi amazinga omdlavuza wakho ahlala elungile empilweni yakho.

Ungayeki ukuthatha i-levothyroxine ngokuzumayo ngaphandle kokuxoxa ngayo nomhlinzeki wakho wezempilo. Umzimba wakho uthembele kulokhu kushintshwa kwamahomoni, futhi ukuyeka kungazelelwe kungabangela ukuthi izimpawu zakho ze-hypothyroidism zibuye, ngezinye izikhathi zibe zimbi kakhulu kunakuqala.

Ziyini Imiphumela Eceleni ye-Levothyroxine?

Uma ithathwa ngomthamo ofanele, i-levothyroxine ngokuvamile ibangela imiphumela emincane kakhulu eceleni ngoba imane ithatha indawo yalokho okufanele umzimba wakho ukwenze ngokwemvelo. Imiphumela eminingi eceleni yenzeka lapho umthamo uphezulu kakhulu, empeleni idala isimo se-hyperthyroid sesikhashana.

Nawa amanye imiphumela eceleni ongase uyithole, ikakhulukazi uma uqala ukwelashwa noma ulungisa imithamo:

• Ukushaya kwenhliziyo okusheshayo noma ukushaya kwenhliziyo okusheshayo
• Ukuzizwa ukhathazekile, unovalo, noma ungakhululekile
• Ukulala kanzima noma ukuzizwa unamandla ngokweqile
• Ukukhuphuka kwesifiso sokudla ngaphandle kokuzuza isisindo
• Ukuthuthumela okuncane ezandleni zakho
• Ukuzizwa ufudumele kakhulu noma ukujuluka kakhulu kunokujwayelekile
• Ukulahlekelwa izinwele okwesikhashana ezinyangeni ezimbalwa zokuqala zokwelashwa

Lezi zimpawu ngokuvamile ziyathuthuka njengoba umzimba wakho ujwayela umuthi noma lapho udokotela wakho elungisa umthamo wakho. Abantu abaningi bathola ukuthi noma yimiphi imiphumela yokuqala eceleni iyancipha emasontweni ambalwa.

Imiphumela emibi kakhulu ayivamile kodwa idinga ukunakekelwa kwezokwelapha ngokushesha. Xhumana nodokotela wakho ngokushesha uma uzwa ubuhlungu besifuba, ukushaya kwenhliziyo okukhulu, ukukhathala ukuphefumula, noma izimpawu zokungezwani komzimba nezinto ezithile njengokuqubuka, ukuvuvukala, noma ukugwinya kanzima.

Abanye abantu bakhathazeka ngemiphumela yesikhathi eside, kodwa iminyaka eminingi yocwaningo ikhombisa ukuthi i-levothyroxine elinganiswe kahle iphephile kakhulu ukusetshenziswa isikhathi eside. Izinzuzo zokwelapha i-hypothyroidism zidlula kakhulu izingozi ezincane lapho imithi isetshenziswa ngendlela efanele.

Ubani Ongafanele Athatha I-Levothyroxine?

I-Levothyroxine ngokuvamile iphephile kubantu abaningi, kodwa izimo ezithile zidinga ukuqapha okwengeziwe noma zingenza lo muthi ungafaneleki. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwubhala.

Abantu abane-adrenal insufficiency engelashwa akufanele bathathe i-levothyroxine kuze kube yilapho isimo sabo se-adrenal silawulwa kahle. Ukuthatha i-hormone yegilo lapho amagilo akho e-adrenal engasebenzi kahle kungase kubhebhethekise i-adrenal crisis, isimo esingase sibeke ukuphila engozini.

Uma unezimo ezithile zenhliziyo, udokotela wakho kungase kudingeke akuqale ngomthamo ophansi futhi akuqaphe eduze. Lokhu kuhlanganisa abantu abanesifo semithambo yenhliziyo, ukuhluleka kwenhliziyo, noma umlando wokuhlaselwa yinhliziyo. Umuthi ungakhuphula izinga lokushaya kwenhliziyo nomsebenzi enhliziyweni yakho.

Nawa amanye amazinga lapho i-levothyroxine idinga ukucatshangelwa okukhethekile:

• Ukukhulelwa nokuncelisa (ngokuvamile kuphephile kodwa kudinga ukulungiswa komthamo)
• Iziguli ezigugile, ikakhulukazi labo abaneminyaka engaphezu kwengama-65 abanezimo zenhliziyo
• Abantu abanesifo sikashukela, njengoba i-hormone yegilo ingathinta amazinga kashukela egazini
• Labo abane-osteoporosis, njengoba i-hormone yegilo engaphezulu ingathinta ukuminyana kwamathambo
• Abantu abanezifo zokuthuthumela, njengoba i-hormone yegilo inganciphisa umkhawulo wokuthuthumela

Uma unezimo ezithile, ungakhathazeki - akusho ngempela ukuthi awukwazi ukuthatha i-levothyroxine. Udokotela wakho uzosebenza nawe ukuthola indlela ephephe kakhulu futhi angase aqale ngomthamo ophansi noma akuqaphe njalo.

Amagama Omkhiqizo we-Levothyroxine

I-Levothyroxine itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Synthroid iyona eyaziwa kakhulu. Ezinye izinhlobo ezivamile zihlanganisa i-Levoxyl, i-Tirosint, ne-Unithroid, ngalinye linokwakheka okuhlukile kancane kodwa liqukethe isithako esifanayo esisebenzayo.

Abantu abaningi benza kahle nge-levothyroxine ejwayelekile, engabizi kakhulu kunezinhlobo ezinamagama omkhiqizo. Kodwa-ke, abanye abantu bathola ukuthi bazizwa kangcono ngomkhiqizo othile ngenxa yomehluko wezithako ezingasebenzi noma izinqubo zokukhiqiza.

Uma njengamanje usebenzisa inguqulo enegama lomkhiqizo, ungangeni ku-generic (noma okuphambene nalokho) ngaphandle kokubonisana nodokotela wakho. Noma ngabe ziqukethe isithako esifanayo esisebenzayo, umzimba wakho ungase uzithathe ngendlela ehlukile kancane, okudinga ukulungiswa komthamo.

I-Tirosint iyindlela entsha eza ngama-gel caps futhi iqukethe izithako ezingasebenzi ezimbalwa. Abanye abantu abanobunzima ngamaphilisi endabuko ngenxa yokungezwani komzimba noma izinkinga zokumunca bangazuza kulolu hlobo.

Ezinye izindlela ze-Levothyroxine

Ngenkathi i-levothyroxine iyindinganiso yegolide yokwelapha i-hypothyroidism, kunezindlela ezimbalwa ezitholakalayo kubantu abangayiphenduli kahle noma abanezidingo ezithile zezokwelapha.

I-thyroid yemvelo eyomile (NDT), ethengiswa ngaphansi kwamagama omkhiqizo afana ne-Armour Thyroid ne-Nature-Throid, iqukethe ama-hormone womabili i-T4 ne-T3 akhishwe ezinqeni ze-pig thyroid. Abanye abantu bazizwa bengcono ku-NDT, yize ubufakazi besayensi bungabonisi ngokusobala ukuthi iphakeme kune-levothyroxine ezigulini eziningi.

I-T3 yokwenziwa (liothyronine) ngezinye izikhathi i-odwa yodwa noma ihlanganiswe ne-levothyroxine. Lokhu kuvame ukugcinelwa abantu abanobunzima bokuguqula i-T4 ibe yi-T3 emzimbeni wabo, yize lokhu kungavamile.

Ukwelashwa okuhlanganisiwe kusetshenziswa kokubili i-levothyroxine ne-liothyronine enye indlela abanye odokotela abayicabangayo. Ucwaningo lwamanje luphakamisa ukuthi le ndlela ingasiza iqembu elincane leziguli ezingazizwa kahle ngokuphelele nge-levothyroxine yodwa.

Odokotela abaningi be-endocrinologists basathanda i-levothyroxine njengendlela yokwelapha yokuqala ngoba ifundwe kahle, iyabikezeleka, futhi iyasebenza enanini elikhulu leziguli. Uma ungazizwa kahle nge-levothyroxine, khuluma nodokotela wakho mayelana nokuthuthukisa umthamo wakho wamanje ngaphambi kokucabangela ezinye izindlela.

Ingabe i-Levothyroxine Ingcono Kune-Synthroid?

I-Levothyroxine ne-Synthroid ziqukethe isithako esifanayo esisebenzayo - i-levothyroxine sodium. I-Synthroid imane nje igama lomkhiqizo le-levothyroxine, ngakho-ke empeleni imithi efanayo enemiphumela efanayo yokwelapha.

Umehluko omkhulu ulele ezithakweni ezingasebenzi kanye nezinqubo zokukhiqiza. I-Synthroid isinesikhathi eside futhi inemininingwane eminingi yomtholampilo, yingakho odokotela abathile beyithanda. Kodwa-ke, i-levothyroxine ejwayelekile ivunywe yi-FDA futhi iyalingana ne-bioequivalent ne-Synthroid, okusho ukuthi kufanele isebenze ngempumelelo.

Abanye abantu babika ukuzizwa ngcono nge-Synthroid uma kuqhathaniswa ne-levothyroxine ejwayelekile, kanti abanye ababoni mehluko nakancane. Lokhu kuhluka komuntu ngamunye kungase kube ngenxa yomehluko endleleni umzimba wakho oqhubula ngayo izithako ezingasebenzi noma ukwehluka okuncane ekukhiqizeni.

Izindleko zivame ukuba yisici esibalulekile esinqumweni. I-levothyroxine ejwayelekile ngokuvamile ibiza kancane kune-Synthroid, okwenza itholakale kalula ekwelashweni kwesikhathi eside. Uma wenza kahle nge-levothyroxine ejwayelekile, ngokuvamile akukho sizathu sezokwelapha sokushintshela egameni lomkhiqizo.

Uma ucabangela ukushintsha phakathi kwezinhlobo ezijwayelekile nezegama lomkhiqizo, xoxa ngalokhu nodokotela wakho kuqala. Bangase bafune ukuhlola kabusha amazinga akho e-thyroid ngemuva kwamasonto angu-6-8 nganoma yiluphi ushintsho ukuze baqinisekise ukuthi amazinga akho e-hormone ahlala elungile.

Imibuzo Evame Ukubuzwa Nge-Levothyroxine

Ingabe i-Levothyroxine Iphephile Esimeni Senhliziyo?

I-Levothyroxine ingaba yingozi kubantu abanezifo zenhliziyo, kodwa idinga ukugadwa ngokucophelela kwezokwelapha. Udokotela wakho cishe uzoqala ngomthamo ophansi bese ewunyusa kancane kancane ukuze agweme ukubeka ingcindezi eyengeziwe enhliziyweni yakho.

I-hypothyroidism engelashwanga ingenza ngempela izifo zenhliziyo zibe zimbi ngokunyusa amazinga e-cholesterol nokunciphisa ukusebenza kwenhliziyo. Uma ilashwa ngendlela efanele, i-levothyroxine ivame ukuthuthukisa impilo yenhliziyo ngokubuyisela umzimba ojwayelekile futhi kunciphise izici eziyingozi zemithambo yenhliziyo.

Uma unezifo zenhliziyo, udokotela wakho uzokugada eduze ngesikhathi sokwelashwa, mhlawumbe ngezivivinyo zegazi ezivamile nokugadwa kwenhliziyo. Bazosebenza ukuthola ibhalansi efanele phakathi kokwelapha i-hypothyroidism yakho nokuvikela impilo yenhliziyo yakho.

Kufanele ngenzeni uma ngiphuzile i-Levothyroxine eningi ngengozi?

Uma ngengozi uphuze umthamo owengeziwe we-levothyroxine, ungangeni ekuqhumeni. Umthamo owodwa owengeziwe akunakwenzeka ukuthi ubangele umonakalo omkhulu, kodwa ungase uhlangabezane nezimpawu ezinjengokushaya kwenhliziyo okusheshayo, ukukhathazeka, noma ukuzizwa unovalo usuku olulodwa noma ezimbili.

Xhumana nodokotela wakho noma usokhemisi ukuze uthole isiqondiso, ikakhulukazi uma uphuze okuningi kakhulu kunomthamo wakho obekiwe. Bangakweluleka ukuthi ngabe udinga ukunakekelwa kwezokwelapha nokuthi ungayilungisa kanjani isimiso sakho sokulinganisa.

Ungagxumi umthamo wakho olandelayo ukuze

Uma uphuthelwa umthamo we-levothyroxine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Uma kunjalo, weqa umthamo owuphuthelwe bese uqhubeka neshejuli yakho ejwayelekile - ungathathi imithamo emibili ngesikhathi esisodwa.

Ngenxa yokuthi i-levothyroxine inempilo ende, ukuphuthelwa umthamo owodwa ngezikhathi ezithile ngeke kubangele izinkinga ngokushesha. Kodwa-ke, zama ukugcina ukuqina ngoba ukuthatha imithi njalo kusiza ukugcina amazinga akho e-hormone ezinzile.

Uma uvame ukukhohlwa imithamo, cabanga ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi. Abanye abantu bakuthola kuwusizo ukugcina imithi yabo eceleni kombhede wabo noma umenzi wekhofi njengesikhumbuzi esibonakalayo.

Uma uphuthelwe imithamo eminingana, ungazami ukubamba ngokuthatha amaphilisi engeziwe. Xhumana nodokotela wakho ukuze uthole isiqondiso sokuthi ungaqala kanjani kabusha ishejuli yakho yokuthatha imithi ngokuphepha.

Ngingayeka nini Ukuthatha i-Levothyroxine?

Abantu abaningi abane-hypothyroidism badinga ukwelashwa impilo yonke nge-levothyroxine. Izimo ezibangela i-hypothyroidism, njenge-Hashimoto's thyroiditis noma ukuhlinzwa kwegilo, ngokuvamile azixazululi zodwa.

Kodwa-ke, zikhona izimo lapho udokotela wakho angase acabange ukuyeka ukwelashwa. Lokhu kuhlanganisa izimbangela zesikhashana ze-hypothyroidism njenge-postpartum thyroiditis, imithi ethile, noma ezinye izinhlobo zokuvuvukala kwegilo ezingase zilulame ngokuhamba kwesikhathi.

Udokotela wakho uzokwenza lesi sinqumo ngokusekelwe esimweni sakho esithile, ukuthi uselashwe isikhathi esingakanani, kanye nokuhlolwa kwakho kwamanje komsebenzi we-thyroid. Bangase banciphise kancane umthamo wakho ngenkathi beqapha amazinga akho e-thyroid ukuze babone ukuthi umsebenzi wakho wemvelo we-thyroid ululame yini.

Ungalokothi uyeke ukuthatha i-levothyroxine ngokwakho, ngisho noma uzizwa ungcono. Izimpawu zakho zingase zibuye kancane kancane, futhi ukuyeka kungazelelwe ngezinye izikhathi kungase kubangele ukuthi zibuye ngendlela engaphezu kwaleyo eyayikhona ngaphambi kokwelashwa.

Ngingayithatha i-Levothyroxine Ngesikhathi Ngikhulelwe?

I-Levothyroxine ayiphephile nje kuphela ngesikhathi sokukhulelwa kodwa ivame ukubaluleka empilweni yomama nengane. Ukungasebenzi kahle kwegilo ngesikhathi sokukhulelwa kungandisa ingozi yezinkinga ezinjenge-preeclampsia, ukuzalwa ngaphambi kwesikhathi, nezinkinga zokukhula enganeni.

Abesifazane abaningi badinga ukwandisa umthamo wabo we-levothyroxine ngesikhathi sokukhulelwa ngoba izidingo ze-hormone yegilo zivame ukwanda. Udokotela wakho uzoqapha amazinga akho egilo kaningi ngesikhathi sokukhulelwa futhi alungise umthamo wakho njengoba kudingeka.

Uma uhlela ukukhulelwa noma usanda kufunda ukuthi ukhulelwe, yazisa udokotela wakho ngokushesha. Kungenzeka ukuthi bazofuna ukuhlola amazinga akho egilo futhi bangase bakwandise umthamo wakho ngisho nangaphambi kokuthi izimpawu zivele.

I-Levothyroxine iphephile futhi ngesikhathi sokuncelisa futhi isiza ekuqinisekiseni ukuthi unamandla nempilo edingekayo ukunakekela umntwana wakho omusha. Inani elincane elidlulela obisini alilimazi izinsana ezincelisayo.