Yini i-Liothyronine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Liothyronine iyifomu elenziwe ngamanye le-T3, elinye lama-hormone abalulekile okhiqizwa ngumdlavuza wakho wendlala ngokwemvelo. Inikezwa lapho umdlavuza wakho wendlala ungenzi ama-hormone anele ngokwawo, okusiza ukubuyisela amandla kanye nokusebenza komzimba okudingwa umzimba wakho ukuze usebenze kahle.

Lo muthi usebenza ngokushesha kunezinye izindlela zokwelapha umdlavuza wendlala ngoba unikeza i-hormone esebenzayo i-T3 ngqo emangqamuzaneni akho. Udokotela wakho angase akunikeze yona yedwa noma kanye neminye imithi yomdlavuza wendlala ukukusiza ukuthi uzizwe njengawe futhi.

Yini i-Liothyronine?

I-Liothyronine iyinguqulo eyenziwe ngabantu ye-triiodothyronine (T3), okuyi-hormone yomdlavuza wendlala esebenza kakhulu emzimbeni wakho. Cabanga ngayo njengokunikeza umzimba wakho i-hormone eqondile elahlekile lapho umdlavuza wakho wendlala ungasebenzi kahle.

Ngokungafani ne-levothyroxine (T4), okumele umzimba wakho uyiguqule ibe yi-T3, i-liothyronine isivele isefomini elisebenzayo elingasetshenziswa ngamangqamuzana akho ngokushesha. Lokhu kuyenza ibe usizo ikakhulukazi kubantu abanemizimba yabo enobunzima bokwenza le nguquko ngokwemvelo.

Umuthi uza ngamaphilisi amancane owathatha ngomlomo. Udokotela wakho uzonquma umthamo ofanele ngokuya ngamazinga akho athile e-hormone yomdlavuza wendlala nokuthi usabela kanjani ekwelashweni.

Isetshenziselwani i-Liothyronine?

I-Liothyronine iphatha i-hypothyroidism, isimo lapho umdlavuza wakho wendlala ungaqedi ama-hormone anele. Lokhu kungakushiya uzizwa ukhathele, ubanda, futhi unenkungu engqondweni njengoba ukusebenza komzimba wakho kwehla.

Udokotela wakho angase akunikeze lo muthi uma une-primary hypothyroidism, lapho umdlavuza wakho wendlala ngokwawo ungasebenzi kahle. Iphinde isetshenziswe nge-secondary hypothyroidism, okwenzeka lapho i-pituitary gland yakho ingawuthumeli umyalezo kumdlavuza wakho wendlala ngendlela efanele.

Ngezinye izikhathi odokotela banikeza i-liothyronine kanye ne-levothyroxine kubantu abasazwa izimpawu ngaphandle kwemiphumela ejwayelekile yokuhlolwa kwegazi. Lokhu kwelashwa okuhlanganisiwe kungasiza abanye abantu bazizwe bengcono uma ukwelashwa nge-hormone eyodwa kunganele.

Ezimweni ezingavamile, i-liothyronine isetshenziswa njengengxenye yokwelashwa komdlavuza we-thyroid ukucindezela amazinga e-TSH. Kungase futhi kunikezwe ukucindezeleka okukhulu uma kusetshenziswa ngokucophelela kanye nama-antidepressants, nakuba lokhu kungavamile.

Isebenza Kanjani I-Liothyronine?

I-Liothyronine isebenza ngokushintsha ngokuqondile i-hormone ye-T3 i-thyroid yakho okufanele iyenze. Uma usuyithathile, umuthi uhamba ngegazi lakho uye emangqamuzaneni emzimbeni wakho wonke, lapho usiza ukulawula imetabolism yakho.

Lokhu kuthathwa njengomuthi onamandla we-thyroid ngoba i-T3 isebenza kakhulu kune-T4. Amangqamuzana akho angasebenzisa i-liothyronine ngokushesha ngaphandle kokudinga ukuyiguqula kuqala, yingakho abanye abantu beqaphela imiphumela ngokushesha kunezinye izidakamizwa ze-thyroid.

Le hormone isiza ukulawula ukuthi umzimba wakho usebenzisa ngokushesha kangakanani amandla, ithinta izinga lokushaya kwenhliziyo yakho, futhi ithonya izinga lokushisa lomzimba wakho. Iphinde idlale indima ekusebenzeni kobuchopho, yingakho izinkinga ze-thyroid zingathinta imizwa yakho nokucabanga kwakho.

Ngenxa yokuthi i-liothyronine inamandla futhi isebenza ngokushesha kune-levothyroxine, udokotela wakho ngokuvamile uzoqala ngomthamo ophansi futhi awulungise kancane kancane. Le ndlela eqaphelayo isiza ukugwema izimpawu zokuba ne-hormone ye-thyroid eningi.

Kufanele Ngiyithathe Kanjani I-Liothyronine?

Thatha i-liothyronine esiswini esingenalutho, okungcono imizuzu engama-30 kuya ehora elingu-1 ngaphambi kokudla kwasekuseni. Lokhu kusiza umzimba wakho ukuba umunce umuthi kahle futhi kuqinisekisa ukuthi uthola inzuzo ephelele yomthamo ngamunye.

Gwinya ithebhulethi yonke ngengilazi enkulu yamanzi acacile. Gwema ukuyithatha nekhofi, itiye, noma ezinye iziphuzo ezingase ziphazamise ukumuncwa.

Uma uthatha i-liothyronine izikhathi eziningi ngosuku, hlukanisa imithamo ngokulinganayo usuku lonke njengoba udokotela wakho ekuqondisa. Abanye abantu bayayithatha kabili ngosuku, kanti abanye bangase badinge imithamo emincane emithathu ukuze bagcine amazinga e-hormone ezinzile.

Zama ukuthatha imithi yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga e-hormone ezinzile. Ukusetha izikhumbuzi zocingo kungakusiza ukuthi umise le nqubo, ikakhulukazi emasontweni ambalwa okuqala okwelashwa.

Linda okungenani amahora angu-4 ngemva kokuthatha i-liothyronine ngaphambi kokusebenzisa izithasiselo ze-calcium, insimbi, noma ama-antacid, ngoba lokhu kunganciphisa ukuthi umzimba wakho umunca kangakanani umuthi. Isikhathi esifanayo sisebenza ekudleni okunefayibha ephezulu kanye nemikhiqizo ye-soy.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Liothyronine?

Abantu abaningi abane-hypothyroidism badinga ukuthatha i-liothyronine impilo yabo yonke, njengoba isimo se-thyroid esingaphansi ngokuvamile singazixazululi sodwa. Igland yakho ye-thyroid cishe izoqhubeka idinga ukushintshwa kwe-hormone ukuze igcine imetabolism yakho isebenza ngendlela evamile.

Nokho, umthamo wakho ungashintsha ngokuhamba kwesikhathi ngokusekelwe emiphumeleni yakho yokuhlolwa kwegazi nokuthi uzizwa kanjani. Udokotela wakho uzoqapha amazinga akho e-hormone ye-thyroid njalo futhi alungise imithi yakho njengoba kudingeka ukuze kugcinwe ibhalansi efanelekile.

Abanye abantu bangase bakwazi ukuyeka i-liothyronine uma i-hypothyroidism yabo yabangelwa izinto zesikhashana njengemithi ethile noma ukugula okukhulu. Udokotela wakho uzoqaphela ukuthi lokhu kuyasebenza yini esimweni sakho ngokubheka ngokucophelela.

Uma uthatha i-liothyronine ezinye izimo ezinjengokusekela ukucindezeleka, ubude buzoxhomeka ohlelweni lwakho oluthile lokwelapha. Ungalokothi uyeke ukuthatha lo muthi ngokuzumayo ngaphandle kokuxoxa ngakho nodokotela wakho kuqala.

Yiziphi Imiphumela Eceleni Ye-Liothyronine?

Imiphumela eminingi engemihle ye-liothyronine yenzeka uma uthola i-hormone ye-thyroid eningi kakhulu, empeleni idala isimo se-thyroid esisebenza ngokweqile emzimbeni wakho. Izindaba ezinhle ukuthi ukulungisa umthamo wakho ngokuvamile kulungisa lezi zinkinga.

Nawa amanye imiphumela evamile ongase uhlangabezane nayo, ikakhulukazi uma uqala ukwelashwa noma ngemva kokunyuswa komthamo:

• Ukuzizwa unovalo, ukhathazekile, noma ungakhululeki
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuhluleka ukulala noma ukuzizwa unamandla ngokweqile
• Ukujuluka okwengeziwe noma ukuzizwa ufudumele kakhulu
• Ukuncipha kwesisindo okungahlosiwe noma ukwanda kwesifiso sokudla
• Ukuba nobuhlungu bekhanda noma ukuzizwa uthuthumela
• Ukuphuma isifo sohudo noma ukuvama kokuhamba kwamathumbu

Lezi zimpawu zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi noma lapho udokotela wakho elungisa umthamo wakho. Abantu abaningi bathola ukulinganisela okulungile phakathi namasonto ambalwa kuya ezinyangeni zokuqala ukwelashwa.

Nakuba kungavamile, abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezempilo ngokushesha:

• Ubuhlungu besifuba noma ukushaya kwenhliziyo okukhulu
• Ukuphefumula kanzima kakhulu
• Izimpawu zokungezwani komzimba nezinto ezithile njengokuqubuka, ukuvuvukala, noma ubunzima bokuphefumula
• Ushintsho olukhulu lwemizwa noma ukudideka
• Ukukhathala okukhulu okungafani nezimpawu zakho ezivamile ze-thyroid

Ngokuvamile, abantu bangase bathuthukise isimo esibizwa ngokuthi isiphepho se-thyroid, esihilela amazinga e-hormone ye-thyroid aphezulu ngendlela eyingozi. Lokhu kungenzeka uma ngengozi uthatha umuthi omningi kakhulu noma unezinye izimo zempilo ezinzima.

Xhumana nodokotela wakho uma uhlangabezana nemiphumela emibi eqhubekayo noma ekhathazayo. Bangasiza ekunqumeni ukuthi ngabe udinga ukulungiswa komthamo noma ngabe enye inkinga ingase ibangele izimpawu zakho.

Ubani Ongafanele Athathe I-Liothyronine?

I-Liothyronine ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zenhliziyo zenza lo muthi ube yingozi ikakhulukazi ngoba i-T3 ingakhuphula izinga lokushaya kwenhliziyo nomsebenzi.

Akufanele uthathe i-liothyronine uma unesifo se-adrenal esingelashwa, isimo lapho amagland adrenal akho engakhiqizi i-cortisol eyanele. Ukuthatha i-hormone yegilo kulesi simo kungabangela i-adrenal crisis eyingozi.

Abantu abanesifo senhliziyo esanda kwenzeka, i-angina engazinzile, noma umfutho wegazi ophezulu ongagadiwe ngokuvamile akufanele baqale i-liothyronine kuze kube yilapho lezi zimo zizinzile. Umuthi ungenza umthwalo owengeziwe ohlelweni lwe-cardiovascular oluvele lonakele.

Nawa amanye amanye amakhondishini angase enze i-liothyronine ingafaneleki noma idinge ukuqashwa okukhethekile:

• Isifo semithambo yenhliziyo esibi kakhulu noma iziyaluyalu zesigqi senhliziyo
• Isifo sikashukela esingagadiwe (i-hormone yegilo ingathinta ushukela wegazi)
• I-Osteoporosis noma izinkinga zokulahlekelwa amathambo
• Umlando we-thyroid storm noma i-hyperthyroidism ebucayi
• Ezinye izimo zengqondo ezingase zibe zimbi ngokukhuthaza

Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile, nakuba ukushintshwa kwe-hormone yegilo kuvame ukudingeka ngalezi zikhathi. Udokotela wakho uzoqapha ngokucophelela umthamo wakho futhi akuqaphe eduze uma ukhulelwa ngenkathi uthatha i-liothyronine.

Uma uneminyaka engaphezu kwengama-65 noma unezimo eziningi zempilo, udokotela wakho cishe uzoqala ngomthamo ophansi futhi awunyuse kancane kancane ukuze unciphise ingozi yemiphumela emibi.

Amagama Omkhiqizo we-Liothyronine

Igama elivamile lomkhiqizo we-liothyronine e-United States yi-Cytomel, ebelitholakala iminyaka eminingi. Lo mkhiqizo uza ngamandla amaningi wamaphilisi ukuze kuvunyelwe ukulinganisa okunembile.

I-Triostat elinye igama lomkhiqizo, nakuba lisetshenziswa ikakhulukazi ezindaweni zasemtholampilo njengendlela yokujova ye-liothyronine. Abantu abaningi abathatha i-liothyronine ekhaya bazosebenzisa uhlobo lwethebhulethi yomlomo.

Izinhlobo ezivamile ze-liothyronine nazo ziyatholakala futhi zisebenza ngempumelelo njengezinhlobo ezinamagama. Ikhemisi lakho lingashintsha ngokuzenzakalelayo i-liothyronine ejwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo.

Uma ushintsha phakathi kwabakhiqizi abahlukene noma usuka emkhiqizweni uye kowavamile, udokotela wakho angase afune ukuhlola amazinga akho e-thyroid emasontweni ambalwa ngemva kokushintsha ukuze aqinisekise ukuthi amazinga akho e-hormone ahlala ezinzile.

Ezinye izindlela ze-Liothyronine

I-Levothyroxine (T4) iyona enye indlela ejwayelekile ye-liothyronine futhi empeleni iyindlela yokwelapha yokuqala yabantu abaningi abane-hypothyroidism. Iguqulwa ibe yi-T3 emzimbeni wakho futhi ivame ukuhlinzeka ngamazinga e-hormone azinzile usuku lonke.

Abanye abantu benza kahle ngemithi ehlanganisiwe ehlanganisa kokubili i-levothyroxine ne-liothyronine. Le ndlela izama ukulingisa lokho okungakhiqizwa yindlala ye-thyroid enempilo ngokwemvelo.

Imithi ye-thyroid eyomile yemvelo (NDT) efana ne-Armour Thyroid iqukethe ama-hormone e-T4 ne-T3 atholakala ezigulini ze-thyroid zezilwane. Abanye abantu bakhetha lezi, nakuba ngokuvamile bengatuswa njengendlela yokwelapha yokuqala.

Kubantu abangakwazi ukubekezelela ama-hormone e-thyroid okwenziwa, udokotela wakho angase ahlole ezinye izinketho noma aphenye ukuthi ngabe ezinye izimo ziyawafaka yini amagalelo ezimpawini zakho. Ngezinye izikhathi ukubhekana nokuntuleka kwezakhi noma ezinye izinkinga zempilo kungathuthukisa ukusebenza kwe-thyroid.

Ingabe i-Liothyronine Ingcono Kune-Levothyroxine?

I-Liothyronine akudingeki ukuthi ingcono kune-levothyroxine kubantu abaningi abane-hypothyroidism. I-Levothyroxine ithathwa njengendlela yokwelapha yegolide ngoba inikeza ukushintshwa kwe-hormone ye-thyroid okuzinzile, okuhlala isikhathi eside okusebenza kahle cishe kubantu abangama-80%.

Nokho, i-liothyronine ingase ibe ngcono kuwe uma umzimba wakho unenkinga yokuguqula i-T4 ibe yi-T3, noma uma uqhubeka nokuzwa izimpawu naphezu kokuhlolwa kwegazi okuvamile ku-levothyroxine. Abanye abantu bazizwa benamandla kakhulu futhi becacile engqondweni ku-liothyronine.

Izinzuzo eziyinhloko ze-liothyronine zihlanganisa ukuqala okusheshayo kokusebenza kanye nokulethwa okuqondile kwe-hormone esebenzayo i-T3. Lokhu kungasiza kubantu abadinga ukukhululeka kwezimpawu ngokushesha noma abanezinkinga zokuguqula.

Ngakolunye uhlangothi, i-levothyroxine inikeza amazinga e-hormone azinzile usuku lonke futhi ngokuvamile kulula ukuyilinganisa ngokuqhubekayo. Futhi ineminyaka eminingi yocwaningo olusekela ukusetshenziswa kwayo njengokwelashwa okuyinhloko kwe-hypothyroidism.

Udokotela wakho uzocabangela izimpawu zakho ezithile, imiphumela yokuhlolwa kwegazi, nokuthi usabele kanjani kwezinye izindlela zokwelapha lapho enquma ukuthi yimuphi umuthi ongasebenza kangcono kuwe. Akukho okukhethwa “okungcono” okujwayelekile - kuya ngezidingo zakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Liothyronine

Ingabe i-Liothyronine iphephile kubantu abanezifo zenhliziyo?

I-Liothyronine idinga ukuqapha okwengeziwe uma unezifo zenhliziyo ngoba i-T3 ingakhuphula izinga lokushaya kwenhliziyo futhi yenze inhliziyo yakho isebenze kanzima. Udokotela wakho uzodinga ukuhlola isimo sakho senhliziyo esithile futhi angase akuqale ngomthamo ophansi kakhulu uma enquma ukuthi izinzuzo zidlula izingozi.

Abantu abanezimo zenhliziyo ezinzile, ezilawulwa kahle bangase bakwazi ukuthatha i-liothyronine ngokuphepha ngokuqapha okucophelelayo. Udokotela wakho angase asebenze nodokotela wenhliziyo ukuze aqinisekise ukuthi inhliziyo yakho ingakwazi ukumelana nomuthi.

Uma unezifo zenhliziyo ezinzima noma ezingazinzi, udokotela wakho angase ancome ukwelapha leso simo kuqala ngaphambi kokuqala ukufaka i-hormone yegilo. Bangase futhi bakhethe i-levothyroxine ngaphezu kwe-liothyronine ngoba ivame ukuba nemiphumela emnene enhliziyweni.

Ngingenzani uma ngiphuzile i-Liothyronine eningi ngengozi?

Uma ngengozi uphuza i-liothyronine eningi, ungesabi, kodwa xhumana nodokotela wakho noma usokhemisi ngokushesha ukuze uthole isiqondiso. Ukuphuza umthamo owengeziwe ngezikhathi ezithile akunakwenzeka ukuthi kubangele ingozi enkulu, kodwa kubalulekile ukuthola iseluleko esivela kochwepheshe.

Qaphela izimpawu ze-hormone yegilo eningi, njengokushaya kwenhliziyo okusheshayo, ukukhathazeka, ukujuluka, noma ukuzizwa unovalo. Uma uhlangabezana nezimpawu ezinzima njengobuhlungu besifuba, ubunzima bokuphefumula, noma ukucasuka okukhulu, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha.

Ungazami "ukulinganisa" umthamo owengeziwe ngokuqaqa umthamo wakho olandelayo ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze njalo. Lokhu kungabangela amazinga akho e-hormone ukuthi ashintshe kakhulu ngendlela ehlukile.

Udokotela wakho angase ancome ukuqapha izimpawu zakho futhi mhlawumbe ahlolisise amazinga akho e-gilo uma uthathe okuningi kakhulu kunokuba kunqunywe. Bazokusiza ukuthi unqume inkambo engcono kakhulu yesenzo esekelwe ekutheni uthathe umuthi ongakanani owengeziwe.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Liothyronine?

Uma uphuthelwa umthamo we-liothyronine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungabangela izimpawu ze-hormone yegilo eningi. Kungcono ukuphuthelwa umthamo owodwa kunokubeka engcupheni yokuthatha okuningi kakhulu.

Uma uvame ukukhohlwa imithamo, zama ukusetha ama-alamu ocingo noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule. Ukuthatha imithamo yansuku zonke okuqhubekayo kubalulekile ekugcineni amazinga e-hormone yegilo ezinzile.

Xhumana nodokotela wakho uma uphuthelwa imithamo njalo, njengoba kungase kudingeke ukuthi balungise uhlelo lwakho lokwelapha noma bakusize ukuthi uthole amasu okuthuthukisa ukunamathela emithini.

Ngingayeka Nini Ukuthatha I-Liothyronine?

Akufanele uyeke ukuthatha i-liothyronine ngokuzumayo noma ngaphandle kwesiqondiso sikadokotela wakho, ngisho noma uzizwa ungcono. Abantu abaningi abane-hypothyroidism badinga ukushintshwa kwe-hormone yegilo yokuphila konke ukuze bagcine imetabolism ejwayelekile namazinga wamandla.

Udktela wakho angase acabange ukuyeka i-liothyronine uma i-hypothyroidism yakho yabangelwa izinto zesikhashana njengemithi ethile, ukugula okukhulu, noma izinguquko ezihlobene nokukhulelwa. Nokho, lesi sinqumo sidinga ukuhlolwa nokuqapha okucophelelayo.

Abanye abantu bangase bakwazi ukunciphisa umthamo wabo noma bashintshele kwenye imithi yegilo, kodwa lokhu kufanele kwenziwe ngaphansi kokuqondisa kwezokwelapha ngokuhlolwa kwegazi okuvamile ukuqapha amazinga e-hormone.

Uma ukhathazekile ngokuthatha imithi isikhathi eside, xoxa ngokukhathazeka kwakho nodokotela wakho. Bangachaza ukuthi kungani ukuqhubeka nokwelashwa kubalulekile empilweni yakho futhi babhekane nanoma yikuphi ukukhathazeka okuthile ongase ube nakho.

Ngingayithatha i-Liothyronine Ngesikhathi Ngikhulelwe?

I-Liothyronine ingasetshenziswa ngesikhathi sokukhulelwa lapho ukufakwa kwe-hormone yegilo kudingekile, nakuba i-levothyroxine ivame ukunqunyelwa abesifazane abakhulelwe. I-hypothyroidism engalashwanga ngesikhathi sokukhulelwa ingalimaza wena nomntwana wakho osakhula.

Udktela wakho cishe uzofuna ukuqapha amazinga akho egilo kaningi ngesikhathi sokukhulelwa futhi kungase kudingeke ukuthi alungise umthamo wakho njengoba izidingo zakho ze-hormone zishintsha. Ukukhulelwa ngokuvamile kwandisa isidingo sokufakwa kwe-hormone yegilo.

Uma uhlela ukukhulelwa noma uthola ukuthi ukhulelwe ngenkathi uthatha i-liothyronine, xhumana nodokotela wakho ngokushesha. Bazofuna ukuhlola amazinga akho egilo futhi mhlawumbe balungise uhlelo lwakho lokwelapha.

Ungayeki ukuthatha i-liothyronine uma ukhulelwa, ngoba lokhu kungaba yingozi ekukhuleni komntwana wakho. Udokotela wakho uzosebenza nawe ukuze aqinisekise ukuthi uthola ukwelashwa okuphephile nokusebenzayo ngesikhathi sokukhulelwa kwakho.