Yini iMacimorelin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

IMacimorelin iyimithi kadokotela esiza odokotela ukuthi bathole ukuntuleka kwe-growth hormone kubantu abadala. Isebenza ngokukhuthaza umzimba wakho ukuthi ukhiphe i-growth hormone, okuthi odokotela bakwazi ukuyilinganisa ngezivivinyo zegazi ukuze babone ukuthi i-pituitary gland yakho isebenza kahle yini.

Le mithi iza njengesixazululo somlomo osiphuzayo, okwenza kube yindlela elula uma iqhathaniswa nezivivinyo zokuxilonga ezindala ezazidinga imijovo. Udokotela wakho uzosebenzisa i-macimorelin njengengxenye yokuhlolwa okuphelele ukuze aqonde ukuthi umzimba wakho ukhiqiza ngokwanele yini i-growth hormone ngokwemvelo.

Yini iMacimorelin Esetshenziselwa Yona?

IMacimorelin yenzelwe ngqo ukuxilonga ukuntuleka kwe-growth hormone kubantu abadala (AGHD). Uma odokotela besola ukuthi ungase ube nale ndlela, badinga indlela ethembekile yokuhlola ukuthi i-pituitary gland yakho ikhiqiza kahle kangakanani i-growth hormone.

Le mithi isebenza njethuluzi lokuxilonga kunokuba ibe yindlela yokwelapha. Cabanga ngayo njengokuhlolwa kokucindezeleka kwe-pituitary gland yakho - iphonsela inselelo umzimba wakho ukuthi ukhiqize i-growth hormone ukuze odokotela bakwazi ukulinganisa impendulo. Lokhu kubasiza ukuthi banqume ukuthi izimpawu zakho zihlobene yini nokuntuleka kwe-growth hormone noma enye indlela.

Ukuntuleka kwe-growth hormone kubantu abadala kungabangela ukukhathala, ubuthakathaka bemisipha, ukwanda kwamafutha omzimba, kanye nokuncipha kwekhwalithi yempilo. Ukuba nokuxilongwa okunembile kuyisinyathelo sokuqala sokuthola ukwelashwa okufanele uma unesimo.

Isebenza Kanjani iMacimorelin?

IMacimorelin isebenza ngokulingisa i-hormone yemvelo ebizwa ngokuthi i-ghrelin, ekhomba i-pituitary gland yakho ukuthi ikhiphe i-growth hormone. Ithathwa njenge-growth hormone secretagogue enamandla, okusho ukuthi isebenza kahle kakhulu ekubangeleni le mpendulo.

Uma uthatha i-macimorelin, ibopha kuma-receptors athile ku-pituitary gland yakho kanye ne-hypothalamus. Lesi senzo sokubopha sithumela isignali eqinile yokukhipha i-growth hormone egazini lakho. Umuthi ufika ekusebenzeni okuphezulu kungakapheli imizuzu engama-45 kuya ehora elilodwa ngemva kokuwuthatha.

Ithimba lakho lezempilo lizodonsa amasampula egazi ngezikhathi ezithile ngemva kokuthatha umuthi ukuze kulinganiswe ukuthi mangakanani ama-growth hormone umzimba wakho owakhiqizayo. Impendulo evamile ikhombisa ukuthi i-pituitary gland yakho isebenza kahle, kuyilapho impendulo empofu ingase isikisela ukuntuleka kwe-growth hormone.

Kufanele Ngiyithathe Kanjani I-Macimorelin?

Uzothatha i-macimorelin njengomthamo owodwa ehhovisi likadokotela wakho noma endaweni yezokwelapha, hhayi ekhaya. Umuthi uza njengesixazululo somlomo osiphuzayo, futhi yonke inqubo idinga ukugadwa kwezokwelapha.

Ngaphambi kokuthatha i-macimorelin, uzodinga ukuzila ukudla okungenani amahora angu-8 - lokhu kusho ukuthi akukho ukudla, kodwa ngokuvamile ungaphuza amanzi. Udokotela wakho uzokunikeza imiyalelo ethile mayelana nokuthi uyeke nini ukudla nokuphuza ngaphambi kokuhlolwa kwakho. Lesi sikhathi sokuzila ukudla sibalulekile ngoba ukudla kungaphazamisa imiphumela yokuhlolwa.

Umuthi ngokwawo unambitheka kamnandi, futhi uzoqeda wonke umthamo ngesikhathi esisodwa. Ngemva kokuwuthatha, uzohlala endaweni yezokwelapha amahora amaningana ngenkathi abahlinzeki bezempilo bedonsa amasampula egazi ngezikhathi ezithile ukuze balinganise amazinga akho e-growth hormone.

Ngesikhathi sokuhlolwa, uzodinga ukuhlala ukhululekile futhi ugweme ukuzivocavoca umzimba, njengoba ukuzivocavoca nakho kungathinta amazinga e-growth hormone. Ithimba lakho lezempilo lizokuqapha kuyo yonke inqubo ukuze liqinisekise ukuthi ukhululekile futhi uphephile.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Macimorelin?

I-Macimorelin iyisivivinyo sokuxilonga esisodwa, hhayi ukwelashwa okuqhubekayo. Uzoyithatha kanye kuphela ngesikhathi sokuvakasha kwakho endaweni yezokwelapha ukuze kuhlolwe ukuntuleka kwe-growth hormone.

Inqubo yonke yokuhlola ngokuvamile ithatha amahora angaba ngu-3-4 kusukela ngesikhathi uthatha imithi kuze kube yilapho zonke izibonelo zegazi ziqoqwa. Iningi lalesi sikhathi lihilela ukulinda phakathi kokudonswa kwegazi kunokwelashwa okusebenzayo.

Uma udokotela wakho edinga ukuphinda ukuhlolwa nganoma yisiphi isizathu, bazohlela ukuqokwa okuhlukile. Kodwa-ke, abantu abaningi badinga kuphela ukuthi leli hlola lenziwe kanye ukuze bathole isithombe esicacile sesimo sabo se-hormone yokukhula.

Yiziphi Imiphumela Eceleni ye-Macimorelin?

Abantu abaningi bayakwazi ukumelana ne-macimorelin kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Ezivamile kakhulu ngokuvamile zithambile futhi zesikhashana, zenzeka ngesikhathi noma ngemuva nje kokuhlolwa.

Nansi imiphumela emibi ongase uyithole ngesikhathi noma ngemuva kokuthatha i-macimorelin:

• Ukucasuka noma ukuzwa ukugula
• Isiyezi noma ukukhathala
• Ikhanda
• Ukukhathala noma ukukhathala
• Ukuzwa indlala eyengeziwe
• Ushintsho ekunambithekeni
• Ukuphatheka kabi kwesisu okuncane

Le miphumela emibi ejwayelekile ngokuvamile iyazixazulula yodwa kungakapheli amahora ambalwa. Ithimba lezokwelapha eliqapha ukuhlolwa kwakho lizobheka lezi zimo futhi lingakusiza ukuthi uzizwe ukhululekile uma zenzeka.

Ngenkathi kungavamile, abanye abantu bangase bathole imiphumela emibi ebaluleke kakhulu edinga ukunakekelwa kwezokwelapha ngokushesha. Lezi zimo ezinzima azivamile kodwa kubalulekile ukuziqaphela:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuphefumula kanzima
• Ukucasuka okukhulu noma ukuhlanza
• Ukungezwani komzimba nezinto ezithile njengokuqubuka, ukuluma, noma ukuvuvukala

Njengoba uzobe usesikhungweni sezokwelapha ngesikhathi sokuhlolwa, abahlinzeki bezempilo bangakwazi ukubhekana ngokushesha nanoma yiziphi izimpawu ezikhathazayo ezingase zivele. Lokhu kulungiselelwa okuqondiswayo kuqinisekisa ukuphepha kwakho kuyo yonke inqubo yokuxilonga.

Ubani Ongafanele Athole i-Macimorelin?

Abantu abathile kufanele bagweme i-macimorelin ngenxa yokukhathazeka ngokuphepha noma ingozi yemiphumela yokuhlolwa engalungile. Udokotela wakho uzobukeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokuncoma lolu vivinyo.

Akufanele uthathe i-macimorelin uma unesinye salezi zimo:

• Ukungezwani okwaziwayo ne-macimorelin noma izithako zayo
• Izinkinga zesibindi ezinzima noma isifo sesibindi esisebenzayo
• Isifo sezinso esinzima
• Ukuquleka kwenhliziyo kwamuva noma izimo zenhliziyo ezingazinzile
• Umfutho wegazi ophezulu ongagadiwe
• Amathumba e-pituitary asebenzayo

Ukukhulelwa nokuncelisa nazo zidinga ukucatshangelwa okukhethekile, njengoba ukuphepha kwe-macimorelin kungakahlolwa kulezi zimo. Udokotela wakho uzoxoxa ngezinketho zokuhlolwa ezingezinye uma ukhulelwe noma uncelisa.

Imithi ethile ingaphazamisa ukusebenza kahle noma ukuphepha kwe-macimorelin. Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa:

• Izithasiselo ze-hormone yokukhula
• Ama-corticosteroids
• Imithi ethinta isigqi senhliziyo
• Imithi yomfutho wegazi
• Imithi yesifo sikashukela

Umhlinzeki wakho wezempilo uzosiza ekunqumeni ukuthi i-macimorelin iphephile futhi ifanele isimo sakho esithile. Bangase bancomise izindlela zokuhlola ezingezinye uma unezinye izinto ezingavumelekile.

Amagama Omkhiqizo we-Macimorelin

I-Macimorelin itholakala ngaphansi kwegama lomkhiqizo elithi Macrilen e-United States. Lolu okwamanje yilona kuphela uhlobo olutholakala ngokuthengisa lolu hlobo lomuthi.

I-Macrilen ikhiqizwa yi-Aeterna Zentaris futhi yathuthukiswa ngqo ukuxilonga ukuntuleka kwe-hormone yokukhula kubantu abadala. Udokotela wakho uzobhekisela kuyo nganoma yiliphi igama - i-macimorelin noma i-Macrilen - futhi asho umuthi ofanayo.

Njengoba leli kuyilapho elikhethekile lokuxilonga, litholakala kuphela ezikhungweni zezempilo ezenza ukuhlolwa kwe-growth hormone. Ngeke ulithole emakhemisi avamile ngoba lidinga ukugadwa kwezokwelapha ngesikhathi sokuphathwa.

Ezinye izindlela zeMacimorelin

Ezinye izivivinyo eziningana zingaxilonga ukuntuleka kwe-growth hormone, nakuba ngayinye inezinzuzo zayo kanye nemikhawulo yayo. Udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe esimweni sakho esithile kanye nomlando wakho wezokwelapha.

Uvivinyo lokubekezelela i-insulin (ITT) lubhekwa njengezinga legolide lokuxilonga ukuntuleka kwe-growth hormone. Nokho, ludinga ukuqapha ngokucophelela ngoba luhilela ukwehlisa ngamabomu ushukela wakho wegazi, okungaba ngaphandle kokunethezeka futhi kube yingozi kubantu abathile.

Uvivinyo lokukhuthaza i-arginine olunye olunye oluvamile oluphephe kuno-ITT. I-Arginine iyi-amino acid ekhuthaza ukukhululwa kwe-growth hormone, kodwa ayinamandla njenge-macimorelin futhi ingase ingasebenzi kahle kuzo zonke iziguli.

Uvivinyo lokukhuthaza i-glucagon lunikeza enye inketho, ikakhulukazi kubantu abangakwazi ukuhlolwa kokubekezelela i-insulin ngokuphepha. I-Glucagon iyi-hormone ekhuthaza ngokungaqondile ukukhululwa kwe-growth hormone, nakuba ingase ibangele isicanucanu kaningi kune-macimorelin.

Udokotela wakho uzocabangela izinto ezifana neminyaka yakho, impilo yonke, ezinye izimo zezokwelapha, kanye nemiphumela yokuhlolwa kwangaphambilini lapho ekhetha indlela efanele yokuxilonga kuwe.

Ingabe i-Macimorelin ingcono kunezinye izivivinyo ze-Growth Hormone?

I-Macimorelin inikeza izinzuzo eziningana ngaphezu kwezivivinyo zendabuko ze-growth hormone, okuyenza ibe yinketho ekhethwayo ezimweni eziningi. Ngokuvamile iphephe futhi inethezekile kunezinye izindlela ngenkathi inikeza imiphumela ethembekile.

Uma kuqhathaniswa nokuhlolwa kokubekezelelana kwe-insulin, i-macimorelin iphephe kakhulu ngoba ayibeki engozini yokubangela ushukela wegazi ophansi ngendlela eyingozi. Ukuhlolwa kwe-insulin kungaba yingozi ikakhulukazi kubantu abanezifo zenhliziyo, izifo zokuthimula, noma isifo sikashukela, kanti i-macimorelin iphephile kubantu abaningi.

I-Macimorelin iphinde ilungele kakhulu kunezivivinyo ezisekelwe emijovweni. Umane nje uphuze umuthi kunokuba uthole imijovo, okutholakala abantu abaningi bekhululekile ngakho. Indlela yomlomo iphinde iqede ukukhathazeka mayelana nokusabela endaweni yokujova noma ukukhathazeka okuhlobene nenaliti.

Uvivinyo lunikeza imiphumela ethembeke njengezindlela zendabuko. Ucwaningo lubonisa ukuthi i-macimorelin ikhomba ngokunembile ukuntuleka kwe-hormone yokukhula ngokuzwela okuphezulu kanye nokucacisa, okusho ukuthi ikhomba ngendlela efanele bobabili abantu abanesimo kanye nalabo abangenaso.

Nokho, i-macimorelin ayilungi ngokuzenzakalelayo kuwo wonke umuntu. Abanye abantu bangase badinge izivivinyo ezingezinye ezisekelwe ezimweni zabo zezokwelapha ezithile noma uma imiphumela yokuqala ingacacile. Udokotela wakho uzosiza ukunquma ukuthi yiluphi uhlobo lokuhlolwa olufanele kakhulu isimo sakho somuntu ngamunye.

Imibuzo Evame Ukubuzwa Mayelana ne-Macimorelin

Ingabe i-Macimorelin iphephile kubantu abanesifo sikashukela?

I-Macimorelin ngokuvamile ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Ngokungafani nokuhlolwa kokubekezelelana kwe-insulin, i-macimorelin ayibangeli ukwehla okuyingozi kwamazinga kashukela egazini.

Nokho, usazodinga ukuzila ukudla ngaphambi kokuhlolwa, okungase kuthinte ukulawulwa kukashukela wakho egazini. Udokotela wakho uzosebenza nawe ukuze alungise imithi yakho yesifo sikashukela ngokuphepha ngesikhathi sokuhlolwa. Bangase batusa ukuhlola ushukela wakho wegazi kaningi ngaphambi nangemva kokuhlolwa.

Isidingo sokuzila ukudla ngokuvamile singamahora angu-8, okulawulekayo kubantu abaningi abanesifo sikashukela. Ithimba lakho lezempilo lizokuqapha eduze ngesikhathi sokuhlolwa ukuze liqinisekise ukuthi ushukela wakho wegazi uhlala ngaphakathi kwamabanga aphephile.

Kumele Ngenzeni Uma Ngizizwa Ngigula Ngesikhathi Sokuhlolwa Kwe-Macimorelin?

Uma uzizwa unesiyezi, unesiyezi, noma ungazizwa kahle ngesikhathi sokuhlolwa, tshela ithimba lakho lezempilo ngokushesha. Baqeqeshwe ukubhekana nalezi zimo futhi bangakusiza uzizwe ukhululekile.

Ngesicanucanu esincane, bangase banikeze imithi elwa nesicanucanu noma baphakamise izinguquko zesikhundla ezingasiza. Uma uzizwa unesiyezi, cishe bazokucela ukuthi ulale phansi futhi baqaphe umfutho wegazi lakho nesilinganiso senhliziyo.

Khumbula ukuthi usesikhungweni sezokwelapha ngesikhathi sokuhlolwa, ngakho usizo lochwepheshe luhlala lutholakala. Unganqikazi ukukhuluma nganoma yikuphi ukungakhululeki - ithimba lakho lezempilo lifuna ukuqinisekisa ukuthi uphephile futhi ukhululekile ngangokunokwenzeka.

Ngingakwazi Ukushayela Ngemuva Kokuthatha I-Macimorelin?

Kufanele uhlele ukuthi omunye umuntu akuqhubele ekhaya ngemuva kokuhlolwa kwe-macimorelin. Umuthi ungadala isiyezi, futhi ubusufuna ukuzila ukudla, okungathinta ukuqapha kwakho nesikhathi sokusabela.

Izikhungo eziningi zezokwelapha zincoma ukuthi ube nomngani noma ilungu lomndeni elizokulanda, noma usebenzise isevisi yokugibela esikhundleni sokuzishayela. Lokhu kuyisinyathelo sokuphepha sokuvikela wena nabanye abashayeli emgwaqeni.

Ngokuvamile uzobuyela kokujwayelekile kungakapheli amahora ambalwa ngemuva kokuhlolwa, kodwa kungcono ukuqapha. Hlela ukuthatha kalula usuku lonke futhi uqale kabusha imisebenzi ejwayelekile ngosuku olulandelayo.

Ngizokwazi Nini Imiphumela Yami Yokuhlolwa?

Udkt wakho ngokuvamile uzoba nemiphumela yokuqala kungakapheli izinsuku ezimbalwa kuya evikini ngemuva kokuhlolwa kwakho. Amasampula egazi adinga ukuhlaziywa elabhorethri, futhi imiphumela idinga ukuhunyushwa ngokucophelela.

Umhlinzeki wakho wezempilo uzohlela i-aphoyintimenti yokulandela ukuze axoxe ngemiphumela nokuthi isho ukuthini empilweni yakho. Bazochaza ukuthi ngabe amazinga akho e-hormone yokukhula ajwayelekile noma ngabe ukuhlolwa okwengeziwe noma ukwelashwa kungadingeka.

Uma imiphumela iphakamisa ukuntuleka kwe-growth hormone, udokotela wakho uzoxoxa ngezinketho zokwelapha kanye nezinyathelo ezilandelayo. Uma imiphumela ijwayelekile, bazokusiza ukuthi uhlole ezinye izimbangela ezingase zibe khona zezimpawu zakho.

Iqonde kangakanani i-Macimorelin Test?

I-macimorelin test iqonde kakhulu ekutholeni ukuntuleka kwe-growth hormone kubantu abadala. Izifundo zomtholampilo zikhombisa ukuthi ikuhlonza ngendlela efanele lesi simo cishe kuma-92-96% wamacala.

Lolu vivinyo lunokuzwela okuphezulu (lubamba abantu abaningi abanokuntuleka kwe-growth hormone) kanye nokucacisa okuphezulu (alibona ngendlela engafanele abantu abangenaso lesi simo). Lokhu kwenza kube yithuluzi elinokwethenjelwa lokuxilonga.

Nokho, njenganoma yiluphi olunye uhlobo lokuhlolwa kwezokwelapha, aluphelele ngo-100%. Udokotela wakho angase ancome ukuhlolwa okwengeziwe noma ukuhlolwa uma izimpawu zakho zingahambisani nemiphumela yokuhlolwa kwakho, noma uma bedinga ulwazi olwengeziwe ukuze benze ukuxilongwa okuphelele.