Mavacamten (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Camzyos
Mayelana naleli khambi
I-Mavacamten isetyenziselwa ukwelapha i-hypertrophic cardiomyopathy (HCM) ephazamisayo enezimpawu. Lolu dokotela lusiza ekuthuthukiseni izimpawu zakho nekhono lokuba usebenzayo. Lolu dokotela lutholakala kuphela ngaphansi kohlelo lokusabalalisa oluqediwe oluthi Camzyos™ REMS (Uhlelo Lokuhlola Ubungozi Nokunciphisa). Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, kufanele kuqhathaniswe ingozi yokusebenzisa imithi nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluhlukile noma ukusabela okungokwe-alerji kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokungezwani, njengokudla, iziboshwa, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-mavacamten kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-mavacamten kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akusikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyisebenzisa kangakanani enye noma zombili izidakamizwa. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akusikhuthazwa, kodwa kungase kungakugwemeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza ngokuqondile njengoba kunqunyiwe udokotela wakho. Ungathathi okuningi kwalokhu, ungaluthathi kaningi, futhi ungaluthathi isikhathi eside kunalokho udokotela wakho akuqondile. Ukwenza kanjalo kungandisa amathuba ezingozi ezihambisana naleli leyeza. Kubaluleke kakhulu ukuqonda izidingo ze-Ultomiris® REMS program, futhi uqonde iCamzyos™ Medication Guide. Funda futhi ulandele le miyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Cela umthengisi wezidakamizwa i-medication guide uma ungenayo. Ungathatha leli leyeza ngokudla noma ngaphandle kokudla. Gwinya ikhaphsuli yonke. Ungayiqhekeza, uyigaye, noma uyivule. Inani leli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani ajwayelekile aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondile ukuba wenze njalo. Inani leyeza olithathayo lixhomeke emandleni leli leyeza. Futhi, inani lezinye olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezinye, nobude besikhathi olithatha leli leyeza kuya ngenkinga yezokwelapha oyisebenzisela leli leyeza. Uma uphuthelwa yisilinganiso saleli leyeza, silithathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sesilinganiso sakho esilandelayo, susa isilinganiso esiphuthelwe bese ubuyela esikhathini sakho sokuthatha imithi. Ungawandisi amanani. Gcina imithi esitsheni esivalekile ekamelweni lokushisa, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungayivumeli ukuba iqhube. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasasetshenziswa. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.