Yini i-Mesna: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Mesna iyimithi evikelayo esiza ukuvimbela ukulimala kwesitho somchamo uma wamukela imithi ethile ye-chemotherapy. Isebenza njengendlela yokuvikela isitho sakho somchamo, iqeda amakhemikhali ayingozi okungenjalo angabangela ukucasuka okukhulu noma ukuphuma kwegazi.

Le mithi ivamise ukunikezwa kanye nokwelashwa kwe-chemotherapy equkethe i-ifosfamide noma i-cyclophosphamide. Ithimba lakho lokunakekelwa kwezempilo lizoxhumanisa isikhathi ngokucophelela ukuqinisekisa ukuthi uthola ukuvikelwa okungcono kakhulu.

Yini i-Mesna?

I-Mesna iyimithi eyenzelwe ngqo ukuvikela isitho sakho somchamo ngesikhathi sokwelashwa kwe-chemotherapy. Le mithi idala umgoqo ovikelayo ovimbela imikhiqizo eyingozi yokuhlukanisa ekulimaleni ukugqoka kwesitho sakho somchamo.

Cabanga nge-mesna njengomqaphi wakho siqu wesitho somchamo ngesikhathi sokwelashwa komdlavuza. Lapho imithi ethile ye-chemotherapy ihlukaniswa emzimbeni wakho, ingakha izinto eziyingozi ezicasula isitho sakho somchamo. I-Mesna ingena ukuze iqede lezi zinhlobo zobuthi ngaphambi kokuba zilimaze.

Le mithi ingeyeqembu elibizwa ngokuthi ama-cytoprotective agents. Lokhu kusho ukuthi ivikela amaseli anempilo ngenkathi ivumela i-chemotherapy yakho ukuthi iqhubeke isebenza ngokumelene namaseli omdlavuza.

Isetshenziselwani i-Mesna?

I-Mesna isetshenziswa ikakhulukazi ukuvimbela i-hemorrhagic cystitis, isimo esibucayi sesitho somchamo esingenzeka ngemithi ethile ye-chemotherapy. Lesi simo sibangela ukuvuvukala okukhulu kwesitho somchamo nokuphuma kwegazi okungaba buhlungu futhi kuyingozi.

Udokotela wakho uzokunikeza i-mesna uma wamukela i-ifosfamide noma i-high-dose cyclophosphamide chemotherapy. Le mithi enamandla yokulwa nomdlavuza ingakha ama-metabolites anobuthi alimaza izicubu zesitho sakho somchamo ngaphandle kokuvikelwa okufanele.

Le mithi ngezinye izikhathi isetshenziswa kwezinye izimo lapho ukuvikelwa kwesitho somchamo kudingeka. Udokotela wakho we-oncologist angase ayincomise ekwelashweni okuthile okungokwesipiliyoni noma uma unezici eziyingozi ezithile zezinkinga zesitho somchamo.

Isebenza Kanjani I-Mesna?

I-Mesna isebenza ngokubopha kumakhemikhali ayingozi abizwa ngokuthi i-acrolein kanye neminye imetabolites enobuthi eyakheka lapho imithi ye-chemotherapy ihlakazeka emzimbeni wakho. Le nqubo yokubopha iqeda lezi zinto eziyingozi ngaphambi kokuthi zifinyelele esinyeni sakho.

Lo muthi uthathwa njengomuthi ovikela ngamandla amancane. Yenzelwe ngqo ukusebenza ohlelweni lwakho lomchamo, lapho igxila khona ukuhlinzeka ngokuvikeleka okuphezulu lapho ukudinga kakhulu.

Uma i-mesna isibophezele ezintweni ezinobuthi, umzimba wakho uziqeda ngokuphepha lezi zinhlanganisela ezingathathi hlangothi ngomchamo wakho. Le nqubo yenzeka ngokuqhubekayo ngenkathi imithi ye-chemotherapy isemzimbeni wakho.

Kufanele Ngiyithathe Kanjani I-Mesna?

I-Mesna ngokuvamile inikezwa njengepilisi yomlomo noma uketshezi, nakuba inganikezwa futhi nge-intravenously ezindaweni zase-hospital. Ithimba lakho lezempilo lizinqumela indlela engcono kakhulu ngokusekelwe ohlelweni lwakho oluthile lokwelashwa.

Thatha i-mesna ngamanzi amaningi ukuze ikusize isebenze ngempumelelo futhi isekele ukusebenza kwezinso zakho. Akudingeki ukuthi uyithathe nokudla, kodwa ukudla ukudla okulula kungasiza ukunciphisa noma yikuphi ukuphazamiseka kwesisu.

Isikhathi sokuthatha imithamo yakho ye-mesna sibalulekile futhi sizoxhunyaniswa ngokucophelela neshejuli yakho ye-chemotherapy. Ngokuvamile uzoyithatha ngaphambi, ngesikhathi, nangemva kokufakwa kwe-chemotherapy yakho ngokulandela uhlu lwesikhathi oluthile oluhlinzekwa ithimba lakho lezokwelapha.

Ungalokothi ulungise isikhathi noma weqe imithamo ngokwakho. Ukuvikeleka i-mesna ekunikezayo kuncike esikhathini, futhi ukweqa imithamo kungashiya isinye sakho sibhekene nomonakalo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Mesna?

Uzothatha i-mesna kuphela ngesikhathi semijikelezo yakho ye-chemotherapy equkethe i-ifosfamide noma i-cyclophosphamide. Ubude besikhathi buxhomeke kunqubo yakho ethile yokwelashwa umdlavuza, engahluka ezinsukwini ezimbalwa kuya ezinyangeni eziningana.

Iziguli eziningi zithatha i-mesna ngesikhathi somjikelezo ngamunye we-chemotherapy, kanye nemithamo eyengeziwe ngemuva ukuqinisekisa ukuvikeleka okuphelele. Udokotela wakho we-oncologist uzokwenza isimiso esinemininingwane esihambisana ngokuphelele nohlelo lwakho lokwelashwa komdlavuza.

Umuthi awudingi inqubo yokunciphisa kancane kancane. Uma umjikelezo wakho we-chemotherapy usuqediwe futhi imithi isusiwe emzimbeni wakho, ungaqeda ukuthatha i-mesna njengoba uqondiswa ithimba lakho lezempilo.

Yiziphi Imiphumela Eceleni Ye-Mesna?

I-Mesna ngokuvamile ibangela imiphumela emincane eceleni kunezinye izidakamizwa eziningi ezisetshenziswa ngesikhathi sokwelashwa komdlavuza. Abantu abaningi bayayibekezelela kahle, ikakhulukazi uma iqhathaniswa nezinkinga ezinzima zomchamo ezizivimbayo.

Imiphumela ejwayelekile eceleni ongase uyithole ihlanganisa isicanucanu, ukuhlanza, noma ikhanda elincane. Lezi zimpawu zivame ukulawuleka futhi zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nawa imiphumela eceleni evame kakhulu ukubikwa iziguli:

• Ukuphazamiseka kwesisu noma isicanucanu
• Ikhanda elincane
• Ukuphuma kwendle noma izitulo ezixekile
• Ukukhathala noma ukuzizwa ukhathele
• Ukunambitheka okubi emlonyeni wakho
• Isiyezi

Le miphumela ejwayelekile ivame ukuba mnene futhi yesikhashana. Ithimba lakho lezempilo lingase linikeze izindlela zokuphatha lezi zimpawu uma ziba yinkinga.

Imiphumela eceleni engavamile kodwa ebucayi ingenzeka, nakuba ingavamile. Qaphela izimpawu zokungezwani komzimba nezinto ezithile, ubuhlungu obukhulu besisu, noma ukuphuma kwegazi okungavamile.

Nawa imiphumela eceleni engavamile kodwa ebalulekile okufanele uziqaphele:

• Ukungezwani komzimba okukhulu nezinto ezithile ezinamabala, ukuvuvukala, noma ubunzima bokuphefumula
• Isicanucanu esiqhubekayo esibi noma ukuhlanza
• Izimpawu zezinkinga zesibindi njengokushintsha kombala kwesikhumba noma amehlo abe phuzi
• Ukulimala noma ukuphuma kwegazi okungavamile
• Ubuhlungu obukhulu besisu
• Igazi emchamweni naphezu kokuthatha i-mesna

Xhumana nethimba lakho lezempilo ngokushesha uma uhlangabezana nanoma yiziphi zalezi zimpawu ezinzima. Bangakwazi ukuhlola ngokushesha isimo futhi balungise ukwelashwa kwakho uma kudingeka.

Obani okungafanele bathathe i-Mesna?

Bambalwa kakhulu abantu abangakwazi ukuthatha i-mesna, njengoba ngokuvamile iphephile kubantu abaningi abathola i-chemotherapy. Kodwa-ke, izimo ezithile zezokwelapha noma ukungezwani komzimba kungase kukwenze kungafaneleki kuwe.

Akufanele uthathe i-mesna uma uke waba nokusabela okukhulu komzimba kuyo esikhathini esidlule. Xhumana nodokotela wakho mayelana nanoma yikuphi ukusabela okwenzeke ngaphambilini emithini, ikakhulukazi lezo eziqukethe izinhlanganisela zesulfure.

Abantu abanezinkinga ezinzima zezinso bangase badinge imithamo elungisiwe noma ukuqapha okukhethekile. Ithimba lakho lezempilo lizohlola ukusebenza kwezinso zakho ngaphambi kokuqala i-mesna ukuze liqinisekise ukuthi iphephile kuwe.

Abesifazane abakhulelwe badinga ukucatshangelwa okukhethekile, nakuba i-mesna ingase isetshenziswe uma izinzuzo zidlula izingozi. Udokotela wakho we-oncologist uzohlola ngokucophelela ukuvikelwa i-mesna ekunikezayo ngokumelene nanoma yikuphi ukukhathazeka okungaba khona.

Amagama e-Mesna Brand

I-Mesna iyatholakala ngaphansi kwegama lomkhiqizo elithi Mesnex emazweni amaningi. Lena yifomula evame kakhulu ukunqunywa futhi iza ngesimo somlomo nesokujova.

Izinhlobo ezivamile ze-mesna nazo ziyatholakala futhi zisebenza ngempumelelo njengenguqulo yegama lomkhiqizo. Ikhemisi lakho ngokuvamile lizohlinzeka nganoma iyiphi inguqulo etholakala kalula noma eshibhile.

Isithako esisebenzayo sihlala sifana kungakhathaliseki igama lomkhiqizo. Ithimba lakho lezempilo lizoqinisekisa ukuthi uthola ifomula efanelekayo yezidingo zakho ezithile.

Ezinye izindlela ze-Mesna

Zimbalwa kakhulu ezinye izindlela ze-mesna zokuvikela isinye ngesikhathi se-chemotherapy. Ihlala iyindinganiso yegolide yokuvimbela i-hemorrhagic cystitis ngemithi ye-ifosfamide ne-cyclophosphamide.

Kwezinye izimo, odokotela bangase basebenzise ukuchelela isinye okuqhubekayo noma balungise imithamo ye-chemotherapy ukuze banciphise ubuthi besinye. Kodwa-ke, lezi zindlela ngokuvamile azisebenzi kangako kunokuvikelwa kwe-mesna.

Ukunywa kwamanzi amaningi nokuchama njalo kungahlinzeka ngokuvikeleka okwengeziwe, kodwa lezi zinyathelo zihambisana kunokuba zithathe indawo ye-mesna. Ithimba lakho lezokwelapha lizosebenzisa inhlanganisela ephumelela kakhulu yamasu okuvikela isimo sakho.

Ingabe i-Mesna Ingcono Kunezinye Izivikeli Zomchamo?

I-Mesna ithathwa njengomuthi ophumelela kakhulu ekuvikeleni ukulimala komchamo okubangelwa yi-chemotherapy. Akukho omunye umuthi oye wabonakala ethembekile noma esebenza kahle ngale njongo ethile.

Ucwaningo lubonisa ngokuqhubekayo ukuthi i-mesna inciphisa kakhulu ingozi ye-hemorrhagic cystitis uma iqhathaniswa nezinye izinyathelo zokuvikela. Lo muthi unamashumi eminyaka empumelelo eqinisekisiwe ezinqubweni zokwelapha umdlavuza emhlabeni jikelele.

Ngenkathi ezinye izinyathelo zokusekela njengokwanda kokuthatha amanzi kubalulekile, zisebenza kangcono uma zihlanganiswe ne-mesna kunokuba zisetshenziswe zodwa. Udokotela wakho we-oncologist uzoncoma isu elibanzi kakhulu lokuvikela ukwelashwa kwakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Mesna

Ingabe i-Mesna Iphephile Kubantu Abanezifo Zezinso?

I-Mesna ingasetshenziswa kubantu abanezifo zezinso, kodwa idinga ukuqapha ngokucophelela futhi mhlawumbe ilungiswe umthamo. Ithimba lakho lezempilo lizohlola ukusebenza kwezinso zakho njalo ukuze liqinisekise ukuthi umuthi uyasetshenzwa ngokuphepha.

Abantu abanezinkinga zezinso eziphakathi nendawo bavame ukuyibekezelela i-mesna kahle. Kodwa-ke, labo abanezifo ezinzima zezinso bangase badinge imithamo ephansi noma ukuqapha njalo ukuze bavimbele noma yiziphi izinkinga.

Ngingenzani Uma Ngithatha I-Mesna eningi Ngengozi?

Xhumana nomhlinzeki wakho wezempilo noma isikhungo sokulawula ubuthi ngokushesha uma uthatha i-mesna eningi kunaleyo ebekiwe. Ngenkathi ukweqisa okukhulu kungavamile, kubalulekile ukuthola iseluleko sezokwelapha ngokushesha.

Izimpawu zokuthatha i-mesna eningi zingabandakanya isicanucanu esibi, ukuhlanza, noma isifo sohudo. Ungazami ukuzelapha lezi zimpawu wena uqobo - vumela ochwepheshe bezokwelapha baqondise ukunakekelwa kwakho.

Ngingenzani Uma Ngiphuthelwa Umthamo we-Mesna?

Xhumana nethimba lakho lezempilo ngokushesha uma uphuthelwa umthamo we-mesna. Isikhathi saleli khambi sibalulekile ukuvikela isinye sakho ngesikhathi sokwelashwa ngamakhemikhali.

Ungalokothi uphinde umthamo noma uzame ukulungisa imithamo ephuthelwe wedwa. Ithimba lakho lezokwelapha lizokweluleka ngendlela engcono kakhulu yokwenza ngokusekelwe ekutheni uphuthelwe nini umthamo kanye nohlelo lwakho lwe-chemotherapy.

Ngingayeka nini Ukuthatha i-Mesna?

Ungayeka ukuthatha i-mesna lapho ithimba lakho lezempilo linquma ukuthi imithi ye-chemotherapy isusiwe ohlelweni lwakho futhi isinye sakho asisengozini. Lokhu kuvamile ukwenzeka ngemva kwamahora angu-12-24 ngemva komthamo wakho wokugcina we-chemotherapy.

Udokotela wakho we-oncologist uzokunikeza imiyalelo ethile mayelana nokuthi uzothatha nini umthamo wakho wokugcina we-mesna. Landela le miyalelo ngokucophelela ukuze uqinisekise ukuvikelwa okuphelele kuyo yonke imijikelezo yakho yokwelashwa.

Ngingakwazi yini Ukuphuza Utshwala Ngenkathi Ngithatha i-Mesna?

Kungcono ukugwema utshwala ngenkathi uthatha i-mesna futhi uthola ukwelashwa nge-chemotherapy. Utshwala bungaphazamisa ikhono lomzimba wakho lokucubungula imithi futhi lungakhuphula ingozi yemiphumela emibi.

Ngaphezu kwalokho, utshwala bunganciphisa amanzi emzimbeni, okusebenza ngokumelene nokwanda kokuthathwa kwamanzi okusekela imiphumela evikelayo ye-mesna. Gxila ekuhlaliseni amanzi kahle ngamanzi nezinye iziphuzo ezingezona utshwala ngesikhathi sokwelashwa kwakho.