Yini Ukujovwa kweMidazolam: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

Ukujovwa kweMidazolam kuyisidambisi esinamandla esingaphansi kohlu lwemithi ebizwa ngokuthi yi-benzodiazepines. Udokotela wakho usebenzisa lo muthi ukukusiza ukuthi uphumule futhi uzizwe ubuthuntu ngaphambi kwezinqubo zezokwelapha, ukuhlinzwa, noma uma udinga ukudambisa okukhulu. Cabanga ngakho njengethuluzi lezokwelapha elithulisa ngobumnene uhlelo lwakho lwezinzwa uma uludinga kakhulu ezimweni zezokwelapha ezicindezelayo.

Yini Ukujovwa kweMidazolam?

Ukujovwa kweMidazolam kuyisidambisi esisebenza ngokushesha esisebenza ngqo ngomjikelezo wegazi lakho. Kungumndeni ofanayo wemithi njenge-Valium noma i-Xanax, kodwa yakhelwe ngqo izilungiselelo zezokwelapha lapho kudingeka khona ukudambisa okusheshayo, okulawulwayo. Abahlinzeki bezempilo bayinika ngomugqa we-IV, ukujova emsipheni, noma ngezinye izikhathi ngamakhala akho ezimweni eziphuthumayo.

Lo muthi ubhekwa njengonamandla kakhulu uma uqhathaniswa nemithi yokukhathazeka yomlomo. Ngenkathi amaphilisi ongase uwathathe ekhaya esebenza kancane kancane ngemizuzu engama-30-60, ukujovwa kwe-midazolam kuvame ukuqala ukusebenza ngemizuzu engu-1-3 uma kunikezwa ngomthambo. Lesi senzo esisheshayo senza ukuthi sibe yigugu elikhulu ezinqubweni zezokwelapha lapho isikhathi sibalulekile.

Yini Ukujovwa kweMidazolam Okusetshenziselwa Yona?

Odokotela basebenzisa ukujovwa kwe-midazolam ikakhulukazi ukukusiza ukuthi uzizwe uzolile futhi ulele ngaphambi kwezinqubo zezokwelapha. Ivame ukusetshenziselwa ama-colonoscopies, ama-endoscopies, ukuhlinzwa kwamazinyo, kanye nezinqubo ezincane zokuhlinzwa lapho udinga ukuthi uphumule kodwa ungabi nakuqwashisa ngokuphelele. Ungase futhi uyithole emagumbini eziphuthumayo ukusiza ukulawula ukuquleka noma iziqephu zokukhathazeka okukhulu.

Emayunithi okunakekelwa okukhulu, i-midazolam isiza ukugcina iziguli zikhululekile uma zikwimishini yokuphefumula noma zilulama ezifweni ezinzima. Iphinde isetshenziswe njengengxenye yezinqubo ze-anesthesia zokuhlinzwa okukhulu, isebenza kanye neminye imithi ukuqinisekisa ukuthi ukhululekile ngokuphelele kuyo yonke inqubo.

Ngaphandle kokusetshenziswa okuvamile, kunezimo ezikhethekile lapho i-midazolam ibaluleka khona. Amaqembu ezokwelapha eziphuthumayo ayisebenzisela ukusiza abantu abahlangabezana nokuthukuthela okukhulu, ukuhlaselwa ukwethuka, noma izimpawu zokuhoxiswa kotshwala. Ezindaweni zezingane, kusiza izingane ukuthi zihlale zizolile ngesikhathi sokuhlinzwa okwesabekayo, okwenza ukuthi okuhlangenwe nakho kungabi buhlungu kakhulu kokubili enganeni nomndeni wayo.

Isebenza Kanjani I-Midazolam Injection?

I-Midazolam isebenza ngokuthuthukisa imiphumela yamakhemikhali emvelo ebuchosheni bakho ebizwa nge-GABA. I-GABA injengesistimu yamabhuleki emvelo yobuchopho bakho, esiza ukwehlisa umsebenzi wemizwa futhi idale imizwa yokuzola nokuphumula. Lapho i-midazolam ithuthukisa imiphumela ye-GABA, idala isimo sokuthula, sokulala esenza izinqubo zezokwelapha zikhululeke kakhulu kuwe.

Lo muthi uthathwa njengomqina kakhulu emhlabeni wama-sedatives. Ngenkathi ngeke ikwenze ungaqapheli ngokuphelele njenge-anesthesia ejwayelekile, idala lokho odokotela abakubiza ngokuthi "ukuqeda umqondo." Lokhu kusho ukuthi uzozizwa ukhululeke kakhulu futhi ukozela, kodwa usengakwazi ukuphendula izwi likadokotela wakho nemiyalelo uma kudingeka.

Ubuhle be-midazolam ukuthi futhi inezindawo ze-amnesic, okusho ukuthi cishe ngeke ukhumbule okuningi ngenqubo ngemva kwalokho. Lokhu akuyona ingozi - empeleni kuyasiza ngoba kukuvimbela ekwakheni izinkumbulo ezicindezelayo mayelana nezinqubo zezokwelapha, okwenza ukwelashwa okuzayo kube lula ukukuphatha ngokomzwelo.

Kufanele Ngiyithathe Kanjani I-Midazolam Injection?

Ngeke uzinikeze i-midazolam injection - lokhu kuhlala kunikezwa ochwepheshe bezempilo abaqeqeshiwe ezindaweni zezokwelapha. Kodwa-ke, kunezinto ezibalulekile okudingeka uzenze ukuze uzilungiselele ukuthola lo muthi ngokuphepha.

Ukulungiselela kwakho ngokuvamile kuqala ngobusuku obandulela inqubo yakho. Udokotela wakho cishe uzokucela ukuthi ugweme ukudla noma ukuphuza noma yini amahora angu-8-12 ngaphambi kokuba uqokwe. Lesi sikhathi sokuzila ukudla sibalulekile ngoba i-midazolam ingathinta ukusabela komzimba wakho, futhi ukuba nokudla esiswini sakho kungaholela ezinkingeni uma uhlanza ngenkathi udakiwe.

Ngosuku lwenqubo yakho, gqoka izingubo ezikhululekile, ezilula futhi ususe noma iyiphi ubucwebe, amalensi okuxhumana, noma amazinyo okwenziwa njengoba kuyalelwe. Qiniseka ukuthi unomuntu omdala onomthwalo wemfanelo ongakushayela ekhaya ngemva kwalokho, njengoba imiphumela ye-midazolam ingahlala amahora amaningana ngisho nangemva kokuzwa ukuthi uqaphile.

Yazisa ithimba lakho lezempilo ngayo yonke imithi oyithathayo, okuhlanganisa imithi etholakala ngaphandle kwemvume kadokotela kanye nezithasiselo. Eminye imithi ingasebenzisana ne-midazolam, futhi udokotela wakho angase adinge ukulungisa umthamo noma isikhathi seminye imithi yakho ngokufanele.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Midazolam Injection?

I-Midazolam injection ngokuvamile iyisidakamizwa esisodwa esinikezwa ngokuqondile ngenqubo yakho noma isimo sezokwelapha. Ngokungafani nemithi yansuku zonke ongase uyithathe ekhaya, lokhu akuyona into ozoyisebenzisa ngokuphindaphindiwe noma isikhathi eside. Umthamo ngamunye ubhalwa ngokucophelela ngokuya ngezidingo zakho ezithile, isisindo, iminyaka, kanye nohlobo lwenqubo onayo.

Imiphumela ivamise ukuqala ngemizuzu engu-1-3 uma inikezwa nge-intravenously, noma ngemizuzu engu-5-15 uma inikezwa njengesijovo semisipha. Imiphumela ephezulu yenzeka cishe ngemizuzu engu-15-30 ngemva kokuphathwa, futhi imiphumela yokudambisa ngokuvamile ihlala amahora angu-2-6, kuye ngomthamo nokusabela kwakho ngakunye.

Ezindaweni zokunakekelwa okukhulu, iziguli zingase zithole i-midazolam ngokuqhubekayo nge-IV drip izinsuku noma ngisho namasonto ngenkathi zithola ukwelulama ezifweni ezinzima. Kodwa-ke, odokotela bayayiqapha ngokucophelela lokhu futhi banciphise kancane umthamo njengoba iziguli zithuthuka, ngaso sonke isikhathi besebenzela ukuyeka imithi ngokushesha nje lapho kuphephile ukwenza kanjalo.

Ziziphi Izimo Ezingezinhle Zomjovo We-Midazolam?

Abantu abaningi bayawuthola kahle umjovo we-midazolam, kodwa njenganoma imuphi umuthi, ungabangela imiphumela emibi. Ezivamile kakhulu empeleni ziyizandiso zalokho umuthi oklanyelwe ukukwenza - ukukwenza uzizwe ukozela futhi ukhululekile.

Nazi izimo ezingezinhle ongase uzithole, ukhumbula ukuthi lezi zivame ukuba mnene futhi zesikhashana:

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• Ukozela okungahlala amahora amaningana ngemuva kwenqubo yakho
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• Ukudideka kwesikhashana noma ukuzizwa

  Umjovo we-Midazolam awulungele wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokunquma ukuthi ukufanele yini. Ukuphikiswa okubaluleke kakhulu ukuthi uma unezinkinga ezinkulu zokuphefumula noma i-sleep apnea, njengoba i-midazolam inganciphisa kakhulu ukuphefumula kwakho.

  Akufanele uthole i-midazolam uma unokungezwani komzimba kuma-benzodiazepines noma yiziphi izingxenye zomjovo. Abantu abanezifo ezinzima zesibindi badinga ukucatshangelwa okukhethekile ngoba imizimba yabo icubungula imithi kancane kakhulu, okungaholela emiphumeleni ende eyingozi.

  Nazi ezinye izimo lapho i-midazolam ingase ingakulungele khona:

  • I-acute narrow-angle glaucoma (uhlobo oluthile lwesifo samehlo)
  • Ukucindezeleka okukhulu kokuphefumula noma ubunzima bokuphefumula
  • Ukukhulelwa, ikakhulukazi ngesikhathi sokukhulelwa kokuqala
  • Ukuncelisa (umuthi ungangena obisini lwebele)
  • I-Myasthenia gravis (isimo sokukhathala kwemisipha)
  • Izinkinga zenhliziyo ezinzima noma umfutho wegazi ophansi kakhulu

  Ubudala nabo buyisici esibalulekile. Iziguli ezigugile kanye nezingane ezincane kakhulu zidinga ukucatshangelwa okukhethekile kwemithamo ngoba zizwela kakhulu emiphumeleni yomuthi. Udokotela wakho uzolungisa umthamo ngokucophelela ngokuya ngeminyaka yakho, isisindo, kanye nesimo sempilo esiphelele.

  Uma unomlando wokusebenzisa izidakamizwa, ikakhulukazi ngotshwala noma ama-benzodiazepines, qiniseka ukuthi udokotela wakho uyakwazi lokhu. Ngenkathi kungakukhiphi ngokuzenzakalelayo ekutholeni i-midazolam, kudinga ukuqapha okukhethekile futhi mhlawumbe namasu ahlukene okulinganisa.

  Amagama Omkhiqizo we-Midazolam

  Umjovo we-Midazolam uyatholakala ngaphansi kwamagama amaningi omkhiqizo, nakuba izibhedlela nemitholampilo eminingi isebenzisa inguqulo ejwayelekile. Igama lomkhiqizo elivamile e-United States yi-Versed, ongase ulubone emarekhodini akho ezokwelapha noma uzwe ithimba lakho lezempilo likhuluma.

Eminye izinhlobo zamagama afaka i-Dormicum (esetshenziswa kwezinye izimakethe zamazwe ngamazwe) kanye nezinhlobo ezahlukahlukene ze-generic ezihamba nje nge "midazolam injection." Umuthi ngokwawo uyafana kungakhathaliseki igama lomkhiqizo - okubalulekile yidosi kanye nokugxila udokotela wakho akukhethayo esimweni sakho esithile.

Isikhungo sakho sokunakekelwa kwezempilo ngokuvamile sizogcina noma iyiphi inguqulo abayithole ithembeke kakhulu futhi ishibhile. Zonke izinguqulo kumele zihlangabezane nezindinganiso eziqinile ze-FDA zokuphepha nokusebenza kahle, ngakho-ke ungezwa uqiniseka kungakhathaliseki ukuthi yiluphi uhlobo olutholayo.

Ezinye izindlela ze-Midazolam Injection

Ngenkathi i-midazolam ingenye yezinto ezidume kakhulu zokuthulisa iziguli ezinqubweni zezokwelapha, kunezindlela eziningana ezingase zicatshangelwe udokotela wakho ngokusekelwe ezidingweni zakho ezithile nomlando wezokwelapha. Indlela ngayinye enezinzuzo zayo ezihlukile kanye nezinto okufanele zicatshangelwe.

I-Propofol mhlawumbe iyona ndlela ejwayelekile, ikakhulukazi ezinqubweni ezidinga ukuthuliswa okujulile. Isebenza ngokushesha kune-midazolam futhi iyaphela ngokushesha, okwenza ilungele izinqubo zokwelapha ezingaphandle lapho udinga ukululama ngokushesha. Kodwa-ke, idinga ukuqapha okujulile futhi ngokuvamile isetshenziswa ngama-anesthesiologists.

Ukuze uthole ukuthuliswa okulula, udokotela wakho angase akhethe i-lorazepam (Ativan) noma i-diazepam (Valium). Le mithi isebenza ngendlela efana ne-midazolam kodwa inemiphumela ehlala isikhathi eside. Zivame ukusetshenziswa uma ukuthuliswa okuqhubekayo kudingeka noma ezigulini ezingase zizuze ekukhululekeni kokukhathazeka okuhlala isikhathi eside.

I-Ketamine enye indlela ethandwa kakhulu ezinqubweni ezithile. Ngokungafani ne-midazolam, i-ketamine inikeza kokubili ukuthuliswa kanye nokukhululeka kobuhlungu, okwenza kube usizo ezinqubweni ezibuhlungu. Kodwa-ke, ingabangela imiphumela emibi ehlukene, okuhlanganisa amaphupho acacile noma ukudideka okwesikhashana.

Kubantwana abancane, odokotela ngezinye izikhathi basebenzisa ezinye izindlela ezifana ne-chloral hydrate kubantwana abasebancane kakhulu, noma i-nitrous oxide (igesi yokuhleka) ezinqumweni zamazinyo. Lezi zinketho zingaba mnene kubantwana abangase besatshiswe yimijovo.

Ingabe umjovo we-Midazolam ungcono kune-Lorazepam?

Ukuqhathanisa umjovo we-midazolam ne-lorazepam (Ativan) akukhona ukuthi omunye ungcono kunomunye - kumayelana nokuthi imuphi umuthi ofaneleka kakhulu esimweni sakho esithile. Zombili ziyizidakamizwa ze-benzodiazepine ezisebenza ngendlela efanayo, kodwa zinezikhathi ezihlukene nobude obenza ngamunye abe ngcono ngezinjongo ezihlukene.

Inzuzo enkulu ye-Midazolam isivinini sayo nokulindeleka kwayo. Iqala ukusebenza ngemizuzu embalwa futhi inesikhathi esifushane sokusebenza, ngokuvamile amahora angu-2-6. Lokhu kuyenza ilungele izinqubo zokwelapha lapho udinga ukululama ngokushesha futhi uhambe ngosuku olufanayo. Ukuqala kwayo okusheshayo kunikeza odokotela ukulawula okunembile ngesikhathi sokuthulisa.

I-Lorazepam, ngakolunye uhlangothi, inesikhathi eside sokusebenza, esihlala amahora angu-6-12 noma ngaphezulu. Lokhu kuyenza ibe ngcono ezimweni lapho kudingeka khona ukuthulisa okuqhubekayo noma ukukhululeka kokukhathazeka, njengasezikhathini ezinde zokuhlala esibhedlela noma ezigulini ezinokuphazamiseka okukhulu kokukhathazeka. Itholakala futhi ngezindlela zokujova nezomlomo, inikeza odokotela ukuguquguquka okwengeziwe.

Ezinqumweni zezokwelapha, i-midazolam ivame ukukhethwa ngenxa yokuqala kwayo okusheshayo nobude obufushane. Ukuphathwa okuqhubekayo kokukhathazeka noma izimo ezidinga ukuthulisa isikhathi eside, i-lorazepam ingase ibe yindlela engcono. Udokotela wakho uzocabangela izinto ezinjengobude benqubo yakho, umlando wakho wezokwelapha, nokuthi udinga ukululama ngokushesha kangakanani lapho enza lesi sinqumo.

Imibuzo Evame Ukubuzwa Mayelana Nomjovo we-Midazolam

Q1. Ingabe umjovo we-Midazolam uphephezelwa iziguli zenhliziyo?

Umjovo we-Midazolam ungaphephile ezigulini zenhliziyo, kodwa udinga ukucatshangelwa okukhethekile nokuqapha. Umuthi ungabangela ukwehla kwesikhashana kwengcindezi yegazi nesilinganiso senhliziyo, okungase kukhathaze abantu abanezimo zenhliziyo ezithile. Udokotela wakho wenhliziyo kanye nethimba lezokwelapha elenza inqubo yakho bazosebenzisana ukuze banqume ukuthi i-midazolam ilungele yini wena.

Uma unesifo senhliziyo esizinzile, i-midazolam ivame ukusetshenziswa ngempumelelo ngokugadwa ngokucophelela. Kodwa-ke, uma unesifo senhliziyo esibi kakhulu, ingcindezi yegazi ephansi kakhulu, noma ukuhlaselwa yinhliziyo kwakamuva, udokotela wakho angase akhethe ezinye izindlela zokuthulisa noma alungise umthamo ngokuphawulekayo. Okubalulekile ukuxhumana ngeqiniso ngesimo senhliziyo yakho nemithi yamanje.

Q2. Kufanele Ngenzeni Uma Ngisebenzisa I-Midazolam Eningi Ngengozi?

Ngeke uziphathele wena umjovo we-midazolam - uhlala unikezwa ochwepheshe bezempilo abaqeqeshiwe ababala ngokucophelela futhi baqaphe umthamo. Kodwa-ke, uma uke usola ukuthi uthole okuningi noma uhlangabezana nemiphumela emibi kakhulu, lokhu kuyisimo esiphuthumayo sezokwelapha esidinga ukunakwa ngokushesha.

Izimpawu zokweqisa kwe-midazolam zihlanganisa ukozela okukhulu lapho ungenakuvuswa, ubunzima bokuphefumula, izindebe noma izinzipho eziluhlaza okwesibhakabhaka, noma isilinganiso senhliziyo esinensayo kakhulu. Abahlinzeki bezempilo banomuthi wokulwa obizwa ngokuthi i-flumazenil engashintsha ngokushesha imiphumela ye-midazolam uma kudingeka. Yingakho izinqubo zezokwelapha ezisebenzisa i-midazolam zihlala zenzeka ezindaweni ezinemishini ephuthumayo nabasebenzi abaqeqeshiwe.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Midazolam?

Lo mbuzo awusebenzi kumjovo we-midazolam ngoba akuyona imithi oyithatha ngeshejuli ejwayelekile. Umthamo ngamunye unikezwa ngokuqondile ngenqubo yezokwelapha noma isimo esibukhali. Uma uhlelelwe inqubo edinga i-midazolam futhi udinga ukuhlela kabusha, vele uthinte umhlinzeki wakho wezempilo ukuze uhlele ukuqokwa okusha.

Uma usegunjini lokunakekelwa okukhulu lapho uthola khona ukumnika okuqhubekayo kwe-midazolam, ithimba lakho lezokwelapha lilawula zonke izinqumo zokulinganisa. Baqhubeka nokubheka isimo sakho futhi balungise imithi njengoba kudingeka - akukho "mthamo olahlekile" okufanele ukhathazeke ngawo.

Q4. Ngingayeka nini ukuthatha i-Midazolam Injection?

I-Midazolam injection ngokuvamile iyeka yodwa njengoba umzimba wakho ucubungula imithi ngemuva kwenqubo yakho. Ezimweni zomthamo owodwa njengezinqubo zokwelapha ezingaphandle, imithi iyaphela ngokwemvelo ngaphezu kwamahora angu-2-6 ngaphandle kwesidingo sesenzo esivela kuwe. Umsebenzi wakho ukuthi uphumule futhi uvumele umzimba wakho ukuthi ululame.

Ezigunjini zokunakekelwa okukhulu lapho iziguli zithola khona ukumnika okuqhubekayo kwe-midazolam, odokotela banciphisa kancane kancane umthamo njengoba iziguli zithuthuka. Le nqubo, ebizwa ngokuthi ukuyeka, ivimbela izimpawu zokuhoxiswa futhi iqinisekisa ukuthi iziguli zihlala zikhululekile njengoba zilulama. Ithimba lezokwelapha liphatha zonke izinqumo mayelana nokuthi imithi iyekwa nini futhi kanjani ngokusekelwe entuthukweni yakho nesimo sakho.

Q5. Ngingashayela ngemuva kokuthola i-Midazolam Injection?

Cha, awukwazi neze ukushayela ngemuva kokuthola i-midazolam injection. Lona ngomunye wemithetho ebaluleke kakhulu yokuphepha ehambisana nale mithi. Noma ngabe uzizwa uqaphile futhi ucabanga ukuthi usululame, imithi ingase isathinte isikhathi sakho sokuphendula, ukwahlulela, nokuxhumana kuze kube amahora angu-24 ngemuva kwenqubo yakho.

Kufanele ulungiselele umuntu omdala onomthwalo wemfanelo ukuthi akuqhubele ekhaya futhi ahlale nawe amahora amaningana ngemuva kwenqubo yakho. Lokhu akuyona nje isiphakamiso - kuyimfuneko yokuphepha ephoqwa yizo zonke izikhungo zezokwelapha. Hlela kusengaphambili ngokucela ilungu lomndeni noma umngane ukuthi akusize, noma cabangela ukusebenzisa isevisi yokugibela uma unomuntu ozokuphelezela futhi akusize ukuthi ufike ekhaya ngokuphepha.