Yini i-Naltrexone (Indlela yokujova ngaphakathi kwemisipha): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

Umjovo we-naltrexone intramuscular uyisibhamu sanyanga zonke esisiza abantu ukuthi bahlale beyeka utshwala noma ama-opioids. Lo muthi usebenza ngokuvimba imiphumela eklomelisayo yalezi zinto ebuchosheni bakho, okwenza kube lula ukugcina ukululama kwakho.

Cabanga ngakho njengesihlangu esivikelayo esihlala cishe inyanga. Uma uthola lo mjovo, uthatha isinyathelo esibalulekile ekululameni kwesikhathi eside ngokusekelwa ochwepheshe bezokwelapha abaqondayo uhambo lwakho.

Yini i-Naltrexone Intramuscular Injection?

I-Naltrexone intramuscular injection iyindlela esebenza isikhathi eside ye-naltrexone enikezwa njengesibhamu emsipheni wakho kanye ngenyanga. Ngokungafani namaphilisi ansuku zonke, lo mjovo unikeza amazinga emithi aqhubekayo emzimbeni wakho cishe izinsuku ezingama-30.

Umuthi unikezwa ngumhlinzeki wezempilo endaweni yezokwelapha. Lokhu kuqinisekisa ukuthi uthola umthamo ofanele kanye nokuqondiswa okufanele kwezokwelapha kuyo yonke imithi yakho.

Indawo yokujova ngokuvamile imisipha yakho yezinqe, lapho umuthi ukhululwa kancane kancane ngokuhamba kwesikhathi. Lokhu kukhishwa okuqhubekayo kusiza ukugcina ukuvikelwa okuqhubekayo ngokuphikisana nemiphumela yotshwala ne-opioid.

Isetshenziselwani i-Naltrexone?

I-Naltrexone intramuscular injection ikakhulukazi iphatha ukuphazamiseka kokusetshenziswa kotshwala kanye nokuphazamiseka kokusetshenziswa kwe-opioid kubantu abadala. Yenzelwe ngokuqondile abantu asebevele beyeka utshwala futhi abafuna ukugcina ukululama kwabo.

Ukuze uthole ukuphazamiseka kokusetshenziswa kotshwala, lo muthi usiza ukunciphisa ukulangazelela futhi kwenza ukuphuza kungabi nemivuzo eminingi. Abantu abaningi bakuthola kulula ukunamathela emigomweni yabo yokuyeka utshwala uma benalo lolu hlobo lokusekelwa kwanyanga zonke.

Lapho welapha ukuphazamiseka kokusetshenziswa kwe-opioid, i-naltrexone ivimba imiphumela ye-euphoric ye-opioids efana ne-heroin, izidakamizwa zokwelapha, kanye ne-fentanyl. Kodwa-ke, kufanele ukhululeke ngokuphelele kuma-opioids okungenani izinsuku eziyi-7-10 ngaphambi kokuqala ukwelashwa.

Udktela wakho angase futhi acabangele lo muthi uma uke waba nenkinga yokukhumbula ukuthatha amaphilisi e-naltrexone nsuku zonke. Umjovo wanyanga zonke ususa ukwenza izinqumo zansuku zonke mayelana nokuthobela imithi.

Isebenza Kanjani I-Naltrexone?

I-Naltrexone isebenza ngokuvimba ama-receptor e-opioid ebuchosheni bakho, okuyizona ezifanayo ama-receptor utshwala nama-opioid aqondise ukuze adale imiphumela yawo yokuvuza. Lokhu kuyenza ibe umuthi oqinile ngokulinganisela onikeza ukuvikeleka okuthembekile.

Uma uphuza utshwala noma usebenzisa ama-opioid ngenkathi use-naltrexone, ngeke uzwe imizwa ejwayelekile emnandi. Kunalokho, lezi zinto ziba ezingasebenzi ekukhiqizeni i-euphoria noma ukuphumula.

Umuthi awukwenzi uzizwe ugula noma ungaphilile uma uhlangana nalezi zinto. Vele ususa okuhlangenwe nakho okuvuza okuvame ukushayela ukuqhubeka kokusetshenziswa.

Lo mphumela wokuvimba uhlala inyanga yonke phakathi kwemijovo. Ama-receptor e-opioid obuchopho bakho ahlala ematasa yi-naltrexone, enikeza ukuvikeleka okuqhubekayo ngisho noma unezikhathi zobuthakathaka noma ukulangazelela okuqinile.

Kufanele Ngiyithathe Kanjani I-Naltrexone Intramuscular Injection?

Uzothola umjovo wakho we-naltrexone ehhovisi likadokotela wakho noma emtholampilo kanye njalo emavikini amane. Umhlinzeki wezempilo uzokunika umjovo emsipheni wakho wezinqulu, eshintshana izinhlangothi ngomjovo ngamunye.

Ngaphambi kokuqokwa kwakho, ungaqhubeka udla ngokujwayelekile futhi akudingeki ukuthi ugweme noma yikuphi ukudla okuthile. Nokho, ukugqoka izingubo ezikhululekile kungenza inqubo yokujova ikhululeke kakhulu.

Umjovo ngokwawo uthatha imizuzu embalwa nje, nakuba kungase kudingeke ukuthi uhlale isikhathi esifushane sokubuka. Eminye imitholampilo ithanda ukuqapha iziguli imizuzu engu-15-30 ngemuva komjovo ukuze kuqinisekiswe ukuthi akukho okwenzeka ngokushesha.

Kuzodingeka ukuthi uhlele ukuqokwa kwakho okulandelayo ngaphambi kokushiya umtholampilo. Ukugcina isimiso esiqhubekayo sanyanga zonke kusiza ukugcina amazinga emithi aqinile ohlelweni lwakho.

Ngizoyithatha isikhathi esingakanani i-Naltrexone?

Abantu abaningi baqhubeka nokujovwa kwe-naltrexone okungenani izinyanga eziyi-6-12, nakuba abanye bezuza ezikhathini zokwelashwa ezinde. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngenqubekela phambili yakho yokululama.

Ubude bokwelashwa buvame ukuncika ezimweni zakho, uhlelo lokusekela, nokuthi ululama kahle kangakanani. Abanye abantu bathola ukuthi badinga ukusekelwa okuqhubekayo iminyaka eminingi, kanti abanye bangashintshela kwezinye izinhlobo zokwelashwa.

Umhlinzeki wakho wezempilo uzohlola njalo inqubekela phambili yakho futhi axoxe ngokuthi ngabe ukuqhubeka nokwelashwa kunengqondo yini esimweni sakho. Lezi zingxoxo zivame ukwenzeka njalo ezinyangeni ezimbalwa ngesikhathi sokuqokwa kwakho okuvamile.

Khumbula ukuthi ukuyeka i-naltrexone kufanele ngaso sonke isikhathi kube yisinqumo esihleliwe esenziwa ngesiqondiso sikadokotela wakho. Ukuyeka ukwelashwa kungazelelwe kungakushiya ubuthakathaka ekuphindweni ngaphandle kwezinhlelo zokusekela ezifanele.

Yiziphi Imiphumela Eceleni ye-Naltrexone?

Abantu abaningi bayakubekezelela ukujovwa kwe-naltrexone kahle, kodwa ungase uhlangabezane nemiphumela ethile eceleni, ikakhulukazi emasontweni ambalwa okuqala. Le miphumela ivame ukulawuleka futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nawa amanye imiphumela ejwayelekile ongase uyibone:

• Ukuphendula kwendawo yokujova njengobuhlungu, ukuvuvukala, noma ububomvu
• Isicanucanu noma isisu esibuhlungu
• Ikhanda elibuhlungu
• Isiyezi noma ukukhathala
• Ukungalali kahle
• Ukuncipha kwesifiso sokudla
• Ubuhlungu bemisipha noma amalunga

Le miphumela ejwayelekile eceleni ivame ukuhlala izinsuku ezimbalwa kuya evikini ngemuva kokujova ngakunye. Abantu abaningi bayayithola itholeka futhi ilawuleka ngezinyathelo zokunethezeka ezilula.

Imiphumela engavamile kodwa ebucayi ingenzeka ngezikhathi ezithile, futhi kufanele uxhumane nodokotela wakho uma uhlangabezana nanoma yiziphi izimpawu ezikhathazayo:

• Ukusabela okukhulu endaweni yokujova ngobuhlungu obukhulayo noma ukufudumala
• Izimpawu zokucindezeleka noma izinguquko zemizwa
• Isicanucanu esikhulu noma ukuhlanza
• Ukukhathala okungavamile noma ubuthakathaka
• Ubuhlungu besisu noma ukungakhululeki

Imiphumela emibi engavamile kodwa ebucayi ihlanganisa izinkinga zesibindi, nakuba lokhu kungavamile ngohlobo lomjovo. Udokotela wakho uzoqapha ukusebenza kwesibindi sakho ngokuhlolwa kwegazi ngezikhathi ezithile.

Ngokungavamile kakhulu, abanye abantu bathuthukisa ukusabela okukhulu komzimba ku-naltrexone. Izimpawu zihlanganisa ubunzima bokuphefumula, ukuvuvukala kobuso noma umphimbo, noma ukuqubuka okubanzi. Lokhu kudinga ukunakekelwa kwezempilo ngokushesha.

Ubani Ongafanele Athole I-Naltrexone?

I-Naltrexone ayiphephile kuwo wonke umuntu, futhi izimo ezithile zenza lo muthi ungafaneleki noma uyingozi. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokubhala lo muthi.

Akufanele uthole imijovo ye-naltrexone uma:

• Njengamanje usebenzisa ama-opioid noma awukabi mahhala kuma-opioid okungenani izinsuku eziyi-7-10
• Une-liver disease enkulu noma ukwehluleka kwesibindi
• Unokungezwani komzimba ku-naltrexone noma yiziphi izithako emjovweni
• Ukhulelwe noma uncelisa
• Une-kidney disease enkulu

Udokotela wakho uzosebenzisa ukuqapha okwengeziwe uma unezimo ezithile zempilo ezidinga ukuqashwa ngokucophelela ngesikhathi sokwelashwa.

Abantu abanezinkinga zesibindi ezincane bangase babe ngabazongenela ukwelashwa, kodwa bazodinga ukuqashwa kaningi ngokuhlolwa kwegazi. Udokotela wakho uzoqaphela izinzuzo ngokumelene nezingozi kulezi zimo.

Uma uthatha imithi ye-opioid kadokotela yokulawula ubuhlungu, uzodinga ukusebenza nodokotela bakho ukuze uthuthukise uhlelo oluhlukile lokuphatha ubuhlungu ngaphambi kokuqala i-naltrexone.

Amagama Omkhiqizo we-Naltrexone

Igama lomkhiqizo elivamile le-naltrexone intramuscular injection yi-Vivitrol. Lena yinguqulo odokotela abaningi abayibhala futhi izinkampani zomshuwalense ngokuvamile ziyayihlanganisa.

I-Vivitrol iqukethe i-naltrexone engu-380 mg emjovweni ngamunye wanyanga zonke. Umuthi uza njengempushana exhutshwa ngumhlinzeki wakho wezempilo ngolwelo olukhethekile ngaphambi nje kokukujova.

Amanye amakhemisi okuhlanganisa angase alungise ezinye izinhlobo ze-naltrexone esebenza isikhathi eside, kodwa i-Vivitrol isahlala iyindlela efundwe kakhulu futhi ebekwe odokotela. Udokotela wakho cishe uzoqala ngale fomula esungulwe kahle.

Ezinye Izindlela Zokwelapha Nge-Naltrexone

Eminye imithi eminingana ingasiza ngokuphazamiseka kokusetshenziswa kotshwala noma i-opioid uma i-naltrexone ingakulungele. Udokotela wakho angaxoxa ngalezi zinketho ngokusekelwe ezidingweni zakho kanye nezimo zakho.

Ngokuphazamiseka kokusetshenziswa kotshwala, ezinye izindlela zokwelapha zihlanganisa i-acamprosate, esiza ukunciphisa ukulangazelela, kanye ne-disulfiram, ebangela ukusabela okungathandeki uma uphuza. Abanye abantu bazuza futhi ku-topiramate noma i-gabapentin.

Ngokuphazamiseka kokusetshenziswa kwe-opioid, i-buprenorphine kanye ne-methadone ziyizindlela eziphumelelayo. Le mithi isebenza ngendlela ehlukile kune-naltrexone ngokuvula ingxenye yezamukeli ze-opioid kunokuba zizivimbele ngokuphelele.

Abanye abantu benza ngcono nge-naltrexone yomlomo yansuku zonke uma bekhetha ukungatholi imijovo yanyanga zonke. Abanye bangazuza ezindleleni zokuhlanganisa ezihlanganisa ukwelulekwa, amaqembu okusekela, kanye nezinguquko zokuphila.

Ingabe i-Naltrexone Ingcono Kune-Buprenorphine?

Kokubili i-naltrexone ne-buprenorphine kuyasebenza ekwelapheni ukuphazamiseka kokusetshenziswa kwe-opioid, kodwa zisebenza ngezindlela ezihlukene futhi zifanele abantu abahlukene. Akukho muthi owodwa ongcono kunomunye.

I-Naltrexone ivimba ngokuphelele imiphumela ye-opioid, okuyinto abanye abantu abayithandayo ngoba ayibangeli ukuncika ngokomzimba. Nokho, kufanele ube ngaphandle ngokuphelele kwe-opioid ngaphambi kokuqala ukwelashwa, okungaba yinselele.

I-Buprenorphine ivula izingxenye zamareceptor e-opioid, okusiza ukuphatha izimpawu zokuhoxisa nokulangazelela ngenkathi ivimba imiphumela yama-opioid amanye. Ungaqala lo muthi ngenkathi usahlangabezana nokuhoxiswa, okwenza ushintsho lube lula.

Udokotela wakho uzokusiza ukhethe ngokusekelwe esimweni sakho ngasinye, okuhlanganisa ukuthi usenesikhathi esingakanani uqotho, uhlelo lwakho lokusekela, nezintandokazi zakho siqu mayelana nezindlela zokwelapha.

Imibuzo Evame Ukubuzwa Mayelana ne-Naltrexone

Q1. Ingabe i-Naltrexone iphephile kubantu abanokucindezeleka?

I-Naltrexone ingasetshenziswa ngokuphepha kubantu abanokucindezeleka, kodwa idinga ukuqapha okucophelelayo. Abanye abantu bahlangabezana nezinguquko zemizwa lapho beqala i-naltrexone, ngakho udokotela wakho uzofuna ukulandelela impilo yakho yengqondo eduze.

Uma usebenzisa ama-antidepressants, i-naltrexone ngokuvamile ayiphazamisi le mithi. Kodwa-ke, udokotela wakho angase alungise ukwelashwa kwakho kokucindezeleka ukuze aqinisekise ukuthi uthola ukunakekelwa okungcono kakhulu kuzo zombili izimo.

Kubalulekile ukutshela umhlinzeki wakho wezempilo nganoma yimuphi umlando wokucindezeleka noma imicabango yokuzibulala. Banganikeza ukwesekwa okwengeziwe nokuqapha ngesikhathi sokwelashwa kwakho.

Q2. Kufanele ngenzeni uma ngisebenzisa i-Naltrexone eningi ngengozi?

Njengoba i-naltrexone inikezwa njengomjovo wanyanga zonke ngabahlinzeki bezempilo, ukweqisa ngengozi akuvamile kakhulu. Umuthi ulinganiswa ngokucophelela futhi unikezwe ezindaweni zomtholampilo.

Uma ngandlela thize uthole i-naltrexone eningi, ungaqhubeka nokuba nemiphumela emibi enamandla njengokucasuka, isiyezi, noma ikhanda. Xhumana nodokotela wakho ngokushesha uma ukholelwa ukuthi uthole umthamo ongafanele.

Into ebaluleke kakhulu ukufuna ukunakekelwa kwezempilo ngokushesha. Umhlinzeki wakho wezempilo angakuqapha nganoma yiziphi izinkinga futhi anikeze ukunakekelwa okusekelayo uma kudingeka.

Q3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Naltrexone?

Uma uphuthelwa umjovo wakho wanyanga zonke we-naltrexone, xhumana nodokotela wakho ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Imiphumela yokuvikela yomuthi iqala ukuncipha ngemva kwezinsuku ezingaba ngu-30.

Ungalindi kuze kube yilapho uqokwe khona ngokulandelayo uma usuvele udlule isikhathi. Udokotela wakho angase afune ukukubona ngokushesha ukuze ugcine ukwelashwa okuqhubekayo futhi axoxe nganoma yiziphi izinselelo obhekene nazo.

Ukuphuthelwa imithamo kungakhuphula ingozi yakho yokuphindela emuva, ngakho kubalulekile ukubuyela emkhondweni ngokushesha. Ithimba lakho lokunakekelwa kwezempilo lingakusiza ukuthi uthuthukise amasu okukhumbula ama-aphoyintimenti esikhathi esizayo.

Q4. Ngingayeka nini ukuthatha i-Naltrexone?

Isinqumo sokuyeka i-naltrexone kufanele senziwe ngaso sonke isikhathi ngesiqondiso sikadokotela wakho. Abantu abaningi baqhubeka nokwelashwa okungenani izinyanga eziyi-6-12, nakuba abanye bezuza ezikhathini ezingaphezu kwalokho.

Udokotela wakho uzocabangela izinto ezinjengentuthuko yakho yokululama, uhlelo lokusekela, kanye nemigomo yakho siqu lapho exoxa ngokuyeka. Bangase batusa ukuhlukanisa kancane kancane imijovo noma ukushintshela kwezinye izinhlobo zokusekela.

Ngaphambi kokuyeka i-naltrexone, qiniseka ukuthi unezindlela eziqinile zokubhekana nezimo kanye nezinhlelo zokusekela endaweni. Ithimba lakho lokunakekelwa kwezempilo lingakusiza ukuthi uthuthukise uhlelo olubanzi lokugcina ukululama kwakho.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Naltrexone?

Ngenkathi i-naltrexone ivimba imiphumela eklomelisayo yotshwala, ukuphuza ngenkathi usebenzisa lo muthi akutuswa. Umuthi unciphisa imiphumela emnandi yotshwala, kodwa usengase uhlangabezane nokuphazamiseka kanye nezingozi zempilo.

Abanye abantu bathola ukuthi utshwala bunambitheka ngendlela ehlukile noma alukhanga kangako ngenkathi besebenzisa i-naltrexone. Lokhu empeleni yindlela umuthi osiza ngayo ukunciphisa ukuziphatha kokuphuza ngokuhamba kwesikhathi.

Uma uphuza ngenkathi usebenzisa i-naltrexone, ngeke uthole i-buzz ejwayelekile, kodwa usengase uhlangabezane nama-hangover, ukwahlulela okubi, nezinye izinkinga ezihlobene notshwala. Umgomo uwukugcina ukuzithiba ngokuphelele ukuze uthole imiphumela engcono kakhulu.