Yini i-Naratriptan: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Naratriptan iyimithi kadokotela eyenzelwe ngqo ukwelapha ikhanda elibuhlungu le-migraine uma liqala. Ingaphansi kohlu lwemithi olubizwa ngokuthi ama-triptans, asebenza ngokugxila kumakhemikhali athile obuchopho abangela ubuhlungu be-migraine. Cabanga ngayo njengemithi yokuhlenga eqondiwe engasiza ekumisa i-migraine ngokushesha, kunokuthi kube yinto oyithathayo ukuvimbela ama-migraine ukuthi angabi khona.

Yini i-Naratriptan?

I-Naratriptan iyimithi ye-triptan odokotela abayibhala ukwelapha ukuhlaselwa kwe-migraine okubukhali. Yilokho esikubiza ngokuthi ukwelashwa okuyekayo, okusho ukuthi kusebenza ukumisa i-migraine esivele iqale kunokuvimbela ezinye ezizayo.

Le mithi iza ngamaphilisi omlomo owathatha ngomlomo lapho uzwa i-migraine iqala. I-Naratriptan ithathwa njenge-selective serotonin receptor agonist, okusho ukuthi isebenza kuma-receptors athile ebuchosheni bakho ukunciphisa ubuhlungu be-migraine nezimpawu ezihambisanayo.

Le mithi yathuthukiswa ngqo kubantu abanezinhlungu zekhanda eziphakathi nendawo kuya kwezinkulu ze-migraine ezinoma ngaphandle kwe-aura. Ilusizo ikakhulukazi kulabo abadinga inketho ye-triptan ehlala isikhathi eside uma iqhathaniswa neminye imithi ekulesi sigaba.

Yini i-Naratriptan Esetshenziselwa Yona?

I-Naratriptan isetshenziswa ikakhulukazi ukwelapha izinhlungu zekhanda eziphakathi nendawo kuya kwezinkulu ze-migraine kubantu abadala. Yenzelwe ukumisa ubuhlungu be-migraine nezimpawu ezihlobene uma seziqaliwe, hhayi ukuvimbela ama-migraine esikhathi esizayo.

Le mithi isebenza kahle kakhulu uma ithathwa ekuqaleni kwezimpawu ze-migraine. Lokhu kufaka phakathi ubuhlungu bekhanda obugxumayo, isicanucanu, ukuhlanza, nokuzwela ekukhanyeni nasezwini okuvame ukuhambisana nama-migraine.

Odokotela bangabhala i-naratriptan kubantu abanezinhlungu ze-migraine ezinoma ngaphandle kwe-aura. I-Aura ibhekisela ekuphazamisekeni okubonakalayo, imizwa yokuluma, noma ezinye izimpawu ze-neurological abanye abantu abazitholayo ngaphambi kokuthi ikhanda labo liqale.

Naratriptan

Nakuba i-naratriptan ivunyelwe ngokuqondile ama-migraines, ngokuvamile ayisetshenziswa ngamakhanda aqinile noma ezinye izinhlobo zekhanda. Udokotela wakho uzokusiza ukuthi unqume ukuthi lo muthi ulungele yini uhlobo lwakho oluthile lekhanda.

Isebenza Kanjani I-Naratriptan?

I-Naratriptan isebenza ngokugxila kuma-receptors athile e-serotonin ebuchosheni bakho nasemithanjeni yegazi. Uma une-migraine, imithambo yegazi ethile ekhanda lakho iyavuvukala futhi yanda, okufaka isandla ebuhlungwini obuzwayo.

Umuthi ubopha kuma-receptors e-serotonin futhi ubangele le mithambo yegazi evuvukele ukuthi inciphe ibuyele osayizini yayo ovamile. Lokhu kusiza ukunciphisa ukuvuvukala nobuhlungu obuhambisana ne-migraine yakho.

I-Naratriptan ithathwa njengomuthi we-triptan oqinile ngokulinganisela. Ivame ukusebenza kancane kunezinye izinhlobo ze-triptans kodwa ngokuvamile inikeza ukukhululeka okuhlala isikhathi eside, okungaba usizo uma ama-migraines akho ngokuvamile ehlala isikhathi eside.

Umuthi futhi usiza ukunciphisa ezinye izimpawu ze-migraine njengokucasuka kwesisu nokuzwela ekukhanyeni nasezwini. Lokhu kwenzeka ngoba kuthinta izindlela zemizwa ezithwala lezi zimpawu zobuhlungu nezinzwa ebuchosheni bakho.

Kufanele Ngiyithathe Kanjani I-Naratriptan?

Thatha i-naratriptan ngendlela udokotela wakho ayikuyala ngayo, ngokuvamile ngokushesha nje lapho uqaphela izimpawu ze-migraine ziqala. Umuthi usebenza kahle kakhulu uma uthathwa ekuqaleni kwenqubo ye-migraine, ngakho-ke ungalindi ukuthi ubuhlungu bube bukhulu.

Ungathatha amaphilisi e-naratriptan ngaphandle noma ngaphandle kokudla, nakuba ukuwathatha nokudla kungasiza ukunciphisa noma yikuphi ukuphazamiseka kwesisu. Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele - ungayichobozi, uyihlafune, noma uyiphule.

Uma i-migraine yakho ingathuthuki ngemva komthamo wokuqala, ungase ukwazi ukuthatha umthamo wesibili, kodwa linda okungenani amahora angu-4 phakathi kwemithamo. Ungalokothi uthathe amaphilisi angaphezu kwama-2 esikhathini esiyizinsuku ezingama-24 ngaphandle uma uqondiswe ngokuqondile udokotela wakho.

Zama ukuthatha i-naratriptan egumbini elizolile, elimnyama uma kungenzeka, ngoba lokhu kungasiza umuthi ukuthi usebenze ngempumelelo. Phuza futhi ugweme ukukhanya okukhanyayo noma imisindo ephezulu ngenkathi umuthi usebenza.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Naratriptan?

I-Naratriptan yenzelwe ukusetshenziswa kwesikhashana ukwelapha izigameko ze-migraine ngazinye, hhayi ukuvimbela nsuku zonke noma isikhathi eside. Kufanele uyithathe kuphela uma uhlangabezana nokuhlaselwa kwe-migraine kwangempela.

Abantu abaningi bathola ukukhululeka kungakapheli amahora angu-2-4 ngemuva kokuthatha i-naratriptan, nakuba abanye bengase babone ukuthuthuka ngokushesha. Imiphumela ivame ukuhlala amahora amaningi, yingakho lo muthi uvame ukukhethwa kubantu abane-migraines ehlala isikhathi eside.

Uma uzithola udinga ukusebenzisa i-naratriptan izikhathi ezingaphezu kuka-2-3 ngesonto, khuluma nodokotela wakho mayelana nokwelashwa kwe-migraine okuvikelayo. Ukusebenzisa ngokweqile noma yimuphi umuthi we-triptan empeleni kungaholela ekubeni nekhanda elibangelwa ukusetshenziswa ngokweqile kwemithi.

Udokotela wakho uzoqapha ukuthi i-naratriptan ikusebenzela kahle kangakanani futhi angase alungise uhlelo lwakho lokwelashwa uma kudingeka. Abanye abantu bayayisebenzisa ngezikhathi ezithile iminyaka eminingi, kanti abanye bangashintshela ekwelashweni okuhlukile ngokusekelwe kumaphethini abo e-migraine.

Yiziphi Imiphumela Eceleni Ye-Naratriptan?

Njengayo yonke imithi, i-naratriptan ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe uqiniseka ngokwengeziwe mayelana nokuthatha lo muthi.

Imiphumela emibi evame kakhulu ivame ukuba milde futhi yesikhashana. Lokhu kungabandakanya:

• Ukozela noma ukukhathala
• Isiyezi
• Isicanucanu (nakuba lokhu kungase futhi kuvele ku-migraine yakho)
• Umlomo owomile
• Ubuthakathaka bemisipha noma ukusinda
• Umuzwa ofudumele noma wokuluma
• Ukuqina komphimbo noma ukucindezela

Abanye abantu bahlangabezana nalokho okubizwa ngokuthi

Imiphumela emibi kakhulu ayivamile kodwa kubalulekile ukuyiqaphela. Xhumana nodokotela wakho ngokushesha uma uhlangabezana nobuhlungu besifuba, ukuphefumula kanzima, ikhanda elibuhlungu elingazelelwe elihlukile ku-migraine yakho ejwayelekile, noma izimpawu zokushaywa unhlangothi njengobuthakathaka obungazelelwe noma ubunzima bokukhuluma.

Ngezikhathi ezingavamile, i-naratriptan ingabangela izinkinga zenhliziyo ezinzima, ikakhulukazi kubantu abanezimo zenhliziyo ezikhona. Yingakho udokotela wakho ezobuza ngempilo yenhliziyo yakho ngaphambi kokukuchazela lo muthi.

Ubani Ongafanele Athatha I-Naratriptan?

I-Naratriptan ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuchazela. Izimo eziningana zenza lo muthi ungafaneleki noma uyingozi.

Akufanele uthathe i-naratriptan uma unezimo zenhliziyo ezithile. Lokhu kufaka phakathi:

• Isifo semithambo yenhliziyo noma umlando wokuhlaselwa yinhliziyo
• Umfutho wegazi ophezulu ongagadiwe
• Ukushaya kwenhliziyo okungajwayelekile
• Umlando wokushaywa unhlangothi noma i-mini-stroke
• Isifo semithambo ye-peripheral

Abantu abanezifo ezinzima zesibindi noma izinso kufanele futhi bagweme i-naratriptan, njengoba lezi zitho zisiza ukucubungula umuthi. Uma unezinkinga zesibindi noma izinso ezilula, udokotela wakho angase akuchazele umthamo ophansi.

I-Naratriptan ayinconyelwe abantu abaneminyaka engaphezu kwengama-65 noma ngaphansi kweminyaka eyi-18 ubudala, njengoba ukuphepha kula maqembu obudala kungakazinziswa kahle. Abesifazane abakhulelwe noma abancelisa ngamabele kufanele baxoxe ngezindlela ezingezinye nomhlinzeki wabo wezempilo.

Uma uthatha ama-antidepressants athile, ikakhulukazi ama-MAO inhibitors, uzodinga ukulinda okungenani izinsuku eziyi-14 ngemva kokuwayeka ngaphambi kokusebenzisa i-naratriptan. Hlala utshela udokotela wakho ngayo yonke imithi oyithathayo.

Amagama Omkhiqizo we-Naratriptan

I-Naratriptan itholakala ngaphansi kwamagama amaningana omkhiqizo, i-Amerge iyona ejwayelekile e-United States. Le nguqulo yegama lomkhiqizo iqukethe isithako esifanayo esisebenzayo njengamaphilisi e-naratriptan ajwayelekile.

Noma ngabe uthola igama lomkhiqizo noma i-generic naratriptan, umuthi usebenza ngendlela efanayo futhi uqukethe isithako esifanayo esisebenzayo. Izinhlobo ze-Generic ngokuvamile zibiza kancane futhi zisebenza kahle njengenketho yegama lomkhiqizo.

Ikhemisi lakho lingashintsha ngokuzenzakalelayo i-generic naratriptan ngegama lomkhiqizo ngaphandle kokuthi udokotela wakho acele ngokuqondile inguqulo yegama lomkhiqizo. Zombili izinketho ziphephile futhi zisebenza kahle ekwelapheni i-migraines.

Ezinye izindlela zokwelapha i-Naratriptan

Uma i-naratriptan ingasebenzi kahle kuwe noma ibangela imiphumela emibi, kukhona izindlela eziningi zokwelapha ezitholakalayo. Udokotela wakho angakusiza ukuthi uthole inketho engcono kakhulu ngokusekelwe ezidingweni zakho ezithile kanye nomlando wakho wezokwelapha.

Eminye imithi ye-triptan ihlanganisa i-sumatriptan, i-rizatriptan, kanye ne-eletriptan. Ngayinye inezici ezihlukile kancane mayelana nokuthi isebenza ngokushesha kangakanani nokuthi ihlala isikhathi esingakanani. Abanye abantu basabela kangcono ku-triptan eyodwa kunenye.

Izinketho ezingezona ze-triptan zihlanganisa ama-NSAID afana ne-ibuprofen noma i-naproxen, engasebenza kahle kuma-migraines alula kuya kwamaphakathi. Imithi kadokotela efana ne-ergotamines noma ama-CGRP antagonists amasha angase futhi abe ezinye izindlela ezifanele.

Kubantu abangakwazi ukuthatha ama-triptans ngenxa yezimo zenhliziyo, udokotela wakho angase ancome imithi yokuvimbela esikhundleni salokho. Lokhu kufaka phakathi imithi ethile yokucindezela igazi, ama-antidepressants, noma imithi elwa nokuhlaselwa enganciphisa imvamisa ye-migraine.

Ingabe i-Naratriptan ingcono kune-Sumatriptan?

Kokubili i-naratriptan ne-sumatriptan ziyimithi ye-triptan esebenzayo, kodwa zinezici ezihlukene ezingenza enye ifaneleke kakhulu kuwe kunenye. Akukho ngisho okukodwa okungcono ngokujwayelekile - kuya ngezidingo zakho ngazinye nokusabela.

I-Sumatriptan ngokuvamile isebenza ngokushesha kune-naratriptan, ngokuvamile inikeza ukukhululeka phakathi kwemizuzu engama-30 kuya emahoreni amabili. Kodwa-ke, i-naratriptan ivame ukunikeza ukukhululeka okuhlala isikhathi eside futhi kungenzeka ukuthi ayibangeli ukuphindeka kwekhanda kungakapheli amahora angama-24.

Mayelana nemiphumela emibi, i-naratriptan ngokuvamile ibangela imiphumela emibi embalwa kune-sumatriptan. Abantu ababa nemiphumela emibi ebalulekile nge-sumatriptan bavame ukubekezelela i-naratriptan kangcono.

Uma une-migraines ehlala isikhathi eside noma uvame ukuba nokubuyela emuva kwekhanda, i-naratriptan ingase ibe yindlela engcono. Uma udinga ukukhululeka okusheshayo futhi ungenandaba nokuthatha umthamo wesibili, i-sumatriptan ingase ifaneleke kakhulu.

Imibuzo Evame Ukubuzwa Nge-Naratriptan

Ingabe i-Naratriptan Iphephile Kubantu Abane-High Blood Pressure?

I-Naratriptan ingaphepha kubantu abane-high blood pressure elawulwa kahle, kodwa idinga ukugadwa kwezokwelapha ngokucophelela. Umuthi ungakhuphula okwesikhashana umfutho wegazi, ngakho udokotela wakho uzodinga ukuhlola impilo yakho yenhliziyo ngaphambi kokuyinquma.

Uma umfutho wakho wegazi ungalawulwa noma uphakeme kakhulu, i-naratriptan ayinconyelwe. Udokotela wakho angase afune ukuqapha umfutho wakho wegazi eduze lapho uqala ukuthatha lo muthi.

Abantu abane-high blood pressure elula kuya kweliphakathi abathatha imithi yomfutho wegazi basengakwazi ukusebenzisa i-naratriptan ngokuphepha. Okubalulekile ukuba nomfutho wegazi olawulwa kahle ngaphambi kokuqala noma yimuphi umuthi we-triptan.

Ngingenzani Uma Ngenhlanhla Ngithatha I-Naratriptan Eningi Kakhulu?

Uma ngengozi uthatha i-naratriptan eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungakhuphula ingozi yakho yemiphumela emibi engathi sína, ikakhulukazi izinkinga ezihlobene nenhliziyo.

Izimpawu ze-naratriptan overdose zingabandakanya isiyezi esikhulu, ubuhlungu besifuba, ubunzima bokuphefumula, noma ukushaya kwenhliziyo okungajwayelekile. Ungalindi ukubona ukuthi izimpawu ziyavela yini - funa ukwelashwa ngokushesha.

Ukuvimbela i-overdose ngengozi, ungalokothi uthathe amaphilisi angaphezu kwama-2 emahoreni angama-24, futhi ngaso sonke isikhathi linda okungenani amahora ama-4 phakathi kwemithamo. Gcina umkhondo wokuthi uthatha nini umthamo ngamunye ukuze ugweme ukudideka.

Kumele Ngenzeni Uma Ngingaphuthelwa Umthamo We-Naratriptan?

Njengoba i-naratriptan ithathwa njengoba idingeka ekuhlaselweni kwe-migraine, akukho isimiso sokuthatha imithi esivamile okumele silandelwe. Uthatha kuphela uma uhlangabezana ne-migraine, ngakho-ke "ukuphuthelwa umthamo" akusebenzi ngempela.

Uma uqaphela ukuthi bekufanele ngabe uyithathile i-naratriptan ngaphambi kokuba i-migraine yakho iqale, usengayithatha, nakuba ingase ingasebenzi kahle. Umuthi usebenza kahle kakhulu uma uthathwa ngesikhathi sezimpawu zokuqala ze-migraine.

Ungathathi i-naratriptan eyengeziwe ukuze ulungise ukuyithatha ngemuva kokuba bekulungile. Namathela emiyalweni yokuthatha imithi enqunyiwe kungakhathaliseki ukuthi uyithatha nini umthamo wakho wokuqala ngesikhathi sokuhlaselwa yi-migraine.

Ngingayeka Nini Ukuthatha I-Naratriptan?

Ungayeka ukuthatha i-naratriptan nganoma yisiphi isikhathi ngoba isetshenziswa kuphela njengoba idingeka ekuhlaselweni kwe-migraine. Akukho ukuhoxiswa noma inqubo yokunciphisa edingekayo ngoba awuyithathi ngokuqhubekayo.

Nokho, uma i-naratriptan ibilapha ngempumelelo ama-migraine akho, xoxa ngezindlela ezingezinye nodokotela wakho ngaphambi kokuyeka. Uzofuna ukuba nohlelo olusha lokwelapha olukhona lweziqephu ze-migraine zesikhathi esizayo.

Abanye abantu bangase bafune ukuyeka i-naratriptan uma amaphethini abo e-migraine eshintsha, uma behlangabezana nemiphumela emibi ekhathazayo, noma uma bethuthukisa izimo zezokwelapha ezingenza ama-triptan angalungi. Udokotela wakho angakusiza ukuthi ushintshele ekwelashweni okuhlukile.

Ngingayithatha I-Naratriptan Neminye Imithi?

I-Naratriptan ingasebenzisana neminye imithi eminingi, ngakho-ke kubalulekile ukutshela udokotela wakho ngakho konke okuthathayo. Ezinye izinhlanganisela zingaba yingozi futhi kufanele zigwenywe.

Akufanele uthathe i-naratriptan neminye imithi ye-triptan noma imithi equkethe i-ergot, njengoba lokhu kungandisa ingozi yemiphumela emibi engathí sina. Linda okungenani amahora angama-24 ngaphambi kokuthatha imithi ehlukene ye-triptan.

Ezinye izidambisi zokucindezeleka, ikakhulukazi ama-MAO inhibitors kanye nama-SSRIs athile, angasebenzisana ne-naratriptan. Udokotela wakho uzodinga ukubukeza ngokucophelela noma yimiphi imithi yokudambisa ukucindezeleka oyithathayo ngaphambi kokukubhalela i-naratriptan.