Yini i-Niacin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Niacin iyindlela kavithamini B3 edingwa umzimba wakho ukuze usebenze kahle. Eyaziwa nangokuthi i-nicotinic acid, le nto ebalulekile yokudla isiza ukuguqula ukudla kube amandla futhi isekela isikhumba esinempilo, imizwa, nokugaya ukudla.

Ngenkathi ungathola i-niacin ngokwemvelo ekudleni okufana nenyama, izinhlanzi, kanye nokusanhlamvu okuphelele, odokotela ngezinye izikhathi banquma imithamo ephezulu njengemithi. Le mithamo yokwelapha ingasiza ekwelapheni izimo ezithile zempilo, ikakhulu lezo ezihlobene ne-cholesterol nempilo yenhliziyo.

Yini i-Niacin Esetshenziselwa Yona?

I-Niacin isebenza ngezinhloso ezimbili eziyinhloko ngokuya ngomthamo owuthathayo. Ngemithamo ephansi, isebenza njengesithasiselo sikavithamini ukuvimbela noma ukwelapha ukuntuleka kwe-niacin, okungadala isimo esibizwa nge-pellagra.

Ngemithamo ephezulu yokunqunyelwa, i-niacin iba umuthi onamandla wokuphatha amazinga e-cholesterol. Udokotela wakho angase akunqumele ukwehlisa i-cholesterol yakho embi ye-LDL nama-triglycerides ngenkathi ekhuphula i-cholesterol yakho enhle ye-HDL.

Abanye abantu futhi basebenzisa i-niacin ukusiza ngezinkinga zokujikeleza kwegazi, nakuba lokhu kusetshenziswa kudinga ukugadwa ngokucophelela kwezokwelapha. Umuthi ungathuthukisa ukugeleza kwegazi ngokwandisa imithambo yegazi, okudala lowo muzwa othi "ukukhukhula" abantu abaningi abawuzwayo.

Isebenza Kanjani i-Niacin?

I-Niacin isebenza ngendlela ehlukile ngokuya ngokuthi uyayithatha njengovithamini noma njengomuthi we-cholesterol. Njengovithamini, isiza amaseli akho ukuthi akhiqize amandla ngokusiza ama-enzyme aqeda amafutha, ama-carbohydrate, namaprotheni.

Uma isetshenziselwa ukuphatha i-cholesterol, i-niacin isebenza ngaphezulu njengomuthi onamandla aphakathi nendawo. Isebenza ngokunciphisa ukukhiqizwa kwe-cholesterol nama-triglycerides esibindi sakho ngenkathi isiza umzimba wakho ukuthi uqhubekisele phambili la mafutha ngempumelelo.

Umuthi futhi wenza imithambo yegazi ukuthi ivuleke okwesikhashana, okuchaza umuzwa ofudumele, obhobozayo obizwa ngokuthi "i-niacin flush." Lo mphumela ujwayelekile futhi ngokuvamile awuyingozi, nakuba ungenza uzizwe ungakhululekile ekuqaleni.

Kufanele Ngiyithathe Kanjani I-Niacin?

Ukuphuza i-niacin ngendlela efanele kungenza umehluko omkhulu ekutheni uyayibekezelela kangakanani. Odokotela abaningi batusa ukuyithatha nokudla ukuze kunciphise ukuphazamiseka kwesisu futhi kunciphise umphumela wokushisa.

Ukuze uthole imiphumela emihle, thatha umthamo wakho we-niacin nokudla okuqukethe amafutha athile, njengengcezu yesinkwa esosiwe enebhotela noma inani elincane lamantongomane. Lokhu kusiza umzimba wakho ukuthi umunce umuthi ngokushelela futhi kunciphisa amathuba okungakhululeki kokugaya ukudla.

Uma uthatha i-niacin ekhishwa isikhathi eside, gwinya ithebhulethi yonke ngaphandle kokuyichoboza, ukuyihlafuna, noma ukuyiqhekeza. Ukumbozwa okukhethekile kuklanyelwe ukukhipha umuthi kancane usuku lonke, okusiza ukunciphisa imiphumela emibi.

Abantu abaningi bathola ukuthi ukuthatha i-niacin ngesikhathi sokulala kusebenza kahle, ikakhulukazi lapho beqala ukwelashwa. Lesi sikhathi sikuvumela ukuthi ulale ngesikhathi sokuqala sokushisa ngenkathi umzimba wakho uzivumela emuthini.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Niacin?

Ubude bokwelashwa nge-niacin buxhomeke ngokuphelele ekutheni uyithatheleni. Uma uyisebenzisa njengesithasiselo se-vitamin sokuntuleka, ungase idinge kuphela amasonto ambalwa noma izinyanga kuze kube yilapho amazinga akho ejwayelekile.

Ukuze ulawule i-cholesterol, i-niacin ngokuvamile iyisibopho sesikhathi eside. Udokotela wakho cishe uzofuna ukuthi uyithathe izinyanga noma iminyaka, kuye ngokuthi isebenza kahle kangakanani kuwe nokuthi amazinga akho e-cholesterol asabela kanjani.

Umhlinzeki wakho wezempilo uzoqapha inqubekela phambili yakho ngezivivinyo zegazi ezivamile, ngokuvamile njalo ngamaviki angu-6 kuya kwangu-12 ekuqaleni, bese kuba njalo uma amazinga akho ezinzile. Lezi zivivinyo zisiza ukunquma ukuthi umuthi uyasebenza yini nokuthi ngabe kukhona yini okudingeka kulungiswe.

Ungayeki ukuthatha i-niacin kadokotela ngokuphazima kweso ngaphandle kokukhuluma nodokotela wakho kuqala. Amazinga akho e-cholesterol angabuyela esimweni sawo sangaphambilini ngokushesha uma uyeka imithi.

Yiziphi Izimo Ezingezinhle Ze-Niacin?

I-Niacin ingabangela imiphumela eminingi engemihle, kusukela kokulula nokwesikhashana kuya ezintweni ezinzima ezidinga ukunakekelwa kwezokwelapha. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiseleleke futhi uqiniseka ngemithi yakho.

Umphumela ovamile ongase uwuthole ubizwa ngokuthi "i-niacin flush." Lokhu kudala umuzwa ofudumele, oqhumayo obomvu ebusweni bakho, entanyeni, futhi ngezinye izikhathi esifubeni sakho nasezingalweni zakho. Ngenkathi kungase kuzwakale kukhathaza ekuqaleni, lokhu kusabela ngokuvamile akulimazi futhi kuvame ukuncipha njengoba umzimba wakho ujwayela imithi emasontweni amaningana.

Nawa ama-side effects avamile abantu abawatholayo nge-niacin:

• Ukubomvu kwesikhumba nokufudumala, ikakhulukazi ebusweni nasentanyeni
• Ukuqina noma imizwa yokuluma
• Ukuphazamiseka kwesisu noma isicanucanu
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Ikhanda elibuhlungu emasontweni ambalwa okuqala okwelashwa
• Ukuqunjelwa okulula noma ukuphazamiseka kokugaya

Le miphumela evamile ivamise ukuthuthuka emasontweni ambalwa njengoba umzimba wakho ujwayela imithi. Ukuthatha i-niacin nokudla nokuqala ngomthamo ophansi kungasiza ekunciphiseni lezi zinto.

Abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezokwelapha ngokushesha. Ngenkathi lokhu kwenzeka kaningi, kubalulekile ukwazi ukuthi yiziphi izimpawu zokuxwayisa okufanele uziqaphele.

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína:

• Ubuhlungu obukhulu besisu noma isicanucanu esiqhubekayo
• Ukuphuzi kwesikhumba sakho noma amehlo (i-jaundice)
• Umchamo onombala omnyama noma izitulo ezinombala okhanyayo ngokungavamile
• Ubuhlungu bemisipha noma ubuthakathaka, ikakhulukazi uma kuhambisana nomkhuhlane
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Isiyezi esikhulu noma ukuquleka
• Ukuphuma kwegazi okungavamile noma ukulimala

Lezi zimpawu zingase zibonise izinkinga zesibindi, ukulimala kwemisipha, noma ezinye izinkinga ezingathi sína ezidinga ukuhlolwa kwezokwelapha okusheshayo. Udokotela wakho angasiza ekunqumeni ukuthi lezi zinto zihlobene yini ne-niacin noma zingase zibe nenye imbangela.

Ubani Ongafanele Athatha I-Niacin?

Abantu abathile kufanele bagweme i-niacin noma bayisebenzise kuphela ngaphansi kokugadwa kwezokwelapha okucophelelayo. Udokotela wakho uzobukeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokukuchazela lo muthi.

Akufanele uthathe i-niacin uma unesifo sesibindi esisebenzayo noma ukunyuka okungachazeki kwama-enzyme esibindi. Umuthi ungafaka ingcindezi eyengeziwe esibindini sakho, okungenzeka ukuthi kwenze izinkinga zesibindi ezikhona zibe zimbi kakhulu.

Abantu abanezilonda eziqhubekayo nabo kufanele bagweme i-niacin, njengoba ingakhuphula ukukhiqizwa kwe-asidi yesisu futhi yenze izimpawu zesilonda zibe zimbi kakhulu. Uma unomlando wezilonda, udokotela wakho uzodinga ukukala izinzuzo ngokumelene nezingozi ngokucophelela.

Nawa amanye amazinga angase enze i-niacin ingafaneleki noma idinge ukuqapha okukhethekile:

• Isifo sezinso esibi noma i-dialysis
• Ukuphuma kwegazi okusebenzayo
• Umfutho wegazi ophansi kakhulu
• Ukuhlaselwa yinhliziyo kwamuva noma isimo senhliziyo esingazinzile
• Isifo sikashukela (i-niacin ingathinta amazinga kashukela egazini)
• I-Gout (i-niacin ingakhuphula amazinga e-uric acid)
• Isifo se-Gallbladder

Uma unesinye salezi zimo, udokotela wakho uzodinga ukukuqapha eduze noma acabangele ezinye izindlela zokwelapha. Isinqumo sokusebenzisa i-niacin sizoxhomeka empilweni yakho yonke nokuthi izinzuzo zidlula yini izingozi ezingaba khona.

Amagama Omkhiqizo we-Niacin

I-Niacin itholakala ngaphansi kwamagama amaningi omkhiqizo, ngamunye unezindlela zokwakheka ezihlukile kancane. Imikhiqizo ejwayelekile kakhulu kadokotela ihlanganisa i-Niaspan, okuyifomu elikhishwe isikhathi eside elenzelwe ukunciphisa ukukhukhula nokuthuthukisa ukubekezelelana.

Amanye amagama omkhiqizo ongahlangana nawo ahlanganisa i-Nicolar, i-Niacor, ne-Slo-Niacin. Lezi zindlela zokwakheka ezihlukene zikhipha imithi ngamanani ahlukahlukene, okungathinta kokubili ukusebenza kahle nemiphumela emibi.

Ungathola futhi i-niacin njengesithasiselo esithengiswa ngaphandle kwemvume kadokotela, kodwa le mikhiqizo ngokuvamile inesilinganiso esiphansi kakhulu kunezinhlobo zokwelashwa. Hlala uhlola nodokotela wakho ngaphambi kokushintsha phakathi kwemikhiqizo ehlukene noma izindlela zokwakheka, njengoba kungenzeka zingashintshani.

Ezinye izindlela ze-Niacin

Uma i-niacin ingasebenzi kahle kuwe noma ibangela imiphumela eminingi emibi, imithi eminingana ehlukile ingasiza ekuphatheni amazinga e-cholesterol. Udokotela wakho angakusiza ukuthi uhlole lezi zinketho ngokusekelwe esimweni sakho esithile.

Ama-Statins avame ukuba yinto yokuqala yokukhetha ukuphathwa kwe-cholesterol futhi ahlanganisa imithi efana ne-atorvastatin, i-simvastatin, ne-rosuvastatin. Le mithi isebenza ngendlela ehlukile kune-niacin futhi ngokuvamile ibekezeleleka kahle ngabantu abaningi.

Ezinye izindlela zokwelapha zihlanganisa ama-bile acid sequestrants afana ne-cholestyramine, noma imithi emisha efana ne-PCSK9 inhibitors. Inketho ngayinye inezinzuzo zayo nemiphumela emibi engaba khona, ngakho-ke ukuthola okufanele kungathatha isikhathi nokuzama.

Abanye abantu futhi bayazuza ekuhlanganiseni izinguquko zokuphila nemithi, njengokuguqulwa kokudla, ukuzivocavoca njalo, nokuphathwa kwesisindo. Umhlinzeki wakho wezempilo angasiza ekudaleni uhlelo olubanzi olusebenza kahle kakhulu ezidingweni zakho ngazinye.

Ingabe i-Niacin ingcono kune-Statins?

I-Niacin nama-statins asebenza ngendlela ehlukile ukuphatha i-cholesterol, futhi akukho noyedwa 'ongcono' kunomunye. Ukukhetha okungcono kuncike kuphrofayela yakho yezempilo ngayinye, amazinga e-cholesterol, nokuthi ukubekezelela kahle kangakanani imithi ngayinye.

Ama-Statins ngokuvamile abhekwa njengokwelashwa kokuqala kwe-cholesterol ephezulu ngoba afundwe kabanzi futhi afakazelwe ukunciphisa ingozi yesifo senhliziyo. Ngokuvamile kulula ukubekezelelwa kuno-niacin, ngemiphumela emincane ebonakalayo.

I-Niacin ingasiza ikakhulu uma une-HDL ephansi ("enhle") cholesterol, njengoba isebenza kangcono kune-statins ekuphakamiseni lawa mazinga. Kodwa-ke, kungenzeka futhi ukuthi ibangele imiphumela engathandeki efana nokubomvu.

Udokotela wakho uzocabangela izinto ezinjengengozi yakho yonke yenhliziyo, ezinye izimo zempilo, kanye nokuhlangenwe nakho kwemithi yangaphambilini lapho enquma phakathi kwalezi zinketho. Abanye abantu bangazuza ngisho nangokuthatha imithi yomibili ndawonye ngaphansi kokuqondiswa kwezokwelapha okucophelelayo.

Imibuzo Evame Ukubuzwa Mayelana ne-Niacin

Ingabe i-Niacin iphephile kubantu abanesifo sikashukela?

I-Niacin ingasetshenziswa ngabantu abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Umuthi ungabangela ukuthi amazinga kashukela egazi anyuke, okusho ukuthi ungase udinge ukulungiswa emithini yakho yesifo sikashukela.

Udokotela wakho cishe uzohlola ushukela wakho wegazi kaningi lapho uqala i-niacin futhi angase ancome ukuqapha i-glucose ekhaya kaningi. Abantu abaningi abanesifo sikashukela esilawulwa kahle bangayithatha ngokuphepha i-niacin ngaphansi kokuqondiswa kwezokwelapha okufanele.

Ngingenzani uma ngiphuthelwa ukusebenzisa i-Niacin eningi?

Uma ngengozi uthatha i-niacin eningi, xhumana nodokotela wakho noma ukulawulwa kwemithi ngokushesha. Ukuthatha amanani amaningi kungabangela ukubomvu okukhulu, ukwehla okuyingozi kwengcindezi yegazi, kanye nomonakalo wesibindi.

Ngenkathi ulindele iseluleko sezokwelapha, phuza amanzi amaningi futhi ulale phansi uma uzizwa unesiyezi noma uzoquleka. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ukwenza kanjalo ngumsebenzi wezempilo.

Ngingenzani uma ngiphuthelwa umthamo we-Niacin?

Uma uphuthelwa umthamo we-niacin, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma ingasondeli kumthamo wakho olandelayo ohleliwe. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise okushiyiwe.

Uma sekuseduze isikhathi somthamo wakho olandelayo, weqa lowo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ukuthatha imithamo emibili kungakhuphula ingozi yakho yemiphumela emibi, ikakhulukazi ukubomvu okukhulu nokungakhululeki kwesisu.

Ngingayeka nini Ukuthatha i-Niacin?

Ungalokothi uyeke ukuthatha i-niacin kadokotela ngaphandle kokuxhumana nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela amazinga akho e-cholesterol ukuthi abuyele esimweni sawo sangaphambilini phakathi namasonto ambalwa.

Udokotela wakho uzokusiza ukuthi unqume ukuthi kufanele nini ukuyeka i-niacin ngokusekelwe emazingeni akho e-cholesterol, impilo yonke, kanye nemigomo yokwelashwa. Lesi sinqumo singabandakanya ukunciphisa kancane kancane umthamo wakho kunokuyeka kungazelelwe.

Ngingakwazi yini Ukuphuza Utshwala Ngenkathi Ngithatha i-Niacin?

Kufanele ukhawulele ukusetshenziswa kotshwala ngenkathi uthatha i-niacin, njengoba kokubili kungathinta isibindi sakho. Ukuphuza utshwala kungakhuphula ingozi yokubomvu okukhulu futhi kungase kwenze eminye imiphumela emibi ibe yimbi.

Uma ukhetha ukuphuza ngezikhathi ezithile, yenza kanjalo ngokulinganisela futhi uxoxe ngokusebenzisa kwakho utshwala nodokotela wakho. Bangakunika iseluleko ngemikhawulo ephephile ngokusekelwe kumthamo wakho we-niacin kanye nesimo sempilo yakho yonke.