Yini i-Nifedipine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Nifedipine iyimithi kadokotela esiza ukuphumuza nokwandisa imithambo yakho yegazi, okwenza kube lula ukuthi inhliziyo yakho ipompe igazi emzimbeni wakho wonke. Le mithi emnene kodwa esebenzayo ingeyeqembu elibizwa ngokuthi ama-calcium channel blockers, asebenza ngokuvimba i-calcium ukuthi ingangeni emangqamuzaneni emisipha odongeni lwemithambo yakho yegazi. Uma i-calcium ivaliwe, le misipha iyaphumula, ivumela igazi ukuthi ligeleze kahle futhi kunciphisa ingcindezi ohlelweni lwakho lwe-cardiovascular.

Yini i-Nifedipine?

I-Nifedipine iyi-calcium channel blocker eqondise ngqo amaseli emisipha abushelelezi emithanjeni yakho yegazi. Cabanga ngayo njengokhiye ovimbela i-calcium ukuthi ingavuli umnyango wokuqina kwemisipha emithanjeni yakho.

Le mithi iza ngezinhlobo ezimbili eziyinhloko: amaphilisi akhishwa ngokushesha asebenza ngokushesha kanye namafomula akhishwa isikhathi eside anikeza amazinga emithi aqhubekayo usuku lonke. Izinhlobo ezikhishwa isikhathi eside zivame ukunqunywa ngoba zinikeza ukulawulwa kwengcindezi yegazi okuqhubekayo ngemithamo eminingi yansuku zonke.

Udokotela wakho angase anqume i-nifedipine njengengxenye yohlelo lokwelapha olubanzi olungabandakanya izinguquko zendlela yokuphila njengokuguqulwa kokudla nokuzivocavoca njalo. Ithathwa njengemithi esungulwe kahle esisize abantu ukuthi baphathe izimo ze-cardiovascular amashumi eminyaka.

Isetshenziselwani i-Nifedipine?

I-Nifedipine ngokuyinhloko iphatha umfutho wegazi ophezulu (i-hypertension) nezinhlobo ezithile zobuhlungu besifuba obubizwa nge-angina. Lezi yizimo ezimbili eziyinhloko lapho le mithi ibonakale isebenza kahle futhi iphephile.

Ngomfutho wegazi ophezulu, i-nifedipine isiza ukunciphisa amandla inhliziyo yakho okudingeka ukuthi ipompe igazi, okungavikela inhliziyo yakho, izinso, nezinye izitho ekulimaleni ngokuhamba kwesikhathi. Abantu abaningi abanomfutho wegazi ophezulu abazizwa izimpawu, ngakho le mithi isebenza buthule ngemuva ukuze igcine uhlelo lwakho lwe-cardiovascular lunempilo.

Uma kukhulunywa nge-angina, i-nifedipine ingasiza ekuvikeleni izigameko zobuhlungu besifuba ngokuthuthukisa ukugeleza kwegazi emsipheni wakho wenhliziyo. Lokhu kuwusizo ikakhulu kubantu ababa nokungakhululeki esifubeni ngesikhathi sokuzivocavoca noma ukucindezeleka.

Ngezinye izikhathi odokotela banikeza i-nifedipine ezinye izimo ezinjenge-Raynaud's phenomenon, lapho iminwe nezinyawo ziba zimakhaza kakhulu futhi zishintsha umbala. Kulezi zimo, umuthi usiza ukuthuthukisa ukujikeleza kulezi zindawo.

Isebenza Kanjani I-Nifedipine?

I-Nifedipine isebenza ngokuvimba iziteshi ze-calcium emangqamuzaneni emisipha ebushelelezi yemithambo yakho yegazi. Lapho i-calcium ingakwazi ukungena kula mangqamuzana, imisipha ayikwazi ukuzwana ngamandla, okwenza imithambo yakho yegazi iphumule futhi yande.

Le nqubo yenzeka kancane kancane futhi ngobumnene, yingakho i-nifedipine ithathwa njengomuthi olula uma iqhathaniswa nezinye izindlela zokwelapha umfutho wegazi ophezulu. Ukuphumula kwemithambo yegazi kunciphisa ukumelana inhliziyo yakho ebhekana nakho lapho ipompa igazi, okwenza umsebenzi wayo ube lula.

Umuthi ngokuvamile uqala ukusebenza phakathi kwemizuzu engama-30 kuya emahoreni ama-2 ngezinhlobo ezikhishwe ngokushesha, kuyilapho izinguqulo ezikhishwe isikhathi eside zinikeza imiphumela eqhubekayo usuku lonke. Umfutho wakho wegazi awwehli kungazelelwe, okusiza ekuvikeleni isiyezi noma ukukhanya okungase kwenzeke ngeminye imithi.

Kufanele Ngiyithathe Kanjani I-Nifedipine?

Thatha i-nifedipine ngendlela udokotela wakho ayala ngayo, ngokuvamile kanye noma kabili ngosuku kuye ngendlela yokulungiswa. Amaphilisi akhishwe isikhathi eside kufanele agwinywe wonke ngenkomishi yamanzi egcwele futhi akufanele achotshozwe, ahlunywe, noma aphulwe.

Ungathatha i-nifedipine ngokudla noma ngaphandle kokudla, nakuba ukuyithatha ngokudla kungasiza ekunciphiseni isisu uma uhlangabezana nanoma yini. Abanye abantu bathola ukuthi ukuyithatha ngesikhathi esifanayo nsuku zonke kubasiza ukuthi bakhumbule futhi bagcine amazinga emithi aqhubekayo.

Gwema ama-grapefruit nejusi lama-grapefruit ngenkathi uthatha i-nifedipine, ngoba angakhuphula imiphumela yomuthi futhi angase abangele ukuthi umfutho wegazi lakho wehle kakhulu. Lokhu kusebenzisana kwenzeka ngoba ama-grapefruit athinta indlela isibindi sakho esisebenzisa ngayo umuthi.

Uma uthatha uhlobo olukhishwe isikhathi eside, ungase uqaphele igobolondo lethebhulethi elingenalutho endleni yakho. Lokhu kujwayelekile ngokuphelele futhi kusho ukuthi umuthi umuncwe kahle ohlelweni lwakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Nifedipine?

Abantu abaningi bathatha i-nifedipine izinyanga noma iminyaka, njengoba umfutho wegazi ophezulu kanye ne-angina ngokuvamile kuyizimo zesikhathi eside ezidinga ukuqhubeka nokuphathwa. Udokotela wakho uzoqapha impendulo yakho futhi alungise uhlelo lwakho lokwelapha njengoba kudingeka.

Ubude bokwelashwa buxhomeke esimweni sakho esithile nokuthi usabela kahle kangakanani emuthini. Abanye abantu bangase badinge ukuyithatha unomphela ukuze bagcine amazinga omfutho wegazi enempilo, kanti abanye bangase bagcine behlisa umthamo wabo noma bashintshe imithi.

Ungayeki ukuthatha i-nifedipine kungazelelwe ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela ukuthi umfutho wegazi lakho ukhuphuke noma ubuhlungu besifuba bubuye, okungaba yingozi enhliziyweni yakho nasempilweni yakho yonke.

Yiziphi Imiphumela Eceleni Ye-Nifedipine?

Njengayo yonke imithi, i-nifedipine ingabangela imiphumela emibi, nakuba abantu abaningi behlangabezana nezinkinga ezimbalwa noma ezingekho. Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uyithole, iqala ngalezo ezivamile kakhulu:

• Ukuvuvukala emaqakaleni akho, izinyawo, noma izandla (i-edema)
• Ikhanda, ikakhulukazi uma uqala umuthi
• Isiyezi noma ukukhathala lapho usukuma
• Ukuzizwa ukhathele noma ubuthakathaka
• Ukubomvu noma ukuzwa ufudumele
• Isicanucanu noma ukuphatheka kabi kwesisu
• Ama-cramps emisipha noma ubuhlungu obuhlangene

Lezi zinto ezivamile ngokuvamile ziba ngaphansi uma umzimba wakho ujwayela imithi. Uma ziqhubeka noma ziba yinkinga, udokotela wakho angavame ukulungisa umthamo wakho noma asikisela izindlela zokuphatha zona.

Abanye abantu bangase bahlangabezane nemiphumela engavamile kodwa ekhathazayo edinga ukunakekelwa kwezokwelapha:

• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isiyezi esikhulu noma ukuquleka
• Ubuhlungu besifuba noma ukuqina
• Ukuphefumula kanzima
• Ukuvuvukala okukhulu okungathuthuki
• Izimpawu zezinkinga zesibindi (ukuphuzi kwesikhumba noma amehlo, umchamo omnyama)

Ngokuvamile, abanye abantu bangase bahlangabezane nokusabela okukhulu komzimba okuhlanganisa ukuqubuka, ukuluma, ukuvuvukala kobuso noma umphimbo, noma ubunzima bokuphefumula. Uma uqaphela noma yiziphi zalezi zimpawu, funa ukunakekelwa kwezokwelapha ngokushesha.

Ubani Ongafanele Athathe i-Nifedipine?

I-Nifedipine ayifanele wonke umuntu, futhi izimo ezithile noma izimo ziyenza ingaphephile. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuchazela lo muthi.

Abantu okufanele bagweme i-nifedipine bahlanganisa labo abanomfutho wegazi ophansi kakhulu, izinhlobo ezithile zezinkinga zokushaya kwenhliziyo, noma ukuhluleka kwenhliziyo okukhulu. Umuthi ungenza lezi zimo zibe zimbi ngokwehlisa umfutho wegazi noma ukuthinta ukusebenza kwenhliziyo.

Uma ukhulelwe noma uhlela ukukhulelwa, xoxa ngalokhu nodokotela wakho njengoba i-nifedipine ingase ingabi yindlela engcono kakhulu ngesikhathi sokukhulelwa. Ngenkathi ngezinye izikhathi isetshenziswa ekukhulelweni ngezimo ezithile, eminye imithi ingase ibe yizinketho eziphephile.

Abantu abanezifo zesibindi bangase badinge ukulungiswa komthamo noma ukwelashwa okuhlukile, njengoba isibindi sisebenzisa i-nifedipine. Ngokufanayo, abadala bavame ukudinga imithamo ephansi ngenxa yokuthi imizimba yabo iphatha imithi ngendlela ehlukile.

Amagama Omkhiqizo we-Nifedipine

I-Nifedipine itholakala ngaphansi kwamagama amaningi emikhiqizo, okujwayelekile kakhulu yi-Adalat CC, Procardia, kanye ne-Procardia XL. Le mikhiqizo ehlukene ivame ukubhekisela ezinhlobonhlobo zokwakheka komuthi ofanayo.

I-Adalat CC kanye ne-Procardia XL yizinhlobo ezikhishwa kancane kancane ozithatha kanye ngosuku, kanti i-Procardia ejwayelekile iyindlela ekhishwa ngokushesha evame ukuthathwa izikhathi eziningi ngosuku. Udokotela wakho uzocacisa ukuthi yiluphi uhlobo nomkhiqizo ongcono kakhulu esimweni sakho.

Izinhlobo ezivamile ze-nifedipine nazo ziyatholakala futhi zisebenza ngempumelelo njengezinhlobo ezinamagama emikhiqizo. Ukukhetha phakathi kwegama elivamile nelomkhiqizo kuvame ukuncika ekuhlinzekweni komshwalense wakho nakuzintandokazi zakho.

Ezinye izindlela ze-Nifedipine

Uma i-nifedipine ingasebenzi kahle kuwe noma ibangela imiphumela emibi, imithi eminingi ehlukile ingelapha umfutho wegazi ophezulu kanye ne-angina. Udokotela wakho angase ancome ezinye izithiyo zomgudu we-calcium njenge-amlodipine noma i-diltiazem.

Ezinye izigaba zemithi yomfutho wegazi zihlanganisa ama-ACE inhibitors (njenge-lisinopril), ama-ARB (njenge-losartan), ama-beta-blockers (njenge-metoprolol), kanye nama-diuretics (njenge-hydrochlorothiazide). Isigaba ngasinye sisebenza ngendlela ehlukile futhi singase sifaneleke kakhulu ngokuya ngezidingo zakho zempilo ezithile.

Nge-angina, ezinye izindlela zingase zihlanganise ama-beta-blockers noma ama-nitrate asebenza isikhathi eside. Kwesinye isikhathi, inhlanganisela yemithi isebenza kangcono kunomuthi owodwa, futhi udokotela wakho uzosebenza nawe ukuthola indlela esebenza kahle kakhulu.

Ingabe i-Nifedipine ingcono kune-Amlodipine?

Kokubili i-nifedipine ne-amlodipine ziyizithiyo zomgudu we-calcium eziphatha ngempumelelo umfutho wegazi ophezulu kanye ne-angina, kodwa zinezinye izinto ezingenza enye ifaneleke kakhulu kuwe kunenye.

I-Amlodipine ngokuvamile ibangela ukuvuvukala okuncane kwamaqakala futhi inesikhathi eside sokusebenza, okusho ukuthi ihlala esimisweni sakho isikhathi eside futhi inikeze ukulawulwa komfutho wegazi okuqhubekayo. Iphinde ithathwe kanye ngosuku, okutholakala abantu abaningi kulula.

I-Nifedipine, ikakhulukazi izinhlobo ezikhishwa kancane kancane, ingasebenza kahle kakhulu futhi ingase ithandwe uma uke waba nemiphumela emibi nge-amlodipine. Abanye abantu basabela kangcono emuthini owodwa kunomunye, yize besebenza ngendlela efanayo.

Ukukhetha phakathi kwale mithi kuvame ukuncika ekuphenduleni kwakho ngakunye, uhlu lwemiphumela emibi, nezinye izimo zempilo. Udokotela wakho uzocabangela lezi zici lapho enquma ukuthi yini engcono kakhulu esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Nifedipine

Ingabe i-Nifedipine iphephile kubantu abanesifo sikashukela?

Yebo, i-nifedipine ngokuvamile iphephile kubantu abanesifo sikashukela futhi ayithinti amazinga kashukela egazi njengoba eminye imithi yokwehlisa umfutho wegazi ingenza. Eqinisweni, ingase ithandwe ngaphezu kwama-beta-blockers athile angase afihle izimpawu zikashukela ophansi.

Abantu abanesifo sikashukela bavame ukuba nomfutho wegazi ophezulu futhi, futhi ukulawula zombili izimo kubalulekile empilweni yesikhathi eside. I-Nifedipine ingaba yingxenye esebenzayo yokuphatha umfutho wegazi ophezulu ezigulini ezinomdlavuza ngaphandle kokuphazamisa imithi yesifo sikashukela.

Ngingenzani uma ngiphuzile i-Nifedipine eningi ngengozi?

Uma ngengozi uphuza i-nifedipine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ikakhulukazi uma uhlangabezana nezimpawu ezinjengokugcwala ikhanda okukhulu, ukuquleka, noma ukushaya kwenhliziyo okusheshayo.

Ukweqisa kungabangela umfutho wegazi ophansi ngendlela eyingozi, ngakho kubalulekile ukufuna usizo lwezokwelapha ngokushesha. Ungazami ukuzelapha ngokweqisa, futhi ungaqali ukuhlanza ngaphandle uma uqondiswe ngqo uchwepheshe wezempilo.

Ngingenzani uma ngiphuthelwa umthamo we-Nifedipine?

Uma uphuthelwa umthamo we-nifedipine, uyithathe ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuyisikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe, ngoba lokhu kungabangela ukuthi umfutho wegazi lakho wehle kakhulu. Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule.

Ngingayeka nini ukuthatha i-Nifedipine?

Kufanele uyeke kuphela ukuthatha i-nifedipine ngaphansi kokuqondisa kukadokotela wakho, ngoba ukuyeka kungazelelwe kungabangela ukuthi umfutho wegazi lakho ukhuphuke noma ubuhlungu besifuba bubuye. Udokotela wakho uzokwehlisa kancane umthamo wakho uma ukuyeka kufanelekile.

Isinqumo sokuyeka i-nifedipine sincike ezintweni ezinjengokuthi umfutho wegazi lakho ulawulwa kahle kangakanani, ukuthi ngabe wenze izinguquko eziphumelelayo zokuphila, nempilo yakho yonke yenhliziyo nemithambo yegazi. Abanye abantu bangase badinge ukuthatha imithi yomfutho wegazi impilo yabo yonke.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Nifedipine?

Kungcono ukukhawulela ukusetshenziswa kotshwala ngenkathi uthatha i-nifedipine, ngoba utshwala bungathuthukisa imiphumela yokwehlisa umfutho wegazi futhi kwandise ingozi yokugajeka noma ukuquleka. Uma ukhetha ukuphuza, kwenze ngokulinganisela futhi uqaphele ukuthi uzizwa kanjani.

Xhumana nodokotela wakho mayelana nokuthi yiluphi utshwala, uma bukhona, oluphephile kuwe ngenkathi uthatha i-nifedipine. Bangakunikeza isiqondiso esiqondene nawe esisekelwe empilweni yakho yonke neminye imithi ongase uyithathe.