Yini i-Nitazoxanide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Nitazoxanide iyimithi elwa namagciwane elwa nezifo ezibangelwa izilwanyana ezithile kanye namanye amagciwane ohlelweni lwakho lokugaya ukudla. Cabanga ngayo njengokwelashwa okuqondiwe okusiza umzimba wakho ukuthi ususe izinto ezingafuneki ezincane ezingabangela isifo sohudo nokungakhululeki kwesisu.

Le mithi isebenza ngendlela ehlukile kuma-antibiotics ajwayelekile ngoba iqondise ngqo izilwanyana ezinjenge-Giardia ne-Cryptosporidium, okuyizimbangela ezivamile zesifo sohudo esiqhubekayo. Udokotela wakho angase akubhalele i-nitazoxanide uma ukwelashwa okujwayelekile kungasebenzi noma uma ukuhlolwa okuthile kubonisa ukuthi lezi zinhlangano ezithile zibangela izimpawu zakho.

Yini i-Nitazoxanide Esetshenziselwa Yona?

I-Nitazoxanide ngokuyinhloko iphatha isifo sohudo esibangelwa izilwanyana ezimbili ezithile: i-Giardia lamblia ne-Cryptosporidium parvum. Lezi zinhlangano ezincane zingakwenza uzizwe ungaphilile kahle ngezinkinga eziqhubekayo zokugaya ukudla ezingabonakali zithuthuka zodwa.

Izifo ze-Giardia zivame ukwenzeka uma uphuza amanzi angcolile noma udla ukudla okuye kwavezwa yilesi silwanyana. Ungase ukuthole lokhu ngenkathi uhamba, ukhempa, noma ngisho nasemachibini okubhukuda angcolile. Lokhu kutheleleka kungabangela ukuqaqamba, ukuqunjelwa, nezihlalo ezixekile eziqhubeka amasonto.

Izifo ze-Cryptosporidium zisebenza ngendlela efanayo kodwa zivame ukuba yinselele enkulu ukuzelapha, ikakhulukazi kubantu abanezinhlelo zokuzivikela ezibuthakathaka. Lesi silwanyana singabangela isifo sohudo olumanzi olungase luhlale isikhathi eside kunezimbungulu zesisu ezijwayelekile, yingakho udokotela wakho engase akhethe i-nitazoxanide ngokuqondile kulesi simo.

Ngezinye izikhathi odokotela babhala i-nitazoxanide kwezinye izifo zezilwanyana noma ngisho nezifo ezithile zamagciwane, nakuba lokhu kusetshenziswa kungavamile. Umhlinzeki wakho wezempilo uzoqaphela ukuthi le mithi ilungile yini esimweni sakho esithile ngokusekelwe ezimpawini zakho nemiphumela yokuhlolwa.

Isebenza Kanjani i-Nitazoxanide?

I-Nitazoxanide isebenza ngokuhlukumeza ukukhiqizwa kwamandla ngaphakathi kwamapharasayithi namagciwane athile. Ithathwa njengomuthi oqinile ophikisana namapharasayithi ophazamisa indlela lezi zinhlangano ezikhiqiza ngayo amandla abawadingayo ukuze basinde futhi bazale.

Lo muthi uvimba ama-enzyme athile asetshenziswa amapharasayithi ukudala amandla, ngempela ewalambisa ezingeni leselula. Le nqubo yenzeka kancane kancane ezinsukwini eziningana, yingakho uzodinga ukuthatha inkambo ephelele ngisho noma uqala ukuzizwa ungcono ngokushesha.

Ngokungafani neminye imithi enokhahlo, i-nitazoxanide ivame ukubekezeleleka kahle ngoba iqondisa izinqubo eziyingqayizivele kumapharasayithi futhi ayithinti ngokuphawulekayo imisebenzi yakho ejwayelekile yomzimba. Lesi senzo esikhethiwe sisiza ukunciphisa imiphumela emibi ngenkathi isusa ngempumelelo ukutheleleka.

Kufanele Ngiyithathe Kanjani I-Nitazoxanide?

Thatha i-nitazoxanide ngendlela eqondile udokotela wakho ayichazayo, ngokuvamile kabili ngosuku ngokudla. Ukuyithatha ngokudla kusiza umzimba wakho ukuba umunce umuthi kangcono futhi kunciphisa ithuba lokucasuka kwesisu.

Ungathatha lo muthi nganoma yiluphi uhlobo lokudla, kodwa gwema ukuwuthatha esiswini esingenalutho ngoba lokhu kungase kubangele isicanucanu noma ukungakhululeki kwesisu. Uma uthatha ifomu eliwuketshezi, nyakazisa ibhodlela kahle ngaphambi kwesilinganiso ngasinye futhi usebenzise idivayisi yokulinganisa eza nayo ukuze uthole ukunemba.

Zama ukuthatha imithamo yakho cishe ngesikhathi esifanayo nsuku zonke, uzihlukanise ngamahora angaba ngu-12. Lesi sikhathi esiqhubekayo sisiza ukugcina amazinga aqinile omuthi ohlelweni lwakho, okubalulekile ekulweni ngempumelelo ukutheleleka.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Uma unenkinga yokugwinya amaphilisi, buza usokhemisi wakho mayelana nefomu lokumiswa oluwuketshezi, okungenzeka ukuthi kulula ukulithatha.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Nitazoxanide?

Abantu abaningi bathatha i-nitazoxanide izinsuku ezintathu, nakuba udokotela wakho angalungisa lokhu kuye ngokuthi ukutheleleka kwakho kunjani nokuthi usabela kanjani emuthini. Le nkambo emfushane ngokulinganiselwe ivame ukwanele ukususa izifo eziningi zamapharasayithi.

Kubalulekile ukuqeda yonke inkambo ebekiwe ngisho noma uqala ukuzizwa ngcono ngemva kosuku olulodwa noma ezimbili nje. Ukuyeka ngaphambi kwesikhathi kungavumela amapharasayithi ukuthi abuye futhi kungenzeka ukuthi athuthukise ukumelana nomuthi.

Ezifweni ezithile noma kubantu abanezinhlelo zokuzivikela ezikhubazekile, udokotela wakho angase enze ukwelashwa kube yizinsuku ezinhlanu noma ngaphezulu. Izingane nabantu abadala ngokuvamile balandela isimiso esifanayo sezinsuku ezintathu, nakuba umthamo uzolungiswa ngokusekelwe eminyakeni nangesisindo.

Uma izimpawu zakho zingathuthuki ngemva kokuqeda inkambo ephelele, xhumana nomhlinzeki wakho wezempilo. Bangase badinge ukwenza ezinye izivivinyo noma bacabange ngezindlela zokwelapha ezingezinye.

Yiziphi Imiphumela Eceleni ye-Nitazoxanide?

Abantu abaningi bayayibekezelela i-nitazoxanide kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela emibi engathi sína ayivamile, futhi abantu abaningi bathola kuphela izimpawu ezithambile, zesikhashana uma zikhona nhlobo.

Imiphumela emibi evamile ongase uyithole ihlanganisa ukuphazamiseka kwesisu okuncane, isicanucanu, noma ikhanda. Lezi zimpawu ngokuvamile zizixazulula zodwa njengoba umzimba wakho uzivumelanisa nomuthi futhi ngokuvamile azibi nzima ngokwanele ukudinga ukuyeka ukwelashwa.

Nansi imiphumela emibi ongase uhlangabezane nayo, ihlelwe ngokuthi ivamile kangakanani:

Imiphumela emibi evamile (ethinta kufika kumuntu oyedwa kwabayi-10):

• Ubuhlungu besisu noma ukuqaqamba
• Isicanucanu noma ukuhlanza okuncane
• Ikhanda
• Isiyezi
• Ushintsho lombala womchamo (umbala ophuzi)

Imiphumela emibi engavamile (ethinta kufika kumuntu oyedwa kwabayi-100):

• Ukuqunjelwa noma izitulo ezixekile
• Ukukhathala noma ukudinwa
• Ukuqubuka kwesikhumba okuncane
• Ushintsho lokudla
• Umkhuhlane omncane

Imiphumela engavamile (ethinta abantu abangaphansi koyedwa kwabayi-1000):

• Ukungezwani komzimba okukhulu okunezinkinga zokuphefumula noma ukuvuvukala
• Ubuhlungu obukhulu besisu
• Ukuphalaza okuqhubekayo
• Ushintsho olukhulu esigqi senhliziyo
• Ukuphendula kwesikhumba okukhulu noma ukuqubuka okusabalalele

Umbala ophuzi emchamweni wakho empeleni ujwayelekile futhi awuyingozi uma uthatha i-nitazoxanide. Lolu shintsho lombala lwenzeka ngenxa yokuthi umzimba wakho uyikhiqiza kanjani imithi futhi izobuyela kokujwayelekile ngemva kokuqeda inkambo yakho.

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nokungezwani komzimba okukhulu, ukuphalaza okuqhubekayo, noma ubuhlungu obukhulu besisu. Le miphumela engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha okusheshayo.

Ubani Ongafanele Athatha I-Nitazoxanide?

I-Nitazoxanide ngokuvamile iphephile kubantu abaningi, kodwa abantu abathile kufanele bagweme le mithi noma bayisebenzise ngokuqapha okwengeziwe. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha ukuze aqinisekise ukuthi iphephile kuwe.

Akufanele uthathe i-nitazoxanide uma unokungezwani komzimba kule mithi noma kunoma yiziphi izithako zayo. Izimpawu zokungezwani komzimba zihlanganisa imihuzuko, ubunzima bokuphefumula, noma ukuvuvukala kobuso bakho, izindebe, ulimi, noma umphimbo.

Abantu abanezifo ezinzima zezinso noma zesibindi badinga ukucatshangelwa okukhethekile, njengoba lezi zitho zisiza ekucubunguleni imithi. Udokotela wakho angase alungise umthamo wakho noma akhethe enye indlela yokwelapha uma unezinkinga ezinkulu ngalezi zitho.

Uma ukhulelwe noma uncelisa, xoxa ngezingozi nezinzuzo nomhlinzeki wakho wezempilo. Nakuba i-nitazoxanide ibonakala iphephile ngesikhathi sokukhulelwa, udokotela wakho uzohlola ukuthi izinzuzo zidlula yini noma yiziphi izingozi ezingase zibe khona kuwe nomntwana wakho.

Izingane ezingaphansi kwezinyanga eziyi-12 ubudala akufanele zithole i-nitazoxanide ngaphandle uma ziqondiswa ngqo uchwepheshe wezingane. Imithi ayizange ifundwe kabanzi ezinsaneni ezisencane kakhulu, ngakho ukwelashwa okuhlukile kuvame ukukhethwa.

Amagama Omkhiqizo we-Nitazoxanide

Igama lomkhiqizo elivame kakhulu le-nitazoxanide yi-Alinia, etholakala ngesimo samaphilisi kanye nokumiswa okunguketshezi. Lo mkhiqizo utholakala kabanzi emakhemisi amaningi futhi yiwona ovame ukunconywa odokotela.

Ezinye izinhlobo ze-nitazoxanide ezivamile nazo ziyatholakala, eziqulathe isithako esifanayo esisebenzayo kodwa zingase zibe ngentengo ephansi. Umuthi wakho wemithi angakusiza ukuthi uqonde ukuthi iyiphi inguqulo ehlanganiswa ngumshuwalense wakho nokuthi ngabe izinketho ezivamile ziyatholakala yini.

Ukwakheka okunguketshezi kusiza ikakhulukazi izingane noma abantu abadala abanobunzima bokugwinya amaphilisi. Zombili izinhlobo zisebenza kahle ngokulinganayo, ngakho-ke khetha leyo okulula ukuyithatha njalo.

Ezinye izindlela ze-Nitazoxanide

Kukhona ezinye izindlela zokwelapha izifo ezinamapharasayithi, yize ukukhetha okungcono kuncike epharasyithi ethile ebanga izimpawu zakho. Udokotela wakho uzokhetha ukwelashwa okufanele kakhulu ngokuya ngemiphumela yakho yokuhlolwa nomlando wakho wezokwelapha.

Ezifweni ze-Giardia, i-metronidazole (Flagyl) ingenye inketho esetshenziswa kakhulu esesikhona isikhathi eside kune-nitazoxanide. Abanye abantu bathola ukuthi i-metronidazole ibangela ukuphazamiseka okwengeziwe kwesisu, kodwa iyasebenza ngokulinganayo ezifweni eziningi ze-Giardia.

I-Tinidazole enye indlela esebenza kahle nge-Giardia futhi ingase ibangele imiphumela emibi embalwa kune-metronidazole. Ivame ukunikezwa njengomthamo owodwa, ongaba lula kunezindlela zokwelapha zezinsuku eziningi.

Ezifweni ze-Cryptosporidium, izinketho zokwelapha zilinganiselwe kakhulu, futhi i-nitazoxanide ivame ukuba yiyo ekhethwayo. Kubantu abanezinhlelo zokuzivikela ezinhle, kwesinye isikhathi ukunakekelwa okusekelayo kuphela kwanele, kugxilwe ekuhlaliseni amanzi ngesikhathi sokutheleleka kucaca ngokwemvelo.

I-Paromomycin ngezinye izikhathi isetshenziselwa i-Cryptosporidium, ikakhulukazi kubantu abanezinhlelo zokuzivikela ezikhubazekile, yize ngokuvamile ingasebenzi kahle kune-nitazoxanide ngale pharasayithi ethile.

Ingabe i-Nitazoxanide ingcono kune-Metronidazole?

Kokubili i-nitazoxanide ne-metronidazole ziyizindlela zokwelapha ezisebenzayo zokutheleleka ngamapharasayithi, kodwa ngalinye linokuhle okuhlukile kuye ngesimo sakho esithile. Akukho noyedwa 'ongcono' kunomunye.

I-Nitazoxanide ivame ukubangela imiphumela emincane, ikakhulukazi ukungabi namahloni nokukhathazeka kwesisu uma kuqhathaniswa ne-metronidazole. Abantu abaningi bakuthola kulula ukuqeda inkambo ephelele ye-nitazoxanide ngoba ivame ukubekezelelwa kangcono.

I-Metronidazole isetshenziswe isikhathi eside futhi isebenza kahle ngokumelene nohlu olubanzi lwama-parasites namagciwane. Futhi ngokuvamile ibiza kancane kune-nitazoxanide futhi ingase ihlanganiswe kalula yizinhlelo zomshuwalense.

Ezifweni ze-Giardia, womabili amakhambi asebenza kahle ngokulinganayo ezimweni eziningi. Udokotela wakho angase akhethe i-nitazoxanide uma uke waba nezinkinga zesisu nge-metronidazole esikhathini esidlule, noma uma uthatha eminye imithi engase ihlangane ne-metronidazole.

Ezifweni ze-Cryptosporidium, i-nitazoxanide ivame ukukhethwa ngoba i-metronidazole ayisebenzi kahle ngokumelene nale parasite ethile. Udokotela wakho uzocabangela inhlangano ethile ebangela ukutheleleka kwakho lapho ekhetha phakathi kwalezi zinketho.

Imibuzo Evame Ukubuzwa Mayelana ne-Nitazoxanide

Q1. Ingabe i-Nitazoxanide iphephile ku-Diabetes?

I-Nitazoxanide ngokuvamile iphephile kubantu abanesifo sikashukela, njengoba ingawathinti kakhulu amazinga kashukela egazini. Kodwa-ke, kufanele uqaphele ushukela wakho wegazi njengenjwayelo, ikakhulukazi uma ungadli kahle ngenxa yokutheleleka kwamathumbu akho.

Ifomu lokumiswa oluketshezi liqukethe inani elincane likashukela, ngakho-ke uma uthatha leli fomu, ungase ufune ukubala lawo ma-carbohydrate engeziwe ohlelweni lwakho lokuphatha isifo sikashukela. Inani lincane futhi akunakwenzeka ukuthi libangele izinkinga kubantu abaningi abanesifo sikashukela.

Njalo yazisa udokotela wakho ngesifo sakho sikashukela kanye nanoma imiphi imithi oyithathayo ukuze usilawule. Bangakunikeza iseluleko esiqondene nawe mayelana nokuqapha ushukela wakho wegazi ngenkathi uthatha i-nitazoxanide.

Q2. Kufanele Ngenzeni Uma Ngithatha I-Nitazoxanide Eningi Ngengozi?

Uma ngengozi uthatha i-nitazoxanide eningi, xhumana nomhlinzeki wakho wokunakekelwa kwezempilo noma isikhungo sokulawula ubuthi ngokushesha. Nakuba ukweqisa okukhulu kungavamile, kubalulekile ukuthola isiqondiso sezokwelapha ngokushesha.

Ukuthatha umthamo ophezulu kancane kunalowo oqokiwe ngokuvamile ngeke kubangele ukulimala okukhulu, kodwa ungase uzwe ukuquleka kwesisu okwandayo, isicanucanu, noma isiyezi. Ungazami ukuthi "ukwenza ngaphezulu" ukweqisa ngokweqa imithamo yesikhathi esizayo.

Uma uthathe okuningi kakhulu kunalokho okuchaziwe noma uma uhlangabezana nezimpawu ezinzima njengokuhlanza okuqhubekayo, ubuhlungu obukhulu besisu, noma ubunzima bokuphefumula, funa ukunakekelwa kwezimo eziphuthumayo ngokushesha.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Nitazoxanide?

Uma uphuthelwa umthamo we-nitazoxanide, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma kungasondeli isikhathi somthamo wakho olandelayo. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Uma kungaphakathi kwamahora angu-4 omthamo wakho olandelayo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho evamile. Ukuthatha imithamo eseduze kakhulu kungakhuphula ingozi yakho yemiphumela emibi ngaphandle kokuthuthukisa ukusebenza kahle komuthi.

Zama ukugcina isikhathi esiqhubekayo semithamo yakho ukuze ugcine amazinga aqhubekayo omuthi ohlelweni lwakho. Ukusetha ama-alamu ocingweni noma ukuthatha imithamo yakho ngokudla kungakusiza ukuthi ukhumbule.

Q4. Ngingayeka Nini Ukuthatha I-Nitazoxanide?

Kufanele uqedele inkambo yonke echaziwe ye-nitazoxanide, ngisho noma uzizwa ungcono ngokuphelele ngaphambi kokuqeda yonke imithamo. Ukuyeka ngaphambi kwesikhathi kungavumela izinambuzane ukuthi zibuye futhi zikwazi ukumelana nomuthi.

Izifundo eziningi zithatha izinsuku ezintathu, futhi kubalulekile ukuthatha zonke izilinganiso eziyisithupha (kabili ngosuku izinsuku ezintathu) njengoba kunqunyiwe. Amapharasayithi angase abe khona ngamanani amancane ngisho nangemva kokuba izimpawu zakho zithuthuke.

Uma uhlangabezana nemiphumela emibi kakhulu okwenza kube nzima ukuqhubeka nomuthi, xhumana nodokotela wakho ngaphambi kokuyeka. Bangakunika iseluleko sokuthi ngabe kuphephile yini ukuyeka noma ngabe udinga ukushintshela ekwelashweni okuhlukile.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Nitazoxanide?

Ngenkathi kungekho ukusebenzisana okuqondile phakathi kwe-nitazoxanide notshwala, ngokuvamile kungcono ukugwema ukuphuza utshwala ngenkathi usalulama ekuthelelekeni ngeparasitic. Utshwala bungase buqhubekise ukoma nokukhathazeka kwesisu, okuyizinto ezivele zikhathaza uma unokutheleleka emathunjini.

Utshwala bungase futhi buphazamise ikhono lomzimba wakho lokulwa nokutheleleka ngempumelelo. Umzimba wakho udinga ukugxila emandleni awo ekupholiseni, futhi utshwala bungakwenza lokhu kube nzima.

Uma ukhetha ukuphuza utshwala, kwenze ngokulinganisela futhi uqinisekise ukuthi uhlala unamanzi ngamanzi kanye nezinye iziphuzo ezingezona utshwala. Kodwa-ke, kungcono ngempela ukulinda uze uqede ukwelashwa kwakho futhi uzizwe kahle ngokuphelele.