Obinutuzumab (indlela ye-intravenous)
Imikhiqizo etholakalayo
Gazyva
Mayelana naleli khambi
Isikhubekiso se-Obinutuzumab sisetshenziswa ndawonye nezinye izidakamizwa (isib. i-chlorambucil) ukuze kuphathwe ukugula kwe-chronic lymphocytic leukemia (CLL). Isikhubekiso se-Obinutuzumab sisetshenziswa futhi ndawonye ne-bendamustine ukuze kuphathwe i-follicular lymphoma ngemva kokuthi ezinye izidakamizwa (isib. i-rituximab) zingasebenzi kahle. Sisetshenziswa futhi ukuze kuphathwe iziguli ezazinesifo se-stage II bulky, III noma IV follicular lymphoma esingaphathwanga futhi okungenani zithola impumuzo yesikhashana (ukukhululeka) ekushayweni yazo. Yenza kube nzima ukukhula kwamaseli omdlavuza, aqedwa ekugcineni umzimba. I-Obinutuzumab iyilungu leqembu le-antineoplastic (umuthi womdlavuza). Lo muthi kufanele unikezwe kuphela ngudokotela wakho noma ngaphansi kokunakekelwa kwakhe okuqondile. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, kubalulekile ukuqhathanisa izingozi zokusebenzisa imithi nezinzuzo ezingaba khona. Lo ngumqulu ozokwenziwa wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nokuthile okungavamile noma ukuzwela okukhulu kule mithi noma kwezinye izidakamizwa. Tshela ochwepheshe bakho bezempilo uma unezinye izinhlobo zokuzwela, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenalo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Akwenziwanga ucwaningo olufanele mayelana nobudlelwano phakathi nobudala nemiphumela yokubeka i-obinutuzumab kubantwana. Ukuphepha nokuphumelela akukaqiniswa. Ucwaningo olufanele oluqediwe kuze kube manje alubonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-obinutuzumab injection kubantu abadala. Ayikho izifundo ezanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Tshela ochwepheshe bakho bezempilo uma uthatha ezinye izidakamizwa eziresiphi noma ezingenasiphi (ezithengiswa ngaphandle kwelayisensi [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba ngezinye izidakamizwa kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Umshula wesibeletho noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka ngalolu lwemi indawo yokwelapha noma esikhungweni sokwelapha umdlavuza. Lolu lwemi lunikezwa ngenhlanzi ebekwe kwenye yezinsimbi zakho. Ungase futhi uthole izinto ezigeleza ezengeziwe nezinye izidakamizwa (isib. imithi yokwelapha ukungezwani, imithi yokwelapha ubushushu, imithi yokwelapha isifo sikagout, ama-steroids) ukusiza ukuvimbela imiphumela emibi engathandeki evela ekugonyweni. Ungasebenzisi imithi yegazi eliphakeme amahora angu-12 ngaphambi kokuthola, phakathi, nangehora eli-1 ngemuva kokuthola lolu lwemi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.